[
  {
    "phenotype_id": "PH3347",
    "phenotype_version_id": 8349,
    "name": "Advanced decompensated cirrhosis of the liver and associated conditions (ICD-10)",
    "definition": "This codelist was taken from [OpenCodelists](https://www.opencodelists.org/), created by [OpenSAFELY](https://www.opensafely.org/). We recommend viewing this Phenotype on the OpenCodelist website to view the most recent version.\n\n\nCodelist to identify patients with advanced decompensated cirrhosis of the liver.\n\n\nDecompensated cirrhosis is defined as an acute deterioration in liver function in a patient with cirrhosis and is characterised by jaundice, ascites, hepatic encephalopathy, hepatorenal syndrome or variceal haemorrhage. (Moreau et al, 2013\\)\n\n\nThe codelist takes into account the conditions which characterise advanced decompensated cirrhosis of the liver listed above as well as codes for cirrhosis.\n\n\nNote: This version does not include codes related to primary biliary cirrhosis. Additionally reviewer by Dr Karen Waller.\n\n\n© University of Oxford for the Bennett Institute for Applied Data Science 2025\\. This work may be copied freely for non\\-commercial research and study.\n\n",
    "implementation": null,
    "publications": null,
    "validation": null,
    "citation_requirements": null,
    "created": "2026-01-26T23:13:19.857197Z",
    "author": "OpenSAFELY",
    "collections": [
      {
        "name": "OpenCodelist",
        "value": 31
      },
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": {
      "id": 1,
      "slug": "opensafely",
      "name": "OpenSAFELY"
    },
    "world_access": 1,
    "updated": "2026-01-26T23:13:19.851860Z",
    "references": [
      {
        "url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267226/pdf/nihms646806.pdf",
        "title": "Validation of a coding algorithm to identify patients with end stage liver disease in an administrative database (Goldberg 2012)"
      },
      {
        "url": "https://www.gastrojournal.org/article/S0016-5085(13)00291-6/fulltext?referrer=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F",
        "title": "Acute-on-Chronic Liver Failure Is a Distinct Syndrome That Develops in Patients With Acute Decompensation of Cirrhosis (Moreau 2013)"
      },
      {
        "url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334027/pdf/clinmed-18-2s-s60.pdf",
        "title": "Management of decompensated cirrhosis (Mansour 2018)"
      }
    ],
    "signed_off": [],
    "methodology": "Methodology Search Terms: K70\\-77\n\n\nInclusion Criteria for Codes Terms for cirrhosis of the liver and for conditions that characterise an episode of decompensation.\n\n\nExclusion Criteria for Codes Jaundice not included\n\n\nBorderline Cases to Highlight: Codes describing acute hepatic injury \\- for example side effect of medication. May not capture the advanced nature of liver disease that looking to capture.\n\n",
    "coding_system": [
      {
        "name": "ICD10 codes",
        "value": 4
      }
    ],
    "open_codelist_id": "opensafely/condition-advanced-decompensated-cirrhosis-of-the-liver-and-associated-conditions-icd-10",
    "source_reference": "https://www.opencodelists.org/codelist/opensafely/condition-advanced-decompensated-cirrhosis-of-the-liver-and-associated-conditions-icd-10/00e40554",
    "concept_information": [
      {
        "concept_id": 8526,
        "concept_version_id": 16011,
        "concept_name": "opensafely/condition-advanced-decompensated-cirrhosis-of-the-liver-and-associated-conditions-icd-10/00e40554",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH3347",
        "phenotype_version_id": 8349,
        "phenotype_name": "Advanced decompensated cirrhosis of the liver and associated conditions (ICD-10)",
        "code_attribute_header": [],
        "codes": [
          {
            "code": "B150",
            "description": "Hepatitis A with hepatic coma",
            "attributes": null
          },
          {
            "code": "B160",
            "description": "Acute hepatitis B with delta-agent (coinfection) with hepatic coma",
            "attributes": null
          },
          {
            "code": "B162",
            "description": "Acute hepatitis B without delta-agent with hepatic coma",
            "attributes": null
          },
          {
            "code": "B190",
            "description": "Unspecified viral hepatitis with hepatic coma",
            "attributes": null
          },
          {
            "code": "I85",
            "description": "Oesophageal varices",
            "attributes": null
          },
          {
            "code": "I850",
            "description": "Oesophageal varices with bleeding",
            "attributes": null
          },
          {
            "code": "I859",
            "description": "Oesophageal varices without bleeding",
            "attributes": null
          },
          {
            "code": "I982",
            "description": "Oesophageal varices without bleeding in diseases classified elsewhere",
            "attributes": null
          },
          {
            "code": "I983",
            "description": "Oesophageal varices with bleeding in diseases classified elsewhere",
            "attributes": null
          },
          {
            "code": "K703",
            "description": "Alcoholic cirrhosis of liver",
            "attributes": null
          },
          {
            "code": "K717",
            "description": "Toxic liver disease with fibrosis and cirrhosis of liver",
            "attributes": null
          },
          {
            "code": "K74",
            "description": "Fibrosis and cirrhosis of liver",
            "attributes": null
          },
          {
            "code": "K743",
            "description": "Primary biliary cirrhosis",
            "attributes": null
          },
          {
            "code": "K744",
            "description": "Secondary biliary cirrhosis",
            "attributes": null
          },
          {
            "code": "K745",
            "description": "Biliary cirrhosis, unspecified",
            "attributes": null
          },
          {
            "code": "K746",
            "description": "Other and unspecified cirrhosis of liver",
            "attributes": null
          },
          {
            "code": "K766",
            "description": "Portal hypertension",
            "attributes": null
          },
          {
            "code": "K767",
            "description": "Hepatorenal syndrome",
            "attributes": null
          },
          {
            "code": "R18",
            "description": "Ascites",
            "attributes": null
          }
        ]
      }
    ],
    "coding_system_release": "",
    "open_codelist_version_id": "00e40554",
    "open_codelist_version_tag": "",
    "status": 1,
    "doi": "https://doi.org/10.48533/73gw-9109",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 3,
      "name": "OpenCodelists Phenotype",
      "description": "OpenSafely's OpenCodelist Phenotype, visit https://www.opencodelists.org/ to learn more",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 8349,
        "version_name": "Advanced decompensated cirrhosis of the liver and associated conditions (ICD-10)",
        "version_date": "2026-01-26T23:13:19.867714Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]