[
  {
    "phenotype_id": "PH3964",
    "phenotype_version_id": 9161,
    "name": "has_sickle_cell_immuno_def",
    "definition": "This codelist was taken from [OpenCodelists](https://www.opencodelists.org/), created by [OpenSAFELY](https://www.opensafely.org/). We recommend viewing this Phenotype on the OpenCodelist website to view the most recent version.\n\n\nSNOMED codelist for the `has_sickle_cell_immuno_def` group in the QCovid® to develop the\n COVID\\-19 Population Risk Assessment.\n\n\n© University of Oxford for the Bennett Institute for Applied Data Science 2025\\. This work may be copied freely for non\\-commercial research and study.\n\n",
    "implementation": null,
    "publications": null,
    "validation": null,
    "citation_requirements": null,
    "created": "2026-01-26T23:41:39.643421Z",
    "author": "QCovid",
    "collections": [
      {
        "name": "OpenCodelist",
        "value": 31
      },
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": {
      "id": 1,
      "slug": "opensafely",
      "name": "OpenSAFELY"
    },
    "world_access": 1,
    "updated": "2026-01-26T23:41:39.635445Z",
    "references": [
      {
        "url": "https://digital.nhs.uk/coronavirus/risk-assessment/population/code-list-used-for-population-risk-assessment",
        "title": "NHSD QCovid codelists"
      }
    ],
    "signed_off": [],
    "methodology": "",
    "coding_system": [
      {
        "name": "SNOMED  CT codes",
        "value": 9
      }
    ],
    "open_codelist_id": "qcovid/has_sickle_cell_immuno_def",
    "source_reference": "https://www.opencodelists.org/codelist/qcovid/has_sickle_cell_immuno_def/1c049d7d",
    "concept_information": [
      {
        "concept_id": 9338,
        "concept_version_id": 16823,
        "concept_name": "qcovid/has_sickle_cell_immuno_def/1c049d7d",
        "coding_system": {
          "id": 9,
          "name": "SNOMED  CT codes",
          "description": "SNOMED CT codes"
        },
        "phenotype_id": "PH3964",
        "phenotype_version_id": 9161,
        "phenotype_name": "has_sickle_cell_immuno_def",
        "code_attribute_header": [],
        "codes": [
          {
            "code": "119249001",
            "description": "Agammaglobulinemia (finding)",
            "attributes": null
          },
          {
            "code": "119250001",
            "description": "Hypogammaglobulinemia (finding)",
            "attributes": null
          },
          {
            "code": "127040003",
            "description": "Sickle cell-hemoglobin SS disease (disorder)",
            "attributes": null
          },
          {
            "code": "127041004",
            "description": "Sickle cell-beta-thalassemia (disorder)",
            "attributes": null
          },
          {
            "code": "165816005",
            "description": "Human immunodeficiency virus positive (finding)",
            "attributes": null
          },
          {
            "code": "190979003",
            "description": "Selective immunoglobulin A deficiency (disorder)",
            "attributes": null
          },
          {
            "code": "190980000",
            "description": "Selective immunoglobulin M deficiency (disorder)",
            "attributes": null
          },
          {
            "code": "190981001",
            "description": "Selective immunoglobulin G deficiency (disorder)",
            "attributes": null
          },
          {
            "code": "190986006",
            "description": "Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia (finding)",
            "attributes": null
          },
          {
            "code": "191008001",
            "description": "Immunodeficiency following hereditary defective response to Epstein-Barr virus (disorder)",
            "attributes": null
          },
          {
            "code": "191011000",
            "description": "Common variable immunodeficiency with predominant abnormalities of B-cell numbers and functions (disorder)",
            "attributes": null
          },
          {
            "code": "191012007",
            "description": "Common variable immunodeficiency with predominant immunoregulatory T-cell disorders (disorder)",
            "attributes": null
          },
          {
            "code": "191018006",
            "description": "Lymphocyte function antigen-1 defect (disorder)",
            "attributes": null
          },
          {
            "code": "193370005",
            "description": "Proliferative retinopathy due to sickle cell disease (disorder)",
            "attributes": null
          },
          {
            "code": "23238000",
            "description": "Common variable agammaglobulinemia (disorder)",
            "attributes": null
          },
          {
            "code": "234434003",
            "description": "Alders syndrome (disorder)",
            "attributes": null
          },
          {
            "code": "234532001",
            "description": "Immunodeficiency disorder (disorder)",
            "attributes": null
          },
          {
            "code": "234549008",
            "description": "Immunoglobulin G4 deficiency (disorder)",
            "attributes": null
          },
          {
            "code": "234631003",
            "description": "Immunodeficiency with major anomalies (disorder)",
            "attributes": null
          },
          {
            "code": "24743004",
            "description": "Complement deficiency disease (disorder)",
            "attributes": null
          },
          {
            "code": "25472008",
            "description": "Sickle cell-hemoglobin D disease (disorder)",
            "attributes": null
          },
          {
            "code": "267460002",
            "description": "Congenital hypogammaglobulinemia (finding)",
            "attributes": null
          },
          {
            "code": "31323000",
            "description": "Severe combined immunodeficiency disease (disorder)",
            "attributes": null
          },
          {
            "code": "35434009",
            "description": "Sickle cell-hemoglobin C disease (disorder)",
            "attributes": null
          },
          {
            "code": "36070007",
            "description": "Wiskott-Aldrich syndrome (disorder)",
            "attributes": null
          },
          {
            "code": "398055000",
            "description": "T-lymphocyte deficiency (finding)",
            "attributes": null
          },
          {
            "code": "398271008",
            "description": "Predominantly T-cell defect (finding)",
            "attributes": null
          },
          {
            "code": "414029004",
            "description": "Disorder of immune function (disorder)",
            "attributes": null
          },
          {
            "code": "417425009",
            "description": "Hemoglobin SS disease with crisis (disorder)",
            "attributes": null
          },
          {
            "code": "426202004",
            "description": "Immune reconstitution syndrome (disorder)",
            "attributes": null
          },
          {
            "code": "4434006",
            "description": "Bloom syndrome (disorder)",
            "attributes": null
          },
          {
            "code": "47986005",
            "description": "Genetic anomaly of leukocyte (disorder)",
            "attributes": null
          },
          {
            "code": "50926003",
            "description": "Job's syndrome (disorder)",
            "attributes": null
          },
          {
            "code": "65880007",
            "description": "X-linked agammaglobulinemia (disorder)",
            "attributes": null
          },
          {
            "code": "703538003",
            "description": "Mannose-binding lectin deficiency (disorder)",
            "attributes": null
          },
          {
            "code": "88714009",
            "description": "Transient hypogammaglobulinemia of infancy (disorder)",
            "attributes": null
          },
          {
            "code": "9893005",
            "description": "Immunodeficiency with thymoma (disorder)",
            "attributes": null
          }
        ]
      }
    ],
    "coding_system_release": "",
    "open_codelist_version_id": "1c049d7d",
    "open_codelist_version_tag": "",
    "status": 1,
    "doi": "https://doi.org/10.48533/tnns-wk35",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 3,
      "name": "OpenCodelists Phenotype",
      "description": "OpenSafely's OpenCodelist Phenotype, visit https://www.opencodelists.org/ to learn more",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 9161,
        "version_name": "has_sickle_cell_immuno_def",
        "version_date": "2026-01-26T23:41:39.653026Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]