[
  {
    "phenotype_id": "PH3452",
    "phenotype_version_id": 8494,
    "name": "High dose multiple ingredient ICS inhalers",
    "definition": "This codelist was taken from [OpenCodelists](https://www.opencodelists.org/), created by [OpenSAFELY](https://www.opensafely.org/). We recommend viewing this Phenotype on the OpenCodelist website to view the most recent version.\n\n\nA list of high dose inhaled corticosteroid (ICS) preparations at VMP and AMP from the NHS Dictionary of Medicines and Devices.\n\n\n© University of Oxford for the Bennett Institute for Applied Data Science 2025\\. This work may be copied freely for non\\-commercial research and study.\n\n",
    "implementation": null,
    "publications": null,
    "validation": null,
    "citation_requirements": null,
    "created": "2026-01-26T23:18:03.578007Z",
    "author": "OpenSAFELY",
    "collections": [
      {
        "name": "OpenCodelist",
        "value": 31
      },
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": {
      "id": 1,
      "slug": "opensafely",
      "name": "OpenSAFELY"
    },
    "world_access": 1,
    "updated": "2026-01-26T23:18:03.572329Z",
    "references": [
      {
        "url": "https://github.com/ebmdatalab/steroids-covid-codelist-notebook/blob/master/notebooks/highdose.inhaled.steroids.combi.agent.ipynb",
        "title": "Jupyter Notebook"
      },
      {
        "url": "https://github.com/ebmdatalab/opensafely-ics-research/issues/25",
        "title": "GitHub discussion"
      }
    ],
    "signed_off": [],
    "methodology": "This codelist is based on the OpenPrescribing.net measure of prescribing of high dose ICS which itself is derived from British Thoracic/SIGN guidance. It includes\n\n\n- Inhalers where form\\-route is `pressurizedinhalation.inhalation` OR `powderinhalation.inhalation`\n\n\nand\n\n\n- BNF codes related to ICS of multi\\-ingredient preparation. Full details of BNF codes iincluded can be read in the Jupyter noptebook below.\n",
    "coding_system": [
      {
        "name": "dm+d codes",
        "value": 23
      }
    ],
    "open_codelist_id": "opensafely/high-dose-multiple-ingredient-ics-inhalers",
    "source_reference": "https://www.opencodelists.org/codelist/opensafely/high-dose-multiple-ingredient-ics-inhalers/2020-05-13",
    "concept_information": [
      {
        "concept_id": 8671,
        "concept_version_id": 16156,
        "concept_name": "opensafely/high-dose-multiple-ingredient-ics-inhalers/2020-05-13",
        "coding_system": {
          "id": 23,
          "name": "dm+d codes",
          "description": "dm+d codes"
        },
        "phenotype_id": "PH3452",
        "phenotype_version_id": 8494,
        "phenotype_name": "High dose multiple ingredient ICS inhalers",
        "code_attribute_header": [
          "id",
          "type",
          "bnf_code"
        ],
        "codes": [
          {
            "code": "21019711000001107",
            "description": "Flutiform 250micrograms/dose / 10micrograms/dose inhaler (Napp Pharmaceuticals Ltd)",
            "attributes": {
              "id": "21019711000001107",
              "type": "amp",
              "bnf_code": "0302000N0BDABBK"
            }
          },
          {
            "code": "21113811000001105",
            "description": "Fluticasone 250micrograms/dose / Formoterol 10micrograms/dose inhaler CFC free",
            "attributes": {
              "id": "21113811000001105",
              "type": "vmp",
              "bnf_code": "0302000N0AABKBK"
            }
          },
          {
            "code": "23621711000001102",
            "description": "Relvar Ellipta 184micrograms/dose / 22micrograms/dose dry powder inhaler (GlaxoSmithKline UK Ltd)",
            "attributes": {
              "id": "23621711000001102",
              "type": "amp",
              "bnf_code": "0302000V0BBAAAA"
            }
          },
          {
            "code": "23661311000001105",
            "description": "Fluticasone furoate 184micrograms/dose / Vilanterol 22micrograms/dose dry powder inhaler",
            "attributes": {
              "id": "23661311000001105",
              "type": "vmp",
              "bnf_code": "0302000V0AAAAAA"
            }
          },
          {
            "code": "25254711000001106",
            "description": "DuoResp Spiromax 320micrograms/dose / 9micrograms/dose dry powder inhaler (Teva UK Ltd)",
            "attributes": {
              "id": "25254711000001106",
              "type": "amp",
              "bnf_code": "0302000K0BHABAU"
            }
          },
          {
            "code": "29782511000001103",
            "description": "Sirdupla 25micrograms/dose / 250micrograms/dose inhaler (Mylan)",
            "attributes": {
              "id": "29782511000001103",
              "type": "amp",
              "bnf_code": "0302000N0BFABBG"
            }
          },
          {
            "code": "30950311000001106",
            "description": "AirFluSal Forspiro 50micrograms/dose / 500micrograms/dose dry powder inhaler (Sandoz Ltd)",
            "attributes": {
              "id": "30950311000001106",
              "type": "amp",
              "bnf_code": "0302000N0BGAAAZ"
            }
          },
          {
            "code": "31063111000001106",
            "description": "Fostair NEXThaler 200micrograms/dose / 6micrograms/dose dry powder inhaler (Chiesi Ltd)",
            "attributes": {
              "id": "31063111000001106",
              "type": "amp",
              "bnf_code": "0302000C0BRABCA"
            }
          },
          {
            "code": "31063411000001101",
            "description": "Fostair 200micrograms/dose / 6micrograms/dose inhaler (Chiesi Ltd)",
            "attributes": {
              "id": "31063411000001101",
              "type": "amp",
              "bnf_code": "0302000C0BQABBZ"
            }
          },
          {
            "code": "31064811000001101",
            "description": "Fluticasone propionate 500micrograms/dose / Salmeterol 50micrograms/dose dry powder inhaler (A A H Pharmaceuticals Ltd)",
            "attributes": {
              "id": "31064811000001101",
              "type": "amp",
              "bnf_code": "0302000N0AAAZAZ"
            }
          },
          {
            "code": "31087411000001106",
            "description": "Beclometasone 200micrograms/dose / Formoterol 6micrograms/dose inhaler CFC free",
            "attributes": {
              "id": "31087411000001106",
              "type": "vmp",
              "bnf_code": "0302000C0AABZBZ"
            }
          },
          {
            "code": "31087511000001105",
            "description": "Beclometasone 200micrograms/dose / Formoterol 6micrograms/dose dry powder inhaler",
            "attributes": {
              "id": "31087511000001105",
              "type": "vmp",
              "bnf_code": "0302000C0AACACA"
            }
          },
          {
            "code": "3188311000001102",
            "description": "Seretide 500 Accuhaler (GlaxoSmithKline UK Ltd)",
            "attributes": {
              "id": "3188311000001102",
              "type": "amp",
              "bnf_code": "0302000N0BCACAZ"
            }
          },
          {
            "code": "320276009",
            "description": "Fluticasone 250micrograms/dose / Salmeterol 25micrograms/dose inhaler CFC free",
            "attributes": {
              "id": "320276009",
              "type": "vmp",
              "bnf_code": "0302000N0AABGBG"
            }
          },
          {
            "code": "320280004",
            "description": "Fluticasone propionate 500micrograms/dose / Salmeterol 50micrograms/dose dry powder inhaler",
            "attributes": {
              "id": "320280004",
              "type": "vmp",
              "bnf_code": "0302000N0AAAZAZ"
            }
          },
          {
            "code": "33679711000001103",
            "description": "Aerivio Spiromax 50micrograms/dose / 500micrograms/dose dry powder inhaler (Teva UK Ltd)",
            "attributes": {
              "id": "33679711000001103",
              "type": "amp",
              "bnf_code": "0302000N0BHAAAZ"
            }
          },
          {
            "code": "34023811000001102",
            "description": "Sereflo 25micrograms/dose / 250micrograms/dose inhaler (Cipla EU Ltd)",
            "attributes": {
              "id": "34023811000001102",
              "type": "amp",
              "bnf_code": "0302000N0BIABBG"
            }
          },
          {
            "code": "34215511000001101",
            "description": "AirFluSal 25micrograms/dose / 250micrograms/dose inhaler (Sandoz Ltd)",
            "attributes": {
              "id": "34215511000001101",
              "type": "amp",
              "bnf_code": "0302000N0BGACBG"
            }
          },
          {
            "code": "34675711000001103",
            "description": "Aloflute 25micrograms/dose / 250micrograms/dose inhaler (Mylan)",
            "attributes": {
              "id": "34675711000001103",
              "type": "amp",
              "bnf_code": "0302000N0BJABBG"
            }
          },
          {
            "code": "34812111000001106",
            "description": "Fobumix Easyhaler 320micrograms/dose / 9micrograms/dose dry powder inhaler (Orion Pharma (UK) Ltd)",
            "attributes": {
              "id": "34812111000001106",
              "type": "amp",
              "bnf_code": "0302000K0BIAAAU"
            }
          },
          {
            "code": "35515311000001106",
            "description": "Fusacomb Easyhaler 50micrograms/dose / 500micrograms/dose dry powder inhaler (Orion Pharma (UK) Ltd)",
            "attributes": {
              "id": "35515311000001106",
              "type": "amp",
              "bnf_code": "0302000N0BKABAZ"
            }
          },
          {
            "code": "35594411000001101",
            "description": "Combisal 25micrograms/dose / 250micrograms/dose inhaler (Aspire Pharma Ltd)",
            "attributes": {
              "id": "35594411000001101",
              "type": "amp",
              "bnf_code": "0302000N0BLACBG"
            }
          },
          {
            "code": "36604711000001102",
            "description": "Stalpex 50micrograms/dose / 500micrograms/dose dry powder inhaler (Glenmark Pharmaceuticals Europe Ltd)",
            "attributes": {
              "id": "36604711000001102",
              "type": "amp",
              "bnf_code": "0302000N0BMAAAZ"
            }
          },
          {
            "code": "38897411000001103",
            "description": "VMP subsequent to 320280004",
            "attributes": {
              "id": "38897411000001103",
              "type": "vmp",
              "bnf_code": "0302000N0AAAZAZ"
            }
          },
          {
            "code": "39111311000001106",
            "description": "VMP subsequent to 320276009",
            "attributes": {
              "id": "39111311000001106",
              "type": "vmp",
              "bnf_code": "0302000N0AABGBG"
            }
          },
          {
            "code": "4373811000001100",
            "description": "Symbicort 400/12 Turbohaler (AstraZeneca UK Ltd)",
            "attributes": {
              "id": "4373811000001100",
              "type": "amp",
              "bnf_code": "0302000K0BDACAU"
            }
          },
          {
            "code": "4378111000001103",
            "description": "Budesonide 400micrograms/dose / Formoterol 12micrograms/dose dry powder inhaler",
            "attributes": {
              "id": "4378111000001103",
              "type": "vmp",
              "bnf_code": "0302000K0AAAUAU"
            }
          },
          {
            "code": "539811000001106",
            "description": "Seretide 250 Evohaler (GlaxoSmithKline UK Ltd)",
            "attributes": {
              "id": "539811000001106",
              "type": "amp",
              "bnf_code": "0302000N0BCAFBG"
            }
          }
        ]
      }
    ],
    "coding_system_release": "",
    "open_codelist_version_id": "527fe5f2",
    "open_codelist_version_tag": "2020-05-13",
    "status": 1,
    "doi": "https://doi.org/10.48533/fpe1-jc77",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 3,
      "name": "OpenCodelists Phenotype",
      "description": "OpenSafely's OpenCodelist Phenotype, visit https://www.opencodelists.org/ to learn more",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 8494,
        "version_name": "High dose multiple ingredient ICS inhalers",
        "version_date": "2026-01-26T23:18:03.590189Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]