[
  {
    "phenotype_id": "PH350",
    "phenotype_version_id": 1513,
    "name": "Smoking Status",
    "definition": "The most recent smoking record before study entry was used to classify individuals as never, ex- or current smokers, and those identified as current smokers with no smoking record within the 3 years before study entry were reclassified as having missing smoking data. Never smokers who had a record of smoking at any time before baseline were reclassified as ex-smokers.\n\n\n\n\n\n\n\n\n\n\n",
    "implementation": "",
    "publications": [
      {
        "doi": "10.1136/bmjopen-2017-018331",
        "details": "Gho JMIH et al. An electronic health records cohort study on heart failure following myocardial infarction in England: incidence and predictors. BMJ Open. 2018 Mar 3;8(3):e018331. doi: 10.1136/bmjopen-2017-018331. PMID: 29502083"
      },
      {
        "doi": "10.1371/journal.pone.0202344",
        "details": "Steele AJ et al. Machine learning models in electronic health records can outperform conventional survival models for predicting patient mortality in coronary artery disease. PLoS One. 2018 Aug 31;13(8):e0202344. doi: 10.1371/journal.pone.0202344. eCollection 2018. PMID: 30169498"
      },
      {
        "doi": "10.1177/2047487318785228",
        "details": "Archangelidi O et al. Clinically recorded heart rate and incidence of 12 coronary, cardiac, cerebrovascular and peripheral arterial diseases in 233,970 men and women: A linked electronic health record study. Eur J Prev Cardiol. 2018 Sep;25(14):1485-1495. doi: 10.1177/2047487318785228. Epub 2018 Jul 2. PMID: 29966429"
      },
      {
        "doi": "10.1002/ejhf.709",
        "details": "Koudstaal S et al. Prognostic burden of heart failure recorded in primary care, acute hospital admissions, or both: a population-based linked electronic health record cohort study in 2.1 million people. Eur J Heart Fail. 2017 Sep;19(9):1119-1127. doi: 10.1002/ejhf.709. Epub 2016 Dec 23. PMID: 28008698"
      },
      {
        "doi": "10.1371/journal.pone.0202359",
        "details": "Chung SC et al. Time spent at blood pressure target and the risk of death and cardiovascular diseases. PLoS One. 2018 Sep 5;13(9):e0202359. doi: 10.1371/journal.pone.0202359. eCollection 2018. PMID: 30183734"
      },
      {
        "doi": null,
        "details": "Bell S et al. Association between clinically recorded alcohol consumption and initial presentation of 12 cardiovascular diseases: population based cohort study using linked health records. BMJ. 2017 Mar 22;356:j909. PMID: 28331015"
      },
      {
        "doi": "10.1093/eurheartj/ehw683",
        "details": "Pasea L et al. Personalising the decision for prolonged dual antiplatelet therapy: development, validation and potential impact of prognostic models for cardiovascular events and bleeding in myocardial infarction survivors. Eur Heart J. 2017 Apr 7;38(14):1048-1055. doi: 10.1093/eurheartj/ehw683. PMID: 28329300"
      },
      {
        "doi": "10.1016/j.jacc.2016.12.022",
        "details": "Shah AD et al. Neutrophil Counts and Initial Presentation of 12 Cardiovascular Diseases: A CALIBER Cohort Study. J Am Coll Cardiol. 2017 Mar 7;69(9):1160-1169. doi: 10.1016/j.jacc.2016.12.022. PMID: 28254179"
      },
      {
        "doi": "10.1136/heartjnl-2015-308850",
        "details": "Asaria M et al. Using electronic health records to predict costs and outcomes in stable coronary artery disease. Heart. 2016 May 15;102(10):755-62. doi: 10.1136/heartjnl-2015-308850. Epub 2016 Feb 10. PMID: 26864674"
      },
      {
        "doi": "10.1371/journal.pone.0153838",
        "details": "Daskalopoulou M et al. Depression as a Risk Factor for the Initial Presentation of Twelve Cardiac, Cerebrovascular, and Peripheral Arterial Diseases: Data Linkage Study of 1.9 Million Women and Men. PLoS One. 2016 Apr 22;11(4):e0153838. doi: 10.1371/journal.pone.0153838. eCollection 2016. PMID: 27105076"
      },
      {
        "doi": "10.1136/heartjnl-2015-308514",
        "details": "Pujades-Rodriguez M et al. Associations between polymyalgia rheumatica and giant cell arteritis and 12 cardiovascular diseases. Heart. 2016 Mar;102(5):383-9. doi: 10.1136/heartjnl-2015-308514. Epub 2016 Jan 19. PMID: 26786818"
      },
      {
        "doi": "10.1371/journal.pone.0151245",
        "details": "Pujades-Rodriguez M et al. Rheumatoid Arthritis and Incidence of Twelve Initial Presentations of Cardiovascular Disease: A Population Record-Linkage Cohort Study in England. PLoS One. 2016 Mar 15;11(3):e0151245. doi: 10.1371/journal.pone.0151245. eCollection 2016. PMID: 26978266"
      },
      {
        "doi": "10.1136/openhrt-2016-000477",
        "details": "Shah AD et al. Low eosinophil and low lymphocyte counts and the incidence of 12 cardiovascular diseases: a CALIBER cohort study. Open Heart. 2016 Sep 5;3(2):e000477. doi: 10.1136/openhrt-2016-000477. eCollection 2016. PMID: 27621833"
      },
      {
        "doi": null,
        "details": "Timmis A et al. Prolonged dual antiplatelet therapy in stable coronary disease: comparative observational study of benefits and harms in unselected versus trial populations. BMJ. 2016 Jun 22;353:i3163. PMID: 27334486"
      },
      {
        "doi": "10.1093/ehjqcco/qcw003",
        "details": "Walker S et al. Long-term healthcare use and costs in patients with stable coronary artery disease: a population-based cohort using linked health records (CALIBER). Eur Heart J Qual Care Clin Outcomes. 2016 Jan 20;2(2):125-140. doi: 10.1093/ehjqcco/qcw003. PMID: 27042338"
      },
      {
        "doi": "10.1161/CIRCULATIONAHA.114.013797",
        "details": "George J et al. How Does Cardiovascular Disease First Present in Women and Men? Incidence of 12 Cardiovascular Diseases in a Contemporary Cohort of 1,937,360 People. Circulation. 2015 Oct 6;132(14):1320-8. doi: 10.1161/CIRCULATIONAHA.114.013797. Epub 2015 Sep 1. PMID: 26330414"
      },
      {
        "doi": "10.1371/journal.pone.0110900",
        "details": "Morley KI et al. Defining disease phenotypes using national linked electronic health records: a case study of atrial fibrillation. PLoS One. 2014 Nov 4;9(11):e110900. doi: 10.1371/journal.pone.0110900. eCollection 2014. PMID: 25369203"
      },
      {
        "doi": "10.1093/ije/dyu218",
        "details": "Pujades-Rodriguez M et al. Heterogeneous associations between smoking and a wide range of initial presentations of cardiovascular disease in 1937360 people in England: lifetime risks and implications for risk prediction. Int J Epidemiol. 2015 Feb;44(1):129-41. doi: 10.1093/ije/dyu218. Epub 2014 Nov 20. PMID: 25416721"
      },
      {
        "doi": "10.1371/journal.pone.0104671",
        "details": "Pujades-Rodriguez M et al. Socioeconomic deprivation and the incidence of 12 cardiovascular diseases in 1.9 million women and men: implications for risk prediction and prevention. PLoS One. 2014 Aug 21;9(8):e104671. doi: 10.1371/journal.pone.0104671. eCollection 2014. PMID: 25144739"
      },
      {
        "doi": "10.1016/S0140-6736(14)60685-1",
        "details": "Rapsomaniki E et al. Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1.25 million people. Lancet. 2014 May 31;383(9932):1899-911. doi: 10.1016/S0140-6736(14)60685-1. PMID: 24881994"
      },
      {
        "doi": "10.1016/S2213-8587(14)70219-0",
        "details": "Shah AD et al. Type 2 diabetes and incidence of cardiovascular diseases: a cohort study in 1.9 million people. Lancet Diabetes Endocrinol. 2015 Feb;3(2):105-13. doi: 10.1016/S2213-8587(14)70219-0. Epub 2014 Nov 11. PMID: 25466521"
      },
      {
        "doi": "10.1093/eurheartj/eht533",
        "details": "Rapsomaniki E et al. Prognostic models for stable coronary artery disease based on electronic health record cohort of 102 023 patients. Eur Heart J. 2014 Apr;35(13):844-52. doi: 10.1093/eurheartj/eht533. Epub 2013 Dec 17. PMID: 24353280"
      }
    ],
    "validation": "",
    "citation_requirements": "",
    "created": "2021-10-06T16:14:28.782944Z",
    "author": "Julie George, Emily Herrett, Liam Smeeth, Harry Hemingway, Anoop Shah, Spiros Denaxas",
    "collections": [
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": null,
    "world_access": 1,
    "updated": "2021-10-19T13:52:12.353426Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Lifestyle risk factor",
        "value": "4"
      }
    ],
    "ontology": null,
    "phenoflowid": "https://kclhi.org/phenoflow/workflows/github.com/phenoflow/Smoking-Status---0f05ece0-1833-11ef-9de4-4d4ea830ad16/blob/read-potential-cases-fhir/Smoking-Status.cwl",
    "data_sources": [
      {
        "name": "CPRD GOLD",
        "value": 5,
        "uid": "a29feafa-7bdd-44e9-b977-c9d26425e67f",
        "url": "https://healthdatagateway.org/en/dataset/694",
        "datasource_id": 694
      }
    ],
    "coding_system": [
      {
        "name": "ICD10 codes",
        "value": 4
      },
      {
        "name": "Read codes v2",
        "value": 5
      }
    ],
    "event_date_range": "01/01/1999 - 01/07/2016",
    "concept_information": [
      {
        "concept_id": 1678,
        "concept_version_id": 5500,
        "concept_name": "Smoking Status - Primary Care",
        "coding_system": {
          "id": 5,
          "name": "Read codes v2",
          "description": "Read codes v2"
        },
        "phenotype_id": "PH350",
        "phenotype_version_id": 1513,
        "phenotype_name": "Smoking Status",
        "code_attribute_header": [
          "CALIBER category"
        ],
        "codes": [
          {
            "code": "1371",
            "description": "Never smoked tobacco",
            "attributes": {
              "CALIBER category": "Non smoker"
            }
          },
          {
            "code": "1371.11",
            "description": "Non-smoker",
            "attributes": {
              "CALIBER category": "Non smoker"
            }
          },
          {
            "code": "1377",
            "description": "Ex-trivial smoker (<1/day)",
            "attributes": {
              "CALIBER category": "Ex smoker"
            }
          },
          {
            "code": "1378",
            "description": "Ex-light smoker (1-9/day)",
            "attributes": {
              "CALIBER category": "Ex smoker"
            }
          },
          {
            "code": "1379",
            "description": "Ex-moderate smoker (10-19/day)",
            "attributes": {
              "CALIBER category": "Ex smoker"
            }
          },
          {
            "code": "137A.00",
            "description": "Ex-heavy smoker (20-39/day)",
            "attributes": {
              "CALIBER category": "Ex smoker"
            }
          },
          {
            "code": "137B.00",
            "description": "Ex-very heavy smoker (40+/day)",
            "attributes": {
              "CALIBER category": "Ex smoker"
            }
          },
          {
            "code": "137F.00",
            "description": "Ex-smoker - amount unknown",
            "attributes": {
              "CALIBER category": "Ex smoker"
            }
          },
          {
            "code": "137j.00",
            "description": "Ex-cigarette smoker",
            "attributes": {
              "CALIBER category": "Ex smoker"
            }
          },
          {
            "code": "137K.00",
            "description": "Stopped smoking",
            "attributes": {
              "CALIBER category": "Ex smoker"
            }
          },
          {
            "code": "137L.00",
            "description": "Current non-smoker",
            "attributes": {
              "CALIBER category": "Non smoker"
            }
          },
          {
            "code": "137N.00",
            "description": "Ex pipe smoker",
            "attributes": {
              "CALIBER category": "Ex smoker"
            }
          },
          {
            "code": "137O.00",
            "description": "Ex cigar smoker",
            "attributes": {
              "CALIBER category": "Ex smoker"
            }
          },
          {
            "code": "137S.00",
            "description": "Ex smoker",
            "attributes": {
              "CALIBER category": "Ex smoker"
            }
          },
          {
            "code": "137T.00",
            "description": "Date ceased smoking",
            "attributes": {
              "CALIBER category": "Ex smoker"
            }
          },
          {
            "code": "13WK.00",
            "description": "No smokers in the household",
            "attributes": {
              "CALIBER category": "Non smoker"
            }
          },
          {
            "code": "9km..00",
            "description": "Ex-smoker annual review - enhanced services administration",
            "attributes": {
              "CALIBER category": "Ex smoker"
            }
          },
          {
            "code": "9kn..00",
            "description": "Non-smoker annual review - enhanced services administration",
            "attributes": {
              "CALIBER category": "Non smoker"
            }
          },
          {
            "code": "E251300",
            "description": "Tobacco dependence in remission",
            "attributes": {
              "CALIBER category": "Ex smoker"
            }
          },
          {
            "code": "H310100",
            "description": "Smokers' cough",
            "attributes": {
              "CALIBER category": "Ex or current smoker"
            }
          },
          {
            "code": "ZV11600",
            "description": "[V]Personal history of tobacco abuse",
            "attributes": {
              "CALIBER category": "Ex or current smoker"
            }
          }
        ]
      },
      {
        "concept_id": 1679,
        "concept_version_id": 5501,
        "concept_name": "Smoking Status - Secondary care",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH350",
        "phenotype_version_id": 1513,
        "phenotype_name": "Smoking Status",
        "code_attribute_header": [
          "CALIBER category"
        ],
        "codes": [
          {
            "code": "F17",
            "description": "Mental and behavioural disorders due to use of tobacco",
            "attributes": {
              "CALIBER category": "Current smoker"
            }
          },
          {
            "code": "Z716",
            "description": "Tobacco abuse counselling",
            "attributes": {
              "CALIBER category": "Current smoker"
            }
          },
          {
            "code": "Z720",
            "description": "Tobacco use",
            "attributes": {
              "CALIBER category": "Current smoker"
            }
          }
        ]
      }
    ],
    "status": 2,
    "doi": "https://doi.org/10.48533/c2kp-1p53",
    "is_deleted": null,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 1,
      "name": "Clinical-Coded Phenotype",
      "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 1513,
        "version_name": "Smoking Status",
        "version_date": "2021-10-19T13:52:12.573955Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]