[ { "phenotype_id": "PH3788", "phenotype_version_id": 8939, "name": "Tricyclic and related antidepressants DM&D", "definition": "This codelist was taken from [OpenCodelists](https://www.opencodelists.org/), created by [OpenSAFELY](https://www.opensafely.org/). We recommend viewing this Phenotype on the OpenCodelist website to view the most recent version.\n\n\nThis code list contains codes from the NHS dictionary of medicines and devices (dm\\+d) that are known as Tricyclic Antidepressants. All formulations of these medicines have been included, except for those that are presented in a combined formulation with other drugs. All tricyclic antidepressants are licensed for the treatment of depression and some of them are licensed for the treatment of anxiety disorders. Certain tricyclic antidepressants are licensed for unusual psychiatric conditions e.g. clomipramine for cataplexy associated with narcolepsy. Some are also licensed for non\\-psychiatric indications, including migraine, neuropathic pain, headache.\n\n\n© University of Oxford for the Bennett Institute for Applied Data Science 2025\\. This work may be copied freely for non\\-commercial research and study.\n\n", "implementation": null, "publications": null, "validation": null, "citation_requirements": null, "created": "2026-01-26T23:34:40.892103Z", "author": "OpenSAFELY", "collections": [ { "name": "OpenCodelist", "value": 31 }, { "name": "Phenotype Library", "value": 18 } ], "tags": null, "organisation": { "id": 1, "slug": "opensafely", "name": "OpenSAFELY" }, "world_access": 1, "updated": "2026-01-26T23:34:40.885935Z", "references": [ { "url": "https://github.com/opensafely/codelist-development/issues/51", "title": "Github discussion" } ], "signed_off": [], "methodology": "All BNF codes that begin with 040301 were included (defined as Tricyclic antidepressants) except for Mianserin and Trazodone. These latter two antidepressants were excluded due to having different chemical structures and pharmacology to other tricyclics. See github discussion for more details. These BNF codes were then mapped to dm\\+d using OpenPrescribing methodology.\n\n\nFor some studies it may be necessary to include other antidepressant codelists.\n\n", "coding_system": [ { "name": "dm+d codes", "value": 23 } ], "open_codelist_id": "opensafely/tricyclic-and-related-antidepressants-dmd", "source_reference": "https://www.opencodelists.org/codelist/opensafely/tricyclic-and-related-antidepressants-dmd/1268eae1", "concept_information": [ { "concept_id": 9116, "concept_version_id": 16601, "concept_name": "opensafely/tricyclic-and-related-antidepressants-dmd/1268eae1", "coding_system": { "id": 23, "name": "dm+d codes", "description": "dm+d codes" }, "phenotype_id": "PH3788", "phenotype_version_id": 8939, "phenotype_name": "Tricyclic and related antidepressants DM&D", "code_attribute_header": [ "dmd_id", "dmd_type", "bnf_code" ], "codes": [ { "code": "101711000001102", "description": "Surmontil 50mg capsules", "attributes": { "dmd_id": "101711000001102", "dmd_type": "AMP", 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"dmd_type": "AMP", "bnf_code": "0403010B0AAAIAI" } }, { "code": "38784411000001105", "description": "Amitriptyline 50mg/5ml oral solution sugar free", "attributes": { "dmd_id": "38784411000001105", "dmd_type": "AMP", "bnf_code": "0403010B0AAAFAF" } }, { "code": "38784611000001108", "description": "Amitriptyline 10mg tablets", "attributes": { "dmd_id": "38784611000001108", "dmd_type": "AMP", "bnf_code": "0403010B0AAAGAG" } }, { "code": "38844211000001103", "description": "Clomipramine 10mg capsules", "attributes": { "dmd_id": "38844211000001103", "dmd_type": "AMP", "bnf_code": "0403010F0AAAAAA" } }, { "code": "38844411000001104", "description": "Clomipramine 25mg capsules", "attributes": { "dmd_id": "38844411000001104", "dmd_type": "AMP", "bnf_code": "0403010F0AAABAB" } }, { "code": "38844811000001102", "description": "Clomipramine 50mg capsules", "attributes": { "dmd_id": "38844811000001102", "dmd_type": "AMP", "bnf_code": "0403010F0AAACAC" } }, { "code": "38876711000001102", 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"0403010V0AAAEAE" } }, { "code": "397111000001102", "description": "Dosulepin 25mg capsules", "attributes": { "dmd_id": "397111000001102", "dmd_type": "AMP", "bnf_code": "0403010J0AAAAAA" } }, { "code": "397711000001101", "description": "Prepadine 25mg capsules", "attributes": { "dmd_id": "397711000001101", "dmd_type": "AMP", "bnf_code": "0403010J0BDABAA" } }, { "code": "398211000001107", "description": "Thaden 25mg capsules", "attributes": { "dmd_id": "398211000001107", "dmd_type": "AMP", "bnf_code": "0403010J0BFAAAA" } }, { "code": "400611000001102", "description": "Sinequan 25mg capsules", "attributes": { "dmd_id": "400611000001102", "dmd_type": "AMP", "bnf_code": "0403010L0BBABAB" } }, { "code": "404711000001100", "description": "Clomipramine 50mg capsules", "attributes": { "dmd_id": "404711000001100", "dmd_type": "AMP", "bnf_code": "0403010F0AAACAC" } }, { "code": "40611000001100", "description": "Amitriptyline 25mg tablets", "attributes": { "dmd_id": "40611000001100", "dmd_type": "AMP", "bnf_code": "0403010B0AAAHAH" } }, { "code": "4071311000001107", "description": "Lomont 70mg/5ml oral suspension", "attributes": { "dmd_id": "4071311000001107", "dmd_type": "AMP", "bnf_code": "0403010R0BCAAAL" } }, { "code": "4071511000001101", "description": "Lofepramine 70mg/5ml oral suspension sugar free", "attributes": { "dmd_id": "4071511000001101", "dmd_type": "AMP", "bnf_code": "0403010R0AAALAL" } }, { "code": "407811000001104", "description": "Dosulepin 75mg tablets", "attributes": { "dmd_id": "407811000001104", "dmd_type": "AMP", "bnf_code": "0403010J0AAAIAI" } }, { "code": "408611000001104", "description": "Dosulepin 25mg capsules", "attributes": { "dmd_id": "408611000001104", "dmd_type": "AMP", "bnf_code": "0403010J0AAAAAA" } }, { "code": "42206311000001108", "description": "VMP subsequent to 321894004", "attributes": { "dmd_id": "42206311000001108", "dmd_type": "VMP", "bnf_code": "0403010C0AAACAC" } }, { "code": "42268011000001108", "description": "VMP subsequent to 321893005", "attributes": { "dmd_id": "42268011000001108", "dmd_type": "VMP", "bnf_code": "0403010C0AAABAB" } }, { "code": "42269711000001101", "description": "VMP subsequent to 321785001", "attributes": { "dmd_id": "42269711000001101", "dmd_type": "VMP", "bnf_code": "0403010F0AAAAAA" } }, { "code": "42269811000001109", "description": "VMP subsequent to 321786000", "attributes": { "dmd_id": "42269811000001109", "dmd_type": "VMP", "bnf_code": "0403010F0AAABAB" } }, { "code": "42269911000001104", "description": "VMP subsequent to 321787009", "attributes": { "dmd_id": "42269911000001104", "dmd_type": "VMP", "bnf_code": "0403010F0AAACAC" } }, { "code": "42270611000001107", "description": "VMP subsequent to 321805008", "attributes": { "dmd_id": "42270611000001107", "dmd_type": "VMP", "bnf_code": "0403010J0AAAAAA" } }, { "code": "42270711000001103", "description": "VMP subsequent to 321806009", "attributes": { "dmd_id": "42270711000001103", "dmd_type": "VMP", "bnf_code": "0403010J0AAAIAI" } }, { "code": "42270811000001106", "description": "VMP subsequent to 321811006", "attributes": { "dmd_id": "42270811000001106", "dmd_type": "VMP", "bnf_code": "0403010L0AAAAAA" } }, { "code": "42270911000001101", "description": "VMP subsequent to 321812004", "attributes": { "dmd_id": "42270911000001101", "dmd_type": "VMP", "bnf_code": "0403010L0AAABAB" } }, { "code": "42271011000001109", "description": "VMP subsequent to 321813009", "attributes": { "dmd_id": "42271011000001109", "dmd_type": "VMP", "bnf_code": "0403010L0AAACAC" } }, { "code": "42271111000001105", "description": "VMP subsequent to 321814003", "attributes": { "dmd_id": "42271111000001105", "dmd_type": "VMP", "bnf_code": "0403010L0AAADAD" } }, { "code": "42273711000001107", "description": "VMP subsequent to 321841008", "attributes": { "dmd_id": "42273711000001107", "dmd_type": "VMP", "bnf_code": "0403010S0AAAAAA" } }, { "code": "42273811000001104", "description": "VMP subsequent to 321842001", "attributes": { "dmd_id": "42273811000001104", "dmd_type": "VMP", "bnf_code": "0403010S0AAABAB" } }, { "code": "42273911000001109", "description": "VMP subsequent to 321843006", "attributes": { "dmd_id": "42273911000001109", "dmd_type": "VMP", "bnf_code": "0403010S0AAAEAE" } }, { "code": "42274011000001107", "description": "VMP subsequent to 321844000", "attributes": { "dmd_id": "42274011000001107", "dmd_type": "VMP", "bnf_code": "0403010S0AAADAD" } }, { "code": "42280911000001107", "description": "VMP subsequent to 321887002", "attributes": { "dmd_id": "42280911000001107", "dmd_type": "VMP", "bnf_code": "0403010Y0AAABAB" } }, { "code": "42281011000001104", "description": "VMP subsequent to 321888007", "attributes": { "dmd_id": "42281011000001104", "dmd_type": "VMP", "bnf_code": "0403010Y0AAACAC" } }, { "code": "42281111000001103", "description": "VMP subsequent to 321886006", "attributes": { "dmd_id": "42281111000001103", "dmd_type": "VMP", "bnf_code": "0403010Y0AAAAAA" } }, { "code": "42291111000001104", "description": "VMP subsequent to 321745007", "attributes": { "dmd_id": "42291111000001104", "dmd_type": "VMP", "bnf_code": "0403010B0AAAGAG" } }, { "code": "42291211000001105", "description": "VMP subsequent to 321746008", "attributes": { "dmd_id": "42291211000001105", "dmd_type": "VMP", "bnf_code": "0403010B0AAAHAH" } }, { "code": "42291311000001102", "description": "VMP subsequent to 321747004", "attributes": { "dmd_id": "42291311000001102", "dmd_type": "VMP", "bnf_code": "0403010B0AAAIAI" } }, { "code": "42295311000001100", "description": "VMP subsequent to 321816001", "attributes": { "dmd_id": "42295311000001100", "dmd_type": "VMP", "bnf_code": "0403010N0AAADAD" } }, { "code": "42295411000001107", "description": "VMP subsequent to 321817005", "attributes": { "dmd_id": "42295411000001107", "dmd_type": "VMP", "bnf_code": "0403010N0AAAEAE" } }, { "code": "424211000001100", "description": "Imipramine 10mg tablets", "attributes": { "dmd_id": "424211000001100", "dmd_type": "AMP", 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