[
  {
    "phenotype_id": "PH2154",
    "phenotype_version_id": 4901,
    "name": "Tyrosine kinase inhibitor systemic medication codes",
    "definition": "This codelist was taken from [OpenCodelists](https://www.opencodelists.org/), created by [OpenSAFELY](https://www.opensafely.org/). We recommend viewing this Phenotype on the OpenCodelist website to view the most recent version.\n\n\nTaken from the `TKIDRUG_COD` NHS drug refset. Contains public sector information licensed under the UK Open Government Licence v3\\.0 (https://www.nationalarchives.gov.uk/doc/open\\-government\\-licence/version/3/).\n\n\n© University of Oxford for the Bennett Institute for Applied Data Science 2025\\. This work may be copied freely for non\\-commercial research and study.\n\n",
    "implementation": null,
    "publications": null,
    "validation": null,
    "citation_requirements": null,
    "created": "2026-01-26T21:51:26.828714Z",
    "author": "NHS Drug Refsets",
    "collections": [
      {
        "name": "OpenCodelist",
        "value": 31
      },
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": {
      "id": 1,
      "slug": "opensafely",
      "name": "OpenSAFELY"
    },
    "world_access": 1,
    "updated": "2026-01-26T21:51:28.217388Z",
    "references": [],
    "signed_off": [],
    "methodology": "This codelist was imported automatically. The following codes were not found in the Dictionary of Medicines and Devices dictionary and so excluded from this codelist: 414461007, 703584008, 703581000, 407797002, 703640000, 703583002, 703639002, 426269005, 414462000, 410950003\\.\n\n\nThis may be because this codelist contains both clinical terms and medications. In which case you may need to create another codelist for the missing clinical/medication codes.\n\n",
    "coding_system": [
      {
        "name": "dm+d codes",
        "value": 23
      }
    ],
    "open_codelist_id": "nhs-drug-refsets/tkidrug_cod",
    "source_reference": "https://www.opencodelists.org/codelist/nhs-drug-refsets/tkidrug_cod/20250912",
    "concept_information": [
      {
        "concept_id": 5078,
        "concept_version_id": 12563,
        "concept_name": "nhs-drug-refsets/tkidrug_cod/20250912",
        "coding_system": {
          "id": 23,
          "name": "dm+d codes",
          "description": "dm+d codes"
        },
        "phenotype_id": "PH2154",
        "phenotype_version_id": 4901,
        "phenotype_name": "Tyrosine kinase inhibitor systemic medication codes",
        "code_attribute_header": [],
        "codes": [
          {
            "code": "13667811000001109",
            "description": "Tyverb 250mg tablets (Novartis Pharmaceuticals UK Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "18190611000001106",
            "description": "Glivec 100mg tablets (Mawdsley-Brooks & Company Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "20358611000001109",
            "description": "Caprelsa 100mg tablets (Sanofi) (AMP)",
            "attributes": null
          },
          {
            "code": "20358911000001103",
            "description": "Caprelsa 300mg tablets (Sanofi) (AMP)",
            "attributes": null
          },
          {
            "code": "20363411000001107",
            "description": "Vandetanib 100mg tablets (VMP)",
            "attributes": null
          },
          {
            "code": "20363511000001106",
            "description": "Vandetanib 300mg tablets (VMP)",
            "attributes": null
          },
          {
            "code": "21210111000001107",
            "description": "Xalkori 250mg capsules (Imported (United States)) (AMP)",
            "attributes": null
          },
          {
            "code": "21596111000001101",
            "description": "Xalkori 250mg capsules (Pfizer Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "21598111000001102",
            "description": "Xalkori 200mg capsules (Pfizer Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "23410511000001105",
            "description": "Gilotrif 30mg tablets (Imported (United States)) (AMP)",
            "attributes": null
          },
          {
            "code": "23410811000001108",
            "description": "Gilotrif 40mg tablets (Imported (United States)) (AMP)",
            "attributes": null
          },
          {
            "code": "23411111000001107",
            "description": "Gilotrif 20mg tablets (Imported (United States)) (AMP)",
            "attributes": null
          },
          {
            "code": "23855511000001104",
            "description": "Giotrif 20mg tablets (Boehringer Ingelheim Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "23858411000001108",
            "description": "Giotrif 30mg tablets (Boehringer Ingelheim Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "23859211000001104",
            "description": "Giotrif 40mg tablets (Boehringer Ingelheim Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "23861011000001101",
            "description": "Giotrif 50mg tablets (Boehringer Ingelheim Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "23905211000001104",
            "description": "Afatinib 50mg tablets (VMP)",
            "attributes": null
          },
          {
            "code": "28282411000001107",
            "description": "Imbruvica 140mg capsules (Janssen-Cilag Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "28395011000001103",
            "description": "Ibrutinib 140mg capsules (VMP)",
            "attributes": null
          },
          {
            "code": "28782311000001106",
            "description": "Vargatef 100mg capsules (Boehringer Ingelheim Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "28782611000001101",
            "description": "Vargatef 150mg capsules (Boehringer Ingelheim Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "28790211000001100",
            "description": "Nintedanib 100mg capsules (VMP)",
            "attributes": null
          },
          {
            "code": "28790311000001108",
            "description": "Nintedanib 150mg capsules (VMP)",
            "attributes": null
          },
          {
            "code": "30768311000001108",
            "description": "Ofev 100mg capsules (Boehringer Ingelheim Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "30768811000001104",
            "description": "Ofev 150mg capsules (Boehringer Ingelheim Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "33750211000001108",
            "description": "Imatinib 400mg tablets (Teva UK Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "33750411000001107",
            "description": "Imatinib 100mg tablets (Teva UK Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "33757711000001100",
            "description": "Imatinib 100mg tablets (Actavis UK Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "33757911000001103",
            "description": "Imatinib 400mg tablets (Actavis UK Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "33760511000001104",
            "description": "Imatinib 100mg tablets (Esteve Pharmaceuticals Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "33760711000001109",
            "description": "Imatinib 400mg tablets (Esteve Pharmaceuticals Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "33866911000001106",
            "description": "Imatinib 100mg tablets (A A H Pharmaceuticals Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "33867211000001100",
            "description": "Imatinib 400mg tablets (A A H Pharmaceuticals Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "33931011000001102",
            "description": "Imatinib 100mg tablets (Wockhardt UK Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "33959611000001106",
            "description": "Imatinib 400mg tablets (Wockhardt UK Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "34024011000001105",
            "description": "Imatinib 100mg capsules (Dr Reddy's Laboratories (UK) Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "34024411000001101",
            "description": "Imatinib 400mg capsules (Dr Reddy's Laboratories (UK) Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "34025211000001104",
            "description": "Imatinib 100mg tablets (Dr Reddy's Laboratories (UK) Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "34025411000001100",
            "description": "Imatinib 400mg tablets (Dr Reddy's Laboratories (UK) Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "34034411000001103",
            "description": "Imatinib 100mg tablets (Accord-UK Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "34034611000001100",
            "description": "Imatinib 400mg tablets (Accord-UK Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "34166411000001105",
            "description": "Imatinib 100mg tablets (Sandoz Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "34166611000001108",
            "description": "Imatinib 400mg tablets (Sandoz Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "34187811000001107",
            "description": "Imatinib 100mg capsules (A A H Pharmaceuticals Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "34209411000001100",
            "description": "Imatinib 100mg tablets (Viatris UK Healthcare Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "34210011000001103",
            "description": "Imatinib 400mg tablets (Viatris UK Healthcare Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "34576411000001106",
            "description": "Nibix 100mg capsules (Rivopharm (UK) Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "34576611000001109",
            "description": "Nibix 400mg capsules (Rivopharm (UK) Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "35245311000001107",
            "description": "Imatinib 100mg tablets (Milpharm Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "35245511000001101",
            "description": "Imatinib 400mg tablets (Milpharm Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "37492311000001108",
            "description": "Imbruvica 420mg tablets (Janssen-Cilag Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "37492611000001103",
            "description": "Imbruvica 560mg tablets (Janssen-Cilag Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "37492911000001109",
            "description": "Imbruvica 140mg tablets (Janssen-Cilag Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "37493211000001106",
            "description": "Imbruvica 280mg tablets (Janssen-Cilag Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "37493411000001105",
            "description": "Ibrutinib 140mg tablets (VMP)",
            "attributes": null
          },
          {
            "code": "37493511000001109",
            "description": "Ibrutinib 280mg tablets (VMP)",
            "attributes": null
          },
          {
            "code": "37493611000001108",
            "description": "Ibrutinib 420mg tablets (VMP)",
            "attributes": null
          },
          {
            "code": "37493711000001104",
            "description": "Ibrutinib 560mg tablets (VMP)",
            "attributes": null
          },
          {
            "code": "37603711000001100",
            "description": "Imatinib 100mg tablets (Zentiva Pharma UK Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "37603911000001103",
            "description": "Imatinib 400mg tablets (Zentiva Pharma UK Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "39063811000001108",
            "description": "Ayvakyt 100mg tablets (Blueprint Medicines (UK) Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "39064111000001104",
            "description": "Ayvakyt 200mg tablets (Blueprint Medicines (UK) Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "39064611000001107",
            "description": "Ayvakyt 300mg tablets (Blueprint Medicines (UK) Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "39077011000001100",
            "description": "Avapritinib 100mg tablets (VMP)",
            "attributes": null
          },
          {
            "code": "39077111000001104",
            "description": "Avapritinib 200mg tablets (VMP)",
            "attributes": null
          },
          {
            "code": "39077211000001105",
            "description": "Avapritinib 300mg tablets (VMP)",
            "attributes": null
          },
          {
            "code": "39291911000001106",
            "description": "Xalkori 200mg capsules (Originalis B.V.) (AMP)",
            "attributes": null
          },
          {
            "code": "39292111000001103",
            "description": "Xalkori 250mg capsules (Originalis B.V.) (AMP)",
            "attributes": null
          },
          {
            "code": "39345111000001108",
            "description": "Imatinib 80mg/ml oral solution sugar free (Rosemont Pharmaceuticals Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "39405611000001100",
            "description": "Imatinib 80mg/ml oral solution sugar free (VMP)",
            "attributes": null
          },
          {
            "code": "39695811000001101",
            "description": "Imatinib 100mg capsules (VMP)",
            "attributes": null
          },
          {
            "code": "39695911000001106",
            "description": "Imatinib 400mg capsules (VMP)",
            "attributes": null
          },
          {
            "code": "39696011000001103",
            "description": "Imatinib 100mg tablets (VMP)",
            "attributes": null
          },
          {
            "code": "39696111000001102",
            "description": "Imatinib 400mg tablets (VMP)",
            "attributes": null
          },
          {
            "code": "39697211000001105",
            "description": "Lapatinib 250mg tablets (VMP)",
            "attributes": null
          },
          {
            "code": "39726011000001101",
            "description": "Afatinib 20mg tablets (VMP)",
            "attributes": null
          },
          {
            "code": "39726211000001106",
            "description": "Afatinib 30mg tablets (VMP)",
            "attributes": null
          },
          {
            "code": "39727811000001109",
            "description": "Afatinib 40mg tablets (VMP)",
            "attributes": null
          },
          {
            "code": "41194811000001105",
            "description": "Imatinib 100mg tablets (Amarox Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "41195711000001103",
            "description": "Imatinib 400mg tablets (Amarox Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "41211611000001107",
            "description": "Imatinib 600mg tablets (Amarox Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "41213311000001101",
            "description": "Imatinib 600mg tablets (VMP)",
            "attributes": null
          },
          {
            "code": "41531711000001103",
            "description": "Imatinib 400mg capsules (Cipla EU Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "41760611000001109",
            "description": "Crizotinib 200mg capsules (VMP)",
            "attributes": null
          },
          {
            "code": "41760811000001108",
            "description": "Crizotinib 250mg capsules (VMP)",
            "attributes": null
          },
          {
            "code": "42143411000001103",
            "description": "Sotyktu 6mg tablets (Bristol-Myers Squibb Pharmaceuticals Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "42174811000001104",
            "description": "Deucravacitinib 6mg tablets (VMP)",
            "attributes": null
          },
          {
            "code": "42712411000001109",
            "description": "Imatinib 100mg tablets (Orion Pharma (UK) Ltd) (AMP)",
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          },
          {
            "code": "42712811000001106",
            "description": "Imatinib 400mg tablets (Orion Pharma (UK) Ltd) (AMP)",
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          },
          {
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          },
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          },
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          },
          {
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          },
          {
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            "description": "Avapritinib 25mg tablets (VMP)",
            "attributes": null
          },
          {
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            "description": "Avapritinib 50mg tablets (VMP)",
            "attributes": null
          },
          {
            "code": "7319811000001103",
            "description": "Glivec 400mg tablets (Novartis Pharmaceuticals UK Ltd) (AMP)",
            "attributes": null
          },
          {
            "code": "8089611000001108",
            "description": "Glivec 100mg tablets (Novartis Pharmaceuticals UK Ltd) (AMP)",
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          }
        ]
      }
    ],
    "coding_system_release": "",
    "open_codelist_version_id": "05b40c3e",
    "open_codelist_version_tag": "20250912",
    "status": 1,
    "doi": "https://doi.org/10.48533/76c0-wy36",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 3,
      "name": "OpenCodelists Phenotype",
      "description": "OpenSafely's OpenCodelist Phenotype, visit https://www.opencodelists.org/ to learn more",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 4901,
        "version_name": "Tyrosine kinase inhibitor systemic medication codes",
        "version_date": "2026-01-26T21:51:28.230476Z",
        "is_published": true,
        "is_latest": true
      },
      {
        "version_id": 4900,
        "version_name": "Tyrosine kinase inhibitor systemic medication codes",
        "version_date": "2026-01-26T21:51:26.840706Z",
        "is_published": true,
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      }
    ]
  }
]