[ { "phenotype_id": "PH312", "phenotype_version_id": 624, "name": "Splenomegaly", "definition": "At the specified date, a patient is defined as having had Splenomegaly IF they meet the criteria for any of the following on or before the specified date. The earliest date on which the individual meets any of the following criteria on or before the specified date is defined as the first event date:\n\n\nPrimary care\n\n\n1. Splenomegaly diagnosis or history of diagnosis during a consultation \n\nOR\nSecondary care (ICD10)\n\n\n1. ALL diagnoses of Splenomegaly or history of diagnosis during a hospitalization\n\n\n\n\n\n\n\n\n\n\n\n\n", "implementation": "", "publications": [ { "doi": "10.1016/S2589-7500(19)30012-3", "details": "Kuan V., Denaxas S., Gonzalez-Izquierdo A. et al. A chronological map of 308 physical and mental health conditions from 4 million individuals in the National Health Service. The Lancet Digital Health - DOI 10.1016/S2589-7500(19)30012-3" } ], "validation": "", "citation_requirements": "", "created": "2021-10-06T16:12:14.188601Z", "author": "Kuan V, Denaxas S, Gonzalez-Izquierdo A, Direk K, Bhatti O, Husain S, Sutaria S, Hingorani M, Nitsch D, Parisinos C, Lumbers T, Mathur R, Sofat R, Casas JP, Wong I, Hemingway H, Hingorani A", "collections": [ { "name": "CALIBER", "value": 21 }, { "name": "Phenotype Library", "value": 18 } ], "tags": null, "organisation": null, "world_access": 1, "updated": "2021-10-06T16:12:14.188630Z", "sex": [ { "name": "Both", "value": "3" } ], "type": [ { "name": "Disease or syndrome", "value": "2" } ], "ontology": null, "phenoflowid": "https://kclhi.org/phenoflow/workflows/github.com/phenoflow/Splenomegaly---7dd25cc0-17c1-11ef-9de4-4d4ea830ad16/blob/read-potential-cases-fhir/Splenomegaly.cwl", "data_sources": [ { "name": "CPRD GOLD", "value": 5, "uid": "a29feafa-7bdd-44e9-b977-c9d26425e67f", "url": "https://healthdatagateway.org/en/dataset/694", "datasource_id": 694 }, { "name": "HES Admitted Patient Care data for CPRD GOLD", "value": 9, "uid": "4bcf64a6-f404-4ef4-ae6e-172512ab5f43", "url": "https://healthdatagateway.org/en/dataset/674", "datasource_id": 674 } ], "coding_system": [ { "name": "ICD10 codes", "value": 4 }, { "name": "Read codes v2", "value": 5 }, { "name": "Med codes", "value": 8 } ], "event_date_range": "01/01/1999 - 01/07/2016", "concept_information": [ { "concept_id": 1579, "concept_version_id": 4297, "concept_name": "Splenomegaly - Primary care", "coding_system": { "id": 5, "name": "Read codes v2", "description": "Read codes v2" }, "phenotype_id": "PH312", "phenotype_version_id": 624, "phenotype_name": "Splenomegaly", "code_attribute_header": [ "Disease", "Medcode", "Category" ], "codes": [ { "code": "D414.00", "description": "Hypersplenism", "attributes": { "Disease": "Splenomegaly", "Medcode": "10702.0", "Category": "Diagnosis of Splenomegaly" } }, { "code": "D415100", "description": "Chronic congestive splenamegaly", "attributes": { "Disease": "Splenomegaly", "Medcode": "96439.0", "Category": "Diagnosis of Splenomegaly" } }, { "code": "J61y200", "description": "Hepatosplenomegaly", "attributes": { "Disease": "Splenomegaly", "Medcode": "1780.0", "Category": "Diagnosis of Splenomegaly" } }, { "code": "PK03.00", "description": "Congenital splenomegaly", "attributes": { "Disease": "Splenomegaly", "Medcode": "59741.0", "Category": "Diagnosis of Splenomegaly" } }, { "code": "PK03.11", "description": "Hyperplasia of spleen", "attributes": { "Disease": "Splenomegaly", "Medcode": "62455.0", "Category": "Diagnosis of Splenomegaly" } }, { "code": "R092.00", "description": "[D]Splenomegaly", "attributes": { "Disease": "Splenomegaly", "Medcode": "3125.0", "Category": "Diagnosis of Splenomegaly" } }, { "code": "R092000", "description": "[D]Spleen enlargement", "attributes": { "Disease": "Splenomegaly", "Medcode": "29832.0", "Category": "Diagnosis of Splenomegaly" } }, { "code": "R092z00", "description": "[D]Splenomegaly NOS", "attributes": { "Disease": "Splenomegaly", "Medcode": "44281.0", "Category": "Diagnosis of Splenomegaly" } } ] }, { "concept_id": 1580, "concept_version_id": 4299, "concept_name": "Splenomegaly - Primary care", "coding_system": { "id": 8, "name": "Med codes", "description": "Med codes" }, "phenotype_id": "PH312", "phenotype_version_id": 624, "phenotype_name": "Splenomegaly", "code_attribute_header": [ "Disease", "ReadcodeDescr", "Readcode" ], "codes": [ { "code": "10702.0", "description": "Diagnosis of Splenomegaly", "attributes": { "Disease": "Splenomegaly", "ReadcodeDescr": "Hypersplenism", "Readcode": "D414.00" } }, { "code": "1780.0", "description": "Diagnosis of Splenomegaly", "attributes": { "Disease": "Splenomegaly", "ReadcodeDescr": "Hepatosplenomegaly", "Readcode": "J61y200" } }, { "code": "29832.0", "description": "Diagnosis of Splenomegaly", "attributes": { "Disease": "Splenomegaly", "ReadcodeDescr": "[D]Spleen enlargement", "Readcode": "R092000" } }, { "code": "3125.0", "description": "Diagnosis of Splenomegaly", "attributes": { "Disease": "Splenomegaly", "ReadcodeDescr": "[D]Splenomegaly", "Readcode": "R092.00" } }, { "code": "44281.0", "description": "Diagnosis of Splenomegaly", "attributes": { "Disease": "Splenomegaly", "ReadcodeDescr": "[D]Splenomegaly NOS", "Readcode": "R092z00" } }, { "code": "59741.0", "description": "Diagnosis of Splenomegaly", "attributes": { "Disease": "Splenomegaly", "ReadcodeDescr": "Congenital splenomegaly", "Readcode": "PK03.00" } }, { "code": "62455.0", "description": "Diagnosis of Splenomegaly", "attributes": { "Disease": "Splenomegaly", "ReadcodeDescr": "Hyperplasia of spleen", "Readcode": "PK03.11" } }, { "code": "96439.0", "description": "Diagnosis of Splenomegaly", "attributes": { "Disease": "Splenomegaly", "ReadcodeDescr": "Chronic congestive splenamegaly", "Readcode": "D415100" } } ] }, { "concept_id": 1581, "concept_version_id": 4301, "concept_name": "Splenomegaly - Secondary care - Diagnoses", "coding_system": { "id": 4, "name": "ICD10 codes", "description": "ICD10 Codes" }, "phenotype_id": "PH312", "phenotype_version_id": 624, "phenotype_name": "Splenomegaly", "code_attribute_header": [ "Disease", "Category" ], "codes": [ { "code": "D73.1", "description": "Hypersplenism", "attributes": { "Disease": "Splenomegaly", "Category": "Diagnosis of Splenomegaly" } }, { "code": "D73.2", "description": "Chronic congestive splenomegaly", "attributes": { "Disease": "Splenomegaly", "Category": "Diagnosis of Splenomegaly" } }, { "code": "R16.1", "description": "Splenomegaly, not elsewhere classified", "attributes": { "Disease": "Splenomegaly", "Category": "Diagnosis of Splenomegaly" } }, { "code": "R16.2", "description": "Hepatomegaly with splenomegaly, not elsewhere classified", "attributes": { "Disease": "Splenomegaly", "Category": "Diagnosis of Splenomegaly" } } ] } ], "status": 2, "doi": "https://doi.org/10.48533/93zf-w243", "is_deleted": null, "publish_status": 2, "owner": "ieuan.scanlon", "template": { "id": 1, "name": "Clinical-Coded Phenotype", "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.", "version_id": 1 }, "versions": [ { "version_id": 624, "version_name": "Splenomegaly", "version_date": "2021-10-06T16:12:14.221030Z", "is_published": true, "is_latest": true } ] } ]