[
  {
    "phenotype_id": "PH1699",
    "phenotype_version_id": 3626,
    "name": "Chronic paediatric conditions: Epilepsy",
    "definition": "This code list is part of a set of harmonised code lists to identify chronic paediatric\nconditions across primary and secondary care datasets across the UK.\n\n- ICD-10 epilepsy conditions as per Hardelid 2014, mapped to SNOMED and Read v2 using CALIBER.\n- Excludes febrile seizures.\n- Includes epilepsy syndromes and afebrile seizures.\n\n### Methods\n\nChronic paediatric conditions were defined as health problems requiring medical follow-up\nfor more than 12 months in 50% or more of cases. Code lists were produced by mapping\nexisting ICD-10 codes for chronic paediatric conditions to SNOMED and Read v2 codes\nusing the CALIBER R package, with review by paediatric sub-specialists.\n\nAn established ICD-10 code list of chronic paediatric conditions (Hardelid 2014)\nwas used as the basis for the new lists.1  Chronic paediatric conditions were defined\nas any health problem requiring medical follow-up (hospital admission, outpatient\nfollow up or use of support services such as physiotherapy) for more than 12 months\nin 50% or more of cases.[1]  A Chronic Paediatric Conditions Committee of paediatric\nsub-specialists was established. The original ICD-10 list was screened by two paediatricians\nand acute conditions removed, with disagreements resolved by a third paediatrician.\nConditions which were likely acute and would not fulfil our chronic disease definition\nwere excluded, including skeletal injuries and self-harm. Drug-induced conditions\nwere excluded as chronicity was not known. Infections other than human immunodeficiency\nvirus (HIV), hepatitis B or C, or congenital infections (syphilis / toxoplasmosis\n/ rubella / herpes simplex virus / cytomegalovirus) were excluded. Chronic sequelae\nof infections were retained.\n\nPublished code lists were then identified for Read v2 and SNOMED codes for well-characterised\nconditions including asthma, diabetes, cystic fibrosis and cancer. The remaining\nICD-10 codes were mapped to SNOMED and Read v2 codes using the CALIBER R package\nand Technology Reference Update Distribution NHS Data Migration tables [2] to produce\nnew code lists suitable for primary care data. These resulting code lists were screened\nby two sub-specialists to ensure conditions were chronic and in the correct subgroup\nwith disagreements resolved by a third clinician.\n\n### References:\n\n1. Hardelid P, Dattani N, Gilbert R. Estimating the prevalence of chronic conditions in children who die in England, Scotland and Wales: a data linkage cohort study. BMJ Open 2014; 4: e005331.\n2. CALIBER codelists-package: Generate ICD, Read and OPCS codelists in CALIBER codelists: Generate ICD10, Read and OPCS codelists, [https://rdrr.io/rforge/CALIBERcodelists/man/CALIBERcodelists-package.html](https://rdrr.io/rforge/CALIBERcodelists/man/CALIBERcodelists-package.html) (accessed 19 October 2022).\n\n",
    "implementation": "We have considered conditions to be active if they had been coded for in the preceding\nfive years. In addition, conditions from the following subgroups were considered\nto be permanent, therefore active if coded for at any time: metabolic, diabetes,\ncystic fibrosis, transplant, receiving palliative care, other congenital multisystem\nsyndromes and chromosomal abnormalities, immunological and cerebral palsy / paralysis\n(a subgroup of \"Other neurology\" code list).\n",
    "publications": [],
    "validation": "",
    "citation_requirements": "To our knowledge, these are the first set of harmonised code lists for chronic paediatric\nconditions that span commonly used primary and secondary care coding systems in the\nUK. We hope they will prove a valuable resource for the paediatric research community\nand welcome suggestions for further development ([Olivia.Swann@ed.ac.uk](mailto:Olivia.Swann@ed.ac.uk)).\n",
    "created": "2025-01-18T19:47:52.302301Z",
    "author": "Swann OV, Williams TC, Fraser LK, Farrell J, Parker M, Kennedy J, Seabourne M, Brophy S, Harrison EM, Docherty AB, Pollock L",
    "collections": [
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": null,
    "world_access": 2,
    "updated": "2025-01-19T15:59:36.041744Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Disease or syndrome",
        "value": "2"
      }
    ],
    "ontology": [
      {
        "name": "Paediatrics",
        "value": 842203
      },
      {
        "name": "Paediatric and Perinatal Pathology",
        "value": 842275
      }
    ],
    "phenoflowid": "",
    "data_sources": [
      {
        "name": "Hospital Episode Statistics Admitted Patient Care",
        "value": 2,
        "uid": "6599230a-df54-4615-937c-d724d239491f",
        "url": "https://healthdatagateway.org/en/dataset/875",
        "datasource_id": 875
      },
      {
        "name": "OpenSAFELY SNOMED CT",
        "value": 36,
        "datasource_id": 36
      },
      {
        "name": "Patient Episode Dataset for Wales (PEDW)",
        "value": 40,
        "uid": "4c33a5d2-164c-41d7-9797-dc2b008cc852",
        "url": "https://healthdatagateway.org/en/dataset/318",
        "datasource_id": 318
      },
      {
        "name": "Welsh Longitudinal General Practice Dataset (WLGP) - Welsh Primary Care",
        "value": 502,
        "uid": "33fc3ffd-aa4c-4a16-a32f-0c900aaea3d2",
        "url": "https://healthdatagateway.org/en/dataset/355",
        "datasource_id": 355
      }
    ],
    "coding_system": [
      {
        "name": "SNOMED  CT codes",
        "value": 9
      },
      {
        "name": "ICD10 codes",
        "value": 4
      },
      {
        "name": "Read codes v2",
        "value": 5
      }
    ],
    "event_date_range": "2021/01/01 - 2021/01/01",
    "concept_information": [
      {
        "concept_id": 4110,
        "concept_version_id": 11465,
        "concept_name": "Epilepsy (ICD-10)",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH1699",
        "phenotype_version_id": 3626,
        "phenotype_name": "Chronic paediatric conditions: Epilepsy",
        "code_attribute_header": null,
        "codes": [
          {
            "code": "G40",
            "description": "Epilepsy",
            "attributes": null
          },
          {
            "code": "G400",
            "description": "Localization-related (focal)(partial) idiopathic epilepsy and epileptic syndromes with seizures of localized onset",
            "attributes": null
          },
          {
            "code": "G401",
            "description": "Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures",
            "attributes": null
          },
          {
            "code": "G402",
            "description": "Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures",
            "attributes": null
          },
          {
            "code": "G403",
            "description": "Generalized idiopathic epilepsy and epileptic syndromes",
            "attributes": null
          },
          {
            "code": "G404",
            "description": "Other generalized epilepsy and epileptic syndromes",
            "attributes": null
          },
          {
            "code": "G405",
            "description": "Special epileptic syndromes",
            "attributes": null
          },
          {
            "code": "G406",
            "description": "Grand mal seizures, unspecified (with or without petit mal)",
            "attributes": null
          },
          {
            "code": "G407",
            "description": "Petit mal, unspecified, without grand mal seizures",
            "attributes": null
          },
          {
            "code": "G408",
            "description": "Other epilepsy",
            "attributes": null
          },
          {
            "code": "G409",
            "description": "Epilepsy, unspecified",
            "attributes": null
          },
          {
            "code": "G41",
            "description": "Status epilepticus",
            "attributes": null
          },
          {
            "code": "G410",
            "description": "Grand mal status epilepticus",
            "attributes": null
          },
          {
            "code": "G411",
            "description": "Petit mal status epilepticus",
            "attributes": null
          },
          {
            "code": "G412",
            "description": "Complex partial status epilepticus",
            "attributes": null
          },
          {
            "code": "G418",
            "description": "Other status epilepticus",
            "attributes": null
          },
          {
            "code": "G419",
            "description": "Status epilepticus, unspecified",
            "attributes": null
          }
        ]
      },
      {
        "concept_id": 4111,
        "concept_version_id": 11466,
        "concept_name": "Epilepsy (Read v2)",
        "coding_system": {
          "id": 5,
          "name": "Read codes v2",
          "description": "Read codes v2"
        },
        "phenotype_id": "PH1699",
        "phenotype_version_id": 3626,
        "phenotype_name": "Chronic paediatric conditions: Epilepsy",
        "code_attribute_header": null,
        "codes": [
          {
            "code": "2828",
            "description": "Absence seizure",
            "attributes": null
          },
          {
            "code": "667B.00",
            "description": "Nocturnal epilepsy",
            "attributes": null
          },
          {
            "code": "F132100",
            "description": "Progressive myoclonic epilepsy",
            "attributes": null
          },
          {
            "code": "F132111",
            "description": "Unverricht - Lundborg disease",
            "attributes": null
          },
          {
            "code": "F132200",
            "description": "Myoclonic encephalopathy",
            "attributes": null
          },
          {
            "code": "F132z11",
            "description": "Unverricht - Lundborg disease",
            "attributes": null
          },
          {
            "code": "F132z12",
            "description": "Myoclonic seizure",
            "attributes": null
          },
          {
            "code": "F25..00",
            "description": "Epilepsy",
            "attributes": null
          },
          {
            "code": "F250.00",
            "description": "Generalised nonconvulsive epilepsy",
            "attributes": null
          },
          {
            "code": "F250100",
            "description": "Pykno-epilepsy",
            "attributes": null
          },
          {
            "code": "F250200",
            "description": "Epileptic seizures - atonic",
            "attributes": null
          },
          {
            "code": "F250300",
            "description": "Epileptic seizures - akinetic",
            "attributes": null
          },
          {
            "code": "F250400",
            "description": "Juvenile absence epilepsy",
            "attributes": null
          },
          {
            "code": "F250500",
            "description": "Lennox-Gastaut syndrome",
            "attributes": null
          },
          {
            "code": "F250y00",
            "description": "Other specified generalised nonconvulsive epilepsy",
            "attributes": null
          },
          {
            "code": "F250z00",
            "description": "Generalised nonconvulsive epilepsy NOS",
            "attributes": null
          },
          {
            "code": "F251.00",
            "description": "Generalised convulsive epilepsy",
            "attributes": null
          },
          {
            "code": "F251000",
            "description": "Grand mal (major) epilepsy",
            "attributes": null
          },
          {
            "code": "F251011",
            "description": "Tonic-clonic epilepsy",
            "attributes": null
          },
          {
            "code": "F251100",
            "description": "Neonatal myoclonic epilepsy",
            "attributes": null
          },
          {
            "code": "F251111",
            "description": "Otohara syndrome",
            "attributes": null
          },
          {
            "code": "F251200",
            "description": "Epileptic seizures - clonic",
            "attributes": null
          },
          {
            "code": "F251400",
            "description": "Epileptic seizures - tonic",
            "attributes": null
          },
          {
            "code": "F251500",
            "description": "Tonic-clonic epilepsy",
            "attributes": null
          },
          {
            "code": "F251600",
            "description": "Grand mal seizure",
            "attributes": null
          },
          {
            "code": "F251y00",
            "description": "Other specified generalised convulsive epilepsy",
            "attributes": null
          },
          {
            "code": "F251z00",
            "description": "Generalised convulsive epilepsy NOS",
            "attributes": null
          },
          {
            "code": "F252.00",
            "description": "Petit mal status",
            "attributes": null
          },
          {
            "code": "F253.00",
            "description": "Grand mal status",
            "attributes": null
          },
          {
            "code": "F253.11",
            "description": "Status epilepticus",
            "attributes": null
          },
          {
            "code": "F254.00",
            "description": "Partial epilepsy with impairment of consciousness",
            "attributes": null
          },
          {
            "code": "F254000",
            "description": "Temporal lobe epilepsy",
            "attributes": null
          },
          {
            "code": "F254100",
            "description": "Psychomotor epilepsy",
            "attributes": null
          },
          {
            "code": "F254200",
            "description": "Psychosensory epilepsy",
            "attributes": null
          },
          {
            "code": "F254300",
            "description": "Limbic system epilepsy",
            "attributes": null
          },
          {
            "code": "F254400",
            "description": "Epileptic automatism",
            "attributes": null
          },
          {
            "code": "F254500",
            "description": "Complex partial epileptic seizure",
            "attributes": null
          },
          {
            "code": "F254z00",
            "description": "Partial epilepsy with impairment of consciousness NOS",
            "attributes": null
          },
          {
            "code": "F255.00",
            "description": "Partial epilepsy without mention of impairment of consciousness",
            "attributes": null
          },
          {
            "code": "F255000",
            "description": "Jacksonian, focal or motor epilepsy",
            "attributes": null
          },
          {
            "code": "F255011",
            "description": "Focal epilepsy",
            "attributes": null
          },
          {
            "code": "F255012",
            "description": "Motor epilepsy",
            "attributes": null
          },
          {
            "code": "F255100",
            "description": "Sensory induced epilepsy",
            "attributes": null
          },
          {
            "code": "F255200",
            "description": "Somatosensory epilepsy",
            "attributes": null
          },
          {
            "code": "F255300",
            "description": "Visceral reflex epilepsy",
            "attributes": null
          },
          {
            "code": "F255311",
            "description": "Partial epilepsy with autonomic symptoms",
            "attributes": null
          },
          {
            "code": "F255400",
            "description": "Visual reflex epilepsy",
            "attributes": null
          },
          {
            "code": "F255500",
            "description": "Unilateral epilepsy",
            "attributes": null
          },
          {
            "code": "F255y00",
            "description": "Other specified partial epilepsy without mention of impairment of consciousness",
            "attributes": null
          },
          {
            "code": "F255z00",
            "description": "Partial epilepsy without mention of impairment of consciousness NOS",
            "attributes": null
          },
          {
            "code": "F256.00",
            "description": "Infantile spasms",
            "attributes": null
          },
          {
            "code": "F256000",
            "description": "Hypsarrhythmia",
            "attributes": null
          },
          {
            "code": "F256100",
            "description": "Salaam attacks",
            "attributes": null
          },
          {
            "code": "F256.11",
            "description": "Lightning spasms",
            "attributes": null
          },
          {
            "code": "F256.12",
            "description": "West syndrome",
            "attributes": null
          },
          {
            "code": "F256z00",
            "description": "Infantile spasms NOS",
            "attributes": null
          },
          {
            "code": "F257.00",
            "description": "Kojevnikov's epilepsy",
            "attributes": null
          },
          {
            "code": "F259.00",
            "description": "Early infantile epileptic encephalopathy with suppression bursts",
            "attributes": null
          },
          {
            "code": "F259.11",
            "description": "Ohtahara syndrome",
            "attributes": null
          },
          {
            "code": "F25A.00",
            "description": "Juvenile myoclonic epilepsy",
            "attributes": null
          },
          {
            "code": "F25B.00",
            "description": "Alcohol-induced epilepsy",
            "attributes": null
          },
          {
            "code": "F25C.00",
            "description": "Drug-induced epilepsy",
            "attributes": null
          },
          {
            "code": "F25D.00",
            "description": "Menstrual epilepsy",
            "attributes": null
          },
          {
            "code": "F25E.00",
            "description": "Stress-induced epilepsy",
            "attributes": null
          },
          {
            "code": "F25F.00",
            "description": "Photosensitive epilepsy",
            "attributes": null
          },
          {
            "code": "F25G.00",
            "description": "Severe myoclonic epilepsy in infancy",
            "attributes": null
          },
          {
            "code": "F25G.11",
            "description": "Dravet syndrome",
            "attributes": null
          },
          {
            "code": "F25X.00",
            "description": "Status epilepticus, unspecified",
            "attributes": null
          },
          {
            "code": "F25y.00",
            "description": "Other forms of epilepsy",
            "attributes": null
          },
          {
            "code": "F25y000",
            "description": "Cursive (running) epilepsy",
            "attributes": null
          },
          {
            "code": "F25y100",
            "description": "Gelastic epilepsy",
            "attributes": null
          },
          {
            "code": "F25y200",
            "description": "Localization-related(focal)(partial)idiopathic epilepsy and epileptic syndromes with seizures of localised onset",
            "attributes": null
          },
          {
            "code": "F25y300",
            "description": "Complex partial status epilepticus",
            "attributes": null
          },
          {
            "code": "F25y400",
            "description": "Benign Rolandic epilepsy",
            "attributes": null
          },
          {
            "code": "F25y500",
            "description": "Panayiotopoulos syndrome",
            "attributes": null
          },
          {
            "code": "F25yz00",
            "description": "Other forms of epilepsy NOS",
            "attributes": null
          },
          {
            "code": "F25z.00",
            "description": "Epilepsy NOS",
            "attributes": null
          },
          {
            "code": "F25z.11",
            "description": "Fit (in known epileptic) NOS",
            "attributes": null
          },
          {
            "code": "Fyu5000",
            "description": "[X]Other generalized epilepsy and epileptic syndromes",
            "attributes": null
          },
          {
            "code": "Fyu5100",
            "description": "[X]Other epilepsy",
            "attributes": null
          },
          {
            "code": "Fyu5200",
            "description": "[X]Other status epilepticus",
            "attributes": null
          },
          {
            "code": "Fyu5900",
            "description": "[X]Status epilepticus, unspecified",
            "attributes": null
          },
          {
            "code": "R003400",
            "description": "[D]Nocturnal seizure",
            "attributes": null
          }
        ]
      },
      {
        "concept_id": 4112,
        "concept_version_id": 11467,
        "concept_name": "Epilepsy (SNOMED-CT)",
        "coding_system": {
          "id": 9,
          "name": "SNOMED  CT codes",
          "description": "SNOMED CT codes"
        },
        "phenotype_id": "PH1699",
        "phenotype_version_id": 3626,
        "phenotype_name": "Chronic paediatric conditions: Epilepsy",
        "code_attribute_header": null,
        "codes": [
          {
            "code": "100941000119100",
            "description": "Epilepsy in mother complicating pregnancy (disorder)",
            "attributes": null
          },
          {
            "code": "10701000119109",
            "description": "Refractory complex partial seizure with impairment of consciousness (disorder)",
            "attributes": null
          },
          {
            "code": "10750951000119106",
            "description": "Epilepsy in mother complicating childbirth (disorder)",
            "attributes": null
          },
          {
            "code": "111498005",
            "description": "Extratemporal epilepsy (disorder)",
            "attributes": null
          },
          {
            "code": "116401000119105",
            "description": "Recurrent complex partial epilepsy (disorder)",
            "attributes": null
          },
          {
            "code": "117891000119100",
            "description": "Simple partial seizure (disorder)",
            "attributes": null
          },
          {
            "code": "119001000119108",
            "description": "Intractable simple partial epilepsy (disorder)",
            "attributes": null
          },
          {
            "code": "128612007",
            "description": "Focal motor seizure (disorder)",
            "attributes": null
          },
          {
            "code": "13847000",
            "description": "Partial seizure with impaired consciousness (disorder)",
            "attributes": null
          },
          {
            "code": "13973009",
            "description": "Grand mal status (disorder)",
            "attributes": null
          },
          {
            "code": "14401000119109",
            "description": "Partial frontal lobe epilepsy (disorder)",
            "attributes": null
          },
          {
            "code": "14521008",
            "description": "Visual seizure (disorder)",
            "attributes": null
          },
          {
            "code": "15523002",
            "description": "Benign focal epilepsy of childhood (disorder)",
            "attributes": null
          },
          {
            "code": "187931000119106",
            "description": "Atypical absence epilepsy (disorder)",
            "attributes": null
          },
          {
            "code": "189198006",
            "description": "Epileptic drop attack (disorder)",
            "attributes": null
          },
          {
            "code": "192845009",
            "description": "Myoclonic encephalopathy (disorder)",
            "attributes": null
          },
          {
            "code": "192979009",
            "description": "Generalized non-convulsive epilepsy (disorder)",
            "attributes": null
          },
          {
            "code": "192990004",
            "description": "Benign myoclonic epilepsy in infancy (disorder)",
            "attributes": null
          },
          {
            "code": "192999003",
            "description": "Partial epilepsy with impairment of consciousness (disorder)",
            "attributes": null
          },
          {
            "code": "193000002",
            "description": "Temporal lobe epilepsy (disorder)",
            "attributes": null
          },
          {
            "code": "193002005",
            "description": "Psychosensory epilepsy (disorder)",
            "attributes": null
          },
          {
            "code": "193003000",
            "description": "Mesiobasal limbic epilepsy (disorder)",
            "attributes": null
          },
          {
            "code": "193004006",
            "description": "Epileptic automatism (disorder)",
            "attributes": null
          },
          {
            "code": "193008009",
            "description": "Somatosensory epilepsy (disorder)",
            "attributes": null
          },
          {
            "code": "193009001",
            "description": "Partial epilepsy with autonomic symptoms (disorder)",
            "attributes": null
          },
          {
            "code": "193010006",
            "description": "Visual reflex epilepsy (disorder)",
            "attributes": null
          },
          {
            "code": "193021002",
            "description": "Cursive (running) epilepsy (disorder)",
            "attributes": null
          },
          {
            "code": "193022009",
            "description": "Localization-related(focal)(partial)idiopathic epilepsy and epileptic syndromes with seizures of localized onset (disorder)",
            "attributes": null
          },
          {
            "code": "19598007",
            "description": "Generalized epilepsy (disorder)",
            "attributes": null
          },
          {
            "code": "20121000119105",
            "description": "Partial occipital lobe epilepsy (disorder)",
            "attributes": null
          },
          {
            "code": "21391000119102",
            "description": "Partial parietal lobe epilepsy (disorder)",
            "attributes": null
          },
          {
            "code": "2198002",
            "description": "Visceral epilepsy (disorder)",
            "attributes": null
          },
          {
            "code": "230381009",
            "description": "Localization-related epilepsy (disorder)",
            "attributes": null
          },
          {
            "code": "230382002",
            "description": "Benign frontal epilepsy of childhood (disorder)",
            "attributes": null
          },
          {
            "code": "230383007",
            "description": "Benign psychomotor epilepsy of childhood (disorder)",
            "attributes": null
          },
          {
            "code": "230384001",
            "description": "Benign atypical partial epilepsy in childhood (disorder)",
            "attributes": null
          },
          {
            "code": "230386004",
            "description": "Childhood epilepsy with occipital paroxysms (disorder)",
            "attributes": null
          },
          {
            "code": "230387008",
            "description": "Benign occipital epilepsy of childhood - early onset variant (disorder)",
            "attributes": null
          },
          {
            "code": "230388003",
            "description": "Benign occipital epilepsy of childhood - late onset variant (disorder)",
            "attributes": null
          },
          {
            "code": "230389006",
            "description": "Primary inherited reading epilepsy (disorder)",
            "attributes": null
          },
          {
            "code": "230390002",
            "description": "Localization-related symptomatic epilepsy (disorder)",
            "attributes": null
          },
          {
            "code": "230391003",
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            "attributes": null
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    ],
    "status": 1,
    "doi": "https://doi.org/10.48533/93hm-9t35",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "farrellj",
    "template": {
      "id": 1,
      "name": "Clinical-Coded Phenotype",
      "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 3626,
        "version_name": "Chronic paediatric conditions: Epilepsy",
        "version_date": "2025-01-19T15:59:36.064004Z",
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      {
        "version_id": 3614,
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  }
]