[
  {
    "phenotype_id": "PH190",
    "phenotype_version_id": 380,
    "name": "Hyposplenism",
    "definition": "At the specified date, a patient is defined as having had 'Hyposplenism' IF they meet the criteria for any of the following on or before the specified date. The earliest date on which the individual meets any of the following criteria on or before the specified date is defined as the first event date:\n\n\nPrimary care\n\n\n1. 'Hyposplenism' diagnosis or history of diagnosis or procedure during a consultation \n\nOR\nSecondary care (ICD10)\n\n\n1. ALL diagnoses of 'Hyposplenism' or history of diagnosis during a hospitalization\n\n\n\n\n\n\n\n\n\n\n\n\n",
    "implementation": "",
    "publications": [
      {
        "doi": "10.1016/S2589-7500(19)30012-3",
        "details": "Kuan V., Denaxas S., Gonzalez-Izquierdo A. et al. A chronological map of 308 physical and mental health conditions from 4 million individuals in the National Health Service. The Lancet Digital Health - DOI 10.1016/S2589-7500(19)30012-3"
      }
    ],
    "validation": "",
    "citation_requirements": "",
    "created": "2021-10-06T16:07:06.684561Z",
    "author": "Kuan V, Denaxas S, Gonzalez-Izquierdo A, Direk K, Bhatti O, Husain S, Sutaria S, Hingorani M, Nitsch D, Parisinos C, Lumbers T, Mathur R, Sofat R, Casas JP, Wong I, Hemingway H, Hingorani A",
    "collections": [
      {
        "name": "CALIBER",
        "value": 21
      },
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": null,
    "world_access": 1,
    "updated": "2021-10-06T16:07:06.684587Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Disease or syndrome",
        "value": "2"
      }
    ],
    "ontology": null,
    "phenoflowid": "https://kclhi.org/phenoflow/workflows/github.com/phenoflow/Hyposplenism---ac7b7600-178b-11ef-9de4-4d4ea830ad16/blob/read-potential-cases-fhir/Hyposplenism.cwl",
    "data_sources": [
      {
        "name": "CPRD GOLD",
        "value": 5,
        "uid": "a29feafa-7bdd-44e9-b977-c9d26425e67f",
        "url": "https://healthdatagateway.org/en/dataset/694",
        "datasource_id": 694
      },
      {
        "name": "HES Admitted Patient Care data for CPRD GOLD",
        "value": 9,
        "uid": "4bcf64a6-f404-4ef4-ae6e-172512ab5f43",
        "url": "https://healthdatagateway.org/en/dataset/674",
        "datasource_id": 674
      }
    ],
    "coding_system": [
      {
        "name": "ICD10 codes",
        "value": 4
      },
      {
        "name": "Read codes v2",
        "value": 5
      },
      {
        "name": "Med codes",
        "value": 8
      }
    ],
    "event_date_range": "01/01/1999 - 01/07/2016",
    "concept_information": [
      {
        "concept_id": 1230,
        "concept_version_id": 3599,
        "concept_name": "Hyposplenism - Primary care",
        "coding_system": {
          "id": 5,
          "name": "Read codes v2",
          "description": "Read codes v2"
        },
        "phenotype_id": "PH190",
        "phenotype_version_id": 380,
        "phenotype_name": "Hyposplenism",
        "code_attribute_header": [
          "Disease",
          "Medcode",
          "Category"
        ],
        "codes": [
          {
            "code": "14N7.00",
            "description": "H/O: splenectomy",
            "attributes": {
              "Disease": "Hyposplenism",
              "Medcode": "16827.0",
              "Category": "History of Hyposplenism"
            }
          },
          {
            "code": "7840.00",
            "description": "Total excision of spleen",
            "attributes": {
              "Disease": "Hyposplenism",
              "Medcode": "34310.0",
              "Category": "Procedure leading to Hyposplenism"
            }
          },
          {
            "code": "7840100.0",
            "description": "Total splenectomy",
            "attributes": {
              "Disease": "Hyposplenism",
              "Medcode": "27514.0",
              "Category": "Procedure leading to Hyposplenism"
            }
          },
          {
            "code": "7840.11",
            "description": "Total splenectomy",
            "attributes": {
              "Disease": "Hyposplenism",
              "Medcode": "2759.0",
              "Category": "Procedure leading to Hyposplenism"
            }
          },
          {
            "code": "7840300.0",
            "description": "Splenectomy NEC",
            "attributes": {
              "Disease": "Hyposplenism",
              "Medcode": "1393.0",
              "Category": "Procedure leading to Hyposplenism"
            }
          },
          {
            "code": "7840400.0",
            "description": "Laparoscopic total splenectomy",
            "attributes": {
              "Disease": "Hyposplenism",
              "Medcode": "31041.0",
              "Category": "Procedure leading to Hyposplenism"
            }
          },
          {
            "code": "7840y00",
            "description": "Other specified total excision of spleen",
            "attributes": {
              "Disease": "Hyposplenism",
              "Medcode": "102966.0",
              "Category": "Procedure leading to Hyposplenism"
            }
          },
          {
            "code": "7840z00",
            "description": "Total excision of spleen NOS",
            "attributes": {
              "Disease": "Hyposplenism",
              "Medcode": "59784.0",
              "Category": "Procedure leading to Hyposplenism"
            }
          },
          {
            "code": "7841.00",
            "description": "Other excision of spleen",
            "attributes": {
              "Disease": "Hyposplenism",
              "Medcode": "48198.0",
              "Category": "Procedure leading to Hyposplenism"
            }
          },
          {
            "code": "7841y00",
            "description": "Other specified other excision of spleen",
            "attributes": {
              "Disease": "Hyposplenism",
              "Medcode": "102207.0",
              "Category": "Procedure leading to Hyposplenism"
            }
          },
          {
            "code": "7841z00",
            "description": "Other excision of spleen NOS",
            "attributes": {
              "Disease": "Hyposplenism",
              "Medcode": "64291.0",
              "Category": "Procedure leading to Hyposplenism"
            }
          },
          {
            "code": "D415400",
            "description": "Splenic atrophy",
            "attributes": {
              "Disease": "Hyposplenism",
              "Medcode": "66973.0",
              "Category": "Diagnosis of Hyposplenism"
            }
          },
          {
            "code": "D415600",
            "description": "Splenic fibrosis",
            "attributes": {
              "Disease": "Hyposplenism",
              "Medcode": "66980.0",
              "Category": "Diagnosis of Hyposplenism"
            }
          },
          {
            "code": "D415700",
            "description": "Splenic infarction",
            "attributes": {
              "Disease": "Hyposplenism",
              "Medcode": "9368.0",
              "Category": "Diagnosis of Hyposplenism"
            }
          },
          {
            "code": "D415800",
            "description": "Non-traumatic rupture of spleen",
            "attributes": {
              "Disease": "Hyposplenism",
              "Medcode": "62557.0",
              "Category": "Diagnosis of Hyposplenism"
            }
          },
          {
            "code": "D415A00",
            "description": "Hyposplenism",
            "attributes": {
              "Disease": "Hyposplenism",
              "Medcode": "39034.0",
              "Category": "Diagnosis of Hyposplenism"
            }
          },
          {
            "code": "PK01.00",
            "description": "Absent spleen",
            "attributes": {
              "Disease": "Hyposplenism",
              "Medcode": "22319.0",
              "Category": "Diagnosis of Hyposplenism"
            }
          },
          {
            "code": "PK01.11",
            "description": "Asplenia",
            "attributes": {
              "Disease": "Hyposplenism",
              "Medcode": "10505.0",
              "Category": "Diagnosis of Hyposplenism"
            }
          },
          {
            "code": "PK06.00",
            "description": "Hypoplasia of spleen",
            "attributes": {
              "Disease": "Hyposplenism",
              "Medcode": "71462.0",
              "Category": "Diagnosis of Hyposplenism"
            }
          }
        ]
      },
      {
        "concept_id": 1231,
        "concept_version_id": 3601,
        "concept_name": "Hyposplenism - Primary care",
        "coding_system": {
          "id": 8,
          "name": "Med codes",
          "description": "Med codes"
        },
        "phenotype_id": "PH190",
        "phenotype_version_id": 380,
        "phenotype_name": "Hyposplenism",
        "code_attribute_header": [
          "Disease",
          "ReadcodeDescr",
          "Readcode"
        ],
        "codes": [
          {
            "code": "102207.0",
            "description": "Procedure leading to Hyposplenism",
            "attributes": {
              "Disease": "Hyposplenism",
              "ReadcodeDescr": "Other specified other excision of spleen",
              "Readcode": "7841y00"
            }
          },
          {
            "code": "102966.0",
            "description": "Procedure leading to Hyposplenism",
            "attributes": {
              "Disease": "Hyposplenism",
              "ReadcodeDescr": "Other specified total excision of spleen",
              "Readcode": "7840y00"
            }
          },
          {
            "code": "10505.0",
            "description": "Diagnosis of Hyposplenism",
            "attributes": {
              "Disease": "Hyposplenism",
              "ReadcodeDescr": "Asplenia",
              "Readcode": "PK01.11"
            }
          },
          {
            "code": "1393.0",
            "description": "Procedure leading to Hyposplenism",
            "attributes": {
              "Disease": "Hyposplenism",
              "ReadcodeDescr": "Splenectomy NEC",
              "Readcode": "7840300.0"
            }
          },
          {
            "code": "16827.0",
            "description": "History of Hyposplenism",
            "attributes": {
              "Disease": "Hyposplenism",
              "ReadcodeDescr": "H/O: splenectomy",
              "Readcode": "14N7.00"
            }
          },
          {
            "code": "22319.0",
            "description": "Diagnosis of Hyposplenism",
            "attributes": {
              "Disease": "Hyposplenism",
              "ReadcodeDescr": "Absent spleen",
              "Readcode": "PK01.00"
            }
          },
          {
            "code": "27514.0",
            "description": "Procedure leading to Hyposplenism",
            "attributes": {
              "Disease": "Hyposplenism",
              "ReadcodeDescr": "Total splenectomy",
              "Readcode": "7840100.0"
            }
          },
          {
            "code": "2759.0",
            "description": "Procedure leading to Hyposplenism",
            "attributes": {
              "Disease": "Hyposplenism",
              "ReadcodeDescr": "Total splenectomy",
              "Readcode": "7840.11"
            }
          },
          {
            "code": "31041.0",
            "description": "Procedure leading to Hyposplenism",
            "attributes": {
              "Disease": "Hyposplenism",
              "ReadcodeDescr": "Laparoscopic total splenectomy",
              "Readcode": "7840400.0"
            }
          },
          {
            "code": "34310.0",
            "description": "Procedure leading to Hyposplenism",
            "attributes": {
              "Disease": "Hyposplenism",
              "ReadcodeDescr": "Total excision of spleen",
              "Readcode": "7840.00"
            }
          },
          {
            "code": "39034.0",
            "description": "Diagnosis of Hyposplenism",
            "attributes": {
              "Disease": "Hyposplenism",
              "ReadcodeDescr": "Hyposplenism",
              "Readcode": "D415A00"
            }
          },
          {
            "code": "48198.0",
            "description": "Procedure leading to Hyposplenism",
            "attributes": {
              "Disease": "Hyposplenism",
              "ReadcodeDescr": "Other excision of spleen",
              "Readcode": "7841.00"
            }
          },
          {
            "code": "59784.0",
            "description": "Procedure leading to Hyposplenism",
            "attributes": {
              "Disease": "Hyposplenism",
              "ReadcodeDescr": "Total excision of spleen NOS",
              "Readcode": "7840z00"
            }
          },
          {
            "code": "62557.0",
            "description": "Diagnosis of Hyposplenism",
            "attributes": {
              "Disease": "Hyposplenism",
              "ReadcodeDescr": "Non-traumatic rupture of spleen",
              "Readcode": "D415800"
            }
          },
          {
            "code": "64291.0",
            "description": "Procedure leading to Hyposplenism",
            "attributes": {
              "Disease": "Hyposplenism",
              "ReadcodeDescr": "Other excision of spleen NOS",
              "Readcode": "7841z00"
            }
          },
          {
            "code": "66973.0",
            "description": "Diagnosis of Hyposplenism",
            "attributes": {
              "Disease": "Hyposplenism",
              "ReadcodeDescr": "Splenic atrophy",
              "Readcode": "D415400"
            }
          },
          {
            "code": "66980.0",
            "description": "Diagnosis of Hyposplenism",
            "attributes": {
              "Disease": "Hyposplenism",
              "ReadcodeDescr": "Splenic fibrosis",
              "Readcode": "D415600"
            }
          },
          {
            "code": "71462.0",
            "description": "Diagnosis of Hyposplenism",
            "attributes": {
              "Disease": "Hyposplenism",
              "ReadcodeDescr": "Hypoplasia of spleen",
              "Readcode": "PK06.00"
            }
          },
          {
            "code": "9368.0",
            "description": "Diagnosis of Hyposplenism",
            "attributes": {
              "Disease": "Hyposplenism",
              "ReadcodeDescr": "Splenic infarction",
              "Readcode": "D415700"
            }
          }
        ]
      },
      {
        "concept_id": 1232,
        "concept_version_id": 3603,
        "concept_name": "Hyposplenism - Secondary care - Diagnoses",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH190",
        "phenotype_version_id": 380,
        "phenotype_name": "Hyposplenism",
        "code_attribute_header": [
          "Disease",
          "Category"
        ],
        "codes": [
          {
            "code": "D73.0",
            "description": "Hyposplenism",
            "attributes": {
              "Disease": "Hyposplenism",
              "Category": "Diagnosis of Hyposplenism"
            }
          },
          {
            "code": "D73.5",
            "description": "Infarction of spleen",
            "attributes": {
              "Disease": "Hyposplenism",
              "Category": "Diagnosis of Hyposplenism"
            }
          }
        ]
      }
    ],
    "status": 2,
    "doi": "https://doi.org/10.48533/f1vt-td22",
    "is_deleted": null,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 1,
      "name": "Clinical-Coded Phenotype",
      "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 380,
        "version_name": "Hyposplenism",
        "version_date": "2021-10-06T16:07:06.711546Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]