[ { "phenotype_id": "PH3283", "phenotype_version_id": 8276, "name": "Aplastic Anaemia", "definition": "This codelist was taken from [OpenCodelists](https://www.opencodelists.org/), created by [OpenSAFELY](https://www.opensafely.org/). We recommend viewing this Phenotype on the OpenCodelist website to view the most recent version.\n\n\nCodes indicating diagnosis of aplastic anaemia\n\n\n© University of Oxford for the Bennett Institute for Applied Data Science 2025\\. This work may be copied freely for non\\-commercial research and study.\n\n", "implementation": null, "publications": null, "validation": null, "citation_requirements": null, "created": "2026-01-26T23:09:26.280375Z", "author": "OpenSAFELY", "collections": [ { "name": "OpenCodelist", "value": 31 }, { "name": "Phenotype Library", "value": 18 } ], "tags": null, "organisation": { "id": 1, "slug": "opensafely", "name": "OpenSAFELY" }, "world_access": 1, "updated": "2026-01-26T23:09:26.273667Z", "references": [ { "url": "https://github.com/ebmdatalab/opensafely-codelist-development/issues/11", "title": "Discussion on GitHub issue" }, { "url": "https://bmjopen.bmj.com/content/10/1/e034886.long", "title": "Grint DJ, McDonald HI, Walker JL, et al. Safety of inadvertent administration of live zoster vaccine to immunosuppressed individuals in a UK-based observational cohort analysis. BMJ Open 2020;10:e034886." } ], "signed_off": [], "methodology": "This codelist was derived by the following method:\n\n\n- [Read 2 Codelist](https://github.com/ebmdatalab/tpp-sql-notebook/files/4409741/aplastic_anaemia_updated_Jul18.xlsx) provided by LSHTM. See reference for relevant paper.\n- Codes from Quality Outcome Framework (QOF) were examined and relevant aplastic anaemia codes taken\n- Codes from SNOMED were taken by searching for relevant aplastic anaemia terms\n\n\nThese 3 lists were mapped into CTV3 by TPP to create one list. This list was examined by 4 people and the following logic applied (see github issue for more detail):\n\n\n- Pure red cell aplasia excluded\n- Pancytopenia NOS was excluded from this list but included in the temporary immunosuppression list\n- T\\-cell mediated cytopenia excluded as it's thought to be a mechanism to cause aplastic anaemia but also possibly ITP and other single cell line reductions\n- Hypoplastic haemolytic and renal anaemia drugs excluded\n", "coding_system": [ { "name": "Read codes v3", "value": 6 } ], "open_codelist_id": "opensafely/aplastic-anaemia", "source_reference": "https://www.opencodelists.org/codelist/opensafely/aplastic-anaemia/2020-04-24", "concept_information": [ { "concept_id": 8453, "concept_version_id": 15938, "concept_name": "opensafely/aplastic-anaemia/2020-04-24", "coding_system": { "id": 6, "name": "Read codes v3", "description": "Read codes v3" }, "phenotype_id": "PH3283", "phenotype_version_id": 8276, "phenotype_name": "Aplastic Anaemia", "code_attribute_header": [ "CTV3Source" ], "codes": [ { "code": "D2...", "description": "Aplastic and other anaemias", "attributes": { "CTV3Source": "CTV3Map_Code_And_Term" } }, { "code": "D20..", "description": "Aplastic anaemia", "attributes": { "CTV3Source": "CTV3Map_Code_And_Term" } }, { "code": "D200.", "description": "(Anaem:[const aplas][fam hypopl])(pancytop+malf)(Black-Diam)", "attributes": { "CTV3Source": "CTV3_Children" } }, { "code": "D2000", "description": "Anaemia: [congen hypoplastic]/[constit aplastic, no malform]", "attributes": { "CTV3Source": "CTV3_Children" } }, { "code": "D2001", "description": "Fanconi's anaemia", "attributes": { "CTV3Source": "CTV3Map_Code_And_Term" } }, { "code": "D2003", "description": "(RBC aplas/hypoplas: [named variants]) or (Blackf-Diam synd)", "attributes": { "CTV3Source": "CTV3_Children" } }, { "code": "D200y", "description": "Other specified constitutional aplastic anaemia", "attributes": { "CTV3Source": "CTV3Map_Code_And_Term" } }, { "code": "D200z", "description": "Constitutional aplastic anaemia NOS", "attributes": { "CTV3Source": "CTV3_Children" } }, { "code": "D201.", "description": "Anaemia: [acquired aplastic] or [normocytic due to aplasia]", "attributes": { "CTV3Source": "CTV3_Children" } }, { "code": "D2010", "description": "Aplastic anaemia due to chronic disease", "attributes": { "CTV3Source": "CTV3Map_Code_And_Term" } }, { "code": "D2011", "description": "Anaemia: [aplast due drug][hypoplast due drug or chem subst]", "attributes": { "CTV3Source": "CTV3_Children" } }, { "code": "D2012", "description": "Aplastic anaemia due to infection", "attributes": { "CTV3Source": "CTV3Map_Code_And_Term" } }, { "code": "D2013", "description": "Aplastic anaemia due to radiation", "attributes": { "CTV3Source": "CTV3Map_Code_And_Term" } }, { "code": "D2014", "description": "Aplastic anaemia due to toxic cause", "attributes": { "CTV3Source": "CTV3Map_Code_And_Term" } }, { "code": "D2017", "description": "Transient hypoplastic anaemia", "attributes": { "CTV3Source": "CTV3_Children" } }, { "code": "D204.", "description": "Idiopathic aplastic anaemia", "attributes": { "CTV3Source": "CTV3Map_Code_And_Term" } }, { "code": "D20z.", "description": "Aplastic anaemia NOS", "attributes": { "CTV3Source": "CTV3Map_Code_And_Term" } }, { "code": "Dyu21", "description": "[X]Other specified aplastic anaemias", "attributes": { "CTV3Source": "CTV3_Children" } }, { "code": "X20CO", "description": "Pancytopenia with pancreatitis", "attributes": { "CTV3Source": "CTV3Map_Code_Only" } }, { "code": "X20CP", "description": "Constitutional aplastic anaemia without malformation", "attributes": { "CTV3Source": "CTV3Map_Code_And_Term" } }, { "code": "X30Jq", "description": "Congenital Fanconi syndrome", "attributes": { "CTV3Source": "CTV3Map_Code_And_Term" } }, { "code": "X30Jr", "description": "Acquired Fanconi syndrome", "attributes": { "CTV3Source": "CTV3Map_Code_And_Term" } }, { "code": "X30Js", "description": "Adult Fanconi syndrome", "attributes": { "CTV3Source": "CTV3Map_Code_And_Term" } }, { "code": "X70Jk", "description": "Parvoviral aplastic crisis", "attributes": { "CTV3Source": "QOF" } }, { "code": "XE13q", "description": "Constitutional aplastic anaemia", "attributes": { "CTV3Source": "CTV3Map_Code_And_Term" } }, { "code": "XE13r", "description": "Constitutional aplastic anaemia with malformation", "attributes": { "CTV3Source": "CTV3Map_Code_And_Term" } }, { "code": "XE13t", "description": "Acquired aplastic anaemia", "attributes": { "CTV3Source": "CTV3Map_Code_And_Term" } }, { "code": "XE13u", "description": "Aplastic anaemia due to drugs", "attributes": { "CTV3Source": "CTV3Map_Code_And_Term" } }, { "code": "XE13w", "description": "Acquired aplastic anaemia NOS", "attributes": { "CTV3Source": "CTV3Map_Code_And_Term" } }, { "code": "XE14g", "description": "Anaemia: [aplastic and other] or [aplastic] or [hypoblastic]", "attributes": { "CTV3Source": "High_Level_SNOMED" } }, { "code": "XM1Qy", "description": "Pancytopenia-dysmelia", "attributes": { "CTV3Source": "CTV3Map_Code_And_Term" } } ] } ], "coding_system_release": "", "open_codelist_version_id": "58ac196d", "open_codelist_version_tag": "2020-04-24", "status": 1, "doi": "https://doi.org/10.48533/zm6f-8w70", "is_deleted": false, "publish_status": 2, "owner": "ieuan.scanlon", "template": { "id": 3, "name": "OpenCodelists Phenotype", "description": "OpenSafely's OpenCodelist Phenotype, visit https://www.opencodelists.org/ to learn more", "version_id": 1 }, "versions": [ { "version_id": 8276, "version_name": "Aplastic Anaemia", "version_date": "2026-01-26T23:09:26.290938Z", "is_published": true, "is_latest": true } ] } ]