[
  {
    "phenotype_id": "PH4103",
    "phenotype_version_id": 9321,
    "name": "Anterior and Intermediate Uveitis",
    "definition": "Inflammation of the iris and anterior chamber of the eye.\n\nUKB baseline self reported fields.\n",
    "implementation": "The earliest record across all sources is obtained.\n",
    "publications": [
      {
        "doi": "https://doi.org/10.1038/s41598-025-05838-9",
        "details": "Torralbo, Ana and Davitte, Jonathan M. and Croteau-Chonka, Damien C. and Ytsma, Cai R. and Tomlinson, Christopher and Fitzpatrick, Natalie and Chung, Sheng-Chia and Fatemifar, Ghazaleh and Cortes, Adrian S. and Richardson, Tom G. and Barclay, Matthew and Carrasco Zanini Sanchez, Julia and Finan, Chris and Hemingway, Harry and Hingorani, Aroon D. and Kuan Po Ai, Valerie and Langenberg, Claudia and Lyratzopoulos, Georgios and Lumbers, Tom and Pietzner, Maik and Shah, Anoop Dinesh and Thygesen, Johan Hilge and Zelenka, Natalie and Whittaker, John C. and Ehm, Margaret G. and Denaxas, Spiros, A Computational Framework for Defining and Validating Reproducible Phenotyping Algorithms of 313 Diseases in the UK Biobank.",
        "primary": true
      }
    ],
    "validation": "Phenotypes underwent a multi\\-layered validation approach that included a) evaluating data source concordance, b) age\\-sex incidence and baseline prevalence patterns, c) an external comparison to a representative and unselected UK EHR dataset, d) modifiable risk factor associations, and e) genetic correlations with external genome\\-wide association studies (GWAS). Results showed consistent disease distributions by age and sex, high ranked correlation with general population prevalence estimates, confirmed risk factor associations, and significant genetic correlations with external GWAS.\n",
    "citation_requirements": null,
    "created": "2026-06-08T20:05:54.754605Z",
    "author": "Torralbo, A; Davitte, J M; Croteau-Chonka, D C; Ytsma, C; Tomlinson, C; Fitzpatrick, N K; Chung, S C; Fatemifar, G; Cortes, A S; Richardson, T G; Barclay, M; Carrasco Zanini, J; Finan, C; Hemingway, H; Hingorani, A; Kuan, V; Langenberg, C; Lyratzopoulos, G; Lumbers, R T; Pietzner, M; Shah, A D; Thygesen, J H; Zelenka, N; Whittaker, J C; Ehm, M G; Denaxas, S",
    "collections": [
      {
        "name": "Phenotype Library",
        "value": 18
      },
      {
        "name": "UK Biobank",
        "value": 32
      }
    ],
    "tags": null,
    "organisation": null,
    "world_access": 1,
    "updated": "2026-06-08T20:05:54.749359Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Disease or syndrome",
        "value": "2"
      }
    ],
    "trials": null,
    "ontology": [
      {
        "name": "Anterior uveitis (disorder)",
        "value": 738256
      }
    ],
    "phenoflowid": null,
    "data_sources": [
      {
        "name": "UK Biobank",
        "value": 13,
        "uid": "6a9f93ad-2434-41d9-93bf-6e9d2eee04e5",
        "url": "https://healthdatagateway.org/en/dataset/700",
        "datasource_id": 700
      },
      {
        "name": "Patient Episode Dataset for Wales (PEDW)",
        "value": 40,
        "uid": "4c33a5d2-164c-41d7-9797-dc2b008cc852",
        "url": "https://healthdatagateway.org/en/dataset/318",
        "datasource_id": 318
      },
      {
        "name": "Scottish Cancer Registry (SMR06)",
        "value": 417,
        "uid": "ad36dc03-1856-44de-99b0-1af6f312d86b",
        "url": "https://healthdatagateway.org/en/dataset/79",
        "datasource_id": 79
      },
      {
        "name": "Cancer Registration Data",
        "value": 788,
        "uid": "6904a2ff-ab44-4dd6-b9ec-25d3cad29e43",
        "url": "https://healthdatagateway.org/en/dataset/880",
        "datasource_id": 880
      }
    ],
    "endorsements": null,
    "project_name": null,
    "coding_system": [
      {
        "name": "UKBioBank codes",
        "value": 12
      },
      {
        "name": "ICD10 codes",
        "value": 4
      },
      {
        "name": "Read codes v3",
        "value": 6
      }
    ],
    "corresp_author": "Ana Torralbo",
    "event_date_range": null,
    "concept_information": [
      {
        "concept_id": 9626,
        "concept_version_id": 17111,
        "concept_name": "Non-cancer illness code, self-reported",
        "coding_system": {
          "id": 12,
          "name": "UKBioBank codes",
          "description": "UKBioBank codes"
        },
        "phenotype_id": "PH4103",
        "phenotype_version_id": 9321,
        "phenotype_name": "Anterior and Intermediate Uveitis",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "1530",
            "description": "iritis",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9627,
        "concept_version_id": 17112,
        "concept_name": "Diagnoses - main ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4103",
        "phenotype_version_id": 9321,
        "phenotype_name": "Anterior and Intermediate Uveitis",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "H20.0",
            "description": "Acute and subacute iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H20.1",
            "description": "Chronic iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H20.2",
            "description": "Lens-induced iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H20.8",
            "description": "Other iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H20.9",
            "description": "Iridocyclitis, unspecified",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H22.0",
            "description": "Iridocyclitis in infectious and parasitic diseases classified elsewhere",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H22.1",
            "description": "Iridocyclitis in other diseases classified elsewhere",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H30.2",
            "description": "Posterior cyclitis",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9628,
        "concept_version_id": 17113,
        "concept_name": "Diagnoses - secondary ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4103",
        "phenotype_version_id": 9321,
        "phenotype_name": "Anterior and Intermediate Uveitis",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "H20.0",
            "description": "Acute and subacute iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H20.1",
            "description": "Chronic iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H20.2",
            "description": "Lens-induced iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H20.8",
            "description": "Other iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H20.9",
            "description": "Iridocyclitis, unspecified",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H22.0",
            "description": "Iridocyclitis in infectious and parasitic diseases classified elsewhere",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H22.1",
            "description": "Iridocyclitis in other diseases classified elsewhere",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H30.2",
            "description": "Posterior cyclitis",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9629,
        "concept_version_id": 17114,
        "concept_name": "Underlying (primary) cause of death: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4103",
        "phenotype_version_id": 9321,
        "phenotype_name": "Anterior and Intermediate Uveitis",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "H20.0",
            "description": "Acute and subacute iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H20.1",
            "description": "Chronic iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H20.2",
            "description": "Lens-induced iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H20.8",
            "description": "Other iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H20.9",
            "description": "Iridocyclitis, unspecified",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H22.0",
            "description": "Iridocyclitis in infectious and parasitic diseases classified elsewhere",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H22.1",
            "description": "Iridocyclitis in other diseases classified elsewhere",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H30.2",
            "description": "Posterior cyclitis",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9630,
        "concept_version_id": 17115,
        "concept_name": "Contributory (secondary) causes of death: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4103",
        "phenotype_version_id": 9321,
        "phenotype_name": "Anterior and Intermediate Uveitis",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "H20.0",
            "description": "Acute and subacute iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H20.1",
            "description": "Chronic iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H20.2",
            "description": "Lens-induced iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H20.8",
            "description": "Other iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H20.9",
            "description": "Iridocyclitis, unspecified",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H22.0",
            "description": "Iridocyclitis in infectious and parasitic diseases classified elsewhere",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H22.1",
            "description": "Iridocyclitis in other diseases classified elsewhere",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H30.2",
            "description": "Posterior cyclitis",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9631,
        "concept_version_id": 17116,
        "concept_name": "GP clinical event records",
        "coding_system": {
          "id": 6,
          "name": "Read codes v3",
          "description": "Read codes v3"
        },
        "phenotype_id": "PH4103",
        "phenotype_version_id": 9321,
        "phenotype_name": "Anterior and Intermediate Uveitis",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "1486.00",
            "description": "H/O: iritis",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "A173300",
            "description": "Tuberculous chronic iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "A532200",
            "description": "Herpes zoster iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "A544400",
            "description": "Herpes simplex iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "A984100",
            "description": "Gonococcal iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "C34y300",
            "description": "Gouty iritis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F432300",
            "description": "Posterior cyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F432311",
            "description": "Pars planitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F440.00",
            "description": "Acute and subacute iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F440000",
            "description": "Unspecified acute iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F440100",
            "description": "Unspecified subacute iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F440.11",
            "description": "Iritis - acute",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F440200",
            "description": "Primary iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F440300",
            "description": "Recurrent iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F440400",
            "description": "Secondary infected iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F440500",
            "description": "Secondary noninfected iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F440600",
            "description": "Hypopyon",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F440700",
            "description": "Diabetic iritis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F440z00",
            "description": "Acute or subacute iritis NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F441.00",
            "description": "Chronic iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F441000",
            "description": "Unspecified chronic iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F441100",
            "description": "Chronic iridocyclitis due to disease EC",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F441.11",
            "description": "Chronic iritis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F44..12",
            "description": "Iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F441200",
            "description": "Chronic anterior uveitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F441z00",
            "description": "Chronic iridocyclitis NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F442.00",
            "description": "Certain types of iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F442000",
            "description": "Fuchs' heterochromic cyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F442100",
            "description": "Glaucomatocyclitic crises",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F442200",
            "description": "Lens-induced iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F442z00",
            "description": "Certain types of cyclitis NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F443.00",
            "description": "Unspecified iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F443000",
            "description": "Anterior uveitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F443100",
            "description": "Iritis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F443.11",
            "description": "Uveitis NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "X00be",
            "description": "Anterior uveitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XaBM3",
            "description": "Chronic anterior uveitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XaF43",
            "description": "Posterior cyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XE167",
            "description": "Acute and subacute iridocyclitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XE16A",
            "description": "Unspecified iridocyclitis",
            "attributes": {
              "type": "any"
            }
          }
        ]
      }
    ],
    "status": 1,
    "doi": "https://doi.org/10.48533/66gz-yz73",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 2,
      "name": "BHF Data Science Centre Phenotype",
      "description": "BHF Data Science Centre Phenotype definitions that describe a list of clinical codes, algorithms using clinical codes, or set of clinical trials. Visit the BHF Data Science Centre website to learn more: https://bhfdatasciencecentre.org",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 9321,
        "version_name": "Anterior and Intermediate Uveitis",
        "version_date": "2026-06-08T20:05:54.766363Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]