[
  {
    "phenotype_id": "PH2348",
    "phenotype_version_id": 5566,
    "name": "Chronic liver disease (CLD) codes",
    "definition": "This codelist was taken from [OpenCodelists](https://www.opencodelists.org/), created by [OpenSAFELY](https://www.opensafely.org/). We recommend viewing this Phenotype on the OpenCodelist website to view the most recent version.\n\n\nTaken from the `CLDATRISK1_COD` refset published by NHSD. Contains public sector information licensed under the UK Open Government Licence v3\\.0 (https://www.nationalarchives.gov.uk/doc/open\\-government\\-licence/version/3/).\n\n\n© University of Oxford for the Bennett Institute for Applied Data Science 2025\\. This work may be copied freely for non\\-commercial research and study.\n\n",
    "implementation": null,
    "publications": null,
    "validation": null,
    "citation_requirements": null,
    "created": "2026-01-26T22:08:56.768071Z",
    "author": "NHSD Primary Care Domain Refsets",
    "collections": [
      {
        "name": "OpenCodelist",
        "value": 31
      },
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": {
      "id": 1,
      "slug": "opensafely",
      "name": "OpenSAFELY"
    },
    "world_access": 1,
    "updated": "2026-01-26T22:09:07.309649Z",
    "references": [
      {
        "url": "https://digital.nhs.uk/data-and-information/data-collections-and-data-sets/data-collections/quality-and-outcomes-framework-qof/quality-and-outcome-framework-qof-business-rules/primary-care-domain-reference-set-portal",
        "title": "Primary Care Domain Reference Set Portal"
      }
    ],
    "signed_off": [],
    "methodology": "",
    "coding_system": [
      {
        "name": "SNOMED  CT codes",
        "value": 9
      }
    ],
    "open_codelist_id": "nhsd-primary-care-domain-refsets/cldatrisk1_cod",
    "source_reference": "https://www.opencodelists.org/codelist/nhsd-primary-care-domain-refsets/cldatrisk1_cod/20250912",
    "concept_information": [
      {
        "concept_id": 5743,
        "concept_version_id": 13228,
        "concept_name": "nhsd-primary-care-domain-refsets/cldatrisk1_cod/20250912",
        "coding_system": {
          "id": 9,
          "name": "SNOMED  CT codes",
          "description": "SNOMED CT codes"
        },
        "phenotype_id": "PH2348",
        "phenotype_version_id": 5566,
        "phenotype_name": "Chronic liver disease (CLD) codes",
        "code_attribute_header": [],
        "codes": [
          {
            "code": "1003567000",
            "description": "Agenesis of bile duct",
            "attributes": null
          },
          {
            "code": "1010616001",
            "description": "Cirrhosis of liver due to classical cystic fibrosis",
            "attributes": null
          },
          {
            "code": "10295004",
            "description": "Chronic viral hepatitis",
            "attributes": null
          },
          {
            "code": "103611000119102",
            "description": "Cirrhosis of liver due to hepatitis B",
            "attributes": null
          },
          {
            "code": "10690671000119109",
            "description": "Stage 3 hepatic fibrosis",
            "attributes": null
          },
          {
            "code": "1082601000119104",
            "description": "Ascites due to alcoholic cirrhosis",
            "attributes": null
          },
          {
            "code": "1092801000119102",
            "description": "Hepatic ascites co-occurrent with chronic active hepatitis due to toxic liver disease",
            "attributes": null
          },
          {
            "code": "109819003",
            "description": "Obstructive biliary cirrhosis",
            "attributes": null
          },
          {
            "code": "111370006",
            "description": "Cirrhosis of liver not due to alcohol",
            "attributes": null
          },
          {
            "code": "1116000",
            "description": "Chronic aggressive type B viral hepatitis",
            "attributes": null
          },
          {
            "code": "1155841005",
            "description": "Progressive familial intrahepatic cholestasis type 2",
            "attributes": null
          },
          {
            "code": "1155913007",
            "description": "Progressive familial intrahepatic cholestasis type 1",
            "attributes": null
          },
          {
            "code": "1156870007",
            "description": "Absence of liver",
            "attributes": null
          },
          {
            "code": "1186865008",
            "description": "Progressive familial intrahepatic cholestasis type 3",
            "attributes": null
          },
          {
            "code": "1197150002",
            "description": "Recurrent hepatitis C virus induced liver disease following liver transplant",
            "attributes": null
          },
          {
            "code": "1197694007",
            "description": "Esophageal varices with bleeding due to toxic liver disease",
            "attributes": null
          },
          {
            "code": "1197696009",
            "description": "Esophageal varices with bleeding due to hepatic fibrosis",
            "attributes": null
          },
          {
            "code": "1197697000",
            "description": "Esophageal varices with bleeding due to primary biliary cholangitis",
            "attributes": null
          },
          {
            "code": "1197698005",
            "description": "Esophageal varices with bleeding due to alcoholic liver disease",
            "attributes": null
          },
          {
            "code": "1197700001",
            "description": "Esophageal varices with bleeding due to autoimmune hepatitis",
            "attributes": null
          },
          {
            "code": "1197704005",
            "description": "Autoantibody negative autoimmune hepatitis",
            "attributes": null
          },
          {
            "code": "1197736003",
            "description": "Chronic hepatic failure due to portosystemic shunt",
            "attributes": null
          },
          {
            "code": "12224501000119108",
            "description": "Infection of transplanted liver",
            "attributes": null
          },
          {
            "code": "1230291009",
            "description": "Primary biliary cholangitis and/or primary sclerosing cholangitis and autoimmune hepatitis overlap syndrome",
            "attributes": null
          },
          {
            "code": "1230342001",
            "description": "Hepatitis B reinfection following transplantation of liver",
            "attributes": null
          },
          {
            "code": "1234778004",
            "description": "Steatohepatitis caused by ethanol",
            "attributes": null
          },
          {
            "code": "123604002",
            "description": "Toxic cirrhosis",
            "attributes": null
          },
          {
            "code": "123605001",
            "description": "Nutritional cirrhosis",
            "attributes": null
          },
          {
            "code": "123606000",
            "description": "Cholangiolitic cirrhosis",
            "attributes": null
          },
          {
            "code": "12368000",
            "description": "Secondary biliary cirrhosis",
            "attributes": null
          },
          {
            "code": "123716002",
            "description": "Latent cirrhosis",
            "attributes": null
          },
          {
            "code": "123717006",
            "description": "Advanced cirrhosis",
            "attributes": null
          },
          {
            "code": "1259465009",
            "description": "Dementia due to hepatic failure",
            "attributes": null
          },
          {
            "code": "1263507006",
            "description": "Myoclonic disorder due to hepatic failure",
            "attributes": null
          },
          {
            "code": "1268390002",
            "description": "Metastatic undifferentiated carcinoma to liver and intrahepatic biliary tract",
            "attributes": null
          },
          {
            "code": "128072003",
            "description": "Acquired portal-systemic shunt due to cirrhosis",
            "attributes": null
          },
          {
            "code": "128302006",
            "description": "Chronic hepatitis C",
            "attributes": null
          },
          {
            "code": "1287007",
            "description": "Congenital absence of bile duct",
            "attributes": null
          },
          {
            "code": "15999000",
            "description": "Mixed micro and macronodular cirrhosis",
            "attributes": null
          },
          {
            "code": "16070004",
            "description": "Syphilitic cirrhosis",
            "attributes": null
          },
          {
            "code": "16098491000119109",
            "description": "Chronic autoimmune hepatitis",
            "attributes": null
          },
          {
            "code": "161671001",
            "description": "History of liver recipient",
            "attributes": null
          },
          {
            "code": "16623921000119105",
            "description": "Viral hepatitis C in mother during pregnancy",
            "attributes": null
          },
          {
            "code": "16859701000119109",
            "description": "Chronic hepatitis B during pregnancy",
            "attributes": null
          },
          {
            "code": "174425003",
            "description": "Orthotopic liver transplant",
            "attributes": null
          },
          {
            "code": "174426002",
            "description": "Heterotopic liver transplant",
            "attributes": null
          },
          {
            "code": "174427006",
            "description": "Replacement of previous liver transplant",
            "attributes": null
          },
          {
            "code": "1761006",
            "description": "Biliary cirrhosis",
            "attributes": null
          },
          {
            "code": "18027006",
            "description": "Transplantation of liver",
            "attributes": null
          },
          {
            "code": "186639003",
            "description": "Chronic viral hepatitis B without delta-agent",
            "attributes": null
          },
          {
            "code": "19682006",
            "description": "Lupus hepatitis",
            "attributes": null
          },
          {
            "code": "197279005",
            "description": "Cirrhosis and chronic liver disease",
            "attributes": null
          },
          {
            "code": "197284004",
            "description": "Chronic active hepatitis",
            "attributes": null
          },
          {
            "code": "197286002",
            "description": "Recurrent hepatitis",
            "attributes": null
          },
          {
            "code": "197291001",
            "description": "Unilobular portal cirrhosis",
            "attributes": null
          },
          {
            "code": "197293003",
            "description": "Diffuse nodular cirrhosis",
            "attributes": null
          },
          {
            "code": "197294009",
            "description": "Fatty portal cirrhosis",
            "attributes": null
          },
          {
            "code": "197296006",
            "description": "Capsular portal cirrhosis",
            "attributes": null
          },
          {
            "code": "197299004",
            "description": "Pigmentary portal cirrhosis",
            "attributes": null
          },
          {
            "code": "197301006",
            "description": "Toxic portal cirrhosis",
            "attributes": null
          },
          {
            "code": "197303009",
            "description": "Bacterial portal cirrhosis",
            "attributes": null
          },
          {
            "code": "197305002",
            "description": "Syphilitic portal cirrhosis",
            "attributes": null
          },
          {
            "code": "197306001",
            "description": "Zooparasitic portal cirrhosis",
            "attributes": null
          },
          {
            "code": "197310003",
            "description": "Biliary cirrhosis of children",
            "attributes": null
          },
          {
            "code": "197359004",
            "description": "Toxic liver disease with chronic persistent hepatitis",
            "attributes": null
          },
          {
            "code": "197360009",
            "description": "Toxic liver disease with chronic lobular hepatitis",
            "attributes": null
          },
          {
            "code": "197361008",
            "description": "Toxic liver disease with chronic active hepatitis",
            "attributes": null
          },
          {
            "code": "197362001",
            "description": "Toxic liver disease with fibrosis and cirrhosis of liver",
            "attributes": null
          },
          {
            "code": "197553002",
            "description": "[X]Other and unspecified cirrhosis of liver",
            "attributes": null
          },
          {
            "code": "19943007",
            "description": "Cirrhosis of liver",
            "attributes": null
          },
          {
            "code": "204781002",
            "description": "Congenital absence of hepatic ducts",
            "attributes": null
          },
          {
            "code": "204782009",
            "description": "Atresia of hepatic ducts",
            "attributes": null
          },
          {
            "code": "213153001",
            "description": "Liver transplant failure and rejection",
            "attributes": null
          },
          {
            "code": "21861000",
            "description": "Micronodular cirrhosis",
            "attributes": null
          },
          {
            "code": "235458006",
            "description": "Exploration of liver transplant",
            "attributes": null
          },
          {
            "code": "235869004",
            "description": "Chronic viral hepatitis B with hepatitis D",
            "attributes": null
          },
          {
            "code": "235870003",
            "description": "Chronic non-A non-B hepatitis",
            "attributes": null
          },
          {
            "code": "235886005",
            "description": "Chronic hepatic failure",
            "attributes": null
          },
          {
            "code": "235889003",
            "description": "Drug-induced chronic hepatitis",
            "attributes": null
          },
          {
            "code": "235894003",
            "description": "Portal cirrhosis",
            "attributes": null
          },
          {
            "code": "235895002",
            "description": "Laennec's cirrhosis, non-alcoholic",
            "attributes": null
          },
          {
            "code": "235896001",
            "description": "Infectious cirrhosis",
            "attributes": null
          },
          {
            "code": "235897005",
            "description": "Hypoxia-associated cirrhosis",
            "attributes": null
          },
          {
            "code": "235899008",
            "description": "Hepatic sclerosis",
            "attributes": null
          },
          {
            "code": "235901004",
            "description": "Hepatic fibrosis with hepatic sclerosis",
            "attributes": null
          },
          {
            "code": "235902006",
            "description": "Intrahepatic phlebosclerosis and fibrosis",
            "attributes": null
          },
          {
            "code": "235910007",
            "description": "Liver transplant disorder",
            "attributes": null
          },
          {
            "code": "235911006",
            "description": "Liver transplant rejection",
            "attributes": null
          },
          {
            "code": "235912004",
            "description": "Liver transplant failure",
            "attributes": null
          },
          {
            "code": "235916001",
            "description": "Ichthyosis congenita with biliary atresia",
            "attributes": null
          },
          {
            "code": "253807009",
            "description": "Intrahepatic biliary atresia",
            "attributes": null
          },
          {
            "code": "266468003",
            "description": "Cirrhosis - non-alcoholic",
            "attributes": null
          },
          {
            "code": "266469006",
            "description": "Multilobular portal cirrhosis",
            "attributes": null
          },
          {
            "code": "266470007",
            "description": "Cardiac portal cirrhosis",
            "attributes": null
          },
          {
            "code": "266471006",
            "description": "Juvenile portal cirrhosis",
            "attributes": null
          },
          {
            "code": "271440004",
            "description": "Cirrhosis secondary to cholestasis",
            "attributes": null
          },
          {
            "code": "27156006",
            "description": "Posthepatitic cirrhosis",
            "attributes": null
          },
          {
            "code": "27280000",
            "description": "Liver transplant with recipient hepatectomy",
            "attributes": null
          },
          {
            "code": "28009009",
            "description": "Liver transplant without recipient hepatectomy",
            "attributes": null
          },
          {
            "code": "307757001",
            "description": "Chronic alcoholic hepatitis",
            "attributes": null
          },
          {
            "code": "308129003",
            "description": "Esophageal varices in cirrhosis of the liver",
            "attributes": null
          },
          {
            "code": "309783001",
            "description": "Esophageal varices in alcoholic cirrhosis of the liver",
            "attributes": null
          },
          {
            "code": "31155007",
            "description": "Benign recurrent intrahepatic cholestasis",
            "attributes": null
          },
          {
            "code": "314963000",
            "description": "Local recurrence of malignant neoplasm of liver",
            "attributes": null
          },
          {
            "code": "31712002",
            "description": "Primary biliary cholangitis",
            "attributes": null
          },
          {
            "code": "328383001",
            "description": "Chronic liver disease",
            "attributes": null
          },
          {
            "code": "33144001",
            "description": "Parasitic cirrhosis",
            "attributes": null
          },
          {
            "code": "33167004",
            "description": "Complication of transplanted liver",
            "attributes": null
          },
          {
            "code": "34736002",
            "description": "Chronic passive congestion of liver",
            "attributes": null
          },
          {
            "code": "347891000119103",
            "description": "Chronic hepatitis C with stage 3 fibrosis",
            "attributes": null
          },
          {
            "code": "371139006",
            "description": "Early cirrhosis",
            "attributes": null
          },
          {
            "code": "37688005",
            "description": "Clonorchiasis with biliary cirrhosis",
            "attributes": null
          },
          {
            "code": "38662009",
            "description": "Chronic persistent type B viral hepatitis",
            "attributes": null
          },
          {
            "code": "408335007",
            "description": "Autoimmune hepatitis",
            "attributes": null
          },
          {
            "code": "41889008",
            "description": "Chronic persistent hepatitis",
            "attributes": null
          },
          {
            "code": "419728003",
            "description": "Portal cirrhosis",
            "attributes": null
          },
          {
            "code": "420054005",
            "description": "Alcoholic cirrhosis",
            "attributes": null
          },
          {
            "code": "425413006",
            "description": "Drug-induced cirrhosis of liver",
            "attributes": null
          },
          {
            "code": "426356008",
            "description": "Orthotopic transplantation of whole liver",
            "attributes": null
          },
          {
            "code": "431222008",
            "description": "Acute rejection of liver transplant",
            "attributes": null
          },
          {
            "code": "432772009",
            "description": "Hyperacute rejection of liver transplant",
            "attributes": null
          },
          {
            "code": "432777003",
            "description": "Accelerated rejection of liver transplant",
            "attributes": null
          },
          {
            "code": "432908002",
            "description": "Chronic rejection of liver transplant",
            "attributes": null
          },
          {
            "code": "43904005",
            "description": "Macronodular cirrhosis",
            "attributes": null
          },
          {
            "code": "450880008",
            "description": "Chronic hepatitis E",
            "attributes": null
          },
          {
            "code": "45256007",
            "description": "Cruveilhier-Baumgarten syndrome",
            "attributes": null
          },
          {
            "code": "470971000000107",
            "description": "[X]Other and unspecified cirrhosis of liver",
            "attributes": null
          },
          {
            "code": "50167007",
            "description": "Chronic active type B viral hepatitis",
            "attributes": null
          },
          {
            "code": "536002",
            "description": "Glissonian cirrhosis",
            "attributes": null
          },
          {
            "code": "57339008",
            "description": "Chronic lobular hepatitis",
            "attributes": null
          },
          {
            "code": "589541000000101",
            "description": "Infectious cirrhosis NOS",
            "attributes": null
          },
          {
            "code": "589551000000103",
            "description": "Portal cirrhosis unspecified",
            "attributes": null
          },
          {
            "code": "589561000000100",
            "description": "Biliary cirrhosis NOS",
            "attributes": null
          },
          {
            "code": "60037002",
            "description": "Chronic persistent viral hepatitis",
            "attributes": null
          },
          {
            "code": "6183001",
            "description": "Indian childhood cirrhosis",
            "attributes": null
          },
          {
            "code": "61977001",
            "description": "Chronic type B viral hepatitis",
            "attributes": null
          },
          {
            "code": "662341000000105",
            "description": "Cirrhosis of liver NOS",
            "attributes": null
          },
          {
            "code": "66870002",
            "description": "Chronic active viral hepatitis",
            "attributes": null
          },
          {
            "code": "671731000000104",
            "description": "Non-alcoholic cirrhosis NOS",
            "attributes": null
          },
          {
            "code": "699189004",
            "description": "North American Indian childhood cirrhosis",
            "attributes": null
          },
          {
            "code": "702377007",
            "description": "Hypermanganesemia with dystonia, polycythemia, and cirrhosis",
            "attributes": null
          },
          {
            "code": "702969000",
            "description": "Reactivation of hepatitis C viral hepatitis",
            "attributes": null
          },
          {
            "code": "703866000",
            "description": "Chronic hepatitis C with stage 2 fibrosis",
            "attributes": null
          },
          {
            "code": "708198006",
            "description": "Chronic active hepatitis C",
            "attributes": null
          },
          {
            "code": "708248004",
            "description": "End stage liver disease",
            "attributes": null
          },
          {
            "code": "710066005",
            "description": "Child-Pugh score class B",
            "attributes": null
          },
          {
            "code": "710067001",
            "description": "Child-Pugh score class C",
            "attributes": null
          },
          {
            "code": "713181003",
            "description": "Chronic alcoholic liver disease",
            "attributes": null
          },
          {
            "code": "713966008",
            "description": "Occult chronic type B viral hepatitis",
            "attributes": null
          },
          {
            "code": "715401008",
            "description": "Primary biliary cirrhosis co-occurrent with systemic scleroderma",
            "attributes": null
          },
          {
            "code": "715864007",
            "description": "Non-Wilsonian hepatic copper toxicosis of infancy and childhood",
            "attributes": null
          },
          {
            "code": "716203000",
            "description": "Decompensated cirrhosis of liver",
            "attributes": null
          },
          {
            "code": "717156002",
            "description": "Biliary atresia with splenic malformation syndrome",
            "attributes": null
          },
          {
            "code": "721711009",
            "description": "Autoimmune hepatitis type 1",
            "attributes": null
          },
          {
            "code": "721712002",
            "description": "Autoimmune hepatitis type 2",
            "attributes": null
          },
          {
            "code": "721713007",
            "description": "Autoimmune hepatitis type 3",
            "attributes": null
          },
          {
            "code": "725416005",
            "description": "Cardiomyopathy due to cirrhosis of liver",
            "attributes": null
          },
          {
            "code": "725938001",
            "description": "Cirrhosis of liver caused by methotrexate",
            "attributes": null
          },
          {
            "code": "725939009",
            "description": "Cirrhosis of liver caused by amiodarone",
            "attributes": null
          },
          {
            "code": "725940006",
            "description": "Cirrhosis of liver caused by methyldopa",
            "attributes": null
          },
          {
            "code": "73475009",
            "description": "Hepatogenous chronic copper poisoning",
            "attributes": null
          },
          {
            "code": "735451005",
            "description": "Chronic infection caused by Hepatitis D virus",
            "attributes": null
          },
          {
            "code": "735732003",
            "description": "Liver disease co-occurrent and due to mitochondrial disorder",
            "attributes": null
          },
          {
            "code": "735733008",
            "description": "Cirrhosis of liver co-occurrent and due to primary sclerosing cholangitis",
            "attributes": null
          },
          {
            "code": "737297006",
            "description": "Transplanted liver present",
            "attributes": null
          },
          {
            "code": "74162007",
            "description": "Progressive intrahepatic cholestasis",
            "attributes": null
          },
          {
            "code": "74669004",
            "description": "Cardiac cirrhosis",
            "attributes": null
          },
          {
            "code": "76301009",
            "description": "Florid cirrhosis",
            "attributes": null
          },
          {
            "code": "765482002",
            "description": "Steatohepatitis caused by ingestible alcohol",
            "attributes": null
          },
          {
            "code": "767809001",
            "description": "Chronic hepatitis C caused by hepatitis C virus genotype 6",
            "attributes": null
          },
          {
            "code": "767810006",
            "description": "Chronic hepatitis C caused by hepatitis C virus genotype 5",
            "attributes": null
          },
          {
            "code": "76783007",
            "description": "Chronic hepatitis",
            "attributes": null
          },
          {
            "code": "768006009",
            "description": "Chronic hepatitis C caused by Hepatitis C virus genotype 3",
            "attributes": null
          },
          {
            "code": "768125005",
            "description": "Chronic hepatitis C caused by Hepatitis C virus genotype 2",
            "attributes": null
          },
          {
            "code": "768126006",
            "description": "Chronic hepatitis C caused by Hepatitis C virus genotype 4",
            "attributes": null
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