[
  {
    "phenotype_id": "PH1690",
    "phenotype_version_id": 3620,
    "name": "Chronic paediatric conditions: Asthma",
    "definition": "This code list is part of a set of harmonised code lists to identify chronic paediatricconditions\nacross primary and secondary care datasets across the UK.\n\nPublished code lists for ICD-10, Read v2 and SNOMED combined as below:\n\n- ICD-10 asthma diagnoses as per Hardelid 2014\n- Read v2 asthma code list: [https://phenotypes.healthdatagateway.org/phenotypes/PH680/version/1360/detail/](https://phenotypes.healthdatagateway.org/phenotypes/PH680/version/1360/detail/)   \n- SNOMED asthma code list: [https://www.opencodelists.org/codelist/primis-covid19-vacc-uptake/ast/v.1.5.3/#full-list](https://www.opencodelists.org/codelist/primis-covid19-vacc-uptake/ast/v.1.5.3/#full-list)\n\n### Methods\n\nChronic paediatric conditions were defined as health problems requiring medical follow-upfor\nmore than 12 months in 50% or more of cases. Code lists were produced by mappingexisting\nICD-10 codes for chronic paediatric conditions to SNOMED and Read v2 codesusing the\nCALIBER R package, with review by paediatric sub-specialists.\n\nAn established ICD-10 code list of chronic paediatric conditions (Hardelid 2014)was\nused as the basis for the new lists.1  Chronic paediatric conditions were definedas\nany health problem requiring medical follow-up (hospital admission, outpatientfollow\nup or use of support services such as physiotherapy) for more than 12 monthsin 50%\nor more of cases.[1]  A Chronic Paediatric Conditions Committee of paediatricsub-specialists\nwas established. The original ICD-10 list was screened by two paediatriciansand acute\nconditions removed, with disagreements resolved by a third paediatrician.Conditions\nwhich were likely acute and would not fulfil our chronic disease definitionwere excluded,\nincluding skeletal injuries and self-harm. Drug-induced conditionswere excluded as\nchronicity was not known. Infections other than human immunodeficiencyvirus (HIV),\nhepatitis B or C, or congenital infections (syphilis / toxoplasmosis/ rubella / herpes\nsimplex virus / cytomegalovirus) were excluded. Chronic sequelaeof infections were\nretained.\n\nPublished code lists were then identified for Read v2 and SNOMED codes for well-characterisedconditions\nincluding asthma, diabetes, cystic fibrosis and cancer. The remainingICD-10 codes\nwere mapped to SNOMED and Read v2 codes using the CALIBER R packageand Technology\nReference Update Distribution NHS Data Migration tables [2] to producenew code lists\nsuitable for primary care data. These resulting code lists were screenedby two sub-specialists\nto ensure conditions were chronic and in the correct subgroupwith disagreements resolved\nby a third clinician.\n\n### References:\n\n1. Hardelid P, Dattani N, Gilbert R. Estimating the prevalence of chronic conditions in children who die in England, Scotland and Wales: a data linkage cohort study. BMJ Open 2014; 4: e005331.\n2. CALIBER codelists-package: Generate ICD, Read and OPCS codelists in CALIBER codelists: Generate ICD10, Read and OPCS codelists, [https://rdrr.io/rforge/CALIBERcodelists/man/CALIBERcodelists-package.html](https://rdrr.io/rforge/CALIBERcodelists/man/CALIBERcodelists-package.html) (accessed 19 October 2022).\n\n",
    "implementation": "We have considered conditions to be active if they had been coded for in the precedingfive\nyears. In addition, conditions from the following subgroups were consideredto be\npermanent, therefore active if coded for at any time: metabolic, diabetes,cystic\nfibrosis, transplant, receiving palliative care, other congenital multisystemsyndromes\nand chromosomal abnormalities, immunological and cerebral palsy / paralysis(a subgroup\nof \"Other neurology\" code list).\n",
    "publications": [],
    "validation": "",
    "citation_requirements": "To our knowledge, these are the first set of harmonised code lists for chronic paediatricconditions\nthat span commonly used primary and secondary care coding systems in theUK. We hope\nthey will prove a valuable resource for the paediatric research communityand welcome\nsuggestions for further development ([Olivia.Swann@ed.ac.uk](mailto:Olivia.Swann@ed.ac.uk)).\n",
    "created": "2025-01-17T21:04:11.438003Z",
    "author": "Swann OV, Williams TC, Fraser LK, Farrell J, Parker M, Kennedy J, Seabourne M, Brophy S, Harrison EM, Docherty AB, Pollock L",
    "collections": [
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": null,
    "world_access": 2,
    "updated": "2025-01-19T15:45:59.091279Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Disease or syndrome",
        "value": "2"
      }
    ],
    "ontology": [
      {
        "name": "Paediatrics",
        "value": 842203
      },
      {
        "name": "Paediatric and Perinatal Pathology",
        "value": 842275
      }
    ],
    "phenoflowid": "",
    "data_sources": [
      {
        "name": "Hospital Episode Statistics Admitted Patient Care",
        "value": 2,
        "uid": "6599230a-df54-4615-937c-d724d239491f",
        "url": "https://healthdatagateway.org/en/dataset/875",
        "datasource_id": 875
      },
      {
        "name": "OpenSAFELY SNOMED CT",
        "value": 36,
        "datasource_id": 36
      },
      {
        "name": "Patient Episode Dataset for Wales (PEDW)",
        "value": 40,
        "uid": "4c33a5d2-164c-41d7-9797-dc2b008cc852",
        "url": "https://healthdatagateway.org/en/dataset/318",
        "datasource_id": 318
      },
      {
        "name": "Welsh Longitudinal General Practice Dataset (WLGP) - Welsh Primary Care",
        "value": 502,
        "uid": "33fc3ffd-aa4c-4a16-a32f-0c900aaea3d2",
        "url": "https://healthdatagateway.org/en/dataset/355",
        "datasource_id": 355
      }
    ],
    "coding_system": [
      {
        "name": "SNOMED  CT codes",
        "value": 9
      },
      {
        "name": "ICD10 codes",
        "value": 4
      },
      {
        "name": "Read codes v2",
        "value": 5
      }
    ],
    "event_date_range": "2021/01/01 - 2021/01/01",
    "concept_information": [
      {
        "concept_id": 4041,
        "concept_version_id": 11396,
        "concept_name": "Asthma (ICD-10)",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH1690",
        "phenotype_version_id": 3620,
        "phenotype_name": "Chronic paediatric conditions: Asthma",
        "code_attribute_header": null,
        "codes": [
          {
            "code": "J45",
            "description": "Asthma",
            "attributes": null
          },
          {
            "code": "J450",
            "description": "Predominantly allergic asthma",
            "attributes": null
          },
          {
            "code": "J451",
            "description": "Nonallergic asthma",
            "attributes": null
          },
          {
            "code": "J458",
            "description": "Mixed asthma",
            "attributes": null
          },
          {
            "code": "J459",
            "description": "Asthma, unspecified",
            "attributes": null
          },
          {
            "code": "J46",
            "description": "Status asthmaticus",
            "attributes": null
          }
        ]
      },
      {
        "concept_id": 4042,
        "concept_version_id": 11397,
        "concept_name": "Asthma (Read v2)",
        "coding_system": {
          "id": 5,
          "name": "Read codes v2",
          "description": "Read codes v2"
        },
        "phenotype_id": "PH1690",
        "phenotype_version_id": 3620,
        "phenotype_name": "Chronic paediatric conditions: Asthma",
        "code_attribute_header": null,
        "codes": [
          {
            "code": "H312000",
            "description": "Chronic asthmatic bronchitis",
            "attributes": null
          },
          {
            "code": "H312011",
            "description": "Chronic wheezy bronchitis",
            "attributes": null
          },
          {
            "code": "H33..00",
            "description": "Asthma",
            "attributes": null
          },
          {
            "code": "H330.00",
            "description": "Extrinsic (atopic) asthma",
            "attributes": null
          },
          {
            "code": "H330000",
            "description": "Extrinsic asthma without status asthmaticus",
            "attributes": null
          },
          {
            "code": "H330011",
            "description": "Hay fever with asthma",
            "attributes": null
          },
          {
            "code": "H330100",
            "description": "Extrinsic asthma with status asthmaticus",
            "attributes": null
          },
          {
            "code": "H330.11",
            "description": "Allergic asthma",
            "attributes": null
          },
          {
            "code": "H330111",
            "description": "Extrinsic asthma with asthma attack",
            "attributes": null
          },
          {
            "code": "H330.12",
            "description": "Childhood asthma",
            "attributes": null
          },
          {
            "code": "H330.13",
            "description": "Hay fever with asthma",
            "attributes": null
          },
          {
            "code": "H330.14",
            "description": "Pollen asthma",
            "attributes": null
          },
          {
            "code": "H330z00",
            "description": "Extrinsic asthma NOS",
            "attributes": null
          },
          {
            "code": "H331.00",
            "description": "Intrinsic asthma",
            "attributes": null
          },
          {
            "code": "H331000",
            "description": "Intrinsic asthma without status asthmaticus",
            "attributes": null
          },
          {
            "code": "H33..11",
            "description": "Bronchial asthma",
            "attributes": null
          },
          {
            "code": "H331100",
            "description": "Intrinsic asthma with status asthmaticus",
            "attributes": null
          },
          {
            "code": "H331.11",
            "description": "Late onset asthma",
            "attributes": null
          },
          {
            "code": "H331111",
            "description": "Intrinsic asthma with asthma attack",
            "attributes": null
          },
          {
            "code": "H331z00",
            "description": "Intrinsic asthma NOS",
            "attributes": null
          },
          {
            "code": "H332.00",
            "description": "Mixed asthma",
            "attributes": null
          },
          {
            "code": "H333.00",
            "description": "Acute exacerbation of asthma",
            "attributes": null
          },
          {
            "code": "H334.00",
            "description": "Brittle asthma",
            "attributes": null
          },
          {
            "code": "H33z.00",
            "description": "Asthma unspecified",
            "attributes": null
          },
          {
            "code": "H33z000",
            "description": "Status asthmaticus NOS",
            "attributes": null
          },
          {
            "code": "H33z011",
            "description": "Severe asthma attack",
            "attributes": null
          },
          {
            "code": "H33z100",
            "description": "Asthma attack",
            "attributes": null
          },
          {
            "code": "H33z111",
            "description": "Asthma attack NOS",
            "attributes": null
          },
          {
            "code": "H33z200",
            "description": "Late-onset asthma",
            "attributes": null
          },
          {
            "code": "H33zz00",
            "description": "Asthma NOS",
            "attributes": null
          },
          {
            "code": "H33zz11",
            "description": "Exercise induced asthma",
            "attributes": null
          },
          {
            "code": "H33zz12",
            "description": "Allergic asthma NEC",
            "attributes": null
          },
          {
            "code": "H47y000",
            "description": "Detergent asthma",
            "attributes": null
          }
        ]
      },
      {
        "concept_id": 4043,
        "concept_version_id": 11398,
        "concept_name": "Asthma (SNOMED-CT)",
        "coding_system": {
          "id": 9,
          "name": "SNOMED  CT codes",
          "description": "SNOMED CT codes"
        },
        "phenotype_id": "PH1690",
        "phenotype_version_id": 3620,
        "phenotype_name": "Chronic paediatric conditions: Asthma",
        "code_attribute_header": null,
        "codes": [
          {
            "code": "103781000119103",
            "description": "Allergic bronchopulmonary mycosis",
            "attributes": null
          },
          {
            "code": "10674711000119105",
            "description": "Acute severe exacerbation of asthma co-occurrent with allergic rhinitis",
            "attributes": null
          },
          {
            "code": "10674991000119104",
            "description": "Intermittent allergic asthma",
            "attributes": null
          },
          {
            "code": "10675391000119101",
            "description": "Severe controlled persistent asthma",
            "attributes": null
          },
          {
            "code": "10675431000119106",
            "description": "Severe persistent allergic asthma",
            "attributes": null
          },
          {
            "code": "10675471000119109",
            "description": "Acute severe exacerbation of severe persistent allergic asthma",
            "attributes": null
          },
          {
            "code": "10675551000119104",
            "description": "Acute severe exacerbation of severe persistent asthma co-occurrent with allergic rhinitis",
            "attributes": null
          },
          {
            "code": "10675751000119107",
            "description": "Severe uncontrolled persistent asthma",
            "attributes": null
          },
          {
            "code": "10675871000119106",
            "description": "Mild persistent allergic asthma",
            "attributes": null
          },
          {
            "code": "10675911000119109",
            "description": "Acute severe exacerbation of mild persistent allergic asthma",
            "attributes": null
          },
          {
            "code": "10675991000119100",
            "description": "Acute severe exacerbation of mild persistent allergic asthma co-occurrent with allergic rhinitis",
            "attributes": null
          },
          {
            "code": "10676391000119108",
            "description": "Moderate persistent allergic asthma",
            "attributes": null
          },
          {
            "code": "10676431000119103",
            "description": "Acute severe exacerbation of moderate persistent allergic asthma",
            "attributes": null
          },
          {
            "code": "10676511000119109",
            "description": "Acute severe exacerbation of moderate persistent asthma co-occurrent with allergic rhinitis",
            "attributes": null
          },
          {
            "code": "10692681000119108",
            "description": "Aspirin exacerbated respiratory disease",
            "attributes": null
          },
          {
            "code": "10692721000119102",
            "description": "Chronic obstructive asthma co-occurrent with acute exacerbation of asthma",
            "attributes": null
          },
          {
            "code": "10692761000119107",
            "description": "Asthma-chronic obstructive pulmonary disease overlap syndrome",
            "attributes": null
          },
          {
            "code": "10742121000119104",
            "description": "Asthma in mother complicating childbirth",
            "attributes": null
          },
          {
            "code": "1086701000000102",
            "description": "Life threatening acute exacerbation of allergic asthma",
            "attributes": null
          },
          {
            "code": "1086711000000100",
            "description": "Life threatening acute exacerbation of intrinsic asthma",
            "attributes": null
          },
          {
            "code": "1103911000000103",
            "description": "Severe asthma with fungal sensitisation",
            "attributes": null
          },
          {
            "code": "11641008",
            "description": "Millers' asthma",
            "attributes": null
          },
          {
            "code": "12428000",
            "description": "Intrinsic asthma without status asthmaticus",
            "attributes": null
          },
          {
            "code": "124991000119109",
            "description": "Severe persistent asthma co-occurrent with allergic rhinitis",
            "attributes": null
          },
          {
            "code": "125001000119103",
            "description": "Moderate persistent asthma co-occurrent with allergic rhinitis",
            "attributes": null
          },
          {
            "code": "125011000119100",
            "description": "Mild persistent asthma co-occurrent with allergic rhinitis",
            "attributes": null
          },
          {
            "code": "125021000119107",
            "description": "Intermittent asthma co-occurrent with allergic rhinitis",
            "attributes": null
          },
          {
            "code": "135171000119106",
            "description": "Acute exacerbation of moderate persistent asthma",
            "attributes": null
          },
          {
            "code": "135181000119109",
            "description": "Acute exacerbation of mild persistent asthma",
            "attributes": null
          },
          {
            "code": "16584951000119101",
            "description": "Oral steroid-dependent asthma",
            "attributes": null
          },
          {
            "code": "1741000119102",
            "description": "Intermittent asthma uncontrolled",
            "attributes": null
          },
          {
            "code": "1751000119100",
            "description": "Acute exacerbation of chronic obstructive airways disease with asthma",
            "attributes": null
          },
          {
            "code": "18041002",
            "description": "Printers' asthma",
            "attributes": null
          },
          {
            "code": "195949008",
            "description": "Chronic asthmatic bronchitis",
            "attributes": null
          },
          {
            "code": "195967001",
            "description": "Asthma",
            "attributes": null
          },
          {
            "code": "195977004",
            "description": "Mixed asthma",
            "attributes": null
          },
          {
            "code": "19849005",
            "description": "Meat-wrappers' asthma",
            "attributes": null
          },
          {
            "code": "225057002",
            "description": "Brittle asthma",
            "attributes": null
          },
          {
            "code": "233678006",
            "description": "Childhood asthma",
            "attributes": null
          },
          {
            "code": "233679003",
            "description": "Late onset asthma",
            "attributes": null
          },
          {
            "code": "233683003",
            "description": "Hay fever with asthma",
            "attributes": null
          },
          {
            "code": "233687002",
            "description": "Colophony asthma",
            "attributes": null
          },
          {
            "code": "233688007",
            "description": "Sulfite-induced asthma",
            "attributes": null
          },
          {
            "code": "2360001000004109",
            "description": "Steroid dependent asthma",
            "attributes": null
          },
          {
            "code": "266361008",
            "description": "Non-allergic asthma",
            "attributes": null
          },
          {
            "code": "281239006",
            "description": "Exacerbation of asthma",
            "attributes": null
          },
          {
            "code": "304527002",
            "description": "Acute asthma",
            "attributes": null
          },
          {
            "code": "31387002",
            "description": "Exercise-induced asthma",
            "attributes": null
          },
          {
            "code": "34015007",
            "description": "Bakers' asthma",
            "attributes": null
          },
          {
            "code": "370218001",
            "description": "Mild asthma",
            "attributes": null
          },
          {
            "code": "370219009",
            "description": "Moderate asthma",
            "attributes": null
          },
          {
            "code": "370220003",
            "description": "Occasional asthma",
            "attributes": null
          },
          {
            "code": "370221004",
            "description": "Severe asthma",
            "attributes": null
          },
          {
            "code": "37981002",
            "description": "Allergic bronchopulmonary aspergillosis",
            "attributes": null
          },
          {
            "code": "389145006",
            "description": "Allergic asthma",
            "attributes": null
          },
          {
            "code": "401000119107",
            "description": "Asthma with irreversible airway obstruction",
            "attributes": null
          },
          {
            "code": "404804003",
            "description": "Platinum asthma",
            "attributes": null
          },
          {
            "code": "404806001",
            "description": "Cheese-makers' asthma",
            "attributes": null
          },
          {
            "code": "404808000",
            "description": "Isocyanate induced asthma",
            "attributes": null
          },
          {
            "code": "405944004",
            "description": "Asthmatic bronchitis",
            "attributes": null
          },
          {
            "code": "407674008",
            "description": "Aspirin-induced asthma",
            "attributes": null
          },
          {
            "code": "409663006",
            "description": "Cough variant asthma",
            "attributes": null
          },
          {
            "code": "41553006",
            "description": "Detergent asthma",
            "attributes": null
          },
          {
            "code": "418395004",
            "description": "Tea-makers' asthma",
            "attributes": null
          },
          {
            "code": "423889005",
            "description": "Non-immunoglobulin E mediated allergic asthma",
            "attributes": null
          },
          {
            "code": "424199006",
            "description": "Substance induced asthma",
            "attributes": null
          },
          {
            "code": "424643009",
            "description": "Immunoglobulin E-mediated allergic asthma",
            "attributes": null
          },
          {
            "code": "425969006",
            "description": "Exacerbation of intermittent asthma",
            "attributes": null
          },
          {
            "code": "426656000",
            "description": "Severe persistent asthma",
            "attributes": null
          },
          {
            "code": "426979002",
            "description": "Mild persistent asthma",
            "attributes": null
          },
          {
            "code": "427295004",
            "description": "Moderate persistent asthma",
            "attributes": null
          },
          {
            "code": "427603009",
            "description": "Intermittent asthma",
            "attributes": null
          },
          {
            "code": "427679007",
            "description": "Mild intermittent asthma",
            "attributes": null
          },
          {
            "code": "442025000",
            "description": "Acute exacerbation of chronic asthmatic bronchitis",
            "attributes": null
          },
          {
            "code": "445427006",
            "description": "Seasonal asthma",
            "attributes": null
          },
          {
            "code": "55570000",
            "description": "Asthma without status asthmaticus",
            "attributes": null
          },
          {
            "code": "56968009",
            "description": "Asthma caused by wood dust",
            "attributes": null
          },
          {
            "code": "57607007",
            "description": "Occupational asthma",
            "attributes": null
          },
          {
            "code": "59786004",
            "description": "Weavers' cough",
            "attributes": null
          },
          {
            "code": "63088003",
            "description": "Allergic asthma without status asthmaticus",
            "attributes": null
          },
          {
            "code": "703953004",
            "description": "Allergic asthma caused by Dermatophagoides pteronyssinus",
            "attributes": null
          },
          {
            "code": "703954005",
            "description": "Allergic asthma caused by Dermatophagoides farinae",
            "attributes": null
          },
          {
            "code": "707444001",
            "description": "Uncomplicated asthma",
            "attributes": null
          },
          {
            "code": "707445000",
            "description": "Exacerbation of mild persistent asthma",
            "attributes": null
          },
          {
            "code": "707446004",
            "description": "Exacerbation of moderate persistent asthma",
            "attributes": null
          },
          {
            "code": "707447008",
            "description": "Exacerbation of severe persistent asthma",
            "attributes": null
          },
          {
            "code": "707511009",
            "description": "Uncomplicated mild persistent asthma",
            "attributes": null
          },
          {
            "code": "707512002",
            "description": "Uncomplicated moderate persistent asthma",
            "attributes": null
          },
          {
            "code": "707513007",
            "description": "Uncomplicated severe persistent asthma",
            "attributes": null
          },
          {
            "code": "707979007",
            "description": "Acute severe exacerbation of severe persistent asthma",
            "attributes": null
          },
          {
            "code": "707980005",
            "description": "Acute severe exacerbation of moderate persistent asthma",
            "attributes": null
          },
          {
            "code": "707981009",
            "description": "Acute severe exacerbation of mild persistent asthma",
            "attributes": null
          },
          {
            "code": "708038006",
            "description": "Acute exacerbation of asthma",
            "attributes": null
          },
          {
            "code": "708090002",
            "description": "Acute severe exacerbation of asthma",
            "attributes": null
          },
          {
            "code": "708093000",
            "description": "Acute exacerbation of immunoglobulin E-mediated allergic asthma",
            "attributes": null
          },
          {
            "code": "708094006",
            "description": "Acute exacerbation of intrinsic asthma",
            "attributes": null
          },
          {
            "code": "708095007",
            "description": "Acute severe exacerbation of immunoglobin E-mediated allergic asthma",
            "attributes": null
          },
          {
            "code": "708096008",
            "description": "Acute severe exacerbation of intrinsic asthma",
            "attributes": null
          },
          {
            "code": "72301000119103",
            "description": "Asthma in pregnancy",
            "attributes": null
          },
          {
            "code": "733858005",
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