[ { "phenotype_id": "PH1474", "phenotype_version_id": 4101, "name": "Death by diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (natural cause)", "definition": "Causes of deaths are ICD-10 codes associated with the “underlying cause of death” from the Office for National Statistics death registry. Based on a previous study (John et al., 2018), causes of deaths are first grouped into natural and unnatural main categories and then further grouped in accordance with the respective chapters of ICD-10: \n\n# Natural causes\n- [Deaths by certain infectious and parasitic diseases (natural cause) [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3230/detail/) ICD-10 codes: A00-B99\n- [Deaths by neoplasms (natural cause) [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3231/detail/) ICD-10 codes: C00-D48\n- [Deaths by diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (natural cause) [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3232/detail/) **Current concept** ICD-10 codes: D50-D89\n- [Deaths by endocrine, nutritional and metabolic diseases (natural cause) [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3233/detail/) ICD-10 codes: E00-E88\n- [Deaths by mental and behavioural disorders (natural cause) [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3234/detail/) ICD-10 codes: F01-F99\n- [Deaths by diseases of the nervous system (natural cause) [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3235/detail/) ICD-10 codes: G00-G99\n- [Deaths by diseases of the eye and adnexa (natural cause) [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3236/detail/) ICD-10 codes: H00-H57\n- [Deaths by diseases of the ear and mastoid process (natural cause) [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3237/detail/) ICD-10 codes: H60-H93\n- [Deaths by diseases of the circulatory system (natural cause) [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3238/detail/) ICD-10 codes: I00-I99\n- [Deaths by diseases of the respiratory system (natural cause) [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3239/detail/) ICD-10 codes: J00-J99\n- [Deaths by diseases of the digestive system (natural cause) [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3240/detail/) ICD-10 codes: K00-K92\n- [Deaths by diseases of the skin and subcutaneous tissue (natural cause) [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3241/detail/) ICD-10 codes: L00-L98\n- [Deaths by diseases of the musculoskeletal system and connective tissue (natural cause) [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3242/detail/) ICD-10 codes: M00-M99\n- [Deaths by diseases of the genitourinary system (natural cause) [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3243/detail/) ICD-10 codes: N00-N99\n- [Deaths by pregnancy, childbirth and the puerperium (natural cause) [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3244/detail/) ICD-10 codes: O00-O99\n- [Deaths by certain conditions originating in the perinatal period (natural cause) [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3245/detail/) ICD-10 codes: P00-P96\n- [Deaths by congenital malformations, deformations and chromosomal abnormalities (natural cause) [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3246/detail/) ICD-10 codes: Q00-Q99\n- [Deaths by symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (natural cause) [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3247/detail/) ICD-10 codes: R00-R99\n# Unnatural causes\n- [Deaths by accidents (unnatural cause) [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3248/detail/) ICD-10 codes: V01-X59, Y85-Y86\n- [Deaths by assaults (unnatural cause) [ICD10]\n- (https://conceptlibrary.saildatabank.com/concepts/C3249/detail/) ICD-10 codes: X85-Y09\n- [Deaths by complications of medical and surgical care (unnatural cause) [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3250/detail/) ICD-10 codes: Y40-Y88\n- [Deaths by suicide Please refer to relevant concept(s) for death by suicide: Deaths by suicide - Intentional self-harm [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3208/detail/)\n- Deaths by suicide - Undetermined intent]()\n- [Deaths by suicide - Undetermined intent (pre-2007) [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3209/detail/)\n- [Deaths by suicide - Undetermined intent (2007-onward) [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3210/detail/)\n- [Deaths by suicide - Accidental verdicts [ICD10]](https://conceptlibrary.saildatabank.com/concepts/C3211/detail/) \n\nAs discussed with a clinician in the study team ([Prof Ann John](https://www.swansea.ac.uk/staff/a.john/)), all codes related to deaths by suicide but with age of death not complying with the corresponding age criteria should be regarded as deaths by unknown causes. References [John, A., McGregor, J., Jones, I., Lee, S.C., Walters, J.T., Owen, M.J., O'Donovan, M., DelPozo-Banos, M., Berridge, D. & Lloyd, K. (2018)](https://doi.org/10.1016/j.schres.2018.04.009). Premature mortality among people with severe mental illness — New evidence from linked primary care data. *Schizophrenia Research*, *199*, 154-162.", "implementation": "", "publications": [ { "doi": "https://doi.org/10.1016/j.schres.2018.04.009", "details": "https://www.sciencedirect.com/science/article/pii/S0920996418301981" } ], "validation": "", "citation_requirements": "", "created": "2023-10-11T10:44:50.107130Z", "author": "John, A, McGregor, J., Jones, I., Lee, S. C., Walters, J. T. R., Owen, M. J., O'Donovan, M., DelPozo-Banos, M., Berridge, D., & Lloyd, K.", "collections": [ { "name": "Adolescent Data Platform (ADP)", "value": 23 }, { "name": "DATAMIND", "value": 27 }, { "name": "Phenotype Library", "value": 18 } ], "tags": null, "organisation": { "id": 2, "slug": "adp", "name": "ADP" }, "world_access": 1, "updated": "2023-11-13T20:05:40.058093Z", "sex": [ { "name": "Both", "value": "3" } ], "type": [ { "name": "Disease or syndrome", "value": "2" } ], "ontology": null, "phenoflowid": null, "data_sources": null, "coding_system": [ { "name": "ICD10 codes", "value": 4 } ], "event_date_range": "", "concept_information": [ { "concept_id": 3232, "concept_version_id": 8949, "concept_name": "Death by diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (natural cause) [ICD10]", "coding_system": { "id": 4, "name": "ICD10 codes", "description": "ICD10 Codes" }, "phenotype_id": "PH1474", "phenotype_version_id": 4101, "phenotype_name": "Death by diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (natural cause)", "code_attribute_header": [], "codes": [ { "code": "D50", "description": "Iron deficiency anaemia ", "attributes": null }, { "code": "D50.0", "description": "Iron deficiency anaemia | Iron deficiency anaemia secondary to blood loss (chronic)", "attributes": null }, { "code": "D50.1", "description": "Iron deficiency anaemia | Sideropenic dysphagia", "attributes": null }, { "code": "D50.8", "description": "Iron deficiency anaemia | Other iron deficiency anaemias", "attributes": null }, { "code": "D50.9", "description": "Iron deficiency anaemia | Iron deficiency anaemia, unspecified", "attributes": null }, { "code": "D51", "description": "Vitamin B12 deficiency anaemia ", "attributes": null }, { "code": "D51.0", "description": "Vitamin B12 deficiency anaemia | Vitamin B12 defic anaemia due to intrinsic factor deficiency", "attributes": null }, { "code": "D51.1", "description": "Vitamin B12 deficiency anaemia | Vit B12 def anaem select vit B12 malabsorp with proteinuria", "attributes": null }, { "code": "D51.2", "description": "Vitamin B12 deficiency anaemia | Transcobalamin II deficiency", "attributes": null }, { "code": "D51.3", "description": "Vitamin B12 deficiency anaemia | Other dietary vitamin B12 deficiency anaemia", "attributes": null }, { "code": "D51.8", "description": "Vitamin B12 deficiency anaemia | Other vitamin B12 deficiency anaemias", "attributes": null }, { "code": "D51.9", "description": "Vitamin B12 deficiency anaemia | Vitamin B12 deficiency anaemia, unspecified", "attributes": null }, { "code": "D52", "description": "Folate deficiency anaemia ", "attributes": null }, { "code": "D52.0", "description": "Folate deficiency anaemia | Dietary folate deficiency anaemia", "attributes": null }, { "code": "D52.1", "description": "Folate deficiency anaemia | Drug-induced folate deficiency anaemia", "attributes": null }, { "code": "D52.8", "description": "Folate deficiency anaemia | Other folate deficiency anaemias", "attributes": null }, { "code": "D52.9", "description": "Folate deficiency anaemia | Folate deficiency anaemia, unspecified", "attributes": null }, { "code": "D53", "description": "Other nutritional anaemias ", "attributes": null }, { "code": "D53.0", "description": "Other nutritional anaemias | Protein deficiency anaemia", "attributes": null }, { "code": "D53.1", "description": "Other nutritional anaemias | Other megaloblastic anaemias, not elsewhere classified", "attributes": null }, { "code": "D53.2", "description": "Other nutritional anaemias | Scorbutic anaemia", "attributes": null }, { "code": "D53.8", "description": "Other nutritional anaemias | Other specified nutritional anaemias", "attributes": null }, { "code": "D53.9", "description": "Other nutritional anaemias | Nutritional anaemia, unspecified", "attributes": null }, { "code": "D55", "description": "Anaemia due to enzyme disorders ", "attributes": null }, { "code": "D55.0", "description": "Anaemia due to enzyme disorders | Anaemia due to glucose-6-phosphate dehydrogenase deficiency", "attributes": null }, { "code": "D55.1", "description": "Anaemia due to enzyme disorders | Anaemia due to other disorders of glutathione metabolism", "attributes": null }, { "code": "D55.2", "description": "Anaemia due to enzyme disorders | Anaemia due to disorders of glycolytic enzymes", "attributes": null }, { "code": "D55.3", "description": "Anaemia due to enzyme disorders | Anaemia due to disorders of nucleotide metabolism", "attributes": null }, { "code": "D55.8", "description": "Anaemia due to enzyme disorders | Other anaemias due to enzyme disorders", "attributes": null }, { "code": "D55.9", "description": "Anaemia due to enzyme disorders | Anaemia due to enzyme disorder, unspecified", "attributes": null }, { "code": "D56", "description": "Thalassaemia ", "attributes": null }, { "code": "D56.0", "description": "Thalassaemia | Alpha thalassaemia", "attributes": null }, { "code": "D56.1", "description": "Thalassaemia | Beta thalassaemia", "attributes": null }, { "code": "D56.2", "description": "Thalassaemia | Delta-beta thalassaemia", "attributes": null }, { "code": "D56.3", "description": "Thalassaemia | Thalassaemia trait", "attributes": null }, { "code": "D56.4", "description": "Thalassaemia | Hereditary persistence of fetal haemoglobin [HPFH]", "attributes": null }, { "code": "D56.8", "description": "Thalassaemia | Other thalassaemias", "attributes": null }, { "code": "D56.9", "description": "Thalassaemia | Thalassaemia, unspecified", "attributes": null }, { "code": "D57", "description": "Sickle-cell disorders ", "attributes": null }, { "code": "D57.0", "description": "Sickle-cell disorders | Sickle-cell anaemia with crisis", "attributes": null }, { "code": "D57.1", "description": "Sickle-cell disorders | Sickle-cell anaemia without crisis", "attributes": null }, { "code": "D57.2", "description": "Sickle-cell disorders | Double heterozygous sickling disorders", "attributes": null }, { "code": "D57.3", "description": "Sickle-cell disorders | Sickle-cell trait", "attributes": null }, { "code": "D57.8", "description": "Sickle-cell disorders | Other sickle-cell disorders", "attributes": null }, { "code": "D58", "description": "Other hereditary haemolytic anaemias ", "attributes": null }, { "code": "D58.0", "description": "Other hereditary haemolytic anaemias | Hereditary spherocytosis", "attributes": null }, { "code": "D58.1", "description": "Other hereditary haemolytic anaemias | Hereditary elliptocytosis", "attributes": null }, { "code": "D58.2", "description": "Other hereditary haemolytic anaemias | Other haemoglobinopathies", "attributes": null }, { "code": "D58.8", "description": "Other hereditary haemolytic anaemias | Other specified hereditary haemolytic anaemias", "attributes": null }, { "code": "D58.9", "description": "Other hereditary haemolytic anaemias | Hereditary haemolytic anaemia, unspecified", "attributes": null }, { "code": "D59", "description": "Acquired haemolytic anaemia ", "attributes": null }, { "code": "D59.0", "description": "Acquired haemolytic anaemia | Drug-induced autoimmune haemolytic anaemia", "attributes": null }, { "code": "D59.1", "description": "Acquired haemolytic anaemia | Other autoimmune haemolytic anaemias", "attributes": null }, { "code": "D59.2", "description": "Acquired haemolytic anaemia | Drug-induced nonautoimmune haemolytic anaemia", "attributes": null }, { "code": "D59.3", "description": "Acquired haemolytic anaemia | Haemolytic-uraemic syndrome", "attributes": null }, { "code": "D59.4", "description": "Acquired haemolytic anaemia | Other nonautoimmune haemolytic anaemias", "attributes": null }, { "code": "D59.5", "description": "Acquired haemolytic anaemia | Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]", "attributes": null }, { "code": "D59.6", "description": "Acquired haemolytic anaemia | Haemoglobinuria due to haemolysis from other external causes", "attributes": null }, { "code": "D59.8", "description": "Acquired haemolytic anaemia | Other acquired haemolytic anaemias", "attributes": null }, { "code": "D59.9", "description": "Acquired haemolytic anaemia | Acquired haemolytic anaemia, unspecified", "attributes": null }, { "code": "D60", "description": "Acquired pure red cell aplasia [erythroblastopenia] ", "attributes": null }, { "code": "D60.0", "description": "Acquired pure red cell aplasia [erythroblastopenia] | Chronic acquired pure red cell aplasia", "attributes": null }, { "code": "D60.1", "description": "Acquired pure red cell aplasia [erythroblastopenia] | Transient acquired pure red cell aplasia", "attributes": null }, { "code": "D60.8", "description": "Acquired pure red cell aplasia [erythroblastopenia] | Other acquired pure red cell aplasias", "attributes": null }, { "code": "D60.9", "description": "Acquired pure red cell aplasia [erythroblastopenia] | Acquired pure red cell aplasia, unspecified", "attributes": null }, { "code": "D61", "description": "Other aplastic anaemias ", "attributes": null }, { "code": "D61.0", "description": "Other aplastic anaemias | Constitutional aplastic anaemia", "attributes": null }, { "code": "D61.1", "description": "Other aplastic anaemias | Drug-induced aplastic anaemia", "attributes": null }, { "code": "D61.2", "description": "Other aplastic anaemias | Aplastic anaemia due to other external agents", "attributes": null }, { "code": "D61.3", "description": "Other aplastic anaemias | Idiopathic aplastic anaemia", "attributes": null }, { "code": "D61.8", "description": "Other aplastic anaemias | Other specified aplastic anaemias", "attributes": null }, { "code": "D61.9", "description": "Other aplastic anaemias | Aplastic anaemia, unspecified", "attributes": null }, { "code": "D62", "description": "Acute posthaemorrhagic anaemia ", "attributes": null }, { "code": "D62.X", "description": "Acute posthaemorrhagic anaemia | Acute posthaemorrhagic anaemia", "attributes": null }, { "code": "D63", "description": "Anaemia in chronic diseases classified elsewhere ", "attributes": null }, { "code": "D63.0", "description": "Anaemia in chronic diseases classified elsewhere | Anaemia in neoplastic disease", "attributes": null }, { "code": "D63.8", "description": "Anaemia in chronic diseases classified elsewhere | Anaemia in other chronic diseases classified elsewhere", "attributes": null }, { "code": "D64", "description": "Other anaemias ", "attributes": null }, { "code": "D64.0", "description": "Other anaemias | Hereditary sideroblastic anaemia", "attributes": null }, { "code": "D64.1", "description": "Other anaemias | Secondary sideroblastic anaemia due to disease", "attributes": null }, { "code": "D64.2", "description": "Other anaemias | Secondary sideroblastic anaemia due to drugs and toxins", "attributes": null }, { "code": "D64.3", "description": "Other anaemias | Other sideroblastic anaemias", "attributes": null }, { "code": "D64.4", "description": "Other anaemias | Congenital dyserythropoietic anaemia", "attributes": null }, { "code": "D64.8", "description": "Other anaemias | Other specified anaemias", "attributes": null }, { "code": "D64.9", "description": "Other anaemias | Anaemia, unspecified", "attributes": null }, { "code": "D65", "description": "Dissem intravascular coagulation [defibrination syndrome] ", "attributes": null }, { "code": "D65.X", "description": "Dissem intravascular coagulation [defibrination syndrome] | Dissem intravascular coagulation [defibrination syndrome]", "attributes": null }, { "code": "D66", "description": "Hereditary factor VIII deficiency ", "attributes": null }, { "code": "D66.X", "description": "Hereditary factor VIII deficiency | Hereditary factor VIII deficiency", "attributes": null }, { "code": "D67", "description": "Hereditary factor IX deficiency ", "attributes": null }, { "code": "D67.X", "description": "Hereditary factor IX deficiency | Hereditary factor IX deficiency", "attributes": null }, { "code": "D68", "description": "Other coagulation defects ", "attributes": null }, { "code": "D68.0", "description": "Other coagulation defects | Von Willebrand's disease", "attributes": null }, { "code": "D68.1", "description": "Other coagulation defects | Hereditary factor XI deficiency", "attributes": null }, { "code": "D68.2", "description": "Other coagulation defects | Hereditary deficiency of other clotting factors", "attributes": null }, { "code": "D68.3", "description": "Other coagulation defects | Haemorrhagic disorder due to circulating anticoagulants", "attributes": null }, { "code": "D68.4", "description": "Other coagulation defects | Acquired coagulation factor deficiency", "attributes": null }, { "code": "D68.8", "description": "Other coagulation defects | Other specified coagulation defects", "attributes": null }, { "code": "D68.9", "description": "Other coagulation defects | Coagulation defect, unspecified", "attributes": null }, { "code": "D69", "description": "Purpura and other haemorrhagic conditions ", "attributes": null }, { "code": "D69.0", "description": "Purpura and other haemorrhagic conditions | Allergic purpura", "attributes": null }, { "code": "D69.1", "description": "Purpura and other haemorrhagic conditions | Qualitative platelet defects", "attributes": null }, { "code": "D69.2", "description": "Purpura and other haemorrhagic conditions | Other nonthrombocytopenic purpura", "attributes": null }, { "code": "D69.3", "description": "Purpura and other haemorrhagic conditions | Idiopathic thrombocytopenic purpura", "attributes": null }, { "code": "D69.4", "description": "Purpura and other haemorrhagic conditions | Other primary thrombocytopenia", "attributes": null }, { "code": "D69.5", "description": "Purpura and other haemorrhagic conditions | Secondary thrombocytopenia", "attributes": null }, { "code": "D69.6", "description": "Purpura and other haemorrhagic conditions | Thrombocytopenia, unspecified", "attributes": null }, { "code": "D69.8", "description": "Purpura and other haemorrhagic conditions | Other specified haemorrhagic conditions", "attributes": null }, { "code": "D69.9", "description": "Purpura and other haemorrhagic conditions | Haemorrhagic condition, unspecified", "attributes": null }, { "code": "D70", "description": "Agranulocytosis ", "attributes": null }, { "code": "D70.X", "description": "Agranulocytosis | Agranulocytosis", "attributes": null }, { "code": "D71", "description": "Functional disorders of polymorphonuclear neutrophils ", "attributes": null }, { "code": "D71.X", "description": "Functional disorders of polymorphonuclear neutrophils | Functional disorders of polymorphonuclear neutrophils", "attributes": null }, { "code": "D72", "description": "Other disorders of white blood cells ", "attributes": null }, { "code": "D72.0", "description": "Other disorders of white blood cells | Genetic anomalies of leukocytes", "attributes": null }, { "code": "D72.1", "description": "Other disorders of white blood cells | Eosinophilia", "attributes": null }, { "code": "D72.8", "description": "Other disorders of white blood cells | Other specified disorders of white blood cells", "attributes": null }, { "code": "D72.9", "description": "Other disorders of white blood cells | Disorder of white blood cells, unspecified", "attributes": null }, { "code": "D73", "description": "Diseases of spleen ", "attributes": null }, { "code": "D73.0", "description": "Diseases of spleen | Hyposplenism", "attributes": null }, { "code": "D73.1", "description": "Diseases of spleen | Hypersplenism", "attributes": null }, { "code": "D73.2", "description": "Diseases of spleen | Chronic congestive splenomegaly", "attributes": null }, { "code": "D73.3", "description": "Diseases of spleen | Abscess of spleen", "attributes": null }, { "code": "D73.4", "description": "Diseases of spleen | Cyst of spleen", "attributes": null }, { "code": "D73.5", "description": "Diseases of spleen | Infarction of spleen", "attributes": null }, { "code": "D73.8", "description": "Diseases of spleen | Other diseases of spleen", "attributes": null }, { "code": "D73.9", "description": "Diseases of spleen | Disease of spleen, unspecified", "attributes": null }, { "code": "D74", "description": "Methaemoglobinaemia ", "attributes": null }, { "code": "D74.0", "description": "Methaemoglobinaemia | Congenital methaemoglobinaemia", "attributes": null }, { "code": "D74.8", "description": "Methaemoglobinaemia | Other methaemoglobinaemias", "attributes": null }, { "code": "D74.9", "description": "Methaemoglobinaemia | Methaemoglobinaemia, unspecified", "attributes": null }, { "code": "D75", "description": "Other diseases of blood and blood-forming organs ", "attributes": null }, { "code": "D75.0", "description": "Other diseases of blood and blood-forming organs | Familial erythrocytosis", "attributes": null }, { "code": "D75.1", "description": "Other diseases of blood and blood-forming organs | Secondary polycythaemia", "attributes": null }, { "code": "D75.2", "description": "Other diseases of blood and blood-forming organs | Essential thrombocytosis", "attributes": null }, { "code": "D75.8", "description": "Other diseases of blood and blood-forming organs | Other specified diseases of blood and blood-forming organs", "attributes": null }, { "code": "D75.9", "description": "Other diseases of blood and blood-forming organs | Disease of blood and blood-forming organs, unspecified", "attributes": null }, { "code": "D76", "description": "Certain dis invol lymphoretic tis and reticulohistiocyt sys ", "attributes": null }, { "code": "D76.0", "description": "Certain dis invol lymphoretic tis and reticulohistiocyt sys | Langerhans' cell histiocytosis, not elsewhere classified", "attributes": null }, { "code": "D76.1", "description": "Certain dis invol lymphoretic tis and reticulohistiocyt sys | Haemophagocytic lymphohistiocytosis", "attributes": null }, { "code": "D76.2", "description": "Certain dis invol lymphoretic tis and reticulohistiocyt sys | Haemophagocytic syndrome, infection-associated", "attributes": null }, { "code": "D76.3", "description": "Certain dis invol lymphoretic tis and reticulohistiocyt sys | Other histiocytosis syndromes", "attributes": null }, { "code": "D77", "description": "Other disorders of blood and blood-forming organs in ", "attributes": null }, { "code": "D77.X", "description": "Other disorders of blood and blood-forming organs in | Other disorders of blood and blood-forming organs in dis CE", "attributes": null }, { "code": "D80", "description": "Immunodeficiency with predominantly antibody defects ", "attributes": null }, { "code": "D80.0", "description": "Immunodeficiency with predominantly antibody defects | Hereditary hypogammaglobulinaemia", "attributes": null }, { "code": "D80.1", "description": "Immunodeficiency with predominantly antibody defects | Nonfamilial hypogammaglobulinaemia", "attributes": null }, { "code": "D80.2", "description": "Immunodeficiency with predominantly antibody defects | Selective deficiency of immunoglobulin A [IgA]", "attributes": null }, { "code": "D80.3", "description": "Immunodeficiency with predominantly antibody defects | Selective deficiency of immunoglobulin G [IgG] subclasses", "attributes": null }, { "code": "D80.4", "description": "Immunodeficiency with predominantly antibody defects | Selective deficiency of immunoglobulin M [IgM]", "attributes": null }, { "code": "D80.5", "description": "Immunodeficiency with predominantly antibody defects | immunodefiency with increased immunoglobulin M [IgM]", "attributes": null }, { "code": "D80.6", "description": "Immunodeficiency with predominantly antibody defects | Antibod def with near-norm imunoglob/hyperimmunoglobulinaem", "attributes": null }, { "code": "D80.7", "description": "Immunodeficiency with predominantly antibody defects | Transient hypogammaglobulinaemia of infancy", "attributes": null }, { "code": "D80.8", "description": "Immunodeficiency with predominantly antibody defects | Other immunodefiencies with predominantly antibody defects", "attributes": null }, { "code": "D80.9", "description": "Immunodeficiency with predominantly antibody defects | immunodefiency with predominantly antibody defects,unspec", "attributes": null }, { "code": "D81", "description": "Combined immunodeficiencies ", "attributes": null }, { "code": "D81.0", "description": "Combined immunodeficiencies | Severe combined immunodefiency with reticular dysgenesis", "attributes": null }, { "code": "D81.1", "description": "Combined immunodeficiencies | Severe combined immunodef with low T- and B-cell numbers", "attributes": null }, { "code": "D81.2", "description": "Combined immunodeficiencies | Severe combined immunodef with low or normal B-cell numbers", "attributes": null }, { "code": "D81.3", "description": "Combined immunodeficiencies | Adenosine deaminase [ADA] deficiency", "attributes": null }, { "code": "D81.4", "description": "Combined immunodeficiencies | Nezelof's syndrome", "attributes": null }, { "code": "D81.5", "description": "Combined immunodeficiencies | Purine nucleoside phosphorylase [PNP] deficiency", "attributes": null }, { "code": "D81.6", "description": "Combined immunodeficiencies | Major histocompatibility complex class I deficiency", "attributes": null }, { "code": "D81.7", "description": "Combined immunodeficiencies | Major histocompatibility complex class II deficiency", "attributes": null }, { "code": "D81.8", "description": "Combined immunodeficiencies | Other combined immunodefiencies", "attributes": null }, { "code": "D81.9", "description": "Combined immunodeficiencies | Combined immunodefiency, unspecified", "attributes": null }, { "code": "D82", "description": "Immunodeficiency associated with other major defects ", "attributes": null }, { "code": "D82.0", "description": "Immunodeficiency associated with other major defects | Wiskott-Aldrich syndrome", "attributes": null }, { "code": "D82.1", "description": "Immunodeficiency associated with other major defects | Di George's syndrome", "attributes": null }, { "code": "D82.2", "description": "Immunodeficiency associated with other major defects | immunodefiency with short-limbed stature", "attributes": null }, { "code": "D82.3", "description": "Immunodeficiency associated with other major defects | Immunodef follow hereditary defect respon Epstein-Barr vir", "attributes": null }, { "code": "D82.4", "description": "Immunodeficiency associated with other major defects | Hyperimmunoglobulin E [IgE] syndrome", "attributes": null }, { "code": "D82.8", "description": "Immunodeficiency associated with other major defects | immunodefiency assoc with other specified major defects", "attributes": null }, { "code": "D82.9", "description": "Immunodeficiency associated with other major defects | immunodefiency associated with major defect, unspecified", "attributes": null }, { "code": "D83", "description": "Common variable immunodeficiency ", "attributes": null }, { "code": "D83.0", "description": "Common variable immunodeficiency | Com var immunodef with predom abn B-cell numb and funct", "attributes": null }, { "code": "D83.1", "description": "Common variable immunodeficiency | Common var immunodef predom immunoregulatory T-cell disord", "attributes": null }, { "code": "D83.2", "description": "Common variable immunodeficiency | Common variable immunodef autoantibodies to B- or T-cells", "attributes": null }, { "code": "D83.8", "description": "Common variable immunodeficiency | Other common variable immunodefiencies", "attributes": null }, { "code": "D83.9", "description": "Common variable immunodeficiency | Common variable immunodefiency, unspecified", "attributes": null }, { "code": "D84", "description": "Other immunodeficiencies ", "attributes": null }, { "code": "D84.0", "description": "Other immunodeficiencies | Lymphocyte function antigen-1 [LFA-1] defect", "attributes": null }, { "code": "D84.1", "description": "Other immunodeficiencies | Defects in the complement system", "attributes": null }, { "code": "D84.8", "description": "Other immunodeficiencies | Other specified immunodefiencies", "attributes": null }, { "code": "D84.9", "description": "Other immunodeficiencies | immunodefiency, unspecified", "attributes": null }, { "code": "D86", "description": "Sarcoidosis ", "attributes": null }, { "code": "D86.0", "description": "Sarcoidosis | Sarcoidosis of lung", "attributes": null }, { "code": "D86.1", "description": "Sarcoidosis | Sarcoidosis of lymph nodes", "attributes": null }, { "code": "D86.2", "description": "Sarcoidosis | Sarcoidosis of lung with sarcoidosis of lymph nodes", "attributes": null }, { "code": "D86.3", "description": "Sarcoidosis | Sarcoidosis of skin", "attributes": null }, { "code": "D86.8", "description": "Sarcoidosis | Sarcoidosis of other and combined sites", "attributes": null }, { "code": "D86.9", "description": "Sarcoidosis | Sarcoidosis, unspecified", "attributes": null }, { "code": "D89", "description": "Other disorders involving the immune mechanism NEC ", "attributes": null }, { "code": "D89.0", "description": "Other disorders involving the immune mechanism NEC | Polyclonal hypergammaglobulinaemia", "attributes": null }, { "code": "D89.1", "description": "Other disorders involving the immune mechanism NEC | Cryoglobulinaemia", "attributes": null }, { "code": "D89.2", "description": "Other disorders involving the immune mechanism NEC | Hypergammaglobulinaemia, unspecified", "attributes": null }, { "code": "D89.8", "description": "Other disorders involving the immune mechanism NEC | Oth specified disorders involving the immune mechanism NEC", "attributes": null }, { "code": "D89.9", "description": "Other disorders involving the immune mechanism NEC | Disorder involving the immune mechanism, unspecified", "attributes": null } ] } ], "status": 1, "doi": null, "is_deleted": false, "publish_status": 2, "owner": "lees", "template": { "id": 1, "name": "Clinical-Coded Phenotype", "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.", "version_id": 1 }, "versions": [ { "version_id": 4101, "version_name": "Death by diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (natural cause)", "version_date": "2025-07-02T10:40:47.837599Z", "is_published": true, "is_latest": true }, { "version_id": 2979, "version_name": "Death by diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (natural cause)", "version_date": "2023-11-13T20:05:40.073452Z", "is_published": true, "is_latest": false } ] } ]