[ { "phenotype_id": "PH403", "phenotype_version_id": 806, "name": "Angiotensin-Iireceptorantagonists", "definition": "Patient level data were extracted from the General Practice Research Database (GPRD), which contains anonymised, patient based data on morbidity, prescribing, treatment, and referral collected from over 500 general practices, covering about 7% of the UK population (4.4 million patients).14 Data are in Read code format—a hierarchical system used to code clinical data. Additional data on prescriptions and test results are available as free-text entries. We selected a sample of 148 practices that provided data to the GPRD continuously between January 2000 and December 2007, structured to include a range of list (patient panel) sizes. Selected practices were nationally representative in terms of patient sex and age distribution and area socioeconomic deprivation but had a relatively large average list size, reflecting a bias towards larger practices in the GPRD. Overall, the selected practices performed marginally better than national practices on the clinical indicators in the Quality and Outcomes Framework. A random selection of 4500 patients registered for at least one day between 1 January 2000 and 31 December 2007 was drawn from each practice. For practices with fewer than 4501 patients, all patients were selected. The final sample consisted of 653 500 patients. Patients with relevant conditions were identified from their diagnostic Read codes. Patients for whom targets were met were identified from the relevant Read codes and free-text terms.\n\n\n\n\n\n\n\n\n", "implementation": "", "publications": [ { "doi": null, "details": "Tim Doran, Evangelos Kontopantelis, Jose M Valderas, Stephen Campbell, Martin Roland, Chris Salisbury, David Reeves, Effect of financial incentives on incentivised and non-incentivised clinical activities: longitudinal analysis of data from the UK Quality and Outcomes Framework. BMJ, 342:d3590, 2011." } ], "validation": "", "citation_requirements": "", "created": "2021-10-06T16:17:52.837657Z", "author": "Tim Doran, Evangelos Kontopantelis, Jose M Valderas, Stephen Campbell, Martin Roland, Chris Salisbury, David Reeves", "collections": [ { "name": "ClinicalCodes Repository", "value": 25 }, { "name": "Phenotype Library", "value": 18 } ], "tags": null, "organisation": null, "world_access": 1, "updated": "2021-10-06T16:17:52.837686Z", "sex": [ { "name": "Both", "value": "3" } ], "type": [ { "name": "Drug", "value": "3" } ], "ontology": null, "phenoflowid": "", "data_sources": [ { "name": "CPRD GOLD", "value": 5, "uid": "a29feafa-7bdd-44e9-b977-c9d26425e67f", "url": "https://healthdatagateway.org/en/dataset/694", "datasource_id": 694 } ], "coding_system": [ { "name": "GPRD product codes", "value": 14 } ], "event_date_range": "01/01/2000 - 31/12/2007", "concept_information": [ { "concept_id": 1736, "concept_version_id": 4610, "concept_name": "Angiotensin-Iireceptorantagonists - Primary Care", "coding_system": { "id": 14, "name": "GPRD product codes", "description": "GPRD product codes" }, "phenotype_id": "PH403", "phenotype_version_id": 806, "phenotype_name": "Angiotensin-Iireceptorantagonists", "code_attribute_header": [ "Entity type", "Category", "Coding System (GPRD_product_code)" ], "codes": [ { "code": "10485001", "description": "VALSARTAN caps 40mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "10485002", "description": "VALSARTAN caps 80mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "10485003", "description": "VALSARTAN caps 160mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "10486001", "description": "DIOVAN caps 40mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "10486002", "description": "DIOVAN caps 80mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "10486003", "description": "DIOVAN caps 160mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "10707001", "description": "COAPROVEL tabs 150mg + 12.5mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "10707002", "description": "COAPROVEL tabs 300mg + 12.5mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "10716001", "description": "EPROSARTAN tabs 300mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "10716002", "description": "EPROSARTAN tabs 400mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "10716003", "description": "EPROSARTAN tabs 600mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "10717001", "description": "TEVETEN tabs 300mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "10717002", "description": "TEVETEN tabs 400mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "10717003", "description": "TEVETEN tabs 600mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "11492001", "description": "IRBESARTAN tabs 75mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "11492002", "description": "IRBESARTAN tabs 150mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "11492003", "description": "IRBESARTAN tabs 300mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } 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"description": "VALSARTAN tabs 40mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "12847001", "description": "DIOVAN tabs 40mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "12971001", "description": "CANDESARTAN tabs 32mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "12972001", "description": "AMIAS tabs 32mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "13477001", "description": "LOSARTAN + HYDROCHLOROTHIAZIDE tabs 100mg + 25mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", 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"code": "14583001", "description": "VALSARTAN (IPU) tabs 80mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "14585001", "description": "VALSARTAN (IPU) tabs 160mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "14780001", "description": "IRBESARTAN + HYDROCHLOROTHIAZIDE tabs 300mg + 25mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "14781001", "description": "COAPROVEL tabs 300mg + 25mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "2350001", "description": "OLMETEC tabs 40mg", "attributes": { "Entity type": 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"GPRD_product_code" } }, { "code": "7009003", "description": "TELMISARTAN tabs 20mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "7482001", "description": "COZAAR tabs 50mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "7482002", "description": "COZAAR tabs 25mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "7483001", "description": "LOSARTAN tabs 50mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "7483002", "description": "LOSARTAN tabs 25mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", 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"attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "9922001", "description": "COZAAR-COMP tabs 50mg + 12.5mg", "attributes": { "Entity type": "Angiotensin-II receptor antagonists", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } } ] } ], "status": 2, "doi": "https://doi.org/10.48533/dbsp-9e59", "is_deleted": null, "publish_status": 2, "owner": "ieuan.scanlon", "template": { "id": 1, "name": "Clinical-Coded Phenotype", "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.", "version_id": 1 }, "versions": [ { "version_id": 806, "version_name": "Angiotensin-Iireceptorantagonists", "version_date": "2021-10-06T16:17:52.859880Z", "is_published": true, "is_latest": true } ] } ]