[
  {
    "phenotype_id": "PH2024",
    "phenotype_version_id": 4630,
    "name": "Opioid Agonist Therapy",
    "definition": "This codelist was taken from [OpenCodelists](https://www.opencodelists.org/), created by [OpenSAFELY](https://www.opensafely.org/). We recommend viewing this Phenotype on the OpenCodelist website to view the most recent version.\n\n\nPrescription codes for Opiod Agonist Therapy (AOT).\n\n\n© University of Oxford for the Bennett Institute for Applied Data Science 2025\\. This work may be copied freely for non\\-commercial research and study.\n\n",
    "implementation": null,
    "publications": null,
    "validation": null,
    "citation_requirements": null,
    "created": "2026-01-26T21:33:34.524130Z",
    "author": "University of Bristol",
    "collections": [
      {
        "name": "OpenCodelist",
        "value": 31
      },
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": {
      "id": 1,
      "slug": "opensafely",
      "name": "OpenSAFELY"
    },
    "world_access": 1,
    "updated": "2026-01-26T21:33:34.515878Z",
    "references": [
      {
        "url": "https://portal.caliberresearch.org/phenotypes/lewer-hupio-mzxe2uzxdzvybsabtjbhrk",
        "title": "Illicit opioid use"
      },
      {
        "url": "https://wellcomeopenresearch.org/articles/5-282",
        "title": "Healthcare use by people who use illicit opioids (HUPIO): development of a cohort based on electronic primary care records in England"
      },
      {
        "url": "https://www.bristol.ac.uk/people/person/John-Macleod-8141c827-79a9-454b-b528-a5a21f8e1b91/",
        "title": "Prof. John Macleod"
      }
    ],
    "signed_off": [],
    "methodology": "This codelist was derived by the following method:\n\n\n- Codelist provided by Caliber research website.\n\n\nThis list was mapped into SNOMED\\-CT.\n\n\nThe codelist reviewed by Prof. John Macleod.\n\n",
    "coding_system": [
      {
        "name": "SNOMED  CT codes",
        "value": 9
      }
    ],
    "open_codelist_id": "bristol/opioid-agonist-therapy-oat-snomed-ct",
    "source_reference": "https://www.opencodelists.org/codelist/bristol/opioid-agonist-therapy-oat-snomed-ct/00f6d74e",
    "concept_information": [
      {
        "concept_id": 4807,
        "concept_version_id": 12292,
        "concept_name": "bristol/opioid-agonist-therapy-oat-snomed-ct/00f6d74e",
        "coding_system": {
          "id": 9,
          "name": "SNOMED  CT codes",
          "description": "SNOMED CT codes"
        },
        "phenotype_id": "PH2024",
        "phenotype_version_id": 4630,
        "phenotype_name": "Opioid Agonist Therapy",
        "code_attribute_header": [],
        "codes": [
          {
            "code": "1047881000000106",
            "description": "Opioid analgesic dependence",
            "attributes": null
          },
          {
            "code": "13187008",
            "description": "Poisoning caused by heroin",
            "attributes": null
          },
          {
            "code": "191819002",
            "description": "Continuous opioid dependence",
            "attributes": null
          },
          {
            "code": "191820008",
            "description": "Episodic opioid dependence",
            "attributes": null
          },
          {
            "code": "191821007",
            "description": "Opioid dependence in remission",
            "attributes": null
          },
          {
            "code": "191865004",
            "description": "Combined opioid with non-opioid drug dependence",
            "attributes": null
          },
          {
            "code": "191867007",
            "description": "Combined opioid with non-opioid drug dependence, continuous",
            "attributes": null
          },
          {
            "code": "191868002",
            "description": "Combined opioid with non-opioid drug dependence, episodic",
            "attributes": null
          },
          {
            "code": "191869005",
            "description": "Combined opioid with non-opioid drug dependence in remission",
            "attributes": null
          },
          {
            "code": "191909007",
            "description": "Nondependent opioid abuse",
            "attributes": null
          },
          {
            "code": "191912005",
            "description": "Nondependent opioid abuse, continuous",
            "attributes": null
          },
          {
            "code": "191913000",
            "description": "Nondependent opioid abuse, episodic",
            "attributes": null
          },
          {
            "code": "191914006",
            "description": "Nondependent opioid abuse in remission",
            "attributes": null
          },
          {
            "code": "198021000000102",
            "description": "Buprenorphine maintenance therapy",
            "attributes": null
          },
          {
            "code": "200021000000100",
            "description": "Drug addiction detoxification therapy - methadone",
            "attributes": null
          },
          {
            "code": "200031000000103",
            "description": "Drug addiction maintenance therapy - methadone",
            "attributes": null
          },
          {
            "code": "202991000000100",
            "description": "Heroin misuse",
            "attributes": null
          },
          {
            "code": "205231000000102",
            "description": "Opiate dependence detoxification",
            "attributes": null
          },
          {
            "code": "206121000000104",
            "description": "Drug addiction maintenance therapy - buprenorphine",
            "attributes": null
          },
          {
            "code": "206131000000102",
            "description": "Drug addiction detoxification therapy - buprenorphine",
            "attributes": null
          },
          {
            "code": "216463005",
            "description": "Accidental poisoning caused by heroin",
            "attributes": null
          },
          {
            "code": "226034001",
            "description": "Injecting drug user",
            "attributes": null
          },
          {
            "code": "228388006",
            "description": "Intravenous drug user",
            "attributes": null
          },
          {
            "code": "228389003",
            "description": "Groin injector",
            "attributes": null
          },
          {
            "code": "228391006",
            "description": "Drug injection behavior",
            "attributes": null
          },
          {
            "code": "228395002",
            "description": "Shares drug injecting equipment",
            "attributes": null
          },
          {
            "code": "228396001",
            "description": "Does not share drug injection equipment",
            "attributes": null
          },
          {
            "code": "231477003",
            "description": "Heroin dependence",
            "attributes": null
          },
          {
            "code": "231478008",
            "description": "Methadone dependence",
            "attributes": null
          },
          {
            "code": "231479000",
            "description": "Morphine dependence",
            "attributes": null
          },
          {
            "code": "231480002",
            "description": "Opium dependence",
            "attributes": null
          },
          {
            "code": "248601000000106",
            "description": "Neck injector",
            "attributes": null
          },
          {
            "code": "273800005",
            "description": "Severity of opiate dependence questionnaire",
            "attributes": null
          },
          {
            "code": "276981000000107",
            "description": "History of opiate misuse",
            "attributes": null
          },
          {
            "code": "277091000000105",
            "description": "History of methadone misuse",
            "attributes": null
          },
          {
            "code": "277221000000102",
            "description": "History of daily heroin misuse",
            "attributes": null
          },
          {
            "code": "277251000000107",
            "description": "History of weekly heroin misuse",
            "attributes": null
          },
          {
            "code": "277281000000101",
            "description": "Previous history of heroin misuse",
            "attributes": null
          },
          {
            "code": "277311000000103",
            "description": "History of infrequent heroin misuse",
            "attributes": null
          },
          {
            "code": "277341000000102",
            "description": "History of daily methadone misuse",
            "attributes": null
          },
          {
            "code": "277371000000108",
            "description": "History of weekly methadone misuse",
            "attributes": null
          },
          {
            "code": "277401000000105",
            "description": "History of infrequent methadone misuse",
            "attributes": null
          },
          {
            "code": "277431000000104",
            "description": "Previous history of methadone misuse",
            "attributes": null
          },
          {
            "code": "277941000000101",
            "description": "History of daily opiate misuse",
            "attributes": null
          },
          {
            "code": "277971000000107",
            "description": "History of weekly opiate misuse",
            "attributes": null
          },
          {
            "code": "278001000000102",
            "description": "History of infrequent opiate misuse",
            "attributes": null
          },
          {
            "code": "278031000000108",
            "description": "Previous history of opiate misuse",
            "attributes": null
          },
          {
            "code": "279441000000100",
            "description": "History of heroin misuse",
            "attributes": null
          },
          {
            "code": "279461000000104",
            "description": "Using heroin on top of substitution therapy",
            "attributes": null
          },
          {
            "code": "279491000000105",
            "description": "Not using heroin on top of substitution therapy",
            "attributes": null
          },
          {
            "code": "286841000000101",
            "description": "Reinduction to methadone maintenance therapy",
            "attributes": null
          },
          {
            "code": "286871000000107",
            "description": "Reinduction to buprenorphine maintenance therapy",
            "attributes": null
          },
          {
            "code": "292056009",
            "description": "Diamorphine adverse reaction",
            "attributes": null
          },
          {
            "code": "292181009",
            "description": "Cocaine adverse reaction",
            "attributes": null
          },
          {
            "code": "304681000000107",
            "description": "Opioid agonist substitution therapy",
            "attributes": null
          },
          {
            "code": "31956009",
            "description": "Cocaine dependence",
            "attributes": null
          },
          {
            "code": "391102000",
            "description": "Failed heroin detoxification",
            "attributes": null
          },
          {
            "code": "416479009",
            "description": "Previously injecting drug user",
            "attributes": null
          },
          {
            "code": "439720003",
            "description": "Has never shared drug injection equipment",
            "attributes": null
          },
          {
            "code": "450361001",
            "description": "Clinical opiate withdrawal scale",
            "attributes": null
          },
          {
            "code": "712545004",
            "description": "Abstinent from drug misuse on maintenance replacement",
            "attributes": null
          },
          {
            "code": "768691000000103",
            "description": "Drug addiction maintenance therapy - naltrexone",
            "attributes": null
          },
          {
            "code": "768711000000101",
            "description": "Drug addiction maintenance therapy - lofexidine",
            "attributes": null
          },
          {
            "code": "891951000000109",
            "description": "Opioid substitution therapy monitoring",
            "attributes": null
          }
        ]
      }
    ],
    "coding_system_release": "",
    "open_codelist_version_id": "00f6d74e",
    "open_codelist_version_tag": "",
    "status": 1,
    "doi": "https://doi.org/10.48533/p0vz-e366",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 3,
      "name": "OpenCodelists Phenotype",
      "description": "OpenSafely's OpenCodelist Phenotype, visit https://www.opencodelists.org/ to learn more",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 4630,
        "version_name": "Opioid Agonist Therapy",
        "version_date": "2026-01-26T21:33:34.534141Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]