[
  {
    "phenotype_id": "PH2274",
    "phenotype_version_id": 5288,
    "name": "Brain cancer diagnosis codes",
    "definition": "This codelist was taken from [OpenCodelists](https://www.opencodelists.org/), created by [OpenSAFELY](https://www.opensafely.org/). We recommend viewing this Phenotype on the OpenCodelist website to view the most recent version.\n\n\nTaken from the `BRAINCAN_COD` refset published by NHSD. Contains public sector information licensed under the UK Open Government Licence v3\\.0 (https://www.nationalarchives.gov.uk/doc/open\\-government\\-licence/version/3/).\n\n\n© University of Oxford for the Bennett Institute for Applied Data Science 2025\\. This work may be copied freely for non\\-commercial research and study.\n\n",
    "implementation": null,
    "publications": null,
    "validation": null,
    "citation_requirements": null,
    "created": "2026-01-26T21:58:57.879920Z",
    "author": "NHSD Primary Care Domain Refsets",
    "collections": [
      {
        "name": "OpenCodelist",
        "value": 31
      },
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": {
      "id": 1,
      "slug": "opensafely",
      "name": "OpenSAFELY"
    },
    "world_access": 1,
    "updated": "2026-01-26T21:59:01.338009Z",
    "references": [],
    "signed_off": [],
    "methodology": "",
    "coding_system": [
      {
        "name": "SNOMED  CT codes",
        "value": 9
      }
    ],
    "open_codelist_id": "nhsd-primary-care-domain-refsets/braincan_cod",
    "source_reference": "https://www.opencodelists.org/codelist/nhsd-primary-care-domain-refsets/braincan_cod/20250912",
    "concept_information": [
      {
        "concept_id": 5465,
        "concept_version_id": 12950,
        "concept_name": "nhsd-primary-care-domain-refsets/braincan_cod/20250912",
        "coding_system": {
          "id": 9,
          "name": "SNOMED  CT codes",
          "description": "SNOMED CT codes"
        },
        "phenotype_id": "PH2274",
        "phenotype_version_id": 5288,
        "phenotype_name": "Brain cancer diagnosis codes",
        "code_attribute_header": [],
        "codes": [
          {
            "code": "100721000119109",
            "description": "High grade astrocytoma of brain",
            "attributes": null
          },
          {
            "code": "100731000119107",
            "description": "Low grade astrocytoma of brain",
            "attributes": null
          },
          {
            "code": "104981000119104",
            "description": "Oligodendroglioma of cerebrum",
            "attributes": null
          },
          {
            "code": "107581000119103",
            "description": "Astrocytoma of brain stem",
            "attributes": null
          },
          {
            "code": "1081211000119108",
            "description": "Left primary malignant olfactory neuroblastoma",
            "attributes": null
          },
          {
            "code": "1081221000119101",
            "description": "Right primary malignant olfactory neuroblastoma",
            "attributes": null
          },
          {
            "code": "109912006",
            "description": "Overlapping malignant neoplasm of brain",
            "attributes": null
          },
          {
            "code": "11471000224106",
            "description": "Diffuse intrinsic pontine glioma",
            "attributes": null
          },
          {
            "code": "1155991005",
            "description": "Metastatic malignant neoplasm to leptomeninges",
            "attributes": null
          },
          {
            "code": "1156413005",
            "description": "Gliomatosis cerebri",
            "attributes": null
          },
          {
            "code": "1156414004",
            "description": "Giant cell glioblastoma of brain",
            "attributes": null
          },
          {
            "code": "1156415003",
            "description": "Protoplasmic astrocytoma of brain",
            "attributes": null
          },
          {
            "code": "1156416002",
            "description": "Gemistocytic astrocytoma of brain",
            "attributes": null
          },
          {
            "code": "1156417006",
            "description": "Fibrillary astrocytoma of brain",
            "attributes": null
          },
          {
            "code": "1156455001",
            "description": "Pleomorphic xanthoastrocytoma of brain",
            "attributes": null
          },
          {
            "code": "1156456000",
            "description": "Pilomyxoid astrocytoma of brain",
            "attributes": null
          },
          {
            "code": "1156460002",
            "description": "Desmoplastic nodular medulloblastoma of brain",
            "attributes": null
          },
          {
            "code": "1156461003",
            "description": "Gliosarcoma of brain",
            "attributes": null
          },
          {
            "code": "1156469001",
            "description": "Large cell medulloblastoma of brain",
            "attributes": null
          },
          {
            "code": "1156471001",
            "description": "Choroid plexus carcinoma",
            "attributes": null
          },
          {
            "code": "1156472008",
            "description": "Papillary tumor of pineal region",
            "attributes": null
          },
          {
            "code": "1157060001",
            "description": "Diffuse astrocytoma of brain",
            "attributes": null
          },
          {
            "code": "1196839006",
            "description": "Primary embryonal carcinoma of brain",
            "attributes": null
          },
          {
            "code": "1196844004",
            "description": "Primary malignant astrocytoma of brain",
            "attributes": null
          },
          {
            "code": "1196860000",
            "description": "Primary anaplastic large cell medulloblastoma of brain",
            "attributes": null
          },
          {
            "code": "1196898000",
            "description": "Primary malignant atypical teratoid rhabdoid neoplasm of brain",
            "attributes": null
          },
          {
            "code": "1197298003",
            "description": "Primary malignant germ cell neoplasm of pineal gland",
            "attributes": null
          },
          {
            "code": "1217383007",
            "description": "RELA fusion-positive supratentorial ependymoma",
            "attributes": null
          },
          {
            "code": "1231267007",
            "description": "Primary malignant ependymoma of optic nerve",
            "attributes": null
          },
          {
            "code": "1237425009",
            "description": "Metastatic carcinoma to pituitary",
            "attributes": null
          },
          {
            "code": "1237578005",
            "description": "Primary oculocerebral non-Hodgkin lymphoma",
            "attributes": null
          },
          {
            "code": "1251456000",
            "description": "Metastatic neuroblastoma to brain",
            "attributes": null
          },
          {
            "code": "1251484005",
            "description": "Metastatic adenocarcinoma to pituitary gland",
            "attributes": null
          },
          {
            "code": "1259425005",
            "description": "Primary neuroblastoma of brain",
            "attributes": null
          },
          {
            "code": "1259492003",
            "description": "Dementia due to metastatic malignant neoplasm to brain",
            "attributes": null
          },
          {
            "code": "1259629009",
            "description": "Primary adenocarcinoma of pituitary gland",
            "attributes": null
          },
          {
            "code": "1259692005",
            "description": "Primary gliosarcoma of brain",
            "attributes": null
          },
          {
            "code": "1259720004",
            "description": "Primary malignant glioma of brain",
            "attributes": null
          },
          {
            "code": "1259722007",
            "description": "Primary glioblastoma multiforme of brain",
            "attributes": null
          },
          {
            "code": "1259724008",
            "description": "Primary anaplastic astrocytoma of brain",
            "attributes": null
          },
          {
            "code": "1259725009",
            "description": "Primary medulloblastoma of cerebellum",
            "attributes": null
          },
          {
            "code": "1259730008",
            "description": "Primary oligodendroglioma of brain",
            "attributes": null
          },
          {
            "code": "1259731007",
            "description": "Primary astrocytoma of spinal cord",
            "attributes": null
          },
          {
            "code": "1259733005",
            "description": "Primary malignant astrocytoma of optic nerve",
            "attributes": null
          },
          {
            "code": "1259734004",
            "description": "Primary malignant meningioma of optic nerve sheath",
            "attributes": null
          },
          {
            "code": "1259739009",
            "description": "Primary malignant glioma of hypothalamus",
            "attributes": null
          },
          {
            "code": "1259740006",
            "description": "Primary malignant glioma of cerebellum",
            "attributes": null
          },
          {
            "code": "1259742003",
            "description": "Primary malignant glioma of cerebrum",
            "attributes": null
          },
          {
            "code": "1259743008",
            "description": "Primary astrocytoma of brain stem",
            "attributes": null
          },
          {
            "code": "1259749007",
            "description": "Primary malignant meningioma of meninges of brain",
            "attributes": null
          },
          {
            "code": "1259750007",
            "description": "Primary astrocytoma of cerebrum",
            "attributes": null
          },
          {
            "code": "1259762006",
            "description": "Primary malignant optic glioma of adulthood",
            "attributes": null
          },
          {
            "code": "1259764007",
            "description": "Primary supratentorial primitive neuroectodermal tumor",
            "attributes": null
          },
          {
            "code": "1259765008",
            "description": "Primary classic medulloblastoma",
            "attributes": null
          },
          {
            "code": "1259769002",
            "description": "Primary malignant glioma of brainstem",
            "attributes": null
          },
          {
            "code": "1259770001",
            "description": "Primary anaplastic glioma of brain",
            "attributes": null
          },
          {
            "code": "1259773004",
            "description": "Primary anaplastic astrocytoma of spinal cord",
            "attributes": null
          },
          {
            "code": "1259787004",
            "description": "Primary malignant optic glioma",
            "attributes": null
          },
          {
            "code": "1259798003",
            "description": "Primary oligodendroglioma of cerebrum",
            "attributes": null
          },
          {
            "code": "1259812009",
            "description": "Primary astroblastoma of brain",
            "attributes": null
          },
          {
            "code": "1259814005",
            "description": "Primary gemistocytic astrocytoma of brain",
            "attributes": null
          },
          {
            "code": "1259815006",
            "description": "Primary giant cell glioblastoma of brain",
            "attributes": null
          },
          {
            "code": "1259816007",
            "description": "Primary fibrillary astrocytoma of brain",
            "attributes": null
          },
          {
            "code": "1259817003",
            "description": "Primary pleomorphic xanthoastrocytoma of brain",
            "attributes": null
          },
          {
            "code": "1259818008",
            "description": "Primary pilomyxoid astrocytoma of brain",
            "attributes": null
          },
          {
            "code": "1263578000",
            "description": "Increased cerebrospinal fluid production due to choroid plexus carcinoma",
            "attributes": null
          },
          {
            "code": "1268352008",
            "description": "Primary carcinoma of pituitary gland",
            "attributes": null
          },
          {
            "code": "1268528000",
            "description": "Primary olfactory neuroblastoma",
            "attributes": null
          },
          {
            "code": "1268702001",
            "description": "Primary choroid plexus carcinoma",
            "attributes": null
          },
          {
            "code": "1268716006",
            "description": "Primary medulloblastoma",
            "attributes": null
          },
          {
            "code": "1268888008",
            "description": "Primary pineal parenchymal tumor of intermediate differentiation",
            "attributes": null
          },
          {
            "code": "1268957005",
            "description": "Primary pineoblastoma",
            "attributes": null
          },
          {
            "code": "1268961004",
            "description": "Primary diffuse astrocytoma of brain",
            "attributes": null
          },
          {
            "code": "1268966009",
            "description": "Primary gliomatosis cerebri",
            "attributes": null
          },
          {
            "code": "1269042005",
            "description": "Primary protoplasmic astrocytoma of brain",
            "attributes": null
          },
          {
            "code": "1269047004",
            "description": "Primary papillary tumor of pineal region",
            "attributes": null
          },
          {
            "code": "1269048009",
            "description": "Primary diffuse intrinsic pontine glioma",
            "attributes": null
          },
          {
            "code": "1269051002",
            "description": "Primary desmoplastic nodular medulloblastoma of brain",
            "attributes": null
          },
          {
            "code": "1269052009",
            "description": "Primary large cell medulloblastoma of brain",
            "attributes": null
          },
          {
            "code": "147111000119106",
            "description": "Oligodendroglioma of central nervous system",
            "attributes": null
          },
          {
            "code": "15955101000119101",
            "description": "Primary malignant neoplasm of right greater vestibular gland",
            "attributes": null
          },
          {
            "code": "16845301000119108",
            "description": "Primary glioblastoma multiforme of cerebellum",
            "attributes": null
          },
          {
            "code": "16845341000119105",
            "description": "Primary glioblastoma multiforme of brainstem",
            "attributes": null
          },
          {
            "code": "188280007",
            "description": "Malignant neoplasm of cerebrum (excluding lobes and ventricles)",
            "attributes": null
          },
          {
            "code": "188281006",
            "description": "Malignant neoplasm of basal ganglia",
            "attributes": null
          },
          {
            "code": "188282004",
            "description": "Malignant neoplasm of cerebral cortex",
            "attributes": null
          },
          {
            "code": "188283009",
            "description": "Malignant neoplasm of corpus striatum",
            "attributes": null
          },
          {
            "code": "188285002",
            "description": "Malignant neoplasm of globus pallidus",
            "attributes": null
          },
          {
            "code": "188286001",
            "description": "Malignant neoplasm of hypothalamus",
            "attributes": null
          },
          {
            "code": "188287005",
            "description": "Malignant neoplasm of thalamus",
            "attributes": null
          },
          {
            "code": "188288000",
            "description": "Malignant neoplasm of cerebrum NOS",
            "attributes": null
          },
          {
            "code": "188289008",
            "description": "Malignant neoplasm of hippocampus",
            "attributes": null
          },
          {
            "code": "188290004",
            "description": "Malignant neoplasm of uncus",
            "attributes": null
          },
          {
            "code": "188291000",
            "description": "Malignant neoplasm of temporal lobe NOS",
            "attributes": null
          },
          {
            "code": "188292007",
            "description": "Malignant neoplasm of choroid plexus",
            "attributes": null
          },
          {
            "code": "188293002",
            "description": "Malignant neoplasm of floor of cerebral ventricle",
            "attributes": null
          },
          {
            "code": "188294008",
            "description": "Malignant neoplasm of cerebral ventricle NOS",
            "attributes": null
          },
          {
            "code": "188295009",
            "description": "Malignant neoplasm of cerebral peduncle",
            "attributes": null
          },
          {
            "code": "188296005",
            "description": "Malignant neoplasm of medulla oblongata",
            "attributes": null
          },
          {
            "code": "188297001",
            "description": "Malignant neoplasm of midbrain",
            "attributes": null
          },
          {
            "code": "188298006",
            "description": "Malignant neoplasm of pons",
            "attributes": null
          },
          {
            "code": "188299003",
            "description": "Malignant neoplasm of brainstem NOS",
            "attributes": null
          },
          {
            "code": "188301005",
            "description": "Malignant neoplasm of corpus callosum",
            "attributes": null
          },
          {
            "code": "188302003",
            "description": "Malignant neoplasm of tapetum",
            "attributes": null
          },
          {
            "code": "188308004",
            "description": "Malignant neoplasm of olfactory bulb",
            "attributes": null
          },
          {
            "code": "188339002",
            "description": "Malignant neoplasm of pituitary gland and craniopharyngeal duct",
            "attributes": null
          },
          {
            "code": "188340000",
            "description": "Malignant neoplasm of craniopharyngeal duct",
            "attributes": null
          },
          {
            "code": "188341001",
            "description": "Malignant neoplasm of pituitary gland or craniopharyngeal duct NOS",
            "attributes": null
          },
          {
            "code": "188462001",
            "description": "Metastatic malignant neoplasm to brain and spinal cord",
            "attributes": null
          },
          {
            "code": "254938000",
            "description": "Astrocytoma of brain",
            "attributes": null
          },
          {
            "code": "254940005",
            "description": "Oligodendroglioma of brain",
            "attributes": null
          },
          {
            "code": "254955001",
            "description": "Pituitary carcinoma",
            "attributes": null
          },
          {
            "code": "254969001",
            "description": "Malignant neoplasm of olfactory tract",
            "attributes": null
          },
          {
            "code": "254973003",
            "description": "Malignant astrocytoma of optic nerve",
            "attributes": null
          },
          {
            "code": "255044008",
            "description": "Malignant pinealoma",
            "attributes": null
          },
          {
            "code": "255112006",
            "description": "Malignant neoplasm of pituitary and hypothalamus",
            "attributes": null
          },
          {
            "code": "275464006",
            "description": "Cerebral tumor - malignant",
            "attributes": null
          },
          {
            "code": "276826005",
            "description": "Malignant glioma of brain",
            "attributes": null
          },
          {
            "code": "276828006",
            "description": "Glioblastoma multiforme of brain",
            "attributes": null
          },
          {
            "code": "277461004",
            "description": "Anaplastic astrocytoma of brain",
            "attributes": null
          },
          {
            "code": "277505007",
            "description": "Medulloblastoma of cerebellum",
            "attributes": null
          },
          {
            "code": "281560004",
            "description": "Neuroblastoma of brain",
            "attributes": null
          },
          {
            "code": "285641009",
            "description": "Metastasis to brain of unknown primary",
            "attributes": null
          },
          {
            "code": "350621000119100",
            "description": "Primary malignant neoplasm of right vestibulocochlear nerve",
            "attributes": null
          },
          {
            "code": "350631000119102",
            "description": "Primary malignant neoplasm of left vestibulocochlear nerve",
            "attributes": null
          },
          {
            "code": "352911000119101",
            "description": "Primary malignant neoplasm of left optic nerve",
            "attributes": null
          },
          {
            "code": "352921000119108",
            "description": "Primary malignant neoplasm of right optic nerve",
            "attributes": null
          },
          {
            "code": "363467004",
            "description": "Malignant neoplasm of frontal lobe",
            "attributes": null
          },
          {
            "code": "363468009",
            "description": "Malignant neoplasm of temporal lobe",
            "attributes": null
          },
          {
            "code": "363469001",
            "description": "Malignant neoplasm of parietal lobe",
            "attributes": null
          },
          {
            "code": "363470000",
            "description": "Malignant neoplasm of occipital lobe",
            "attributes": null
          },
          {
            "code": "363471001",
            "description": "Malignant neoplasm of ventricle of brain",
            "attributes": null
          },
          {
            "code": "363473003",
            "description": "Malignant neoplasm of brainstem",
            "attributes": null
          },
          {
            "code": "363482009",
            "description": "Malignant neoplasm of pituitary gland",
            "attributes": null
          },
          {
            "code": "363483004",
            "description": "Malignant neoplasm of pineal gland",
            "attributes": null
          },
          {
            "code": "421283008",
            "description": "Primary lymphoma of brain with acquired immunodeficiency syndrome",
            "attributes": null
          },
          {
            "code": "424151006",
            "description": "Anaplastic glioma of brain",
            "attributes": null
          },
          {
            "code": "424276002",
            "description": "Malignant glioma of brainstem",
            "attributes": null
          },
          {
            "code": "428061005",
            "description": "Malignant neoplasm of brain",
            "attributes": null
          },
          {
            "code": "429033009",
            "description": "Malignant neoplasm of cerebrum",
            "attributes": null
          },
          {
            "code": "443333004",
            "description": "Medulloblastoma",
            "attributes": null
          },
          {
            "code": "448218008",
            "description": "Malignant neoplasm of cerebellopontine angle",
            "attributes": null
          },
          {
            "code": "448248006",
            "description": "Malignant neoplasm of axial suprasellar region of brain",
            "attributes": null
          },
          {
            "code": "448250003",
            "description": "Malignant teratoma of pineal region",
            "attributes": null
          },
          {
            "code": "448863000",
            "description": "Malignant epithelial neoplasm of pineal gland",
            "attributes": null
          },
          {
            "code": "448989001",
            "description": "Malignant epithelial neoplasm of brain",
            "attributes": null
          },
          {
            "code": "449253005",
            "description": "Malignant epithelial neoplasm of hypothalamus",
            "attributes": null
          },
          {
            "code": "449420002",
            "description": "Malignant neoplasm of cerebellum",
            "attributes": null
          },
          {
            "code": "539391000000105",
            "description": "Malignant neoplasm of cerebrum NOS",
            "attributes": null
          },
          {
            "code": "539511000000109",
            "description": "Malignant neoplasm of temporal lobe NOS",
            "attributes": null
          },
          {
            "code": "539521000000103",
            "description": "Malignant neoplasm of cerebral ventricle NOS",
            "attributes": null
          },
          {
            "code": "539531000000101",
            "description": "Malignant neoplasm of brainstem NOS",
            "attributes": null
          },
          {
            "code": "566041000000100",
            "description": "Malignant neoplasm of pituitary gland or craniopharyngeal duct NOS",
            "attributes": null
          },
          {
            "code": "67771000119102",
            "description": "Grade 2 astrocytoma of brain",
            "attributes": null
          },
          {
            "code": "682221000119103",
            "description": "Primary anaplastic astrocytoma of cerebrum",
            "attributes": null
          },
          {
            "code": "682231000119100",
            "description": "Primary anaplastic astrocytoma of frontal lobe",
            "attributes": null
          },
          {
            "code": "682241000119109",
            "description": "Primary anaplastic astrocytoma of occipital lobe",
            "attributes": null
          },
          {
            "code": "682251000119106",
            "description": "Primary anaplastic astrocytoma of parietal lobe",
            "attributes": null
          },
          {
            "code": "682261000119108",
            "description": "Primary anaplastic astrocytoma of temporal lobe",
            "attributes": null
          },
          {
            "code": "682441000119105",
            "description": "Primary astrocytoma of cerebral ventricle",
            "attributes": null
          },
          {
            "code": "682451000119107",
            "description": "Primary astrocytoma of frontal lobe",
            "attributes": null
          },
          {
            "code": "682461000119109",
            "description": "Primary astrocytoma of occipital lobe",
            "attributes": null
          },
          {
            "code": "682471000119103",
            "description": "Primary astrocytoma of parietal lobe",
            "attributes": null
          },
          {
            "code": "682481000119100",
            "description": "Primary astrocytoma of temporal lobe",
            "attributes": null
          },
          {
            "code": "683761000119107",
            "description": "Primary ependymoma of brain ventricle",
            "attributes": null
          },
          {
            "code": "683771000119101",
            "description": "Primary ependymoma of frontal lobe",
            "attributes": null
          },
          {
            "code": "683791000119100",
            "description": "Primary ependymoma of parietal lobe",
            "attributes": null
          },
          {
            "code": "684901000119107",
            "description": "Primary glioblastoma multiforme of cerebrum",
            "attributes": null
          },
          {
            "code": "684911000119105",
            "description": "Primary glioblastoma multiforme of frontal lobe",
            "attributes": null
          },
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