[
  {
    "phenotype_id": "PH3113",
    "phenotype_version_id": 8086,
    "name": "Beta-blocker contraindications (persisting)",
    "definition": "This codelist was taken from [OpenCodelists](https://www.opencodelists.org/), created by [OpenSAFELY](https://www.opensafely.org/). We recommend viewing this Phenotype on the OpenCodelist website to view the most recent version.\n\n\nTaken from the `XLBB_COD` refset published by NHSD. Contains public sector information licensed under the UK Open Government Licence v3\\.0 (https://www.nationalarchives.gov.uk/doc/open\\-government\\-licence/version/3/).\n\n\n© University of Oxford for the Bennett Institute for Applied Data Science 2025\\. This work may be copied freely for non\\-commercial research and study.\n\n",
    "implementation": null,
    "publications": null,
    "validation": null,
    "citation_requirements": null,
    "created": "2026-01-26T23:04:05.877612Z",
    "author": "NHSD Primary Care Domain Refsets",
    "collections": [
      {
        "name": "OpenCodelist",
        "value": 31
      },
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": {
      "id": 1,
      "slug": "opensafely",
      "name": "OpenSAFELY"
    },
    "world_access": 1,
    "updated": "2026-01-26T23:04:09.502095Z",
    "references": [
      {
        "url": "https://digital.nhs.uk/data-and-information/data-collections-and-data-sets/data-collections/quality-and-outcomes-framework-qof/quality-and-outcome-framework-qof-business-rules/primary-care-domain-reference-set-portal",
        "title": "Primary Care Domain Reference Set Portal"
      }
    ],
    "signed_off": [],
    "methodology": "",
    "coding_system": [
      {
        "name": "SNOMED  CT codes",
        "value": 9
      }
    ],
    "open_codelist_id": "nhsd-primary-care-domain-refsets/xlbb_cod",
    "source_reference": "https://www.opencodelists.org/codelist/nhsd-primary-care-domain-refsets/xlbb_cod/20250912",
    "concept_information": [
      {
        "concept_id": 8263,
        "concept_version_id": 15748,
        "concept_name": "nhsd-primary-care-domain-refsets/xlbb_cod/20250912",
        "coding_system": {
          "id": 9,
          "name": "SNOMED  CT codes",
          "description": "SNOMED CT codes"
        },
        "phenotype_id": "PH3113",
        "phenotype_version_id": 8086,
        "phenotype_name": "Beta-blocker contraindications (persisting)",
        "code_attribute_header": [],
        "codes": [
          {
            "code": "1053591000000102",
            "description": "Nebivolol allergy",
            "attributes": null
          },
          {
            "code": "1053601000000108",
            "description": "Nebivolol adverse reaction",
            "attributes": null
          },
          {
            "code": "1269396003",
            "description": "Hypersensitivity to atenolol",
            "attributes": null
          },
          {
            "code": "292419005",
            "description": "Beta-adrenoceptor blocking drug adverse reaction",
            "attributes": null
          },
          {
            "code": "292420004",
            "description": "Cardioselective beta-blocker adverse reaction",
            "attributes": null
          },
          {
            "code": "292421000",
            "description": "Acebutolol adverse reaction",
            "attributes": null
          },
          {
            "code": "292424008",
            "description": "Betaxolol adverse reaction",
            "attributes": null
          },
          {
            "code": "292425009",
            "description": "Bisoprolol adverse reaction",
            "attributes": null
          },
          {
            "code": "292426005",
            "description": "Celiprolol adverse reaction",
            "attributes": null
          },
          {
            "code": "292427001",
            "description": "Esmolol adverse reaction",
            "attributes": null
          },
          {
            "code": "292428006",
            "description": "Metoprolol adverse reaction",
            "attributes": null
          },
          {
            "code": "292429003",
            "description": "Non-cardioselective beta-blocker adverse reaction",
            "attributes": null
          },
          {
            "code": "292430008",
            "description": "Nadolol adverse reaction",
            "attributes": null
          },
          {
            "code": "292431007",
            "description": "Pindolol adverse reaction",
            "attributes": null
          },
          {
            "code": "292432000",
            "description": "Carvedilol adverse reaction",
            "attributes": null
          },
          {
            "code": "292433005",
            "description": "Metipranolol adverse reaction",
            "attributes": null
          },
          {
            "code": "292434004",
            "description": "Carteolol adverse reaction",
            "attributes": null
          },
          {
            "code": "292435003",
            "description": "Labetalol adverse reaction",
            "attributes": null
          },
          {
            "code": "292436002",
            "description": "Levobunolol adverse reaction",
            "attributes": null
          },
          {
            "code": "292437006",
            "description": "Oxprenolol adverse reaction",
            "attributes": null
          },
          {
            "code": "292438001",
            "description": "Penbutolol adverse reaction",
            "attributes": null
          },
          {
            "code": "292439009",
            "description": "Practolol adverse reaction",
            "attributes": null
          },
          {
            "code": "292440006",
            "description": "Propranolol adverse reaction",
            "attributes": null
          },
          {
            "code": "292441005",
            "description": "Sotalol adverse reaction",
            "attributes": null
          },
          {
            "code": "292442003",
            "description": "Timolol adverse reaction",
            "attributes": null
          },
          {
            "code": "293962009",
            "description": "Allergy to beta adrenergic receptor antagonist",
            "attributes": null
          },
          {
            "code": "293963004",
            "description": "Allergy to beta-1 adrenergic receptor antagonist",
            "attributes": null
          },
          {
            "code": "293964005",
            "description": "Allergy to acebutolol",
            "attributes": null
          },
          {
            "code": "293965006",
            "description": "Allergy to atenolol",
            "attributes": null
          },
          {
            "code": "293966007",
            "description": "Allergy to betaxolol",
            "attributes": null
          },
          {
            "code": "293967003",
            "description": "Allergy to bisoprolol",
            "attributes": null
          },
          {
            "code": "293968008",
            "description": "Allergy to celiprolol",
            "attributes": null
          },
          {
            "code": "293969000",
            "description": "Allergy to esmolol",
            "attributes": null
          },
          {
            "code": "293970004",
            "description": "Allergy to metoprolol",
            "attributes": null
          },
          {
            "code": "293971000",
            "description": "Non-cardioselective beta-blocker allergy",
            "attributes": null
          },
          {
            "code": "293972007",
            "description": "Allergy to nadolol",
            "attributes": null
          },
          {
            "code": "293973002",
            "description": "Allergy to pindolol",
            "attributes": null
          },
          {
            "code": "293974008",
            "description": "Allergy to carvedilol",
            "attributes": null
          },
          {
            "code": "293975009",
            "description": "Allergy to metipranolol",
            "attributes": null
          },
          {
            "code": "293976005",
            "description": "Allergy to carteolol",
            "attributes": null
          },
          {
            "code": "293977001",
            "description": "Allergy to labetalol",
            "attributes": null
          },
          {
            "code": "293978006",
            "description": "Allergy to levobunolol",
            "attributes": null
          },
          {
            "code": "293979003",
            "description": "Allergy to oxprenolol",
            "attributes": null
          },
          {
            "code": "293980000",
            "description": "Allergy to penbutolol",
            "attributes": null
          },
          {
            "code": "293981001",
            "description": "Allergy to practolol",
            "attributes": null
          },
          {
            "code": "293982008",
            "description": "Allergy to propranolol",
            "attributes": null
          },
          {
            "code": "293983003",
            "description": "Allergy to sotalol",
            "attributes": null
          },
          {
            "code": "293984009",
            "description": "Allergy to timolol",
            "attributes": null
          },
          {
            "code": "418370000",
            "description": "Atenolol adverse reaction",
            "attributes": null
          },
          {
            "code": "419869001",
            "description": "Atenolol sensitivity",
            "attributes": null
          },
          {
            "code": "720665007",
            "description": "Adverse reaction caused by metoprolol succinate",
            "attributes": null
          },
          {
            "code": "720666008",
            "description": "Adverse reaction caused by metoprolol tartrate",
            "attributes": null
          },
          {
            "code": "772020009",
            "description": "Adverse reaction caused by nebivolol",
            "attributes": null
          },
          {
            "code": "772021008",
            "description": "Allergy to nebivolol",
            "attributes": null
          }
        ]
      }
    ],
    "coding_system_release": "",
    "open_codelist_version_id": "77ea7920",
    "open_codelist_version_tag": "20250912",
    "status": 1,
    "doi": "https://doi.org/10.48533/8v9z-gf42",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 3,
      "name": "OpenCodelists Phenotype",
      "description": "OpenSafely's OpenCodelist Phenotype, visit https://www.opencodelists.org/ to learn more",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 8086,
        "version_name": "Beta-blocker contraindications (persisting)",
        "version_date": "2026-01-26T23:04:09.510222Z",
        "is_published": true,
        "is_latest": true
      },
      {
        "version_id": 8085,
        "version_name": "Beta-blocker contraindications (persisting)",
        "version_date": "2026-01-26T23:04:08.251168Z",
        "is_published": true,
        "is_latest": false
      },
      {
        "version_id": 8084,
        "version_name": "Beta-blocker contraindications (persisting)",
        "version_date": "2026-01-26T23:04:07.084363Z",
        "is_published": true,
        "is_latest": false
      },
      {
        "version_id": 8083,
        "version_name": "Beta-blocker contraindications (persisting)",
        "version_date": "2026-01-26T23:04:05.886129Z",
        "is_published": true,
        "is_latest": false
      }
    ]
  }
]