[
  {
    "phenotype_id": "PH383",
    "phenotype_version_id": 766,
    "name": "Other ADDs",
    "definition": "PURPOSE:\n\nSelf-harm is a public health problem that requires a better understanding of mortality risk. We undertook a study to examine premature mortality in a nationally representative cohort of primary care patients who had harmed themselves.\n\n\nMETHODS:\n\nDuring 2001-2013, a total of 385 general practices in England contributed data to the Clinical Practice Research Datalink with linkage to Office for National Statistics mortality records. We identified 30,017 persons aged 15 to 64 years with a recorded episode of self-harm. We estimated the relative risks of all-cause and cause-specific natural and unnatural mortality using a comparison cohort of 600,258 individuals matched on age, sex, and general practice.\n\n\nRESULTS:\n\nWe found an elevated risk of dying prematurely from any cause among the self-harm cohort, especially in the first year of follow-up (adjusted hazard ratio for that year, 3.6; 95% CI, 3.1-4.2). In particular, suicide risk was especially high during the first year (adjusted hazard ratio, 54.4; 95% CI, 34.3-86.3); although it declined sharply, it remained much higher than that in the comparison cohort. Large elevations of risk throughout the follow-up period were also observed for accidental, alcohol-related, and drug poisoning deaths. At 10 years of follow-up, cumulative incidence values were 6.5% (95% CI, 6.0%-7.1%) for allcause mortality and 1.3% (95% CI, 1.2%-1.5%) for suicide.\n\n\nCONCLUSIONS:\n\nPrimary care patients who have harmed themselves are at greatly increased risk of dying prematurely by natural and unnatural causes, and especially within a year of a first episode. These individuals visit clinicians at a relatively high frequency, which presents a clear opportunity for preventive action. Primary care patients with myriad comorbidities, including self-harming behavior, mental disorder, addictions, and physical illnesses, will require concerted, multipronged, multidisciplinary collaborative care approaches.\n\n\n\n\n\n\n\n\n",
    "implementation": "",
    "publications": [
      {
        "doi": null,
        "details": "Matthew J Carr, Darren M Ashcroft, Evangelos Kontopantelis, David While, Yvonne Awenat, Jayne Cooper, Carolyn Chew-Graham, Nav Kapur, Roger T Webb, Premature Death Among Primary Care Patients With a History of Self-Harm. Annals of Family Medicine, 15(3), 2017."
      }
    ],
    "validation": "",
    "citation_requirements": "",
    "created": "2021-10-06T16:16:47.835351Z",
    "author": "Matthew J Carr, Darren M Ashcroft, Evangelos Kontopantelis, David While, Yvonne Awenat, Jayne Cooper, Carolyn Chew-Graham, Nav Kapur, Roger T Webb",
    "collections": [
      {
        "name": "ClinicalCodes Repository",
        "value": 25
      },
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": null,
    "world_access": 1,
    "updated": "2021-10-06T16:16:47.835380Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Drug",
        "value": "3"
      }
    ],
    "ontology": null,
    "phenoflowid": "",
    "data_sources": [
      {
        "name": "CPRD GOLD",
        "value": 5,
        "uid": "a29feafa-7bdd-44e9-b977-c9d26425e67f",
        "url": "https://healthdatagateway.org/en/dataset/694",
        "datasource_id": 694
      }
    ],
    "coding_system": [
      {
        "name": "Multilex codes",
        "value": 16
      }
    ],
    "event_date_range": "01/01/2001 - 31/12/2013",
    "concept_information": [
      {
        "concept_id": 1713,
        "concept_version_id": 4564,
        "concept_name": "Other ADDs - Primary Care",
        "coding_system": {
          "id": 16,
          "name": "Multilex codes",
          "description": "Multilex codes"
        },
        "phenotype_id": "PH383",
        "phenotype_version_id": 766,
        "phenotype_name": "Other ADDs",
        "code_attribute_header": [
          "Entity type",
          "Coding System (Multilex)",
          "Category"
        ],
        "codes": [
          {
            "code": "10967020",
            "description": "Duloxetine 60mg gastro-resistant capsules (Sigma Pharmaceuticals Plc)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "21206020",
            "description": "Mirtazapine 15mg/ml oral solution sugar free (A A H Pharmaceuticals Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "35355020",
            "description": "Venlafaxine 150mg/5ml oral solution",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "35357020",
            "description": "Venlafaxine 37.5mg/5ml oral solution",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "35359020",
            "description": "Venlafaxine 75mg/5ml oral solution",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "3818020",
            "description": "Fluanxol 1mg tablets (Sigma Pharmaceuticals Plc)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "38595020",
            "description": "Mirtazapine 15mg tablets (Medreich Plc)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "3942020",
            "description": "Venlafaxine 37.5mg tablets (Ranbaxy (UK) Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "3965020",
            "description": "Venlablue XL 75mg capsules (Bluefish Pharmaceuticals AB)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "3966020",
            "description": "Alventa XL 75mg capsules (Consilient Health Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "3970020",
            "description": "Efexor XL 150mg capsules (Waymade Healthcare Plc)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "3976020",
            "description": "Venlablue XL 150mg capsules (Bluefish Pharmaceuticals AB)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "3977020",
            "description": "Alventa XL 150mg capsules (Consilient Health Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "41252020",
            "description": "Mirtazapine 15mg orodispersible tablets sugar free",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "41253020",
            "description": "Mirtazapine 15mg orodispersible tablets sugar free (Sandoz Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "41254020",
            "description": "Mirtazapine 45mg orodispersible tablets sugar free",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "48376020",
            "description": "Efexor 37.5mg tablets (Wyeth Pharmaceuticals)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "48377020",
            "description": "Efexor 75mg tablets (Wyeth Pharmaceuticals)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "49502020",
            "description": "Fluanxol 500microgram tablets (Lundbeck Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "49503020",
            "description": "Fluanxol 1mg tablets (Lundbeck Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "50286020",
            "description": "Marplan 10mg Tablet (Cambridge Laboratories Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "50620020",
            "description": "Nardil 15mg tablets (Archimedes Pharma UK Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "50868020",
            "description": "Optimax 500mg tablets (Merck Serono Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "50957020",
            "description": "Pacitron 500mg Tablet (Rorer Pharmaceuticals Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "51010020",
            "description": "Parnate 10mg Tablet (Goldshield Pharmaceuticals Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "51013020",
            "description": "Parstelin Tablet (GlaxoSmithKline Consumer Healthcare)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "54686020",
            "description": "Venlafaxine 37.5mg tablets",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "54687020",
            "description": "Venlafaxine 75mg tablets",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "54978020",
            "description": "Optimax wv Tablet (E. Merck)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "59180020",
            "description": "Isocarboxazid 10mg Tablet (Cambridge Laboratories Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "62025020",
            "description": "Flupentixol 500microgram tablets",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "62026020",
            "description": "Flupentixol 1mg tablets",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "63638020",
            "description": "Isocarboxazid 10mg tablets",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "63795020",
            "description": "Moclobemide 150mg tablets (Teva UK Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "65266020",
            "description": "Tranylcypromine 10mg tablets (AMCo)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "65635020",
            "description": "Phenelzine 15mg tablets",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "67145020",
            "description": "Tranylcypromine 10mg tablets",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "67148020",
            "description": "Tranylcypromine with trifluoperazine Tablet",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "67310020",
            "description": "Tryptophan 500mg tablets",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "67314020",
            "description": "Tryptophan with ascorbic acid and pyridoxine powder",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "68128020",
            "description": "Mirtazapine 15mg/ml oral solution sugar free (Rosemont Pharmaceuticals Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "68213020",
            "description": "Mirtazapine 30mg tablets (Actavis UK Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "68484020",
            "description": "Mirtazapine 30mg tablets (A A H Pharmaceuticals Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "69003020",
            "description": "Trifluoperazine with tranylcypromine 1mg + 10mg Tablet",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "69827020",
            "description": "Mirtazapine 15mg tablets (A A H Pharmaceuticals Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "69832020",
            "description": "Mirtazapine 45mg tablets (A A H Pharmaceuticals Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "70353020",
            "description": "Mirtazapine 15mg tablets (Arrow Generics Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "71074020",
            "description": "Mirtazapine 15mg tablets (Genus Pharmaceuticals Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "71994020",
            "description": "Manerix 150mg tablets (Meda Pharmaceuticals Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "71995020",
            "description": "Manerix 300mg tablets (Meda Pharmaceuticals Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "72031020",
            "description": "Moclobemide 150mg tablets",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "72032020",
            "description": "Moclobemide 300mg tablets",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "74026020",
            "description": "Mirtazapine 15mg orodispersible tablets (Teva UK Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "74033020",
            "description": "Mirtazapine 45mg orodispersible tablets (Teva UK Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "74665020",
            "description": "Mirtazapine 30mg orodispersible tablets (Actavis UK Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "74668020",
            "description": "Mirtazapine 45mg orodispersible tablets (Actavis UK Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "74684020",
            "description": "Mirtazapine 15mg orodispersible tablets (Focus Pharmaceuticals Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "74689020",
            "description": "Mirtazapine 45mg orodispersible tablets (Focus Pharmaceuticals Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "74702020",
            "description": "Mirtazapine 15mg orodispersible tablets (A A H Pharmaceuticals Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "74705020",
            "description": "Mirtazapine 30mg orodispersible tablets (A A H Pharmaceuticals Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "74708020",
            "description": "Mirtazapine 45mg orodispersible tablets (A A H Pharmaceuticals Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "74967020",
            "description": "Mirtazapine 15mg orodispersible tablets (Genus Pharmaceuticals Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "74977020",
            "description": "Mirtazapine 45mg orodispersible tablets (Genus Pharmaceuticals Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "75309020",
            "description": "Mirtazapine 15mg tablets (Teva UK Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "76425020",
            "description": "Mirtazapine 15mg tablets (Actavis UK Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "76512020",
            "description": "Mirtazapine 15mg orodispersible tablets (Aurobindo Pharma Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "78577020",
            "description": "Mirtazapine 30mg orodispersible tablets (Almus Pharmaceuticals Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "84955020",
            "description": "Reboxetine 4mg tablets",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "84961020",
            "description": "Edronax 4mg tablets (Pfizer Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "85108020",
            "description": "Venlafaxine 75mg modified-release capsules",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "85109020",
            "description": "Venlafaxine 150mg modified-release capsules",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "85163020",
            "description": "Efexor XL 75mg capsules (Pfizer Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "85164020",
            "description": "Efexor XL 150mg capsules (Pfizer Ltd)",
            "attributes": {
              "Entity type": "res41: Other ADDs",
              "Coding System (Multilex)": "Multilex",
              "Category": "drug"
            }
          },
          {
            "code": "85247020",
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