[
  {
    "phenotype_id": "PH3630",
    "phenotype_version_id": 8729,
    "name": "Permanent Immunosuppression",
    "definition": "This codelist was taken from [OpenCodelists](https://www.opencodelists.org/), created by [OpenSAFELY](https://www.opensafely.org/). We recommend viewing this Phenotype on the OpenCodelist website to view the most recent version.\n\n\nCodes indicating a diagnosis of a permanent immunosuppression excluding HIV, and including genetic causes of immunosuppression\n\n\n© University of Oxford for the Bennett Institute for Applied Data Science 2025\\. This work may be copied freely for non\\-commercial research and study.\n\n",
    "implementation": null,
    "publications": null,
    "validation": null,
    "citation_requirements": null,
    "created": "2026-01-26T23:27:12.978953Z",
    "author": "OpenSAFELY",
    "collections": [
      {
        "name": "OpenCodelist",
        "value": 31
      },
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": {
      "id": 1,
      "slug": "opensafely",
      "name": "OpenSAFELY"
    },
    "world_access": 1,
    "updated": "2026-01-26T23:27:12.972244Z",
    "references": [
      {
        "url": "https://github.com/ebmdatalab/opensafely-codelist-development/issues/11",
        "title": "Discussion on GitHub issue"
      }
    ],
    "signed_off": [],
    "methodology": "TODO\n\n",
    "coding_system": [
      {
        "name": "Read codes v3",
        "value": 6
      }
    ],
    "open_codelist_id": "opensafely/permanent-immunosuppression",
    "source_reference": "https://www.opencodelists.org/codelist/opensafely/permanent-immunosuppression/2020-06-02",
    "concept_information": [
      {
        "concept_id": 8906,
        "concept_version_id": 16391,
        "concept_name": "opensafely/permanent-immunosuppression/2020-06-02",
        "coding_system": {
          "id": 6,
          "name": "Read codes v3",
          "description": "Read codes v3"
        },
        "phenotype_id": "PH3630",
        "phenotype_version_id": 8729,
        "phenotype_name": "Permanent Immunosuppression",
        "code_attribute_header": [],
        "codes": [
          {
            "code": "8C31.",
            "description": "Transplant immunosuppression",
            "attributes": null
          },
          {
            "code": "C30yy",
            "description": "(Adenosine deamin def) or (oth sp disturb amino acid metab)",
            "attributes": null
          },
          {
            "code": "C3760",
            "description": "C1 esterase inhibitor deficiency",
            "attributes": null
          },
          {
            "code": "C390.",
            "description": "(Deficiencies of humoral immunity) or (agammaglobulinaemia)",
            "attributes": null
          },
          {
            "code": "C3901",
            "description": "Selective immunoglobulin A deficiency",
            "attributes": null
          },
          {
            "code": "C3902",
            "description": "Selective immunoglobulin M deficiency",
            "attributes": null
          },
          {
            "code": "C3903",
            "description": "Selective immunoglobulin G deficiency",
            "attributes": null
          },
          {
            "code": "C3904",
            "description": "Other selective immunoglobulin deficiency",
            "attributes": null
          },
          {
            "code": "C3905",
            "description": "Hypogammaglob:[cong][agammaglob:(Brut)(cong sex-link &amp; [X])]",
            "attributes": null
          },
          {
            "code": "C3906",
            "description": "Hyperimmunoglobulin M syndrome",
            "attributes": null
          },
          {
            "code": "C3907",
            "description": "Common variable immunodeficiency",
            "attributes": null
          },
          {
            "code": "C3909",
            "description": "Agammaglobulinaemia NEC",
            "attributes": null
          },
          {
            "code": "C390A",
            "description": "Dysimmunoglobulinaemia NEC",
            "attributes": null
          },
          {
            "code": "C390y",
            "description": "Other specified deficiency of humoral immunity",
            "attributes": null
          },
          {
            "code": "C390z",
            "description": "Deficiency of humoral immunity NOS",
            "attributes": null
          },
          {
            "code": "C391.",
            "description": "Deficiencies of cell-mediated immunity",
            "attributes": null
          },
          {
            "code": "C3910",
            "description": "Cellular immunity syndr (&amp; T-lymphocyte deficiency [&amp; NOS])",
            "attributes": null
          },
          {
            "code": "C3911",
            "description": "DiGeorge syndrome",
            "attributes": null
          },
          {
            "code": "C3912",
            "description": "Wiskott-Aldrich syndrome",
            "attributes": null
          },
          {
            "code": "C3913",
            "description": "Nezelof's syndrome",
            "attributes": null
          },
          {
            "code": "C391z",
            "description": "Deficiency of cell-mediated immunity NOS",
            "attributes": null
          },
          {
            "code": "C392.",
            "description": "Combined T-cell and B-cell immunodeficiency",
            "attributes": null
          },
          {
            "code": "C3920",
            "description": "Autosomal recessive severe combined immunodeficiency",
            "attributes": null
          },
          {
            "code": "C3921",
            "description": "(Severe combined immunodefic) or (Swiss agammaglobulinaemia)",
            "attributes": null
          },
          {
            "code": "C3922",
            "description": "Thymic aplasia or dysplasia with immunodeficiency",
            "attributes": null
          },
          {
            "code": "C3923",
            "description": "Severe combined immunodefiency with reticular dysgenesis",
            "attributes": null
          },
          {
            "code": "C3924",
            "description": "Severe combined immunodef with low T- and B-cell numbers",
            "attributes": null
          },
          {
            "code": "C3925",
            "description": "Severe combined immunodef with low or normal B-cell numbers",
            "attributes": null
          },
          {
            "code": "C3928",
            "description": "Major histocompatibility complex class I deficiency",
            "attributes": null
          },
          {
            "code": "C3929",
            "description": "Major histocompatibility complex class II deficiency",
            "attributes": null
          },
          {
            "code": "C392z",
            "description": "Combined immunity deficiency NOS",
            "attributes": null
          },
          {
            "code": "C393.",
            "description": "Unspecified immunity deficiency",
            "attributes": null
          },
          {
            "code": "C396.",
            "description": "Immunodef follow hereditary defect respon Epstein-Barr vir",
            "attributes": null
          },
          {
            "code": "C3980",
            "description": "Com var immunodef with predom abn B-cell numbers and functns",
            "attributes": null
          },
          {
            "code": "C3981",
            "description": "Common var immunodef predom immunoregulatory T-cell disorder",
            "attributes": null
          },
          {
            "code": "C3982",
            "description": "Common variable immunodef wth autoantibod to B- or T-cells",
            "attributes": null
          },
          {
            "code": "C39y0",
            "description": "Lymphocyte function antigen-1 defect",
            "attributes": null
          },
          {
            "code": "Cyu00",
            "description": "[X]Other immunodeficiencies+predominantly antibody defects",
            "attributes": null
          },
          {
            "code": "Cyu01",
            "description": "[X]Other combined immunodeficiency disorders",
            "attributes": null
          },
          {
            "code": "Cyu02",
            "description": "[X]Immunodeficiency associatd+other specified major defects",
            "attributes": null
          },
          {
            "code": "Cyu03",
            "description": "[X]Immunodeficiency associated+major defect, unspecified",
            "attributes": null
          },
          {
            "code": "Cyu04",
            "description": "[X]Other common variable immunodeficiencies",
            "attributes": null
          },
          {
            "code": "Cyu05",
            "description": "[X]Other specified immunodeficiency disorders",
            "attributes": null
          },
          {
            "code": "D2016",
            "description": "Pancytopenia: [with malformation]/[with pancreatitis]/[NOS]",
            "attributes": null
          },
          {
            "code": "D4001",
            "description": "Primary splenic neutropenia",
            "attributes": null
          },
          {
            "code": "D4005",
            "description": "Congenital: [neutropenia] or [agranulocytosis NEC]",
            "attributes": null
          },
          {
            "code": "D4009",
            "description": "Cyclical neutropenia",
            "attributes": null
          },
          {
            "code": "D401.",
            "description": "(Funct dis polymorph neutroph)(Job's)(fam lipochr histiocyt)",
            "attributes": null
          },
          {
            "code": "D4010",
            "description": "Congenital dysphagocytosis",
            "attributes": null
          },
          {
            "code": "D401z",
            "description": "Polymorphonuclear neutrophil disorder NOS",
            "attributes": null
          },
          {
            "code": "D402.",
            "description": "(Anomaly: [genet leucocyt][epon vars]) or (Ched-Higash synd)",
            "attributes": null
          },
          {
            "code": "F14y0",
            "description": "Ataxia telangiectasia",
            "attributes": null
          },
          {
            "code": "M15y3",
            "description": "Complement 5 dysfunction",
            "attributes": null
          },
          {
            "code": "PK281",
            "description": "Congenital absence of thymus",
            "attributes": null
          },
          {
            "code": "X20CO",
            "description": "Pancytopenia with pancreatitis",
            "attributes": null
          },
          {
            "code": "X20Da",
            "description": "Congenital agranulocytosis NEC",
            "attributes": null
          },
          {
            "code": "X20Db",
            "description": "X-linked hypogammaglobulinaemia",
            "attributes": null
          },
          {
            "code": "X20De",
            "description": "Chronic idiopathic neutropenia",
            "attributes": null
          },
          {
            "code": "X20Df",
            "description": "Severe congenital neutropenia",
            "attributes": null
          },
          {
            "code": "X20Dk",
            "description": "Myelokathexis",
            "attributes": null
          },
          {
            "code": "X20Dl",
            "description": "Metabolic neutropenia",
            "attributes": null
          },
          {
            "code": "X20Dn",
            "description": "Autoimmune neutropenia",
            "attributes": null
          },
          {
            "code": "X20Dv",
            "description": "Chediak-Higashi syndrome",
            "attributes": null
          },
          {
            "code": "X20Dw",
            "description": "Hyperimmunoglobulin E syndrome",
            "attributes": null
          },
          {
            "code": "X20Dx",
            "description": "CR3-receptor deficiency",
            "attributes": null
          },
          {
            "code": "X20Dy",
            "description": "Specific granule deficiency",
            "attributes": null
          },
          {
            "code": "X20E0",
            "description": "Chronic granulomatous disease",
            "attributes": null
          },
          {
            "code": "X20E1",
            "description": "Myeloperoxidase deficiency",
            "attributes": null
          },
          {
            "code": "X20E4",
            "description": "Hereditary hypersegmentation",
            "attributes": null
          },
          {
            "code": "X20Ga",
            "description": "Primary immunodeficiency",
            "attributes": null
          },
          {
            "code": "X20Gb",
            "description": "Agammaglobulinaemia",
            "attributes": null
          },
          {
            "code": "X20Gc",
            "description": "X-linked agammaglobulinaemia",
            "attributes": null
          },
          {
            "code": "X20Gd",
            "description": "X-linked agammaglobulinaemia with growth hormone deficiency",
            "attributes": null
          },
          {
            "code": "X20Ge",
            "description": "Autosomal agammaglobulinaemia with absent B-cells",
            "attributes": null
          },
          {
            "code": "X20Gf",
            "description": "Selective immunoglobulin dysfunction",
            "attributes": null
          },
          {
            "code": "X20Gg",
            "description": "X-linked hyperimmunoglobulin M syndrome",
            "attributes": null
          },
          {
            "code": "X20Gh",
            "description": "Autosomal recessive hyperimmunoglobulin M syndrome",
            "attributes": null
          },
          {
            "code": "X20Gj",
            "description": "Hyperimmunoglobulin D with periodic fever",
            "attributes": null
          },
          {
            "code": "X20Gk",
            "description": "Immunoglobulin heavy chain deficiency",
            "attributes": null
          },
          {
            "code": "X20Gn",
            "description": "Selective immunoglobulin M and immunoglobulin A deficiency",
            "attributes": null
          },
          {
            "code": "X20Go",
            "description": "Immunoglobulin light chain deficiency",
            "attributes": null
          },
          {
            "code": "X20Gp",
            "description": "Kappa light chain deficiency",
            "attributes": null
          },
          {
            "code": "X20Gq",
            "description": "Lambda light chain deficiency",
            "attributes": null
          },
          {
            "code": "X20Gr",
            "description": "Immunoglobulin subclass deficiency",
            "attributes": null
          },
          {
            "code": "X20Gt",
            "description": "Immunoglobulin G2 deficiency",
            "attributes": null
          },
          {
            "code": "X20Gu",
            "description": "Combined immunoglobulin G2 and G4 deficiency",
            "attributes": null
          },
          {
            "code": "X20Gv",
            "description": "Immunoglobulin G3 deficiency",
            "attributes": null
          },
          {
            "code": "X20Gw",
            "description": "Immunoglobulin G4 deficiency",
            "attributes": null
          },
          {
            "code": "X20Gx",
            "description": "Immunoglobulin G1 deficiency",
            "attributes": null
          },
          {
            "code": "X20Gy",
            "description": "Immunoglobulin A1 deficiency",
            "attributes": null
          },
          {
            "code": "X20Gz",
            "description": "Immunoglobulin A2 deficiency",
            "attributes": null
          },
          {
            "code": "X20GZ",
            "description": "Immunodeficiency disorder",
            "attributes": null
          },
          {
            "code": "X20H0",
            "description": "Immunoglobulin-associated molecule deficiency",
            "attributes": null
          },
          {
            "code": "X20H1",
            "description": "Secretory piece deficiency",
            "attributes": null
          },
          {
            "code": "X20H2",
            "description": "Defective immunoglobulin glycosylation",
            "attributes": null
          },
          {
            "code": "X20Ha",
            "description": "Schwachman's syndrome",
            "attributes": null
          },
          {
            "code": "X20Hb",
            "description": "Defective phagocytic cell adhesion",
            "attributes": null
          },
          {
            "code": "X20Hc",
            "description": "Leucocyte adhesion deficiency - type 1",
            "attributes": null
          },
          {
            "code": "X20Hd",
            "description": "Leucocyte adhesion deficiency - type 2",
            "attributes": null
          },
          {
            "code": "X20HE",
            "description": "T-lymphocyte deficiency",
            "attributes": null
          },
          {
            "code": "X20Hf",
            "description": "Tuftsin deficiency",
            "attributes": null
          },
          {
            "code": "X20HF",
            "description": "Chronic mucocutaneous candidiasis",
            "attributes": null
          },
          {
            "code": "X20Hg",
            "description": "Defective phagocytic cell killing",
            "attributes": null
          },
          {
            "code": "X20HH",
            "description": "Combined immunodeficiency with maturation pathway defect",
            "attributes": null
          },
          {
            "code": "X20Hi",
            "description": "Leucocyte glucose-6-phosphate dehydrogenase deficiency",
            "attributes": null
          },
          {
            "code": "X20HI",
            "description": "Reticular dysgenesis",
            "attributes": null
          },
          {
            "code": "X20HJ",
            "description": "X-linked severe combined immunodeficiency",
            "attributes": null
          },
          {
            "code": "X20Hk",
            "description": "Neutrophil lactoferrin deficiency",
            "attributes": null
          },
          {
            "code": "X20HK",
            "description": "Severe combined immunodeficiency with short-limbed dwarfism",
            "attributes": null
          },
          {
            "code": "X20Hl",
            "description": "Neutrophil secondary granule deficiency",
            "attributes": null
          },
          {
            "code": "X20HL",
            "description": "Bare lymphocyte syndrome",
            "attributes": null
          },
          {
            "code": "X20Hm",
            "description": "Gluthathione synthetase deficiency",
            "attributes": null
          },
          {
            "code": "X20HM",
            "description": "Familial erythrophagocytic lymphohistiocytosis",
            "attributes": null
          },
          {
            "code": "X20Hn",
            "description": "Gluthathione peroxidase deficiency",
            "attributes": null
          },
          {
            "code": "X20HN",
            "description": "Severe comb immunodeficiency with maternofetal engraftment",
            "attributes": null
          },
          {
            "code": "X20HO",
            "description": "Warts, hypogammaglobulinaemia, infections, and myelokathexis",
            "attributes": null
          },
          {
            "code": "X20Hp",
            "description": "Combined phagocytic defect",
            "attributes": null
          },
          {
            "code": "X20Ht",
            "description": "Classical complement pathway abnormality",
            "attributes": null
          },
          {
            "code": "X20Hu",
            "description": "Complement 1q deficiency",
            "attributes": null
          },
          {
            "code": "X20HU",
            "description": "Chronic familial neutropaenia",
            "attributes": null
          },
          {
            "code": "X20Hv",
            "description": "Complement 1q beta chain deficiency",
            "attributes": null
          },
          {
            "code": "X20HV",
            "description": "Lipochrome histiocytosis - familial",
            "attributes": null
          },
          {
            "code": "X20Hw",
            "description": "Complement 1q dysfunction",
            "attributes": null
          },
          {
            "code": "X20HW",
            "description": "Defective phagocytic cell opsonisation",
            "attributes": null
          },
          {
            "code": "X20Hx",
            "description": "Complement 1r deficiency",
            "attributes": null
          },
          {
            "code": "X20HX",
            "description": "Mannan-binding protein deficiency",
            "attributes": null
          },
          {
            "code": "X20Hy",
            "description": "Complement 1s deficiency",
            "attributes": null
          },
          {
            "code": "X20HY",
            "description": "Defective phagocytic cell chemotaxis",
            "attributes": null
          },
          {
            "code": "X20Hz",
            "description": "Complement 2 deficiency",
            "attributes": null
          },
          {
            "code": "X20HZ",
            "description": "Lazy leucocyte syndrome",
            "attributes": null
          },
          {
            "code": "X20I0",
            "description": "Complement 4 deficiency",
            "attributes": null
          },
          {
            "code": "X20I1",
            "description": "Complement 4A deficiency",
            "attributes": null
          },
          {
            "code": "X20I2",
            "description": "Complement 4B deficiency",
            "attributes": null
          },
          {
            "code": "X20I3",
            "description": "Complement 3 deficiency",
            "attributes": null
          },
          {
            "code": "X20I4",
            "description": "Alternative pathway deficiency",
            "attributes": null
          },
          {
            "code": "X20I5",
            "description": "Properdin deficiency",
            "attributes": null
          },
          {
            "code": "X20I6",
            "description": "Factor B deficiency",
            "attributes": null
          },
          {
            "code": "X20I7",
            "description": "Factor D deficiency",
            "attributes": null
          },
          {
            "code": "X20I8",
            "description": "Terminal component deficiency",
            "attributes": null
          },
          {
            "code": "X20I9",
            "description": "Complement 5 deficiency",
            "attributes": null
          },
          {
            "code": "X20Ia",
            "description": "Chromosome 18 syndromes and antibody deficiency",
            "attributes": null
          },
          {
            "code": "X20Ib",
            "description": "Chromosome 22 abnormalities with hypogammaglobulinaemia",
            "attributes": null
          },
          {
            "code": "X20IB",
            "description": "Complement 6 deficiency",
            "attributes": null
          },
          {
            "code": "X20Ic",
            "description": "Monosomy 22 and absence of immunoglobulin A",
            "attributes": null
          },
          {
            "code": "X20IC",
            "description": "Complement 7 deficiency",
            "attributes": null
          },
          {
            "code": "X20Id",
            "description": "Deletion of X-chromosome and hypogammaglobulinaemia",
            "attributes": null
          },
          {
            "code": "X20ID",
            "description": "Combined complement 6 and 7 deficiencies",
            "attributes": null
          },
          {
            "code": "X20Ie",
            "description": "Microcephaly, normal intelligence and immunodeficiency",
            "attributes": null
          },
          {
            "code": "X20IE",
            "description": "Complement 8 beta chain deficiency",
            "attributes": null
          },
          {
            "code": "X20If",
            "description": "Triple X syndrome, epilepsy, and hypogammaglobulinaemia",
            "attributes": null
          },
          {
            "code": "X20IF",
            "description": "Complement 8 beta chain dysfunction",
            "attributes": null
          },
          {
            "code": "X20Ig",
            "description": "18-p syndrome with associated immunodeficiency",
            "attributes": null
          },
          {
            "code": "X20IG",
            "description": "Complement 8 alpha-gamma deficiency",
            "attributes": null
          },
          {
            "code": "X20Ih",
            "description": "Immunodeficiency with multiple organ system abnormalities",
            "attributes": null
          },
          {
            "code": "X20IH",
            "description": "Complement 9 deficiency",
            "attributes": null
          },
          {
            "code": "X20II",
            "description": "Complement regulatory factor defect",
            "attributes": null
          },
          {
            "code": "X20Ij",
            "description": "Partial albinism with immunodeficiency",
            "attributes": null
          },
          {
            "code": "X20IJ",
            "description": "Hereditary C1 esterase inhibitor defic - deficient factor",
            "attributes": null
          },
          {
            "code": "X20Ik",
            "description": "X-linked lymphoproliferative syndrome",
            "attributes": null
          },
          {
            "code": "X20IK",
            "description": "Hereditary C1 esterase inhib defic - dysfunctional factor",
            "attributes": null
          },
          {
            "code": "X20IL",
            "description": "Factor I deficiency",
            "attributes": null
          },
          {
            "code": "X20IM",
            "description": "Factor H deficiency",
            "attributes": null
          },
          {
            "code": "X20IN",
            "description": "Complement 4 binding protein deficiency",
            "attributes": null
          },
          {
            "code": "X20IO",
            "description": "Decay accelerating factor deficiency",
            "attributes": null
          },
          {
            "code": "X20IP",
            "description": "Homologous restriction factor deficiency",
            "attributes": null
          },
          {
            "code": "X20IQ",
            "description": "Complement 5a inhibitor deficiency",
            "attributes": null
          },
          {
            "code": "X20IR",
            "description": "Anaphylotoxin inactivator deficiency",
            "attributes": null
          },
          {
            "code": "X20IS",
            "description": "Complement receptor deficiency",
            "attributes": null
          },
          {
            "code": "X20IT",
            "description": "Complement receptor 1 deficiency",
            "attributes": null
          },
          {
            "code": "X20IU",
            "description": "Complement receptor 3 deficiency",
            "attributes": null
          },
          {
            "code": "X20IV",
            "description": "Immunodeficiency with major anomalies",
            "attributes": null
          },
          {
            "code": "X20IW",
            "description": "Immunodeficiency associated with chromosomal abnormality",
            "attributes": null
          },
          {
            "code": "X20IY",
            "description": "Bloom syndrome",
            "attributes": null
          },
          {
            "code": "X20IZ",
            "description": "Centromeric instability of chromosomes 1,9+16 + immunodefic",
            "attributes": null
          },
          {
            "code": "X20RX",
            "description": "Familial chronic mucocutaneous candidiasis",
            "attributes": null
          },
          {
            "code": "X40Ua",
            "description": "Adenosine deaminase deficiency",
            "attributes": null
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            "code": "X40Uc",
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            "attributes": null
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            "code": "X70R0",
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          },
          {
            "code": "X70R1",
            "description": "Chronic diffuse mucocutaneous candidiasis",
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          },
          {
            "code": "X789w",
            "description": "Immuno-osseous dysplasia",
            "attributes": null
          },
          {
            "code": "Xa9Az",
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            "attributes": null
          },
          {
            "code": "XaA0r",
            "description": "Metaphys chondrodysplas, McKusick type with assoc immunodef",
            "attributes": null
          },
          {
            "code": "XaYgn",
            "description": "Immune reconstitution syndrome",
            "attributes": null
          },
          {
            "code": "XE11u",
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            "attributes": null
          },
          {
            "code": "XE11v",
            "description": "Congenital hypogammaglobulinaemia",
            "attributes": null
          },
          {
            "code": "XE11w",
            "description": "Predominantly T-cell immuno-deficiency NOS",
            "attributes": null
          },
          {
            "code": "XE13a",
            "description": "Agammaglobulinaemia &amp;/or hypo-gammaglobulinaemia",
            "attributes": null
          },
          {
            "code": "XE14B",
            "description": "Chronic idiopathic neutropaenia",
            "attributes": null
          },
          {
            "code": "XE14F",
            "description": "Congenital neutropenia",
            "attributes": null
          },
          {
            "code": "XE14H",
            "description": "Functional disorders of polymorphonuclear neutrophils",
            "attributes": null
          }
        ]
      }
    ],
    "coding_system_release": "",
    "open_codelist_version_id": "268d3303",
    "open_codelist_version_tag": "2020-06-02",
    "status": 1,
    "doi": "https://doi.org/10.48533/6h92-th62",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 3,
      "name": "OpenCodelists Phenotype",
      "description": "OpenSafely's OpenCodelist Phenotype, visit https://www.opencodelists.org/ to learn more",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 8729,
        "version_name": "Permanent Immunosuppression",
        "version_date": "2026-01-26T23:27:12.990295Z",
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]