[
  {
    "phenotype_id": "PH4154",
    "phenotype_version_id": 9372,
    "name": "Delirium, not induced by alcohol and other psychoactive substances",
    "definition": "Delirium, not induced by alcohol and other psychoactive substances\n\nUKB baseline self reported fields.\n",
    "implementation": "The earliest record across all sources is obtained.\n",
    "publications": [
      {
        "doi": "https://doi.org/10.1038/s41598-025-05838-9",
        "details": "Torralbo, Ana and Davitte, Jonathan M. and Croteau-Chonka, Damien C. and Ytsma, Cai R. and Tomlinson, Christopher and Fitzpatrick, Natalie and Chung, Sheng-Chia and Fatemifar, Ghazaleh and Cortes, Adrian S. and Richardson, Tom G. and Barclay, Matthew and Carrasco Zanini Sanchez, Julia and Finan, Chris and Hemingway, Harry and Hingorani, Aroon D. and Kuan Po Ai, Valerie and Langenberg, Claudia and Lyratzopoulos, Georgios and Lumbers, Tom and Pietzner, Maik and Shah, Anoop Dinesh and Thygesen, Johan Hilge and Zelenka, Natalie and Whittaker, John C. and Ehm, Margaret G. and Denaxas, Spiros, A Computational Framework for Defining and Validating Reproducible Phenotyping Algorithms of 313 Diseases in the UK Biobank.",
        "primary": true
      }
    ],
    "validation": "Phenotypes underwent a multi\\-layered validation approach that included a) evaluating data source concordance, b) age\\-sex incidence and baseline prevalence patterns, c) an external comparison to a representative and unselected UK EHR dataset, d) modifiable risk factor associations, and e) genetic correlations with external genome\\-wide association studies (GWAS). Results showed consistent disease distributions by age and sex, high ranked correlation with general population prevalence estimates, confirmed risk factor associations, and significant genetic correlations with external GWAS.\n",
    "citation_requirements": null,
    "created": "2026-06-08T20:08:35.244279Z",
    "author": "Torralbo, A; Davitte, J M; Croteau-Chonka, D C; Ytsma, C; Tomlinson, C; Fitzpatrick, N K; Chung, S C; Fatemifar, G; Cortes, A S; Richardson, T G; Barclay, M; Carrasco Zanini, J; Finan, C; Hemingway, H; Hingorani, A; Kuan, V; Langenberg, C; Lyratzopoulos, G; Lumbers, R T; Pietzner, M; Shah, A D; Thygesen, J H; Zelenka, N; Whittaker, J C; Ehm, M G; Denaxas, S",
    "collections": [
      {
        "name": "Phenotype Library",
        "value": 18
      },
      {
        "name": "UK Biobank",
        "value": 32
      }
    ],
    "tags": null,
    "organisation": null,
    "world_access": 1,
    "updated": "2026-06-08T20:08:35.234976Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Disease or syndrome",
        "value": "2"
      }
    ],
    "trials": null,
    "ontology": [
      {
        "name": "Subacute delirium (disorder)",
        "value": 711755
      }
    ],
    "phenoflowid": null,
    "data_sources": [
      {
        "name": "UK Biobank",
        "value": 13,
        "uid": "6a9f93ad-2434-41d9-93bf-6e9d2eee04e5",
        "url": "https://healthdatagateway.org/en/dataset/700",
        "datasource_id": 700
      },
      {
        "name": "Patient Episode Dataset for Wales (PEDW)",
        "value": 40,
        "uid": "4c33a5d2-164c-41d7-9797-dc2b008cc852",
        "url": "https://healthdatagateway.org/en/dataset/318",
        "datasource_id": 318
      },
      {
        "name": "Scottish Cancer Registry (SMR06)",
        "value": 417,
        "uid": "ad36dc03-1856-44de-99b0-1af6f312d86b",
        "url": "https://healthdatagateway.org/en/dataset/79",
        "datasource_id": 79
      },
      {
        "name": "Cancer Registration Data",
        "value": 788,
        "uid": "6904a2ff-ab44-4dd6-b9ec-25d3cad29e43",
        "url": "https://healthdatagateway.org/en/dataset/880",
        "datasource_id": 880
      }
    ],
    "endorsements": null,
    "project_name": null,
    "coding_system": [
      {
        "name": "ICD10 codes",
        "value": 4
      },
      {
        "name": "Read codes v3",
        "value": 6
      }
    ],
    "corresp_author": "Ana Torralbo",
    "event_date_range": null,
    "concept_information": [
      {
        "concept_id": 9962,
        "concept_version_id": 17447,
        "concept_name": "Diagnoses - main ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4154",
        "phenotype_version_id": 9372,
        "phenotype_name": "Delirium, not induced by alcohol and other psychoactive substances",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "F05",
            "description": "Delirium, not induced by alcohol and other psychoactive substances",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9963,
        "concept_version_id": 17448,
        "concept_name": "Diagnoses - secondary ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4154",
        "phenotype_version_id": 9372,
        "phenotype_name": "Delirium, not induced by alcohol and other psychoactive substances",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "F05",
            "description": "Delirium, not induced by alcohol and other psychoactive substances",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9964,
        "concept_version_id": 17449,
        "concept_name": "Underlying (primary) cause of death: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4154",
        "phenotype_version_id": 9372,
        "phenotype_name": "Delirium, not induced by alcohol and other psychoactive substances",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "F05",
            "description": "Delirium, not induced by alcohol and other psychoactive substances",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9965,
        "concept_version_id": 17450,
        "concept_name": "Contributory (secondary) causes of death: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4154",
        "phenotype_version_id": 9372,
        "phenotype_name": "Delirium, not induced by alcohol and other psychoactive substances",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "F05",
            "description": "Delirium, not induced by alcohol and other psychoactive substances",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9966,
        "concept_version_id": 17451,
        "concept_name": "GP clinical event records",
        "coding_system": {
          "id": 6,
          "name": "Read codes v3",
          "description": "Read codes v3"
        },
        "phenotype_id": "PH4154",
        "phenotype_version_id": 9372,
        "phenotype_name": "Delirium, not induced by alcohol and other psychoactive substances",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "2233.00",
            "description": "O/E - delirious",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E001100",
            "description": "Presenile dementia with delirium",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E003.00",
            "description": "Senile dementia with delirium",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E004100",
            "description": "Arteriosclerotic dementia with delirium",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E030.00",
            "description": "Acute confusional state",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E030000",
            "description": "Acute confusional state, post traumatic",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E030100",
            "description": "Acute confusional state, of infective origin",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E030.11",
            "description": "Delirium - acute organic",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E030200",
            "description": "Acute confusional state, of endocrine origin",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E030300",
            "description": "Acute confusional state, of metabolic origin",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E030400",
            "description": "Acute confusional state, of cerebrovascular origin",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E031.00",
            "description": "Subacute confusional state",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E031000",
            "description": "Subacute confusional state, post traumatic",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E031100",
            "description": "Subacute confusional state, of infective origin",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E031.11",
            "description": "Delirium - subacute organic",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E031300",
            "description": "Subacute confusional state, of metabolic origin",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E031400",
            "description": "Subacute confusional state, of cerebrovascular origin",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E031z00",
            "description": "Subacute confusional state NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu04.00",
            "description": "[X]Delirium, not induced by alcohol+other psychoactive subs",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu04000",
            "description": "[X]Delirium not superimposed on dementia, so described",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu04100",
            "description": "[X]Delirium superimposed on dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu04.11",
            "description": "[X]Acute / subacute brain syndrome",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu04.12",
            "description": "[X]Acute / subacute confusional state, nonalcoholic",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu04.13",
            "description": "[X]Acute / subacute infective psychosis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu04.14",
            "description": "[X]Acute / subacute organic reaction",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu04.15",
            "description": "[X]Acute / subacute psycho-organic reaction",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu04y00",
            "description": "[X]Other delirium",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu04z00",
            "description": "[X]Delirium, unspecified",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XE1Z7",
            "description": "[X]Delirium, not induced by alcohol and other psychoactive subs",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XE1Z8",
            "description": "[X]Other delirium",
            "attributes": {
              "type": "any"
            }
          }
        ]
      }
    ],
    "status": 1,
    "doi": "https://doi.org/10.48533/m153-6c51",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 2,
      "name": "BHF Data Science Centre Phenotype",
      "description": "BHF Data Science Centre Phenotype definitions that describe a list of clinical codes, algorithms using clinical codes, or set of clinical trials. Visit the BHF Data Science Centre website to learn more: https://bhfdatasciencecentre.org",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 9372,
        "version_name": "Delirium, not induced by alcohol and other psychoactive substances",
        "version_date": "2026-06-08T20:08:35.253064Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]