[
  {
    "phenotype_id": "PH4102",
    "phenotype_version_id": 9320,
    "name": "Anorectal prolapse",
    "definition": "Protrusion of the rectal mucous membrane through the anus. There are various degrees: incomplete with no displacement of the anal sphincter muscle; complete with displacement of the anal sphincter muscle; complete with no displacement of the anal sphincter muscle but with herniation of the bowel; and internal complete with rectosigmoid or upper rectum intussusception into the lower rectum.\n\nUKB baseline self reported fields.\n",
    "implementation": "The earliest record across all sources is obtained.\n",
    "publications": [
      {
        "doi": "https://doi.org/10.1038/s41598-025-05838-9",
        "details": "Torralbo, Ana and Davitte, Jonathan M. and Croteau-Chonka, Damien C. and Ytsma, Cai R. and Tomlinson, Christopher and Fitzpatrick, Natalie and Chung, Sheng-Chia and Fatemifar, Ghazaleh and Cortes, Adrian S. and Richardson, Tom G. and Barclay, Matthew and Carrasco Zanini Sanchez, Julia and Finan, Chris and Hemingway, Harry and Hingorani, Aroon D. and Kuan Po Ai, Valerie and Langenberg, Claudia and Lyratzopoulos, Georgios and Lumbers, Tom and Pietzner, Maik and Shah, Anoop Dinesh and Thygesen, Johan Hilge and Zelenka, Natalie and Whittaker, John C. and Ehm, Margaret G. and Denaxas, Spiros, A Computational Framework for Defining and Validating Reproducible Phenotyping Algorithms of 313 Diseases in the UK Biobank.",
        "primary": true
      }
    ],
    "validation": "Phenotypes underwent a multi\\-layered validation approach that included a) evaluating data source concordance, b) age\\-sex incidence and baseline prevalence patterns, c) an external comparison to a representative and unselected UK EHR dataset, d) modifiable risk factor associations, and e) genetic correlations with external genome\\-wide association studies (GWAS). Results showed consistent disease distributions by age and sex, high ranked correlation with general population prevalence estimates, confirmed risk factor associations, and significant genetic correlations with external GWAS.\n",
    "citation_requirements": null,
    "created": "2026-06-08T20:05:51.589020Z",
    "author": "Torralbo, A; Davitte, J M; Croteau-Chonka, D C; Ytsma, C; Tomlinson, C; Fitzpatrick, N K; Chung, S C; Fatemifar, G; Cortes, A S; Richardson, T G; Barclay, M; Carrasco Zanini, J; Finan, C; Hemingway, H; Hingorani, A; Kuan, V; Langenberg, C; Lyratzopoulos, G; Lumbers, R T; Pietzner, M; Shah, A D; Thygesen, J H; Zelenka, N; Whittaker, J C; Ehm, M G; Denaxas, S",
    "collections": [
      {
        "name": "Phenotype Library",
        "value": 18
      },
      {
        "name": "UK Biobank",
        "value": 32
      }
    ],
    "tags": null,
    "organisation": null,
    "world_access": 1,
    "updated": "2026-06-08T20:05:51.580401Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Disease or syndrome",
        "value": "2"
      }
    ],
    "trials": null,
    "ontology": [
      {
        "name": "Rectal prolapse (disorder)",
        "value": 87691
      }
    ],
    "phenoflowid": null,
    "data_sources": [
      {
        "name": "UK Biobank",
        "value": 13,
        "uid": "6a9f93ad-2434-41d9-93bf-6e9d2eee04e5",
        "url": "https://healthdatagateway.org/en/dataset/700",
        "datasource_id": 700
      },
      {
        "name": "Patient Episode Dataset for Wales (PEDW)",
        "value": 40,
        "uid": "4c33a5d2-164c-41d7-9797-dc2b008cc852",
        "url": "https://healthdatagateway.org/en/dataset/318",
        "datasource_id": 318
      },
      {
        "name": "Scottish Cancer Registry (SMR06)",
        "value": 417,
        "uid": "ad36dc03-1856-44de-99b0-1af6f312d86b",
        "url": "https://healthdatagateway.org/en/dataset/79",
        "datasource_id": 79
      },
      {
        "name": "Cancer Registration Data",
        "value": 788,
        "uid": "6904a2ff-ab44-4dd6-b9ec-25d3cad29e43",
        "url": "https://healthdatagateway.org/en/dataset/880",
        "datasource_id": 880
      }
    ],
    "endorsements": null,
    "project_name": null,
    "coding_system": [
      {
        "name": "UKBioBank codes",
        "value": 12
      },
      {
        "name": "ICD10 codes",
        "value": 4
      },
      {
        "name": "Read codes v3",
        "value": 6
      },
      {
        "name": "OPCS4 codes",
        "value": 7
      }
    ],
    "corresp_author": "Ana Torralbo",
    "event_date_range": null,
    "concept_information": [
      {
        "concept_id": 9618,
        "concept_version_id": 17103,
        "concept_name": "Non-cancer illness code, self-reported",
        "coding_system": {
          "id": 12,
          "name": "UKBioBank codes",
          "description": "UKBioBank codes"
        },
        "phenotype_id": "PH4102",
        "phenotype_version_id": 9320,
        "phenotype_name": "Anorectal prolapse",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "1603",
            "description": "rectal prolapse",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9619,
        "concept_version_id": 17104,
        "concept_name": "Diagnoses - main ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4102",
        "phenotype_version_id": 9320,
        "phenotype_name": "Anorectal prolapse",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "K62.2",
            "description": "Anal prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "K62.3",
            "description": "Rectal prolapse",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9620,
        "concept_version_id": 17105,
        "concept_name": "Diagnoses - secondary ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4102",
        "phenotype_version_id": 9320,
        "phenotype_name": "Anorectal prolapse",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "K62.2",
            "description": "Anal prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "K62.3",
            "description": "Rectal prolapse",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9621,
        "concept_version_id": 17106,
        "concept_name": "Operative procedures - main OPCS4",
        "coding_system": {
          "id": 7,
          "name": "OPCS4 codes",
          "description": "OPCS4 codes"
        },
        "phenotype_id": "PH4102",
        "phenotype_version_id": 9320,
        "phenotype_name": "Anorectal prolapse",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "H36",
            "description": "Other abdominal operations for prolapse of rectum",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H36.1",
            "description": "Abdominal repair of levator ani muscles",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H36.8",
            "description": "Other specified other abdominal operations for prolapse of rectum",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H36.9",
            "description": "Unspecified other abdominal operations for prolapse of rectum",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H42",
            "description": "Perineal operations for prolapse of rectum",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H42.1",
            "description": "Insertion of encircling suture around perianal sphincter",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H42.2",
            "description": "Perineal plication of levator ani muscles and anal sphincters",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H42.3",
            "description": "Insertion of supralevator sling",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H42.4",
            "description": "Removal of encircling suture from around perianal sphincter",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H42.5",
            "description": "Excision of mucosal prolapse of rectum NEC",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H42.6",
            "description": "Perineal repair of prolapse of rectum NEC",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H42.8",
            "description": "Other specified perineal operations for prolapse of rectum",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H42.9",
            "description": "Unspecified perineal operations for prolapse of rectum",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H44.2",
            "description": "Manual reduction of prolapse of rectum",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9622,
        "concept_version_id": 17107,
        "concept_name": "Operative procedures - secondary OPCS4",
        "coding_system": {
          "id": 7,
          "name": "OPCS4 codes",
          "description": "OPCS4 codes"
        },
        "phenotype_id": "PH4102",
        "phenotype_version_id": 9320,
        "phenotype_name": "Anorectal prolapse",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "H36",
            "description": "H36",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H36.1",
            "description": "H36.1",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H36.8",
            "description": "H36.8",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H36.9",
            "description": "H36.9",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H42",
            "description": "H42",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H42.1",
            "description": "H42.1",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H42.2",
            "description": "H42.2",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H42.3",
            "description": "H42.3",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H42.4",
            "description": "H42.4",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H42.5",
            "description": "H42.5",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H42.6",
            "description": "H42.6",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H42.8",
            "description": "H42.8",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H42.9",
            "description": "H42.9",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H44.2",
            "description": "H44.2",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9623,
        "concept_version_id": 17108,
        "concept_name": "Underlying (primary) cause of death: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4102",
        "phenotype_version_id": 9320,
        "phenotype_name": "Anorectal prolapse",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "K62.2",
            "description": "Anal prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "K62.3",
            "description": "Rectal prolapse",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9624,
        "concept_version_id": 17109,
        "concept_name": "Contributory (secondary) causes of death: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4102",
        "phenotype_version_id": 9320,
        "phenotype_name": "Anorectal prolapse",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "K62.2",
            "description": "Anal prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "K62.3",
            "description": "Rectal prolapse",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9625,
        "concept_version_id": 17110,
        "concept_name": "GP clinical event records",
        "coding_system": {
          "id": 6,
          "name": "Read codes v3",
          "description": "Read codes v3"
        },
        "phenotype_id": "PH4102",
        "phenotype_version_id": 9320,
        "phenotype_name": "Anorectal prolapse",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "7720.00",
            "description": "Partial excision of rectum and sigmoid colon for prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7720y00",
            "description": "Partial excision of rectum and sigmoid colon for prolapse OS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7720z00",
            "description": "Partial excision of rectum & sigmoid colon for prolapse NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7723.00",
            "description": "Fixation of rectum for prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7723.11",
            "description": "Proctopexy for prolapse of rectum",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7723.12",
            "description": "Rectopexy for prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7723400.0",
            "description": "Proctopexy for prolapse of rectum",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7723411.0",
            "description": "Erickman repair of prolapse of rectum",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7723500.0",
            "description": "Insertion of sponge for rectal prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7723511.0",
            "description": "Insertion of Wells sponge for rectal prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7723y00",
            "description": "Other specified fixation of rectum for prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7723z00",
            "description": "Fixation of rectum for prolapse NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7724.00",
            "description": "Other abdominal operations for rectal prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7724011.0",
            "description": "Graham repair for rectal prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7724012.0",
            "description": "Roscoe repair for rectal prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7724y00",
            "description": "Other abdominal operation for rectal prolapse OS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7724y11",
            "description": "Delorme repair of rectum for prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7724z00",
            "description": "Other abdominal operation for rectal prolapse NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7726400.0",
            "description": "Reduction of prolapsed rectum NEC",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7727.00",
            "description": "Perineal operations for rectal prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7727011.0",
            "description": "Thiersch wiring for prolapse of rectum",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7727400.0",
            "description": "Excision of mucosal prolapse of rectum NEC",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7727500.0",
            "description": "Perineal repair of rectal prolapse NEC",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7727y00",
            "description": "Other specified perineal operation for rectal prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7727z00",
            "description": "Perineal operation for rectal prolapse NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7728400.0",
            "description": "Manual reduction of rectal prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "J571.00",
            "description": "Rectal prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "J571000",
            "description": "Partial rectal prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "J571100",
            "description": "Complete rectal prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "J571.11",
            "description": "Procidentia - anus and/or rectum",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "J571.12",
            "description": "Proctoptosis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "J571200",
            "description": "Anal prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "J571z00",
            "description": "Rectal prolapse NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "J579.00",
            "description": "Rectal mucosa prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XaMym",
            "description": "Rectal mucosa prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XaQbP",
            "description": "Anal prolapse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XE0Dh",
            "description": "Proctopexy for prolapse of rectum",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XE0Dj",
            "description": "Abdominal repair of levator ani muscles",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XE0Dk",
            "description": "Other specified other abdominal operation for rectal prolapse",
            "attributes": {
              "type": "any"
            }
          }
        ]
      }
    ],
    "status": 1,
    "doi": "https://doi.org/10.48533/q9wa-hb47",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 2,
      "name": "BHF Data Science Centre Phenotype",
      "description": "BHF Data Science Centre Phenotype definitions that describe a list of clinical codes, algorithms using clinical codes, or set of clinical trials. Visit the BHF Data Science Centre website to learn more: https://bhfdatasciencecentre.org",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 9320,
        "version_name": "Anorectal prolapse",
        "version_date": "2026-06-08T20:05:51.599980Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]