[ { "phenotype_id": "PH4108", "phenotype_version_id": 9326, "name": "Aspiration pneumonitis", "definition": "A type of lung inflammation resulting from the aspiration of food, liquid, or gastric contents into the upper RESPIRATORY TRACT.\n\nUKB baseline self reported fields.\n", "implementation": "The earliest record across all sources is obtained.\n", "publications": [ { "doi": "https://doi.org/10.1038/s41598-025-05838-9", "details": "Torralbo, Ana and Davitte, Jonathan M. and Croteau-Chonka, Damien C. and Ytsma, Cai R. and Tomlinson, Christopher and Fitzpatrick, Natalie and Chung, Sheng-Chia and Fatemifar, Ghazaleh and Cortes, Adrian S. and Richardson, Tom G. and Barclay, Matthew and Carrasco Zanini Sanchez, Julia and Finan, Chris and Hemingway, Harry and Hingorani, Aroon D. and Kuan Po Ai, Valerie and Langenberg, Claudia and Lyratzopoulos, Georgios and Lumbers, Tom and Pietzner, Maik and Shah, Anoop Dinesh and Thygesen, Johan Hilge and Zelenka, Natalie and Whittaker, John C. and Ehm, Margaret G. and Denaxas, Spiros, A Computational Framework for Defining and Validating Reproducible Phenotyping Algorithms of 313 Diseases in the UK Biobank.", "primary": true } ], "validation": "Phenotypes underwent a multi\\-layered validation approach that included a) evaluating data source concordance, b) age\\-sex incidence and baseline prevalence patterns, c) an external comparison to a representative and unselected UK EHR dataset, d) modifiable risk factor associations, and e) genetic correlations with external genome\\-wide association studies (GWAS). Results showed consistent disease distributions by age and sex, high ranked correlation with general population prevalence estimates, confirmed risk factor associations, and significant genetic correlations with external GWAS.\n", "citation_requirements": null, "created": "2026-06-08T20:06:09.978891Z", "author": "Torralbo, A; Davitte, J M; Croteau-Chonka, D C; Ytsma, C; Tomlinson, C; Fitzpatrick, N K; Chung, S C; Fatemifar, G; Cortes, A S; Richardson, T G; Barclay, M; Carrasco Zanini, J; Finan, C; Hemingway, H; Hingorani, A; Kuan, V; Langenberg, C; Lyratzopoulos, G; Lumbers, R T; Pietzner, M; Shah, A D; Thygesen, J H; Zelenka, N; Whittaker, J C; Ehm, M G; Denaxas, S", "collections": [ { "name": "Phenotype Library", "value": 18 }, { "name": "UK Biobank", "value": 32 } ], "tags": null, "organisation": null, "world_access": 1, "updated": "2026-06-08T20:06:09.972540Z", "sex": [ { "name": "Both", "value": "3" } ], "type": [ { "name": "Disease or syndrome", "value": "2" } ], "trials": null, "ontology": [ { "name": "Aspiration pneumonitis (disorder)", "value": 437485 } ], "phenoflowid": null, "data_sources": [ { "name": "UK Biobank", "value": 13, "uid": "6a9f93ad-2434-41d9-93bf-6e9d2eee04e5", "url": "https://healthdatagateway.org/en/dataset/700", "datasource_id": 700 }, { "name": "Patient Episode Dataset for Wales (PEDW)", "value": 40, "uid": "4c33a5d2-164c-41d7-9797-dc2b008cc852", "url": "https://healthdatagateway.org/en/dataset/318", "datasource_id": 318 }, { "name": "Scottish Cancer Registry (SMR06)", "value": 417, "uid": "ad36dc03-1856-44de-99b0-1af6f312d86b", "url": "https://healthdatagateway.org/en/dataset/79", "datasource_id": 79 }, { "name": "Cancer Registration Data", "value": 788, "uid": "6904a2ff-ab44-4dd6-b9ec-25d3cad29e43", "url": "https://healthdatagateway.org/en/dataset/880", "datasource_id": 880 } ], "endorsements": null, "project_name": null, "coding_system": [ { "name": "ICD10 codes", "value": 4 }, { "name": "Read codes v3", "value": 6 } ], "corresp_author": "Ana Torralbo", "event_date_range": null, "concept_information": [ { "concept_id": 9661, "concept_version_id": 17146, "concept_name": "Diagnoses - main ICD10", "coding_system": { "id": 4, "name": "ICD10 codes", "description": "ICD10 Codes" }, "phenotype_id": "PH4108", "phenotype_version_id": 9326, "phenotype_name": "Aspiration pneumonitis", "code_attribute_header": [ "type" ], "codes": [ { "code": "J69.0", "description": "Pneumonitis due to food and vomit", "attributes": { "type": "any" } }, { "code": "J69.1", "description": "Pneumonitis due to oils and essences", "attributes": { "type": "any" } }, { "code": "J69.8", "description": "Pneumonitis due to other solids and liquids", "attributes": { "type": "any" } } ] }, { "concept_id": 9662, "concept_version_id": 17147, "concept_name": "Diagnoses - secondary ICD10", "coding_system": { "id": 4, "name": "ICD10 codes", "description": "ICD10 Codes" }, "phenotype_id": "PH4108", "phenotype_version_id": 9326, "phenotype_name": "Aspiration pneumonitis", "code_attribute_header": [ "type" ], "codes": [ { "code": "J69.0", "description": "Pneumonitis due to food and vomit", "attributes": { "type": "any" } }, { "code": "J69.1", "description": "Pneumonitis due to oils and essences", "attributes": { "type": "any" } }, { "code": "J69.8", "description": "Pneumonitis due to other solids and liquids", "attributes": { "type": "any" } } ] }, { "concept_id": 9663, "concept_version_id": 17148, "concept_name": "Underlying (primary) cause of death: ICD10", "coding_system": { "id": 4, "name": "ICD10 codes", "description": "ICD10 Codes" }, "phenotype_id": "PH4108", "phenotype_version_id": 9326, "phenotype_name": "Aspiration pneumonitis", "code_attribute_header": [ "type" ], "codes": [ { "code": "J69.0", "description": "Pneumonitis due to food and vomit", "attributes": { "type": "any" } }, { "code": "J69.1", "description": "Pneumonitis due to oils and essences", "attributes": { "type": "any" } }, { "code": "J69.8", "description": "Pneumonitis due to other solids and liquids", "attributes": { "type": "any" } } ] }, { "concept_id": 9664, "concept_version_id": 17149, "concept_name": "Contributory (secondary) causes of death: ICD10", "coding_system": { "id": 4, "name": "ICD10 codes", "description": "ICD10 Codes" }, "phenotype_id": "PH4108", "phenotype_version_id": 9326, "phenotype_name": "Aspiration pneumonitis", "code_attribute_header": [ "type" ], "codes": [ { "code": "J69.0", "description": "Pneumonitis due to food and vomit", "attributes": { "type": "any" } }, { "code": "J69.1", "description": "Pneumonitis due to oils and essences", "attributes": { "type": "any" } }, { "code": "J69.8", "description": "Pneumonitis due to other solids and liquids", "attributes": { "type": "any" } } ] }, { "concept_id": 9665, "concept_version_id": 17150, "concept_name": "GP clinical event records", "coding_system": { "id": 6, "name": "Read codes v3", "description": "Read codes v3" }, "phenotype_id": "PH4108", "phenotype_version_id": 9326, "phenotype_name": "Aspiration pneumonitis", "code_attribute_header": [ "type" ], "codes": [ { "code": "H47..00", "description": "Pneumonitis due to inhalation of solids or liquids", "attributes": { "type": "any" } }, { "code": "H470.00", "description": "Pneumonitis due to inhalation of food or vomitus", "attributes": { "type": "any" } }, { "code": "H470000", "description": "Pneumonitis due to inhalation of regurgitated food", "attributes": { "type": "any" } }, { "code": "H470100", "description": "Pneumonitis due to inhalation of gastric secretions", "attributes": { "type": "any" } }, { "code": "H470.11", "description": "Aspiration pneumonia", "attributes": { "type": "any" } }, { "code": "H470200", "description": "Pneumonitis due to inhalation of milk", "attributes": { "type": "any" } }, { "code": "H470211", "description": "Milk inhalation pneumonitis", "attributes": { "type": "any" } }, { "code": "H470300", "description": "Pneumonitis due to inhalation of vomitus", "attributes": { "type": "any" } }, { "code": "H470311", "description": "Vomit inhalation pneumonitis", "attributes": { "type": "any" } }, { "code": "H470312", "description": "Aspiration pneumonia due to vomit", "attributes": { "type": "any" } }, { "code": "H470z00", "description": "Pneumonitis due to inhalation of food or vomitus NOS", "attributes": { "type": "any" } }, { "code": "H471.00", "description": "Pneumonitis due to inhalation of oil or essence", "attributes": { "type": "any" } }, { "code": "H471000", "description": "Lipoid pneumonia (exogenous)", "attributes": { "type": "any" } }, { "code": "H47..11", "description": "Aspiration pneumonitis", "attributes": { "type": "any" } }, { "code": "H471z00", "description": "Pneumonitis due to inhalation of oil or essence NOS", "attributes": { "type": "any" } }, { "code": "H47y.00", "description": "Pneumonitis due to inhalation of other solid or liquid", "attributes": { "type": "any" } }, { "code": "H47yz", "description": "Pneumonitis due to inhalation of solid or liquid NOS", "attributes": { "type": "any" } }, { "code": "H47yz00", "description": "Pneumonitis due to inhalation of solid or liquid NOS", "attributes": { "type": "any" } }, { "code": "H47z.00", "description": "Pneumonitis due to inhalation of solid or liquid NOS", "attributes": { "type": "any" } }, { "code": "Hyu4700", "description": "[X]Pneumonitis due to inhalation of other solids and liquids", "attributes": { "type": "any" } }, { "code": "SP13100", "description": "Other aspiration pneumonia as a complication of care", "attributes": { "type": "any" } } ] } ], "status": 1, "doi": "https://doi.org/10.48533/ytk3-ct90", "is_deleted": false, "publish_status": 2, "owner": "ieuan.scanlon", "template": { "id": 2, "name": "BHF Data Science Centre Phenotype", "description": "BHF Data Science Centre Phenotype definitions that describe a list of clinical codes, algorithms using clinical codes, or set of clinical trials. Visit the BHF Data Science Centre website to learn more: https://bhfdatasciencecentre.org", "version_id": 1 }, "versions": [ { "version_id": 9326, "version_name": "Aspiration pneumonitis", "version_date": "2026-06-08T20:06:09.999394Z", "is_published": true, "is_latest": true } ] } ]