[
  {
    "phenotype_id": "PH4123",
    "phenotype_version_id": 9341,
    "name": "Benign neoplasm of ovary",
    "definition": "A female reproductive organ benign neoplasm that is located in the ovary.\n\nUKB baseline self reported fields.\n",
    "implementation": "The earliest record across all sources is obtained.\n",
    "publications": [
      {
        "doi": "https://doi.org/10.1038/s41598-025-05838-9",
        "details": "Torralbo, Ana and Davitte, Jonathan M. and Croteau-Chonka, Damien C. and Ytsma, Cai R. and Tomlinson, Christopher and Fitzpatrick, Natalie and Chung, Sheng-Chia and Fatemifar, Ghazaleh and Cortes, Adrian S. and Richardson, Tom G. and Barclay, Matthew and Carrasco Zanini Sanchez, Julia and Finan, Chris and Hemingway, Harry and Hingorani, Aroon D. and Kuan Po Ai, Valerie and Langenberg, Claudia and Lyratzopoulos, Georgios and Lumbers, Tom and Pietzner, Maik and Shah, Anoop Dinesh and Thygesen, Johan Hilge and Zelenka, Natalie and Whittaker, John C. and Ehm, Margaret G. and Denaxas, Spiros, A Computational Framework for Defining and Validating Reproducible Phenotyping Algorithms of 313 Diseases in the UK Biobank.",
        "primary": true
      }
    ],
    "validation": "Phenotypes underwent a multi\\-layered validation approach that included a) evaluating data source concordance, b) age\\-sex incidence and baseline prevalence patterns, c) an external comparison to a representative and unselected UK EHR dataset, d) modifiable risk factor associations, and e) genetic correlations with external genome\\-wide association studies (GWAS). Results showed consistent disease distributions by age and sex, high ranked correlation with general population prevalence estimates, confirmed risk factor associations, and significant genetic correlations with external GWAS.\n",
    "citation_requirements": null,
    "created": "2026-06-08T20:06:59.534165Z",
    "author": "Torralbo, A; Davitte, J M; Croteau-Chonka, D C; Ytsma, C; Tomlinson, C; Fitzpatrick, N K; Chung, S C; Fatemifar, G; Cortes, A S; Richardson, T G; Barclay, M; Carrasco Zanini, J; Finan, C; Hemingway, H; Hingorani, A; Kuan, V; Langenberg, C; Lyratzopoulos, G; Lumbers, R T; Pietzner, M; Shah, A D; Thygesen, J H; Zelenka, N; Whittaker, J C; Ehm, M G; Denaxas, S",
    "collections": [
      {
        "name": "Phenotype Library",
        "value": 18
      },
      {
        "name": "UK Biobank",
        "value": 32
      }
    ],
    "tags": null,
    "organisation": null,
    "world_access": 1,
    "updated": "2026-06-08T20:06:59.528693Z",
    "sex": [
      {
        "name": "Female",
        "value": "2"
      }
    ],
    "type": [
      {
        "name": "Disease or syndrome",
        "value": "2"
      }
    ],
    "trials": null,
    "ontology": [
      {
        "name": "Benign neoplasm of ovary (disorder)",
        "value": 1094
      }
    ],
    "phenoflowid": null,
    "data_sources": [
      {
        "name": "UK Biobank",
        "value": 13,
        "uid": "6a9f93ad-2434-41d9-93bf-6e9d2eee04e5",
        "url": "https://healthdatagateway.org/en/dataset/700",
        "datasource_id": 700
      },
      {
        "name": "Patient Episode Dataset for Wales (PEDW)",
        "value": 40,
        "uid": "4c33a5d2-164c-41d7-9797-dc2b008cc852",
        "url": "https://healthdatagateway.org/en/dataset/318",
        "datasource_id": 318
      },
      {
        "name": "Scottish Cancer Registry (SMR06)",
        "value": 417,
        "uid": "ad36dc03-1856-44de-99b0-1af6f312d86b",
        "url": "https://healthdatagateway.org/en/dataset/79",
        "datasource_id": 79
      },
      {
        "name": "Cancer Registration Data",
        "value": 788,
        "uid": "6904a2ff-ab44-4dd6-b9ec-25d3cad29e43",
        "url": "https://healthdatagateway.org/en/dataset/880",
        "datasource_id": 880
      }
    ],
    "endorsements": null,
    "project_name": null,
    "coding_system": [
      {
        "name": "ICD10 codes",
        "value": 4
      },
      {
        "name": "Read codes v3",
        "value": 6
      }
    ],
    "corresp_author": "Ana Torralbo",
    "event_date_range": null,
    "concept_information": [
      {
        "concept_id": 9752,
        "concept_version_id": 17237,
        "concept_name": "Diagnoses - main ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4123",
        "phenotype_version_id": 9341,
        "phenotype_name": "Benign neoplasm of ovary",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "D27",
            "description": "Benign neoplasm of ovary",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N83.0",
            "description": "Follicular cyst of ovary",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N83.1",
            "description": "Corpus luteum cyst",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N83.2",
            "description": "Other and unspecified ovarian cysts",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9753,
        "concept_version_id": 17238,
        "concept_name": "Diagnoses - secondary ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4123",
        "phenotype_version_id": 9341,
        "phenotype_name": "Benign neoplasm of ovary",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "D27",
            "description": "Benign neoplasm of ovary",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N83.0",
            "description": "Follicular cyst of ovary",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N83.1",
            "description": "Corpus luteum cyst",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N83.2",
            "description": "Other and unspecified ovarian cysts",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9754,
        "concept_version_id": 17239,
        "concept_name": "Underlying (primary) cause of death: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4123",
        "phenotype_version_id": 9341,
        "phenotype_name": "Benign neoplasm of ovary",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "D27",
            "description": "Benign neoplasm of ovary",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N83.0",
            "description": "Follicular cyst of ovary",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N83.1",
            "description": "Corpus luteum cyst",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N83.2",
            "description": "Other and unspecified ovarian cysts",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9755,
        "concept_version_id": 17240,
        "concept_name": "Contributory (secondary) causes of death: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4123",
        "phenotype_version_id": 9341,
        "phenotype_name": "Benign neoplasm of ovary",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "D27",
            "description": "Benign neoplasm of ovary",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N83.0",
            "description": "Follicular cyst of ovary",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N83.1",
            "description": "Corpus luteum cyst",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N83.2",
            "description": "Other and unspecified ovarian cysts",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9756,
        "concept_version_id": 17241,
        "concept_name": "GP clinical event records",
        "coding_system": {
          "id": 6,
          "name": "Read codes v3",
          "description": "Read codes v3"
        },
        "phenotype_id": "PH4123",
        "phenotype_version_id": 9341,
        "phenotype_name": "Benign neoplasm of ovary",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "7E20300",
            "description": "Ovarian cystectomy",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7E23300",
            "description": "Open drainage of cyst of ovary",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7E25200",
            "description": "Endoscopic drainage of cyst of ovary",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7E25211",
            "description": "Laparoscopic drainage ovarian cyst",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7E29100",
            "description": "Transvaginal drainage of ovarian cyst",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "7E2B000",
            "description": "Transvaginal ultrasound guided aspiration of ovarian cyst",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B7A..00",
            "description": "Benign neoplasm of ovary",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B7A..11",
            "description": "Dermoid cyst of ovary",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B7A2.00",
            "description": "Benign teratoma of ovary",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "BB81.00",
            "description": "[M]Ovarian cystic, mucinous and serous neoplasms",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "BB81z00",
            "description": "[M]Ovarian cystic, mucinous or serous neoplasm NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "K530.00",
            "description": "Follicular cyst of ovary",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "K530.11",
            "description": "Graafian follicle cyst",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "K531.00",
            "description": "Corpus luteum cyst",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "K531000",
            "description": "Corpus luteum cyst unspecified",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "K53..11",
            "description": "Ovarian cysts",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "K531100",
            "description": "Corpus luteum cyst haemorrhage",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "K531200",
            "description": "Corpus luteum cyst rupture",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "K531z00",
            "description": "Corpus luteum cyst NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "K532.00",
            "description": "Other ovarian cysts",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "K532000",
            "description": "Corpus albicans cyst of the ovary",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "K532100",
            "description": "Theca lutein cyst of the ovary",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "K532300",
            "description": "Simple cystoma of the ovary",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "K532z00",
            "description": "Ovarian cyst NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Kyu9500",
            "description": "[X]Other and unspecified ovarian cysts",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "PC04.00",
            "description": "Developmental ovarian cyst",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "X784V",
            "description": "Developmental ovarian cyst",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "X78XE",
            "description": "Benign teratoma of ovary",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XaMnS",
            "description": "Transvaginal ultrasound guided aspiration of ovarian cyst",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XE0eZ",
            "description": "Noninflammatory disorders of the ovary, fallopian tube and broad ligament",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XE1wV",
            "description": "[M]Ovarian cystic, mucinous and serous neoplasms",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "ZV13G00",
            "description": "[V]Personal history of ovarian cyst",
            "attributes": {
              "type": "prevalent"
            }
          }
        ]
      },
      {
        "concept_id": 9757,
        "concept_version_id": 17242,
        "concept_name": "Type of cancer: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4123",
        "phenotype_version_id": 9341,
        "phenotype_name": "Benign neoplasm of ovary",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "D27",
            "description": "Benign neoplasm of ovary",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N83.0",
            "description": "Follicular cyst of ovary",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N83.1",
            "description": "Corpus luteum cyst",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N83.2",
            "description": "Other and unspecified ovarian cysts",
            "attributes": {
              "type": "any"
            }
          }
        ]
      }
    ],
    "status": 1,
    "doi": "https://doi.org/10.48533/crq5-b666",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 2,
      "name": "BHF Data Science Centre Phenotype",
      "description": "BHF Data Science Centre Phenotype definitions that describe a list of clinical codes, algorithms using clinical codes, or set of clinical trials. Visit the BHF Data Science Centre website to learn more: https://bhfdatasciencecentre.org",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 9341,
        "version_name": "Benign neoplasm of ovary",
        "version_date": "2026-06-08T20:06:59.542175Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]