[
  {
    "phenotype_id": "PH2372",
    "phenotype_version_id": 5632,
    "name": "Complement disorder codes",
    "definition": "This codelist was taken from [OpenCodelists](https://www.opencodelists.org/), created by [OpenSAFELY](https://www.opensafely.org/). We recommend viewing this Phenotype on the OpenCodelist website to view the most recent version.\n\n\nTaken from the `COMPLEMENTDIS_COD` refset published by NHSD. Contains public sector information licensed under the UK Open Government Licence v3\\.0 (https://www.nationalarchives.gov.uk/doc/open\\-government\\-licence/version/3/).\n\n\n© University of Oxford for the Bennett Institute for Applied Data Science 2025\\. This work may be copied freely for non\\-commercial research and study.\n\n",
    "implementation": null,
    "publications": null,
    "validation": null,
    "citation_requirements": null,
    "created": "2026-01-26T22:10:33.375620Z",
    "author": "NHSD Primary Care Domain Refsets",
    "collections": [
      {
        "name": "OpenCodelist",
        "value": 31
      },
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": {
      "id": 1,
      "slug": "opensafely",
      "name": "OpenSAFELY"
    },
    "world_access": 1,
    "updated": "2026-01-26T22:10:36.954380Z",
    "references": [
      {
        "url": "https://digital.nhs.uk/data-and-information/data-collections-and-data-sets/data-collections/quality-and-outcomes-framework-qof/quality-and-outcome-framework-qof-business-rules/primary-care-domain-reference-set-portal",
        "title": "Primary Care Domain Reference Set Portal"
      }
    ],
    "signed_off": [],
    "methodology": "",
    "coding_system": [
      {
        "name": "SNOMED  CT codes",
        "value": 9
      }
    ],
    "open_codelist_id": "nhsd-primary-care-domain-refsets/complementdis_cod",
    "source_reference": "https://www.opencodelists.org/codelist/nhsd-primary-care-domain-refsets/complementdis_cod/20250912",
    "concept_information": [
      {
        "concept_id": 5809,
        "concept_version_id": 13294,
        "concept_name": "nhsd-primary-care-domain-refsets/complementdis_cod/20250912",
        "coding_system": {
          "id": 9,
          "name": "SNOMED  CT codes",
          "description": "SNOMED CT codes"
        },
        "phenotype_id": "PH2372",
        "phenotype_version_id": 5632,
        "phenotype_name": "Complement disorder codes",
        "code_attribute_header": [],
        "codes": [
          {
            "code": "1162263002",
            "description": "Complement component 8 deficiency",
            "attributes": null
          },
          {
            "code": "1279887007",
            "description": "Complement hyperactivation, angiopathic thrombosis, protein losing enteropathy syndrome",
            "attributes": null
          },
          {
            "code": "1293264009",
            "description": "Atypical hemolytic uremic syndrome with complement gene abnormality",
            "attributes": null
          },
          {
            "code": "1295220004",
            "description": "Atypical hemolytic uremic syndrome with anti-factor H antibodies",
            "attributes": null
          },
          {
            "code": "18827005",
            "description": "Complement abnormality",
            "attributes": null
          },
          {
            "code": "234593008",
            "description": "Classical complement pathway abnormality",
            "attributes": null
          },
          {
            "code": "234594002",
            "description": "Complement 1q deficiency",
            "attributes": null
          },
          {
            "code": "234595001",
            "description": "Complement 1q beta chain deficiency",
            "attributes": null
          },
          {
            "code": "234596000",
            "description": "Complement 1q dysfunction",
            "attributes": null
          },
          {
            "code": "234597009",
            "description": "Complement 1r deficiency",
            "attributes": null
          },
          {
            "code": "234598004",
            "description": "Complement 1s deficiency",
            "attributes": null
          },
          {
            "code": "234599007",
            "description": "Complement 2 deficiency",
            "attributes": null
          },
          {
            "code": "234600005",
            "description": "Complement 4 deficiency",
            "attributes": null
          },
          {
            "code": "234601009",
            "description": "Complement 4A deficiency",
            "attributes": null
          },
          {
            "code": "234602002",
            "description": "Complement 4B deficiency",
            "attributes": null
          },
          {
            "code": "234603007",
            "description": "Complement 3 deficiency",
            "attributes": null
          },
          {
            "code": "234609006",
            "description": "Complement 5 deficiency",
            "attributes": null
          },
          {
            "code": "234611002",
            "description": "Complement 6 deficiency",
            "attributes": null
          },
          {
            "code": "234612009",
            "description": "Complement 7 deficiency",
            "attributes": null
          },
          {
            "code": "234613004",
            "description": "Combined complement 6 and 7 deficiencies",
            "attributes": null
          },
          {
            "code": "234614005",
            "description": "Complement 8 beta chain deficiency",
            "attributes": null
          },
          {
            "code": "234615006",
            "description": "Complement 8 beta chain dysfunction",
            "attributes": null
          },
          {
            "code": "234616007",
            "description": "Complement 8 alpha-gamma deficiency",
            "attributes": null
          },
          {
            "code": "234617003",
            "description": "Complement 9 deficiency",
            "attributes": null
          },
          {
            "code": "234618008",
            "description": "Complement regulatory factor defect",
            "attributes": null
          },
          {
            "code": "234623008",
            "description": "Complement 4 binding protein deficiency",
            "attributes": null
          },
          {
            "code": "234626000",
            "description": "Complement 5a inhibitor deficiency",
            "attributes": null
          },
          {
            "code": "234628004",
            "description": "Complement receptor deficiency",
            "attributes": null
          },
          {
            "code": "234629007",
            "description": "Complement receptor 1 deficiency",
            "attributes": null
          },
          {
            "code": "234630002",
            "description": "Complement receptor 3 deficiency",
            "attributes": null
          },
          {
            "code": "24419001",
            "description": "Disorder of complement",
            "attributes": null
          },
          {
            "code": "24743004",
            "description": "Complement deficiency disease",
            "attributes": null
          },
          {
            "code": "263661007",
            "description": "Complement 5 dysfunction",
            "attributes": null
          },
          {
            "code": "363009005",
            "description": "Complement component deficiency",
            "attributes": null
          },
          {
            "code": "771443008",
            "description": "Complement component 3 deficiency",
            "attributes": null
          }
        ]
      }
    ],
    "coding_system_release": "",
    "open_codelist_version_id": "2d796a13",
    "open_codelist_version_tag": "20250912",
    "status": 1,
    "doi": "https://doi.org/10.48533/d6z6-j691",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 3,
      "name": "OpenCodelists Phenotype",
      "description": "OpenSafely's OpenCodelist Phenotype, visit https://www.opencodelists.org/ to learn more",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 5632,
        "version_name": "Complement disorder codes",
        "version_date": "2026-01-26T22:10:36.964610Z",
        "is_published": true,
        "is_latest": true
      },
      {
        "version_id": 5631,
        "version_name": "Complement disorder codes",
        "version_date": "2026-01-26T22:10:35.741882Z",
        "is_published": true,
        "is_latest": false
      },
      {
        "version_id": 5630,
        "version_name": "Complement disorder codes",
        "version_date": "2026-01-26T22:10:34.590084Z",
        "is_published": true,
        "is_latest": false
      },
      {
        "version_id": 5629,
        "version_name": "Complement disorder codes",
        "version_date": "2026-01-26T22:10:33.388173Z",
        "is_published": true,
        "is_latest": false
      }
    ]
  }
]