[
  {
    "phenotype_id": "PH2500",
    "phenotype_version_id": 6067,
    "name": "Down’s syndrome codes",
    "definition": "This codelist was taken from [OpenCodelists](https://www.opencodelists.org/), created by [OpenSAFELY](https://www.opensafely.org/). We recommend viewing this Phenotype on the OpenCodelist website to view the most recent version.\n\n\nTaken from the `DS_COD` refset published by NHSD. Contains public sector information licensed under the UK Open Government Licence v3\\.0 (https://www.nationalarchives.gov.uk/doc/open\\-government\\-licence/version/3/).\n\n\n© University of Oxford for the Bennett Institute for Applied Data Science 2025\\. This work may be copied freely for non\\-commercial research and study.\n\n",
    "implementation": null,
    "publications": null,
    "validation": null,
    "citation_requirements": null,
    "created": "2026-01-26T22:19:35.942990Z",
    "author": "NHSD Primary Care Domain Refsets",
    "collections": [
      {
        "name": "OpenCodelist",
        "value": 31
      },
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": {
      "id": 1,
      "slug": "opensafely",
      "name": "OpenSAFELY"
    },
    "world_access": 1,
    "updated": "2026-01-26T22:19:39.268771Z",
    "references": [
      {
        "url": "https://digital.nhs.uk/data-and-information/data-collections-and-data-sets/data-collections/quality-and-outcomes-framework-qof/quality-and-outcome-framework-qof-business-rules/primary-care-domain-reference-set-portal",
        "title": "Primary Care Domain Reference Set Portal"
      }
    ],
    "signed_off": [],
    "methodology": "",
    "coding_system": [
      {
        "name": "SNOMED  CT codes",
        "value": 9
      }
    ],
    "open_codelist_id": "nhsd-primary-care-domain-refsets/ds_cod",
    "source_reference": "https://www.opencodelists.org/codelist/nhsd-primary-care-domain-refsets/ds_cod/20250912",
    "concept_information": [
      {
        "concept_id": 6244,
        "concept_version_id": 13729,
        "concept_name": "nhsd-primary-care-domain-refsets/ds_cod/20250912",
        "coding_system": {
          "id": 9,
          "name": "SNOMED  CT codes",
          "description": "SNOMED CT codes"
        },
        "phenotype_id": "PH2500",
        "phenotype_version_id": 6067,
        "phenotype_name": "Down’s syndrome codes",
        "code_attribute_header": [],
        "codes": [
          {
            "code": "1184621000",
            "description": "Periodontitis exacerbated by Down syndrome",
            "attributes": null
          },
          {
            "code": "157019002",
            "description": "Down's syndrome",
            "attributes": null
          },
          {
            "code": "205614001",
            "description": "(Down's syndrome - trisomy 21) or (mongolism) or (trisomy 21) or (trisomy 22)",
            "attributes": null
          },
          {
            "code": "205615000",
            "description": "Trisomy 21- meiotic nondisjunction",
            "attributes": null
          },
          {
            "code": "205616004",
            "description": "Trisomy 21- mitotic nondisjunction mosaicism",
            "attributes": null
          },
          {
            "code": "205617008",
            "description": "Partial trisomy 21 in Down's syndrome",
            "attributes": null
          },
          {
            "code": "205618003",
            "description": "Down's syndrome NOS",
            "attributes": null
          },
          {
            "code": "254263008",
            "description": "Down's syndrome NOS",
            "attributes": null
          },
          {
            "code": "254264002",
            "description": "Partial trisomy 21 in Down's syndrome",
            "attributes": null
          },
          {
            "code": "371045000",
            "description": "Translocation Down syndrome",
            "attributes": null
          },
          {
            "code": "41040004",
            "description": "Complete trisomy 21 syndrome",
            "attributes": null
          },
          {
            "code": "450935006",
            "description": "Myeloid leukemia associated with Down Syndrome",
            "attributes": null
          },
          {
            "code": "702711000000103",
            "description": "Down's syndrome NOS",
            "attributes": null
          },
          {
            "code": "709469005",
            "description": "Periodontitis co-occurrent with Down syndrome",
            "attributes": null
          },
          {
            "code": "724643004",
            "description": "Transient abnormal myelopoiesis co-occurrent with Down syndrome",
            "attributes": null
          },
          {
            "code": "724644005",
            "description": "Myeloid leukemia associated with Down syndrome",
            "attributes": null
          },
          {
            "code": "733194007",
            "description": "Dementia co-occurrent and due to Down syndrome",
            "attributes": null
          },
          {
            "code": "840505007",
            "description": "Down syndrome co-occurrent with leukemoid reaction associated transient neonatal pustulosis",
            "attributes": null
          }
        ]
      }
    ],
    "coding_system_release": "",
    "open_codelist_version_id": "5ce59087",
    "open_codelist_version_tag": "20250912",
    "status": 1,
    "doi": "https://doi.org/10.48533/7q8p-mx19",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 3,
      "name": "OpenCodelists Phenotype",
      "description": "OpenSafely's OpenCodelist Phenotype, visit https://www.opencodelists.org/ to learn more",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 6067,
        "version_name": "Downs syndrome codes",
        "version_date": "2026-01-26T22:19:39.283169Z",
        "is_published": true,
        "is_latest": true
      },
      {
        "version_id": 6066,
        "version_name": "Downs syndrome codes",
        "version_date": "2026-01-26T22:19:38.153683Z",
        "is_published": true,
        "is_latest": false
      },
      {
        "version_id": 6065,
        "version_name": "Downs syndrome codes",
        "version_date": "2026-01-26T22:19:37.054074Z",
        "is_published": true,
        "is_latest": false
      },
      {
        "version_id": 6064,
        "version_name": "Downs syndrome codes",
        "version_date": "2026-01-26T22:19:35.952739Z",
        "is_published": true,
        "is_latest": false
      }
    ]
  }
]