[ { "phenotype_id": "PH4094", "phenotype_version_id": 9312, "name": "Allergic and chronic rhinitis", "definition": "Allergic rhinitis is inflammation of the inside of the nose caused by an allergen, such as pollen, dust, mould or flakes of skin from certain animals.\n\nUKB baseline self reported fields.\n", "implementation": "The earliest record across all sources is obtained.\n", "publications": [ { "doi": "https://doi.org/10.1038/s41598-025-05838-9", "details": "Torralbo, Ana and Davitte, Jonathan M. and Croteau-Chonka, Damien C. and Ytsma, Cai R. and Tomlinson, Christopher and Fitzpatrick, Natalie and Chung, Sheng-Chia and Fatemifar, Ghazaleh and Cortes, Adrian S. and Richardson, Tom G. and Barclay, Matthew and Carrasco Zanini Sanchez, Julia and Finan, Chris and Hemingway, Harry and Hingorani, Aroon D. and Kuan Po Ai, Valerie and Langenberg, Claudia and Lyratzopoulos, Georgios and Lumbers, Tom and Pietzner, Maik and Shah, Anoop Dinesh and Thygesen, Johan Hilge and Zelenka, Natalie and Whittaker, John C. and Ehm, Margaret G. and Denaxas, Spiros, A Computational Framework for Defining and Validating Reproducible Phenotyping Algorithms of 313 Diseases in the UK Biobank.", "primary": true } ], "validation": "Phenotypes underwent a multi\\-layered validation approach that included a) evaluating data source concordance, b) age\\-sex incidence and baseline prevalence patterns, c) an external comparison to a representative and unselected UK EHR dataset, d) modifiable risk factor associations, and e) genetic correlations with external genome\\-wide association studies (GWAS). Results showed consistent disease distributions by age and sex, high ranked correlation with general population prevalence estimates, confirmed risk factor associations, and significant genetic correlations with external GWAS.\n", "citation_requirements": null, "created": "2026-06-08T20:05:29.280575Z", "author": "Torralbo, A; Davitte, J M; Croteau-Chonka, D C; Ytsma, C; Tomlinson, C; Fitzpatrick, N K; Chung, S C; Fatemifar, G; Cortes, A S; Richardson, T G; Barclay, M; Carrasco Zanini, J; Finan, C; Hemingway, H; Hingorani, A; Kuan, V; Langenberg, C; Lyratzopoulos, G; Lumbers, R T; Pietzner, M; Shah, A D; Thygesen, J H; Zelenka, N; Whittaker, J C; Ehm, M G; Denaxas, S", "collections": [ { "name": "Phenotype Library", "value": 18 }, { "name": "UK Biobank", "value": 32 } ], "tags": null, "organisation": null, "world_access": 1, "updated": "2026-06-08T20:05:29.275067Z", "sex": [ { "name": "Both", "value": "3" } ], "type": [ { "name": "Disease or syndrome", "value": "2" } ], "trials": null, "ontology": [ { "name": "Allergic rhinitis (disorder)", "value": 261755 } ], "phenoflowid": null, "data_sources": [ { "name": "UK Biobank", "value": 13, "uid": "6a9f93ad-2434-41d9-93bf-6e9d2eee04e5", "url": "https://healthdatagateway.org/en/dataset/700", "datasource_id": 700 }, { "name": "Patient Episode Dataset for Wales (PEDW)", "value": 40, "uid": "4c33a5d2-164c-41d7-9797-dc2b008cc852", "url": "https://healthdatagateway.org/en/dataset/318", "datasource_id": 318 }, { "name": "Scottish Cancer Registry (SMR06)", "value": 417, "uid": "ad36dc03-1856-44de-99b0-1af6f312d86b", "url": "https://healthdatagateway.org/en/dataset/79", "datasource_id": 79 }, { "name": "Cancer Registration Data", "value": 788, "uid": "6904a2ff-ab44-4dd6-b9ec-25d3cad29e43", "url": "https://healthdatagateway.org/en/dataset/880", "datasource_id": 880 } ], "endorsements": null, "project_name": null, "coding_system": [ { "name": "ICD10 codes", "value": 4 }, { "name": "UKBioBank codes", "value": 12 }, { "name": "Non-standard codes", "value": 13 }, { "name": "Read codes v3", "value": 6 } ], "corresp_author": "Ana Torralbo", "event_date_range": null, "concept_information": [ { "concept_id": 9568, "concept_version_id": 17053, "concept_name": "Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor", "coding_system": { "id": 13, "name": "Non-standard codes", "description": "Non-standard codes" }, "phenotype_id": "PH4094", "phenotype_version_id": 9312, "phenotype_name": "Allergic and chronic rhinitis", "code_attribute_header": [ "type" ], "codes": [ { "code": "9", "description": "Hayfever, allergic rhinitis or eczema", "attributes": { "type": "any" } } ] }, { "concept_id": 9569, "concept_version_id": 17054, "concept_name": "Non-cancer illness code, self-reported", "coding_system": { "id": 12, "name": "UKBioBank codes", "description": "UKBioBank codes" }, "phenotype_id": "PH4094", "phenotype_version_id": 9312, "phenotype_name": "Allergic and chronic rhinitis", "code_attribute_header": [ "type" ], "codes": [ { "code": "1387", "description": "hayfever/allergic rhinitis", "attributes": { "type": "any" } }, { "code": "1668", "description": "allergy to house dust mite", "attributes": { "type": "any" } } ] }, { "concept_id": 9570, "concept_version_id": 17055, "concept_name": "Diagnoses - main ICD10", "coding_system": { "id": 4, "name": "ICD10 codes", "description": "ICD10 Codes" }, "phenotype_id": "PH4094", "phenotype_version_id": 9312, "phenotype_name": "Allergic and chronic rhinitis", "code_attribute_header": [ "type" ], "codes": [ { "code": "J30.1", "description": "Allergic rhinitis due to pollen", "attributes": { "type": "any" } }, { "code": "J30.2", "description": "Other seasonal allergic rhinitis", "attributes": { "type": "any" } }, { "code": "J30.3", "description": "Other allergic rhinitis", "attributes": { "type": "any" } }, { "code": "J30.4", "description": "Allergic rhinitis, unspecified", "attributes": { "type": "any" } }, { "code": "J31.0", "description": "Chronic rhinitis", "attributes": { "type": "any" } } ] }, { "concept_id": 9571, "concept_version_id": 17056, "concept_name": "Diagnoses - secondary ICD10", "coding_system": { "id": 4, "name": "ICD10 codes", "description": "ICD10 Codes" }, "phenotype_id": "PH4094", "phenotype_version_id": 9312, "phenotype_name": "Allergic and chronic rhinitis", "code_attribute_header": [ "type" ], "codes": [ { "code": "J30.1", "description": "Allergic rhinitis due to pollen", "attributes": { "type": "any" } }, { "code": "J30.2", "description": "Other seasonal allergic rhinitis", "attributes": { "type": "any" } }, { "code": "J30.3", "description": "Other allergic rhinitis", "attributes": { "type": "any" } }, { "code": "J30.4", "description": "Allergic rhinitis, unspecified", "attributes": { "type": "any" } }, { "code": "J31.0", "description": "Chronic rhinitis", "attributes": { "type": "any" } } ] }, { "concept_id": 9572, "concept_version_id": 17057, "concept_name": "Underlying (primary) cause of death: ICD10", "coding_system": { "id": 4, "name": "ICD10 codes", "description": "ICD10 Codes" }, "phenotype_id": "PH4094", "phenotype_version_id": 9312, "phenotype_name": "Allergic and chronic rhinitis", "code_attribute_header": [ "type" ], "codes": [ { "code": "J30.1", "description": "Allergic rhinitis due to pollen", "attributes": { "type": "any" } }, { "code": "J30.2", "description": "Other seasonal allergic rhinitis", "attributes": { "type": "any" } }, { "code": "J30.3", "description": "Other allergic rhinitis", "attributes": { "type": "any" } }, { "code": "J30.4", "description": "Allergic rhinitis, unspecified", "attributes": { "type": "any" } }, { "code": "J31.0", "description": "Chronic rhinitis", "attributes": { "type": "any" } } ] }, { "concept_id": 9573, "concept_version_id": 17058, "concept_name": "Contributory (secondary) causes of death: ICD10", "coding_system": { "id": 4, "name": "ICD10 codes", "description": "ICD10 Codes" }, "phenotype_id": "PH4094", "phenotype_version_id": 9312, "phenotype_name": "Allergic and chronic rhinitis", "code_attribute_header": [ "type" ], "codes": [ { "code": "J30.1", "description": "Allergic rhinitis due to pollen", "attributes": { "type": "any" } }, { "code": "J30.2", "description": "Other seasonal allergic rhinitis", "attributes": { "type": "any" } }, { "code": "J30.3", "description": "Other allergic rhinitis", "attributes": { "type": "any" } }, { "code": "J30.4", "description": "Allergic rhinitis, unspecified", "attributes": { "type": "any" } }, { "code": "J31.0", "description": "Chronic rhinitis", "attributes": { "type": "any" } } ] }, { "concept_id": 9574, "concept_version_id": 17059, "concept_name": "GP clinical event records", "coding_system": { "id": 6, "name": "Read codes v3", "description": "Read codes v3" }, "phenotype_id": "PH4094", "phenotype_version_id": 9312, "phenotype_name": "Allergic and chronic rhinitis", "code_attribute_header": [ "type" ], "codes": [ { "code": "14B1.00", "description": "H/O: hay fever", "attributes": { "type": "prevalent" } }, { "code": "H120.00", "description": "Chronic rhinitis", "attributes": { "type": "any" } }, { "code": "H120000", "description": "Chronic simple rhinitis", "attributes": { "type": "any" } }, { "code": "H120100", "description": "Chronic catarrhal rhinitis", "attributes": { "type": "any" } }, { "code": "H120200", "description": "Chronic hypertrophic rhinitis", "attributes": { "type": "any" } }, { "code": "H120300", "description": "Chronic atrophic rhinitis", "attributes": { "type": "any" } }, { "code": "H120400", "description": "Chronic infective rhinitis", "attributes": { "type": "any" } }, { "code": "H120500", "description": "Chronic ulcerative rhinitis", "attributes": { "type": "any" } }, { "code": "H120600", "description": "Chronic membranous rhinitis", "attributes": { "type": "any" } }, { "code": "H120700", "description": "Chronic fibrinous rhinitis", "attributes": { "type": "any" } }, { "code": "H120z00", "description": "Chronic rhinitis NOS", "attributes": { "type": "any" } }, { "code": "H13..11", "description": "Chronic rhinosinusitis", "attributes": { "type": "any" } }, { "code": "H17..00", "description": "Allergic rhinitis", "attributes": { "type": "any" } }, { "code": "H170.00", "description": "Allergic rhinitis due to pollens", "attributes": { "type": "any" } }, { "code": "H170.11", "description": "Hay fever - pollens", "attributes": { "type": "any" } }, { "code": "H170.12", "description": "Pollinosis", "attributes": { "type": "any" } }, { "code": "H171.00", "description": "Allergic rhinitis due to other allergens", "attributes": { "type": "any" } }, { "code": "H171000", "description": "Allergy to animal", "attributes": { "type": "any" } }, { "code": "H17..11", "description": "Perennial rhinitis", "attributes": { "type": "any" } }, { "code": "H171100", "description": "Dog allergy", "attributes": { "type": "any" } }, { "code": "H171.11", "description": "Cat allergy", "attributes": { "type": "any" } }, { "code": "H171.12", "description": "Dander (animal) allergy", "attributes": { "type": "any" } }, { "code": "H171.13", "description": "Feather allergy", "attributes": { "type": "any" } }, { "code": "H171.14", "description": "Hay fever - other allergen", "attributes": { "type": "any" } }, { "code": "H171.15", "description": "House dust allergy", "attributes": { "type": "any" } }, { "code": "H171.16", "description": "House dust mite allergy", "attributes": { "type": "any" } }, { "code": "H17..12", "description": "Allergic rhinosinusitis", "attributes": { "type": "any" } }, { "code": "H172.00", "description": "Allergic rhinitis due to unspecified allergen", "attributes": { "type": "any" } }, { "code": "H172.11", "description": "Hay fever - unspecified allergen", "attributes": { "type": "any" } }, { "code": "H17z.00", "description": "Allergic rhinitis NOS", "attributes": { "type": "any" } }, { "code": "H18..00", "description": "Vasomotor rhinitis", "attributes": { "type": "any" } }, { "code": "H330011", "description": "Hay fever with asthma", "attributes": { "type": "any" } }, { "code": "H330.13", "description": "Hay fever with asthma", "attributes": { "type": "any" } }, { "code": "Hyu2000", "description": "[X]Other seasonal allergic rhinitis", "attributes": { "type": "any" } }, { "code": "Hyu2100", "description": "[X]Other allergic rhinitis", "attributes": { "type": "any" } }, { "code": "XaIpW", "description": "Allergy to animal", "attributes": { "type": "any" } }, { "code": "XE0Xx", "description": "Chronic rhinitis", "attributes": { "type": "any" } }, { "code": "XE0Xy", "description": "Chronic catarrhal rhinitis", "attributes": { "type": "any" } }, { "code": "XE0Y5", "description": "Allergic rhinitis", "attributes": { "type": "any" } }, { "code": "XE0Y6", "description": "Allergic rhinitis due to other allergens", "attributes": { "type": "any" } }, { "code": "XE0Y7", "description": "Allergic rhinitis due to unspecified allergen", "attributes": { "type": "any" } }, { "code": "XE0YR", "description": "Extrinsic asthma without status asthmaticus", "attributes": { "type": "any" } }, { "code": "XE2QI", "description": "Allergic rhinitis due to pollens", "attributes": { "type": "any" } } ] }, { "concept_id": 9575, "concept_version_id": 17060, "concept_name": "Doctor diagnosed hayfever or allergic rhinitis", "coding_system": { "id": 13, "name": "Non-standard codes", "description": "Non-standard codes" }, "phenotype_id": "PH4094", "phenotype_version_id": 9312, "phenotype_name": "Allergic and chronic rhinitis", "code_attribute_header": [ "type" ], "codes": [ { "code": "1", "description": "yes", "attributes": { "type": "any" } } ] }, { "concept_id": 9576, "concept_version_id": 17061, "concept_name": "Recent medication for hayfever or allergic rhinitis", "coding_system": { "id": 13, "name": "Non-standard codes", "description": "Non-standard codes" }, "phenotype_id": "PH4094", "phenotype_version_id": 9312, "phenotype_name": "Allergic and chronic rhinitis", "code_attribute_header": [ "type" ], "codes": [ { "code": "1", "description": "yes", "attributes": { "type": "any" } } ] } ], "status": 1, "doi": "https://doi.org/10.48533/n0ck-mp76", "is_deleted": false, "publish_status": 2, "owner": "ieuan.scanlon", "template": { "id": 2, "name": "BHF Data Science Centre Phenotype", "description": "BHF Data Science Centre Phenotype definitions that describe a list of clinical codes, algorithms using clinical codes, or set of clinical trials. Visit the BHF Data Science Centre website to learn more: https://bhfdatasciencecentre.org", "version_id": 1 }, "versions": [ { "version_id": 9312, "version_name": "Allergic and chronic rhinitis", "version_date": "2026-06-08T20:05:29.291729Z", "is_published": true, "is_latest": true } ] } ]