[
  {
    "phenotype_id": "PH1720",
    "phenotype_version_id": 3645,
    "name": "Depression",
    "definition": "Codelists for depression.\n\nICD-10 codes ---\n\nAs per previous studies from the authors; for example, see: Jackson CA, Kerssens\nJ, Fleetwood K, Smith DJ, Mercer SW, Wild SH. Incidence of ischaemic heart disease\nand stroke among people with psychiatric disorders: retrospective cohort study. The\nBritish Journal of Psychiatry. 2020;217(2):442-449. doi:10.1192/bjp.2019.250.\n\nSNOMED codes ---Please note: this codelist was developed for use with the General\nPractice Extraction Service Data for Pandemic Planning and Research (GDPPR) dataset.\nThe GDPPR dataset only includes a subset of all SNOMED codes, hence this codelist\nmay not be appropriate for use with other datasets. The codes in this codelist come\nfrom version 47.1 of the QOF cluster list. If you are re-using this codelist with\nthe GDPPR dataset, please note that the QOF cluster list is regularly updated. We\nrecommend that you review this codelist with respect to the latest version of the\nQOF cluster list.\n\nTo develop our SNOMED codelists for mental illness (including depression) we extracted\ncodes from all of the clusters related to relevant mental illness diagnoses: DEPR_COD\n(depression diagnosis codes), DEPRES_COD (depression resolved codes) and MH_COD (psychosis\nand schizophrenia and bipolar affective disease codes) from version 47.1 of the QOF\ncluster list (which was the most recent version at the time of developing the SMI\ncodelists). Additionally, we mapped existing Read v2 and Clinical Terms Version 3\ncodelists (Prigge R, Fleetwood KJ, Jackson CA, et al. Robustly Measuring Multiple\nLong-Term Health Conditions Using Disparate Linked Datasets in UK Biobank. Available\nat SSRN: [https://ssrn.com/abstract=4863974](https://ssrn.com/abstract=4863974).) for schizophrenia, bipolar disorder and depression to SNOMED, and identified codes available within the GDPPR dataset. We collated all SNOMED codes identified from the clusters, and from the mapping process and then identified codes for each of schizophrenia, bipolar disorder or depression.\n",
    "implementation": "",
    "publications": [],
    "validation": "",
    "citation_requirements": "",
    "created": "2025-02-27T10:36:44.255486Z",
    "author": "Kelly Fleetwood, John Nolan, Daniel J Smith, Caroline A Jackson",
    "collections": [
      {
        "name": "BHF Data Science Centre",
        "value": 20
      }
    ],
    "tags": null,
    "organisation": {
      "id": 13,
      "slug": "bhf-data-science-centre",
      "name": "BHF Data Science Centre"
    },
    "world_access": 1,
    "updated": "2025-02-27T10:36:44.229654Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Disease or syndrome",
        "value": "2"
      }
    ],
    "trials": null,
    "ontology": null,
    "phenoflowid": "",
    "data_sources": [
      {
        "name": "GPES Data for Pandemic Planning and Research (COVID-19)",
        "value": 1,
        "uid": "c7eed372-9f1e-467e-8a37-948f4de5abc4",
        "url": "https://healthdatagateway.org/en/dataset/874",
        "datasource_id": 874
      },
      {
        "name": "Hospital Episode Statistics Admitted Patient Care",
        "value": 2,
        "uid": "6599230a-df54-4615-937c-d724d239491f",
        "url": "https://healthdatagateway.org/en/dataset/875",
        "datasource_id": 875
      }
    ],
    "endorsements": null,
    "project_name": "CCU046",
    "coding_system": [
      {
        "name": "SNOMED  CT codes",
        "value": 9
      },
      {
        "name": "ICD10 codes",
        "value": 4
      }
    ],
    "corresp_author": null,
    "event_date_range": "",
    "concept_information": [
      {
        "concept_id": 4195,
        "concept_version_id": 11555,
        "concept_name": "Depression",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH1720",
        "phenotype_version_id": 3645,
        "phenotype_name": "Depression",
        "code_attribute_header": null,
        "codes": [
          {
            "code": "F32",
            "description": "Depressive episode",
            "attributes": null
          },
          {
            "code": "F33",
            "description": "Recurrent depressive disorder",
            "attributes": null
          }
        ]
      },
      {
        "concept_id": 4196,
        "concept_version_id": 11556,
        "concept_name": "Depression",
        "coding_system": {
          "id": 9,
          "name": "SNOMED  CT codes",
          "description": "SNOMED CT codes"
        },
        "phenotype_id": "PH1720",
        "phenotype_version_id": 3645,
        "phenotype_name": "Depression",
        "code_attribute_header": null,
        "codes": [
          {
            "code": "104851000119103",
            "description": "Postpartum major depression in remission (disorder)",
            "attributes": null
          },
          {
            "code": "1086471000000103",
            "description": "Recurrent reactive depressive episodes, severe, with psychosis (disorder)",
            "attributes": null
          },
          {
            "code": "1086661000000108",
            "description": "Reactive depression, prolonged single episode (disorder)",
            "attributes": null
          },
          {
            "code": "1089511000000100",
            "description": "Recurrent depression with current severe episode and psychotic features (disorder)",
            "attributes": null
          },
          {
            "code": "1089631000000109",
            "description": "Recurrent depression with current severe episode without psychotic features (disorder)",
            "attributes": null
          },
          {
            "code": "1089641000000100",
            "description": "Recurrent depression with current moderate episode (disorder)",
            "attributes": null
          },
          {
            "code": "14183003",
            "description": "Chronic major depressive disorder, single episode (disorder)",
            "attributes": null
          },
          {
            "code": "15639000",
            "description": "Moderate major depression, single episode (disorder)",
            "attributes": null
          },
          {
            "code": "16238181000119101",
            "description": "Depressive disorder caused by amphetamine (disorder)",
            "attributes": null
          },
          {
            "code": "16238221000119109",
            "description": "Depressive disorder caused by methamphetamine (disorder)",
            "attributes": null
          },
          {
            "code": "16264621000119109",
            "description": "Recurrent mild major depressive disorder co-occurrent with anxiety (disorder)",
            "attributes": null
          },
          {
            "code": "16264821000119108",
            "description": "Recurrent severe major depressive disorder co-occurrent with anxiety (disorder)",
            "attributes": null
          },
          {
            "code": "16264901000119109",
            "description": "Recurrent moderate major depressive disorder co-occurrent with anxiety (disorder)",
            "attributes": null
          },
          {
            "code": "16265061000119105",
            "description": "Recurrent major depressive disorder co-occurrent with anxiety in full remission (disorder)",
            "attributes": null
          },
          {
            "code": "16265301000119106",
            "description": "Recurrent major depressive disorder in partial remission co-occurrent with anxiety (disorder)",
            "attributes": null
          },
          {
            "code": "16265951000119109",
            "description": "Mild major depressive disorder co-occurrent with anxiety single episode (disorder)",
            "attributes": null
          },
          {
            "code": "16266831000119100",
            "description": "Moderate major depressive disorder co-occurrent with anxiety single episode (disorder)",
            "attributes": null
          },
          {
            "code": "16266991000119108",
            "description": "Severe major depressive disorder co-occurrent with anxiety single episode (disorder)",
            "attributes": null
          },
          {
            "code": "18818009",
            "description": "Moderate recurrent major depression (disorder)",
            "attributes": null
          },
          {
            "code": "191455000",
            "description": "Presenile dementia with depression (disorder)",
            "attributes": null
          },
          {
            "code": "191459006",
            "description": "Senile dementia with depression (disorder)",
            "attributes": null
          },
          {
            "code": "191466007",
            "description": "Arteriosclerotic dementia with depression",
            "attributes": null
          },
          {
            "code": "191601008",
            "description": "Single major depressive episode, mild (disorder)",
            "attributes": null
          },
          {
            "code": "191602001",
            "description": "Single major depressive episode, moderate (disorder)",
            "attributes": null
          },
          {
            "code": "191604000",
            "description": "Single major depressive episode, severe, with psychosis (disorder)",
            "attributes": null
          },
          {
            "code": "191606003",
            "description": "Single major depressive episode, in full remission (disorder)",
            "attributes": null
          },
          {
            "code": "191610000",
            "description": "Recurrent major depressive episodes, mild (disorder)",
            "attributes": null
          },
          {
            "code": "191611001",
            "description": "Recurrent major depressive episodes, moderate (disorder)",
            "attributes": null
          },
          {
            "code": "191613003",
            "description": "Recurrent major depressive episodes, severe, with psychosis (disorder)",
            "attributes": null
          },
          {
            "code": "191615005",
            "description": "Recurrent major depressive episodes, in full remission (disorder)",
            "attributes": null
          },
          {
            "code": "191616006",
            "description": "Recurrent depression (disorder)",
            "attributes": null
          },
          {
            "code": "191659001",
            "description": "Atypical depressive disorder (disorder)",
            "attributes": null
          },
          {
            "code": "191676002",
            "description": "Reactive depressive psychosis (disorder)",
            "attributes": null
          },
          {
            "code": "192049004",
            "description": "Prolonged depressive adjustment reaction (disorder)",
            "attributes": null
          },
          {
            "code": "192080009",
            "description": "Chronic depression (disorder)",
            "attributes": null
          },
          {
            "code": "19527009",
            "description": "Single episode of major depression in full remission (disorder)",
            "attributes": null
          },
          {
            "code": "196381000000100",
            "description": "Depression resolved (finding)",
            "attributes": null
          },
          {
            "code": "20250007",
            "description": "Severe major depression, single episode, with psychotic features, mood-incongruent (disorder)",
            "attributes": null
          },
          {
            "code": "231499006",
            "description": "Endogenous depression first episode (disorder)",
            "attributes": null
          },
          {
            "code": "231500002",
            "description": "Masked depression (disorder)",
            "attributes": null
          },
          {
            "code": "231504006",
            "description": "Mixed anxiety and depressive disorder (disorder)",
            "attributes": null
          },
          {
            "code": "247803002",
            "description": "Seasonal affective disorder (disorder)",
            "attributes": null
          },
          {
            "code": "251000119105",
            "description": "Severe major depression, single episode (disorder)",
            "attributes": null
          },
          {
            "code": "25922000",
            "description": "Major depressive disorder, single episode with postpartum onset (disorder)",
            "attributes": null
          },
          {
            "code": "268620009",
            "description": "Single major depressive episode (disorder)",
            "attributes": null
          },
          {
            "code": "268621008",
            "description": "Recurrent major depressive episodes (disorder)",
            "attributes": null
          },
          {
            "code": "274948002",
            "description": "Endogenous depression - recurrent (disorder)",
            "attributes": null
          },
          {
            "code": "28475009",
            "description": "Severe recurrent major depression with psychotic features (disorder)",
            "attributes": null
          },
          {
            "code": "288751000119101",
            "description": "Reactive depressive psychosis, single episode (disorder)",
            "attributes": null
          },
          {
            "code": "300706003",
            "description": "Endogenous depression (disorder)",
            "attributes": null
          },
          {
            "code": "30605009",
            "description": "Major depression in partial remission (disorder)",
            "attributes": null
          },
          {
            "code": "310495003",
            "description": "Mild depression (disorder)",
            "attributes": null
          },
          {
            "code": "310496002",
            "description": "Moderate depression (disorder)",
            "attributes": null
          },
          {
            "code": "310497006",
            "description": "Severe depression (disorder)",
            "attributes": null
          },
          {
            "code": "321717001",
            "description": "Involutional depression (disorder)",
            "attributes": null
          },
          {
            "code": "33135002",
            "description": "Recurrent major depression in partial remission (disorder)",
            "attributes": null
          },
          {
            "code": "35489007",
            "description": "Depressive disorder (disorder)",
            "attributes": null
          },
          {
            "code": "357705009",
            "description": "Cotard's syndrome (disorder)",
            "attributes": null
          },
          {
            "code": "36474008",
            "description": "Severe recurrent major depression without psychotic features (disorder)",
            "attributes": null
          },
          {
            "code": "36923009",
            "description": "Major depression, single episode (disorder)",
            "attributes": null
          },
          {
            "code": "370143000",
            "description": "Major depressive disorder (disorder)",
            "attributes": null
          },
          {
            "code": "397701000000102",
            "description": "[X]Severe depressive episode without psychotic symptoms (disorder)",
            "attributes": null
          },
          {
            "code": "397711000000100",
            "description": "[X]Severe depressive episode with psychotic symptoms (disorder)",
            "attributes": null
          },
          {
            "code": "401211000000106",
            "description": "[X] Single episode major depression without psychotic symptoms (disorder)",
            "attributes": null
          },
          {
            "code": "40379007",
            "description": "Mild recurrent major depression (disorder)",
            "attributes": null
          },
          {
            "code": "40568001",
            "description": "Recurrent brief depressive disorder (disorder)",
            "attributes": null
          },
          {
            "code": "42810003",
            "description": "Major depression in remission (disorder)",
            "attributes": null
          },
          {
            "code": "42925002",
            "description": "Major depressive disorder, single episode with atypical features (disorder)",
            "attributes": null
          },
          {
            "code": "430421000000104",
            "description": "[X]Mild depressive episode (disorder)",
            "attributes": null
          },
          {
            "code": "455731000000100",
            "description": "[X] Single episode agitated depression without psychotic symptoms (disorder)",
            "attributes": null
          },
          {
            "code": "46244001",
            "description": "Recurrent major depression in full remission (disorder)",
            "attributes": null
          },
          {
            "code": "465441000000108",
            "description": "[X]Moderate depressive episode (disorder)",
            "attributes": null
          },
          {
            "code": "63412003",
            "description": "Major depression in full remission (disorder)",
            "attributes": null
          },
          {
            "code": "63778009",
            "description": "Major depressive disorder, single episode with melancholic features (disorder)",
            "attributes": null
          },
          {
            "code": "68019004",
            "description": "Recurrent major depression in remission (disorder)",
            "attributes": null
          },
          {
            "code": "69392006",
            "description": "Major depressive disorder, single episode with catatonic features (disorder)",
            "attributes": null
          },
          {
            "code": "698957003",
            "description": "Depressive disorder in remission (disorder)",
            "attributes": null
          },
          {
            "code": "70747007",
            "description": "Major depression single episode, in partial remission (disorder)",
            "attributes": null
          },
          {
            "code": "720453001",
            "description": "Moderately severe major depression single episode (disorder)",
            "attributes": null
          },
          {
            "code": "720454007",
            "description": "Minimal major depression single episode (disorder)",
            "attributes": null
          },
          {
            "code": "73867007",
            "description": "Severe major depression with psychotic features (disorder)",
            "attributes": null
          },
          {
            "code": "75084000",
            "description": "Severe major depression without psychotic features (disorder)",
            "attributes": null
          },
          {
            "code": "755321000000106",
            "description": "Single major depressive episode, severe, with psychosis, psychosis in remission (disorder)",
            "attributes": null
          },
          {
            "code": "755331000000108",
            "description": "Recurrent major depressive episodes, severe, with psychosis, psychosis in remission (disorder)",
            "attributes": null
          },
          {
            "code": "76441001",
            "description": "Severe major depression, single episode, without psychotic features (disorder)",
            "attributes": null
          },
          {
            "code": "764611000000100",
            "description": "Recurrent major depressive episodes, severe (disorder)",
            "attributes": null
          },
          {
            "code": "764631000000108",
            "description": "Single major depressive episode, severe (disorder)",
            "attributes": null
          },
          {
            "code": "764691000000109",
            "description": "Recurrent major depressive episodes, in partial remission (disorder)",
            "attributes": null
          },
          {
            "code": "764711000000106",
            "description": "Single major depressive episode, in remission (disorder)",
            "attributes": null
          },
          {
            "code": "77911002",
            "description": "Severe major depression, single episode, with psychotic features, mood-congruent (disorder)",
            "attributes": null
          },
          {
            "code": "78667006",
            "description": "Dysthymia (disorder)",
            "attributes": null
          },
          {
            "code": "788120007",
            "description": "Antenatal depression (disorder)",
            "attributes": null
          },
          {
            "code": "79298009",
            "description": "Mild major depression, single episode (disorder)",
            "attributes": null
          },
          {
            "code": "832007",
            "description": "Moderate major depression (disorder)",
            "attributes": null
          },
          {
            "code": "83458005",
            "description": "Agitated depression (disorder)",
            "attributes": null
          },
          {
            "code": "87414006",
            "description": "Reactive depression (situational) (disorder)",
            "attributes": null
          },
          {
            "code": "87512008",
            "description": "Mild major depression (disorder)",
            "attributes": null
          }
        ]
      }
    ],
    "status": 1,
    "doi": "https://doi.org/10.48533/2zg1-mc44",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "kelly.fleetwood",
    "template": {
      "id": 2,
      "name": "BHF Data Science Centre Phenotype",
      "description": "BHF Data Science Centre Phenotype definitions that describe a list of clinical codes, algorithms using clinical codes, or set of clinical trials. Visit the BHF Data Science Centre website to learn more: https://bhfdatasciencecentre.org",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 3647,
        "version_name": "Depression",
        "version_date": "2025-02-27T10:38:36.506385Z",
        "is_published": true,
        "is_latest": true
      },
      {
        "version_id": 3646,
        "version_name": "Depression",
        "version_date": "2025-02-27T10:37:44.133564Z",
        "is_published": true,
        "is_latest": false
      },
      {
        "version_id": 3645,
        "version_name": "Depression",
        "version_date": "2025-02-27T10:36:44.270266Z",
        "is_published": true,
        "is_latest": false
      }
    ]
  }
]