[ { "phenotype_id": "PH354", "phenotype_version_id": 708, "name": "Angina", "definition": "Methods: \n\nData were drawn from the UK General Practice Research Database. Analyses evaluated the occurrence of 271 READ medical diagnostic codes, including categories for ‘Angina’, ‘Myocardial Infarction’, ‘Coronary Artery Bypass Grafting’ (CABG), ‘percutaneous transluminal coronary angioplasty’ (PCTA) and ‘Other Coronary Heart Disease’. Time-to-event analyses were implemented to evaluate occurrences of different groups of codes after the index date.\n\n\nResults: \n\nAmong 300,020 participants aged greater than 30 years there were 75,197 unique occurrences of coronary heart disease codes in 24,244 participants, with 12,495 codes for incident events and 62,702 for prevalent events. Among incident event codes, 3,607 (28.87%) were for angina, 3,262 (26.11%) were for MI, 514 (4.11%) for PCTA, 161 (1.29%) for CABG and 4,951 (39.62%) were for ‘Other CHD’. Among prevalent codes, 20,254 (32.30%) were for angina, 3,644 (5.81%) for MI, 34,542 (55.09%) for ‘Other CHD’ and 4,262 (6.80%) for CABG or PCTA. Among 3,685 participants initially diagnosed exclusively with ‘Other CHD’ codes, 17.1% were recorded with angina within 5 years, 5.6% with myocardial infarction, 6.3% with CABG and 8.6% with PCTA. From 2000 to 2010, the overall incidence of CHD declined, as did the incidence of angina, but the incidence of MI did not change. The frequency of CABG declined, while PCTA increased.\n\n\n\n\n\n\n\n\n", "implementation": "", "publications": [ { "doi": null, "details": "Nawarj Bhattarai, Judith Charlton, Caroline Rudisill, Martin C Gulliford, Coding, Recording and Incidence of Different Forms of Coronary Heart Disease in Primary Care. PLoS ONE, 7:1, 2012." } ], "validation": "", "citation_requirements": "", "created": "2021-10-06T16:15:28.454048Z", "author": "Nawaraj Bhattarai, Judith Charlton, Caroline Rudisill, Martin C Gulliford", "collections": [ { "name": "ClinicalCodes Repository", "value": 25 }, { "name": "Phenotype Library", "value": 18 } ], "tags": null, "organisation": null, "world_access": 1, "updated": "2021-10-06T16:15:28.454077Z", "sex": [ { "name": "Both", "value": "3" } ], "type": [ { "name": "Disease or syndrome", "value": "2" } ], "ontology": null, "phenoflowid": "", "data_sources": [ { "name": "CPRD GOLD", "value": 5, "uid": "a29feafa-7bdd-44e9-b977-c9d26425e67f", "url": "https://healthdatagateway.org/en/dataset/694", "datasource_id": 694 } ], "coding_system": [ { "name": "Read codes v2", "value": 5 } ], "event_date_range": "01/01/2004 - 30/06/2010", "concept_information": [ { "concept_id": 1683, "concept_version_id": 4504, "concept_name": "Angina - Primary Care", "coding_system": { "id": 5, "name": "Read codes v2", "description": "Read codes v2" }, "phenotype_id": "PH354", "phenotype_version_id": 708, "phenotype_name": "Angina", "code_attribute_header": [ "Entity type", "Category", "Coding System (Read)" ], "codes": [ { "code": "14A5.00", "description": "H/O: angina pectoris", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "14AJ.00", "description": "H/O: Angina in last year", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "662K.00", "description": "Angina control", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "662K000", "description": "Angina control - good", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "662K100", "description": "Angina control - poor", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "662K200", "description": "Angina control - improving", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "662K300", "description": "Angina control - worsening", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "662Kz00", "description": "Angina control NOS", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "8B27.00", "description": "Antianginal therapy", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G311000", "description": "Myocardial infarction aborted", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G311100", "description": "Unstable angina", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G311.11", "description": "Crescendo angina", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G311.13", "description": "Unstable angina", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G311.14", "description": "Angina at rest", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G311200", "description": "Angina at rest", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G311300", "description": "Refractory angina", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G311400", "description": "Worsening angina", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G311500", "description": "Acute coronary syndrome", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G31y000", "description": "Acute coronary insufficiency", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G33..00", "description": "Angina pectoris", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G330.00", "description": "Angina decubitus", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G330000", "description": "Nocturnal angina", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G330z00", "description": "Angina decubitus NOS", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G331.00", "description": "Prinzmetal's angina", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G331.11", "description": "Variant angina pectoris", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G33z.00", "description": "Angina pectoris NOS", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G33z200", "description": "Syncope anginosa", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G33z300", "description": "Angina on effort", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G33z400", "description": "Ischaemic chest pain", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G33z500", "description": "Post infarct angina", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G33z600", "description": "New onset angina", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G33z700", "description": "Stable angina", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G33zz00", "description": "Angina pectoris NOS", "attributes": { "Entity type": "res12: Angina", "Category": "diagnostic", "Coding System (Read)": "Read" } } ] } ], "status": 2, "doi": "https://doi.org/10.48533/6hk2-4049", "is_deleted": null, "publish_status": 2, "owner": "ieuan.scanlon", "template": { "id": 1, "name": "Clinical-Coded Phenotype", "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.", "version_id": 1 }, "versions": [ { "version_id": 708, "version_name": "Angina", "version_date": "2021-10-06T16:15:28.475975Z", "is_published": true, "is_latest": true } ] } ]