[
  {
    "phenotype_id": "PH4002",
    "phenotype_version_id": 9199,
    "name": "cancer immunosuppression",
    "definition": "This codelist was taken from [OpenCodelists](https://www.opencodelists.org/), created by [OpenSAFELY](https://www.opensafely.org/). We recommend viewing this Phenotype on the OpenCodelist website to view the most recent version.\n\n\nCodelist for cancer immunosuppression which may be associated with repeat (prophylactic) antibiotic prescribing in primary care. Antibiotic prophylaxis is recommended for patients with or at risk of serious neutropenia (e.g. following hematopoietic stem\\-cell transplantation or treatment with myeloablative conditioning regimens \\[total body irradiation or chemotherapy])\n\n\n© University of Oxford for the Bennett Institute for Applied Data Science 2025\\. This work may be copied freely for non\\-commercial research and study.\n\n",
    "implementation": null,
    "publications": null,
    "validation": null,
    "citation_requirements": null,
    "created": "2026-01-26T23:42:38.392381Z",
    "author": "UKHSA",
    "collections": [
      {
        "name": "OpenCodelist",
        "value": 31
      },
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": {
      "id": 1,
      "slug": "opensafely",
      "name": "OpenSAFELY"
    },
    "world_access": 1,
    "updated": "2026-01-26T23:42:38.388005Z",
    "references": [
      {
        "url": "https://emedicine.medscape.com/article/2500036-overview?reg=1",
        "title": "Antimicrobial Agents in Neutropenic Cancer Patients"
      }
    ],
    "signed_off": [],
    "methodology": "Searched for myeloablative, stem cell transplant, and neutropenia. Restricted neutropenia to chemotherapy\\-induced.\n\n",
    "coding_system": [
      {
        "name": "SNOMED  CT codes",
        "value": 9
      }
    ],
    "open_codelist_id": "ukhsa/cancer-immunosuppression",
    "source_reference": "https://www.opencodelists.org/codelist/ukhsa/cancer-immunosuppression/398dc482",
    "concept_information": [
      {
        "concept_id": 9376,
        "concept_version_id": 16861,
        "concept_name": "ukhsa/cancer-immunosuppression/398dc482",
        "coding_system": {
          "id": 9,
          "name": "SNOMED  CT codes",
          "description": "SNOMED CT codes"
        },
        "phenotype_id": "PH4002",
        "phenotype_version_id": 9199,
        "phenotype_name": "cancer immunosuppression",
        "code_attribute_header": [],
        "codes": [
          {
            "code": "153351000119102",
            "description": "History of peripheral stem cell transplant",
            "attributes": null
          },
          {
            "code": "19944001",
            "description": "Autologous bone marrow transplant without purging",
            "attributes": null
          },
          {
            "code": "228311000000103",
            "description": "Allograft of bone marrow from haploidentical donor",
            "attributes": null
          },
          {
            "code": "234331007",
            "description": "Syngeneic bone marrow transplant",
            "attributes": null
          },
          {
            "code": "234332000",
            "description": "T-cell depleted allogeneic bone marrow graft",
            "attributes": null
          },
          {
            "code": "234333005",
            "description": "Imperfect T-cell depleted allogeneic bone marrow graft",
            "attributes": null
          },
          {
            "code": "234334004",
            "description": "Allogeneic related bone marrow transplant",
            "attributes": null
          },
          {
            "code": "234335003",
            "description": "Allogeneic unrelated bone marrow transplant",
            "attributes": null
          },
          {
            "code": "234336002",
            "description": "Hemopoietic stem cell transplant",
            "attributes": null
          },
          {
            "code": "23719005",
            "description": "Transplantation of bone marrow",
            "attributes": null
          },
          {
            "code": "278256002",
            "description": "Cord cell transfusion",
            "attributes": null
          },
          {
            "code": "278257006",
            "description": "Peripheral blood stem cell graft",
            "attributes": null
          },
          {
            "code": "284671000000102",
            "description": "Autologous peripheral blood stem cell transplant",
            "attributes": null
          },
          {
            "code": "284681000000100",
            "description": "Syngeneic peripheral blood stem cell transplant",
            "attributes": null
          },
          {
            "code": "284691000000103",
            "description": "Allogeneic peripheral blood stem cell transplant",
            "attributes": null
          },
          {
            "code": "291281000000102",
            "description": "Autologous peripheral blood stem cell transplant",
            "attributes": null
          },
          {
            "code": "291291000000100",
            "description": "Syngeneic peripheral blood stem cell transplant",
            "attributes": null
          },
          {
            "code": "291301000000101",
            "description": "Allogeneic peripheral blood stem cell transplant",
            "attributes": null
          },
          {
            "code": "378841000000102",
            "description": "Allograft of bone marrow from unmatched unrelated donor",
            "attributes": null
          },
          {
            "code": "425229001",
            "description": "Chemotherapy-induced neutropenia",
            "attributes": null
          },
          {
            "code": "425563003",
            "description": "Grafting of cord blood to bone marrow",
            "attributes": null
          },
          {
            "code": "425843001",
            "description": "Allogeneic peripheral blood stem cell transplant",
            "attributes": null
          },
          {
            "code": "425983008",
            "description": "Autologous peripheral blood stem cell transplant",
            "attributes": null
          },
          {
            "code": "426425001",
            "description": "Allograft of bone marrow from sibling donor",
            "attributes": null
          },
          {
            "code": "427423003",
            "description": "Allograft of bone marrow from matched unrelated donor",
            "attributes": null
          },
          {
            "code": "427615008",
            "description": "Allograft of cord blood to bone marrow",
            "attributes": null
          },
          {
            "code": "442557006",
            "description": "Grafting of bone marrow using allograft from unmatched unrelated donor",
            "attributes": null
          },
          {
            "code": "445757003",
            "description": "Allogeneic bone marrow transplantation without purging",
            "attributes": null
          },
          {
            "code": "446253009",
            "description": "Allogeneic bone marrow transplantation with purging",
            "attributes": null
          },
          {
            "code": "46280001",
            "description": "Autologous bone marrow transplant with purging",
            "attributes": null
          },
          {
            "code": "58390007",
            "description": "Allogeneic bone marrow transplantation",
            "attributes": null
          },
          {
            "code": "58776007",
            "description": "Autologous bone marrow transplant",
            "attributes": null
          },
          {
            "code": "698075004",
            "description": "Syngeneic peripheral blood stem cell transplantation",
            "attributes": null
          },
          {
            "code": "709115004",
            "description": "Transplantation of autologous hematopoietic stem cell",
            "attributes": null
          },
          {
            "code": "711429001",
            "description": "Transplantation of autologous progenitor cell",
            "attributes": null
          },
          {
            "code": "767658000",
            "description": "Neutropenia due to and following chemotherapy",
            "attributes": null
          },
          {
            "code": "870253002",
            "description": "Myeloablative conditioning regimen",
            "attributes": null
          }
        ]
      }
    ],
    "coding_system_release": "",
    "open_codelist_version_id": "398dc482",
    "open_codelist_version_tag": "",
    "status": 1,
    "doi": "https://doi.org/10.48533/90jc-tg31",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 3,
      "name": "OpenCodelists Phenotype",
      "description": "OpenSafely's OpenCodelist Phenotype, visit https://www.opencodelists.org/ to learn more",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 9199,
        "version_name": "cancer immunosuppression",
        "version_date": "2026-01-26T23:42:38.398655Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]