[
  {
    "phenotype_id": "PH2321",
    "phenotype_version_id": 5463,
    "name": "Chemotherapy non-drug concept codes",
    "definition": "This codelist was taken from [OpenCodelists](https://www.opencodelists.org/), created by [OpenSAFELY](https://www.opensafely.org/). We recommend viewing this Phenotype on the OpenCodelist website to view the most recent version.\n\n\nTaken from the `CHEMO_COD` refset published by NHSD. Contains public sector information licensed under the UK Open Government Licence v3\\.0 (https://www.nationalarchives.gov.uk/doc/open\\-government\\-licence/version/3/).\n\n\n© University of Oxford for the Bennett Institute for Applied Data Science 2025\\. This work may be copied freely for non\\-commercial research and study.\n\n",
    "implementation": null,
    "publications": null,
    "validation": null,
    "citation_requirements": null,
    "created": "2026-01-26T22:06:15.605851Z",
    "author": "NHSD Primary Care Domain Refsets",
    "collections": [
      {
        "name": "OpenCodelist",
        "value": 31
      },
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": {
      "id": 1,
      "slug": "opensafely",
      "name": "OpenSAFELY"
    },
    "world_access": 1,
    "updated": "2026-01-26T22:06:20.338109Z",
    "references": [],
    "signed_off": [],
    "methodology": "This codelist was imported automatically. The following codes were not found in the SNOMED CT (UK Clinical Edition) dictionary and so excluded from this codelist: 42652011000001100, 42638411000001107, 42577111000001105, 42598211000001107\\.\n\n\nThis may be because this codelist contains both clinical terms and medications. In which case you may need to create another codelist for the missing clinical/medication codes.\n\n",
    "coding_system": [
      {
        "name": "SNOMED  CT codes",
        "value": 9
      }
    ],
    "open_codelist_id": "nhsd-primary-care-domain-refsets/chemo_cod",
    "source_reference": "https://www.opencodelists.org/codelist/nhsd-primary-care-domain-refsets/chemo_cod/20250912",
    "concept_information": [
      {
        "concept_id": 5640,
        "concept_version_id": 13125,
        "concept_name": "nhsd-primary-care-domain-refsets/chemo_cod/20250912",
        "coding_system": {
          "id": 9,
          "name": "SNOMED  CT codes",
          "description": "SNOMED CT codes"
        },
        "phenotype_id": "PH2321",
        "phenotype_version_id": 5463,
        "phenotype_name": "Chemotherapy non-drug concept codes",
        "code_attribute_header": [],
        "codes": [
          {
            "code": "10075000",
            "description": "Photochemotherapy with tar and ultraviolet B",
            "attributes": null
          },
          {
            "code": "103081004",
            "description": "Immunodeficiency secondary to chemotherapy",
            "attributes": null
          },
          {
            "code": "1035621000000102",
            "description": "Resistance to antineoplastic drug",
            "attributes": null
          },
          {
            "code": "1035631000000100",
            "description": "Resistance to antineoplastic drugs",
            "attributes": null
          },
          {
            "code": "1064281000000106",
            "description": "Cancer chemotherapy management plan",
            "attributes": null
          },
          {
            "code": "109256003",
            "description": "Mucositis following chemotherapy",
            "attributes": null
          },
          {
            "code": "110264005",
            "description": "Effects of chemotherapy",
            "attributes": null
          },
          {
            "code": "1141994004",
            "description": "Rituximab, cyclophosphamide, etoposide, vincristine, prednisone antineoplastic chemotherapy regimen",
            "attributes": null
          },
          {
            "code": "1148692008",
            "description": "Radiation therapy following chemotherapy",
            "attributes": null
          },
          {
            "code": "1167461000000101",
            "description": "Intra-arterial injection of antineoplastic agent into left ophthalmic artery using fluoroscopic guidance with contrast",
            "attributes": null
          },
          {
            "code": "1167471000000108",
            "description": "Intra-arterial injection of antineoplastic agent into right ophthalmic artery using fluoroscopic guidance with contrast",
            "attributes": null
          },
          {
            "code": "1167481000000105",
            "description": "Intra-arterial injection of antineoplastic agent into bilateral ophthalmic arteries using fluoroscopic guidance with contrast",
            "attributes": null
          },
          {
            "code": "1172516002",
            "description": "High-dose chemotherapy with stem cell transplant",
            "attributes": null
          },
          {
            "code": "118791000119106",
            "description": "Aplastic anemia caused by antineoplastic agent",
            "attributes": null
          },
          {
            "code": "118911000119104",
            "description": "Long-term current use of lenalidomide",
            "attributes": null
          },
          {
            "code": "1197521004",
            "description": "Inflammation of mucous membrane due to and following chemotherapy",
            "attributes": null
          },
          {
            "code": "1197527000",
            "description": "Ulcerative inflammation of oral mucous membrane due to and following administration of antineoplastic agent",
            "attributes": null
          },
          {
            "code": "12149006",
            "description": "Chemotherapy administration, subcutaneous, with local anesthesia",
            "attributes": null
          },
          {
            "code": "1217525002",
            "description": "Injection of antineoplastic agent into neoplasm of brain tissue",
            "attributes": null
          },
          {
            "code": "125211000119106",
            "description": "History of antineoplastic chemotherapy",
            "attributes": null
          },
          {
            "code": "1254741007",
            "description": "Intensification antineoplastic therapy regimen",
            "attributes": null
          },
          {
            "code": "1254742000",
            "description": "Delayed intensification antineoplastic therapy regimen",
            "attributes": null
          },
          {
            "code": "1255831008",
            "description": "Chemotherapy for malignant neoplastic disease using targeted agent",
            "attributes": null
          },
          {
            "code": "1255834000",
            "description": "Administration of antineoplastic chemotherapy into peritoneal cavity",
            "attributes": null
          },
          {
            "code": "1255904006",
            "description": "Administration of palliative antineoplastic agent",
            "attributes": null
          },
          {
            "code": "1259200004",
            "description": "Neoadjuvant antineoplastic chemotherapy",
            "attributes": null
          },
          {
            "code": "1264382006",
            "description": "Follow-up for combined therapy of radiation therapy and chemotherapy",
            "attributes": null
          },
          {
            "code": "1264383001",
            "description": "Follow-up for combined therapy of surgery and chemotherapy",
            "attributes": null
          },
          {
            "code": "1264385008",
            "description": "Follow-up for combined therapy of surgery, radiation therapy, and chemotherapy",
            "attributes": null
          },
          {
            "code": "1279827005",
            "description": "Neoadjuvant antineoplastic therapy procedure prior to surgery",
            "attributes": null
          },
          {
            "code": "1287761004",
            "description": "Arsenic therapy",
            "attributes": null
          },
          {
            "code": "1287762006",
            "description": "Arsenic compound therapy",
            "attributes": null
          },
          {
            "code": "1290226008",
            "description": "Administration of antineoplastic agent via intravenous route",
            "attributes": null
          },
          {
            "code": "1290228009",
            "description": "Administration of antineoplastic agent via subcutaneous route",
            "attributes": null
          },
          {
            "code": "129663002",
            "description": "Neurotoxicity caused by vincristine",
            "attributes": null
          },
          {
            "code": "129665009",
            "description": "Neurotoxicity caused by L-asparaginase",
            "attributes": null
          },
          {
            "code": "1362501000000105",
            "description": "Laparoscopic administration of pressurised aerosol antineoplastic agent into peritoneal cavity",
            "attributes": null
          },
          {
            "code": "136281000119109",
            "description": "Anemia caused by antineoplastic agent",
            "attributes": null
          },
          {
            "code": "138918002",
            "description": "H/O: chemotherapy",
            "attributes": null
          },
          {
            "code": "146562008",
            "description": "External beam - surgery with chemotherapy",
            "attributes": null
          },
          {
            "code": "146563003",
            "description": "External beam with chemotherapy",
            "attributes": null
          },
          {
            "code": "146623009",
            "description": "Radiomimetic chemotherapy",
            "attributes": null
          },
          {
            "code": "146624003",
            "description": "Radiochemotherapy: local infiltration",
            "attributes": null
          },
          {
            "code": "146625002",
            "description": "Radiochemotherapy: to stop spread",
            "attributes": null
          },
          {
            "code": "146626001",
            "description": "Radiochemotherapy: oral route",
            "attributes": null
          },
          {
            "code": "146627005",
            "description": "Radiochemotherapy: IV route",
            "attributes": null
          },
          {
            "code": "146628000",
            "description": "Radiochemotherapy: for immunosuppression",
            "attributes": null
          },
          {
            "code": "146629008",
            "description": "Radiochemotherapy: local artery",
            "attributes": null
          },
          {
            "code": "146630003",
            "description": "Radiochemotherapy: into cavity",
            "attributes": null
          },
          {
            "code": "146631004",
            "description": "Radiochemotherapy NOS",
            "attributes": null
          },
          {
            "code": "147696002",
            "description": "Prophylactic chemotherapy",
            "attributes": null
          },
          {
            "code": "147704001",
            "description": "Prophylactic chemotherapy NOS",
            "attributes": null
          },
          {
            "code": "14836003",
            "description": "Radiation recall syndrome",
            "attributes": null
          },
          {
            "code": "150415003",
            "description": "Chemotherapy",
            "attributes": null
          },
          {
            "code": "150466008",
            "description": "Intravenous chemotherapy",
            "attributes": null
          },
          {
            "code": "151250002",
            "description": "Oral chemotherapy (& cytotoxic)",
            "attributes": null
          },
          {
            "code": "151261005",
            "description": "Ambulatory chemotherapy",
            "attributes": null
          },
          {
            "code": "151608008",
            "description": "Convalescence after chemotherapy",
            "attributes": null
          },
          {
            "code": "151882008",
            "description": "Chemotherapy follow-up",
            "attributes": null
          },
          {
            "code": "161653008",
            "description": "History of chemotherapy",
            "attributes": null
          },
          {
            "code": "1680000",
            "description": "Secondary chemoprophylaxis",
            "attributes": null
          },
          {
            "code": "169335009",
            "description": "External beam radiotherapy with surgery and chemotherapy",
            "attributes": null
          },
          {
            "code": "169336005",
            "description": "External beam radiation therapy with chemotherapy",
            "attributes": null
          },
          {
            "code": "169396008",
            "description": "Radiomimetic chemotherapy",
            "attributes": null
          },
          {
            "code": "169397004",
            "description": "Radiochemotherapy by local infiltration",
            "attributes": null
          },
          {
            "code": "169398009",
            "description": "Radiochemotherapy: to stop spread",
            "attributes": null
          },
          {
            "code": "169399001",
            "description": "Radiochemotherapy via oral route",
            "attributes": null
          },
          {
            "code": "169400008",
            "description": "Radiochemotherapy via intravenous route",
            "attributes": null
          },
          {
            "code": "169401007",
            "description": "Radiochemotherapy for immunosuppression",
            "attributes": null
          },
          {
            "code": "169402000",
            "description": "Intraarterial radiochemotherapy",
            "attributes": null
          },
          {
            "code": "169403005",
            "description": "Intracavitary radiochemotherapy",
            "attributes": null
          },
          {
            "code": "169404004",
            "description": "Radiochemotherapy NOS",
            "attributes": null
          },
          {
            "code": "170445004",
            "description": "Prophylaxis: [chemotherapy] or [drug]",
            "attributes": null
          },
          {
            "code": "170452002",
            "description": "Prophylactic chemotherapy NOS",
            "attributes": null
          },
          {
            "code": "171765004",
            "description": "Intrathecal injection of chemotherapeutic agent",
            "attributes": null
          },
          {
            "code": "180180003",
            "description": "Continuous infusion of chemotherapy",
            "attributes": null
          },
          {
            "code": "180222003",
            "description": "Intravenous therapy: [chemo-] or [drug]",
            "attributes": null
          },
          {
            "code": "180243002",
            "description": "Intramuscular therapy: [chemo-] or [drug]",
            "attributes": null
          },
          {
            "code": "182967006",
            "description": "Oral chemotherapy (& cytotoxic)",
            "attributes": null
          },
          {
            "code": "182973007",
            "description": "Chemotherapy",
            "attributes": null
          },
          {
            "code": "182974001",
            "description": "Cancer chemotherapy",
            "attributes": null
          },
          {
            "code": "182983006",
            "description": "Ambulatory chemotherapy",
            "attributes": null
          },
          {
            "code": "183373009",
            "description": "Convalescence after chemotherapy",
            "attributes": null
          },
          {
            "code": "183651009",
            "description": "Chemotherapy follow-up",
            "attributes": null
          },
          {
            "code": "18846006",
            "description": "Chemotherapy-induced nausea and vomiting",
            "attributes": null
          },
          {
            "code": "198551000000104",
            "description": "Chemotherapy started",
            "attributes": null
          },
          {
            "code": "212511004",
            "description": "Antineoplastic antibiotic poisoning NOS",
            "attributes": null
          },
          {
            "code": "213871000000100",
            "description": "Chemotherapy started",
            "attributes": null
          },
          {
            "code": "213881000000103",
            "description": "Chemotherapy started",
            "attributes": null
          },
          {
            "code": "218326006",
            "description": "Adverse reaction caused by antineoplastic antibiotics",
            "attributes": null
          },
          {
            "code": "218327002",
            "description": "Adverse reaction to actinomycin D",
            "attributes": null
          },
          {
            "code": "218328007",
            "description": "Adverse reaction to bleomycin",
            "attributes": null
          },
          {
            "code": "218329004",
            "description": "Adverse reaction to doxorubicin hydrochloride",
            "attributes": null
          },
          {
            "code": "218330009",
            "description": "Adverse reaction to mitomycin",
            "attributes": null
          },
          {
            "code": "218331008",
            "description": "Adverse reaction to plicamycin",
            "attributes": null
          },
          {
            "code": "218333006",
            "description": "Adverse reaction to antineoplastic antibiotics NOS",
            "attributes": null
          },
          {
            "code": "218505007",
            "description": "Adverse reaction to busulfan",
            "attributes": null
          },
          {
            "code": "218506008",
            "description": "Adverse reaction to carmustine",
            "attributes": null
          },
          {
            "code": "218507004",
            "description": "Adverse reaction to chlorambucil",
            "attributes": null
          },
          {
            "code": "218508009",
            "description": "Adverse reaction to cyclophosphamide",
            "attributes": null
          },
          {
            "code": "218509001",
            "description": "Adverse reaction to estramustine phosphate",
            "attributes": null
          },
          {
            "code": "218510006",
            "description": "Adverse reaction to lomustine",
            "attributes": null
          },
          {
            "code": "218511005",
            "description": "Adverse reaction to melphalan",
            "attributes": null
          },
          {
            "code": "218512003",
            "description": "Adverse reaction to mustine hydrochloride",
            "attributes": null
          },
          {
            "code": "218513008",
            "description": "Adverse reaction to thiotepa",
            "attributes": null
          },
          {
            "code": "218515001",
            "description": "Adverse reaction to cytarabine",
            "attributes": null
          },
          {
            "code": "218517009",
            "description": "Adverse reaction to mercaptopurine",
            "attributes": null
          },
          {
            "code": "218519007",
            "description": "Adverse reaction to thioguanine",
            "attributes": null
          },
          {
            "code": "218520001",
            "description": "Adverse reaction to etoposide",
            "attributes": null
          },
          {
            "code": "218521002",
            "description": "Adverse reaction to vinblastine sulfate",
            "attributes": null
          },
          {
            "code": "218522009",
            "description": "Adverse reaction to vincristine sulfate",
            "attributes": null
          },
          {
            "code": "218523004",
            "description": "Adverse reaction to carboplatin",
            "attributes": null
          },
          {
            "code": "218524005",
            "description": "Adverse reaction to cisplatin",
            "attributes": null
          },
          {
            "code": "218525006",
            "description": "Adverse reaction to hydroxyurea",
            "attributes": null
          },
          {
            "code": "218526007",
            "description": "Adverse reaction to mitozantrone",
            "attributes": null
          },
          {
            "code": "218527003",
            "description": "Adverse reaction to procarbazine",
            "attributes": null
          },
          {
            "code": "218528008",
            "description": "Adverse reaction to razoxane",
            "attributes": null
          },
          {
            "code": "222985009",
            "description": "[X]Antineoplastic antimetabolites causing adverse effects in therapeutic use",
            "attributes": null
          },
          {
            "code": "222986005",
            "description": "[X]Antineoplastic natural products causing adverse effects in therapeutic use",
            "attributes": null
          },
          {
            "code": "222987001",
            "description": "[X]Other antineoplastic drugs causing adverse effects in therapeutic use",
            "attributes": null
          },
          {
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            "description": "Photochemotherapy",
            "attributes": null
          },
          {
            "code": "22638002",
            "description": "Photochemotherapy with tar and petrolatum",
            "attributes": null
          },
          {
            "code": "22733003",
            "description": "Chemotherapy for non-malignant neoplasm",
            "attributes": null
          },
          {
            "code": "230857009",
            "description": "Injection of chemotherapeutic substance into subcutaneous reservoir",
            "attributes": null
          },
          {
            "code": "232681000000103",
            "description": "Chemotherapy delivery",
            "attributes": null
          },
          {
            "code": "235331000000103",
            "description": "Delivery of oral chemotherapy for neoplasm",
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          },
          {
            "code": "235391000000102",
            "description": "Delivery of chemotherapy for neoplasm",
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          },
          {
            "code": "236084000",
            "description": "Chemotherapy sickness",
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          },
          {
            "code": "238519000",
            "description": "Photochemotherapy reaction",
            "attributes": null
          },
          {
            "code": "238811000000106",
            "description": "Delivery of oral chemotherapy for neoplasm NOS",
            "attributes": null
          },
          {
            "code": "238831000000103",
            "description": "Delivery of exclusively oral chemotherapy for neoplasm",
            "attributes": null
          },
          {
            "code": "238841000000107",
            "description": "Delivery of complex chemotherapy for neoplasm including prolonged infusional treatment at first attendance",
            "attributes": null
          },
          {
            "code": "238851000000105",
            "description": "Delivery of complex parenteral chemotherapy for neoplasm at first attendance",
            "attributes": null
          },
          {
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            "description": "Delivery of simple parenteral chemotherapy for neoplasm at first attendance",
            "attributes": null
          },
          {
            "code": "238871000000101",
            "description": "Delivery of chemotherapy for neoplasm NOS",
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          },
          {
            "code": "239071000000100",
            "description": "Delivery of subsequent element of cycle of chemotherapy for neoplasm",
            "attributes": null
          },
          {
            "code": "239081000000103",
            "description": "Other specified delivery of chemotherapy for neoplasm",
            "attributes": null
          },
          {
            "code": "239091000000101",
            "description": "Other specified delivery of oral chemotherapy for neoplasm",
            "attributes": null
          },
          {
            "code": "240251000000107",
            "description": "Problems following chemotherapy",
            "attributes": null
          },
          {
            "code": "243571000000108",
            "description": "Symptoms due to chemotherapy",
            "attributes": null
          },
          {
            "code": "25081000000105",
            "description": "Chemotherapy changed - acute chemotherapy toxicity",
            "attributes": null
          },
          {
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            "description": "Chemotherapy changed - patient choice",
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          },
          {
            "code": "25521000000102",
            "description": "Chemotherapy changed - progressive disease during chemotherapy",
            "attributes": null
          },
          {
            "code": "25531000000100",
            "description": "Chemotherapy changed - technical or organisational problems",
            "attributes": null
          },
          {
            "code": "262502001",
            "description": "Post-chemotherapy",
            "attributes": null
          },
          {
            "code": "265760000",
            "description": "Intravenous chemotherapy",
            "attributes": null
          },
          {
            "code": "265761001",
            "description": "Intramuscular chemotherapy",
            "attributes": null
          },
          {
            "code": "265762008",
            "description": "Subcutaneous chemotherapy",
            "attributes": null
          },
          {
            "code": "266719004",
            "description": "Oral chemotherapy",
            "attributes": null
          },
          {
            "code": "267901000000108",
            "description": "Delivery of chemotherapy for neoplasm",
            "attributes": null
          },
          {
            "code": "267911000000105",
            "description": "Delivery of complex chemotherapy for neoplasm including prolonged infusional treatment at first attendance",
            "attributes": null
          },
          {
            "code": "267921000000104",
            "description": "Delivery of complex parenteral chemotherapy for neoplasm at first attendance",
            "attributes": null
          },
          {
            "code": "267931000000102",
            "description": "Delivery of simple parenteral chemotherapy for neoplasm at first attendance",
            "attributes": null
          },
          {
            "code": "267941000000106",
            "description": "Delivery of subsequent element of cycle of chemotherapy for neoplasm",
            "attributes": null
          },
          {
            "code": "267951000000109",
            "description": "Other specified delivery of chemotherapy for neoplasm",
            "attributes": null
          },
          {
            "code": "267961000000107",
            "description": "Delivery of chemotherapy for neoplasm NOS",
            "attributes": null
          },
          {
            "code": "267971000000100",
            "description": "Delivery of oral chemotherapy for neoplasm",
            "attributes": null
          },
          {
            "code": "267981000000103",
            "description": "Delivery of exclusively oral chemotherapy for neoplasm",
            "attributes": null
          },
          {
            "code": "267991000000101",
            "description": "Other specified delivery of oral chemotherapy for neoplasm",
            "attributes": null
          },
          {
            "code": "268001000000105",
            "description": "Delivery of oral chemotherapy for neoplasm NOS",
            "attributes": null
          },
          {
            "code": "268500004",
            "description": "Administration of prophylactic chemotherapy",
            "attributes": null
          },
          {
            "code": "282571000000106",
            "description": "Combined photochemotherapy and ultraviolet A light therapy to skin",
            "attributes": null
          },
          {
            "code": "282581000000108",
            "description": "Combined photochemotherapy and ultraviolet B light therapy to skin",
            "attributes": null
          },
          {
            "code": "288108006",
            "description": "Cytotoxic drug therapy NOS",
            "attributes": null
          },
          {
            "code": "290631006",
            "description": "Triazene antineoplastic poisoning",
            "attributes": null
          },
          {
            "code": "290721000000104",
            "description": "Combined photochemotherapy and ultraviolet A light therapy to skin",
            "attributes": null
          },
          {
            "code": "290731000000102",
            "description": "Combined photochemotherapy and ultraviolet B light therapy to skin",
            "attributes": null
          },
          {
            "code": "292190002",
            "description": "Aldesleukin adverse reaction",
            "attributes": null
          },
          {
            "code": "292196008",
            "description": "Antineoplastic adverse reaction",
            "attributes": null
          },
          {
            "code": "292197004",
            "description": "Alkylating drug adverse reaction",
            "attributes": null
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