[
  {
    "phenotype_id": "PH4156",
    "phenotype_version_id": 9374,
    "name": "Dementia (excluding Alzheimer's)",
    "definition": "A cognitive disorder resulting from a loss of brain function affecting memory, thinking, language, judgement and behavior, not including Alzheimer's.\n\nUKB baseline self reported fields.\n",
    "implementation": "The earliest record across all sources is obtained.\n",
    "publications": [
      {
        "doi": "https://doi.org/10.1038/s41598-025-05838-9",
        "details": "Torralbo, Ana and Davitte, Jonathan M. and Croteau-Chonka, Damien C. and Ytsma, Cai R. and Tomlinson, Christopher and Fitzpatrick, Natalie and Chung, Sheng-Chia and Fatemifar, Ghazaleh and Cortes, Adrian S. and Richardson, Tom G. and Barclay, Matthew and Carrasco Zanini Sanchez, Julia and Finan, Chris and Hemingway, Harry and Hingorani, Aroon D. and Kuan Po Ai, Valerie and Langenberg, Claudia and Lyratzopoulos, Georgios and Lumbers, Tom and Pietzner, Maik and Shah, Anoop Dinesh and Thygesen, Johan Hilge and Zelenka, Natalie and Whittaker, John C. and Ehm, Margaret G. and Denaxas, Spiros, A Computational Framework for Defining and Validating Reproducible Phenotyping Algorithms of 313 Diseases in the UK Biobank.",
        "primary": true
      }
    ],
    "validation": "Phenotypes underwent a multi\\-layered validation approach that included a) evaluating data source concordance, b) age\\-sex incidence and baseline prevalence patterns, c) an external comparison to a representative and unselected UK EHR dataset, d) modifiable risk factor associations, and e) genetic correlations with external genome\\-wide association studies (GWAS). Results showed consistent disease distributions by age and sex, high ranked correlation with general population prevalence estimates, confirmed risk factor associations, and significant genetic correlations with external GWAS.\n",
    "citation_requirements": null,
    "created": "2026-06-08T20:08:44.409971Z",
    "author": "Torralbo, A; Davitte, J M; Croteau-Chonka, D C; Ytsma, C; Tomlinson, C; Fitzpatrick, N K; Chung, S C; Fatemifar, G; Cortes, A S; Richardson, T G; Barclay, M; Carrasco Zanini, J; Finan, C; Hemingway, H; Hingorani, A; Kuan, V; Langenberg, C; Lyratzopoulos, G; Lumbers, R T; Pietzner, M; Shah, A D; Thygesen, J H; Zelenka, N; Whittaker, J C; Ehm, M G; Denaxas, S",
    "collections": [
      {
        "name": "Phenotype Library",
        "value": 18
      },
      {
        "name": "UK Biobank",
        "value": 32
      }
    ],
    "tags": null,
    "organisation": null,
    "world_access": 1,
    "updated": "2026-06-08T20:08:44.404246Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Disease or syndrome",
        "value": "2"
      }
    ],
    "trials": null,
    "ontology": [
      {
        "name": "Dementia (disorder)",
        "value": 723040
      }
    ],
    "phenoflowid": null,
    "data_sources": [
      {
        "name": "UK Biobank",
        "value": 13,
        "uid": "6a9f93ad-2434-41d9-93bf-6e9d2eee04e5",
        "url": "https://healthdatagateway.org/en/dataset/700",
        "datasource_id": 700
      },
      {
        "name": "Patient Episode Dataset for Wales (PEDW)",
        "value": 40,
        "uid": "4c33a5d2-164c-41d7-9797-dc2b008cc852",
        "url": "https://healthdatagateway.org/en/dataset/318",
        "datasource_id": 318
      },
      {
        "name": "Scottish Cancer Registry (SMR06)",
        "value": 417,
        "uid": "ad36dc03-1856-44de-99b0-1af6f312d86b",
        "url": "https://healthdatagateway.org/en/dataset/79",
        "datasource_id": 79
      },
      {
        "name": "Cancer Registration Data",
        "value": 788,
        "uid": "6904a2ff-ab44-4dd6-b9ec-25d3cad29e43",
        "url": "https://healthdatagateway.org/en/dataset/880",
        "datasource_id": 880
      }
    ],
    "endorsements": null,
    "project_name": null,
    "coding_system": [
      {
        "name": "ICD10 codes",
        "value": 4
      },
      {
        "name": "Read codes v3",
        "value": 6
      }
    ],
    "corresp_author": "Ana Torralbo",
    "event_date_range": null,
    "concept_information": [
      {
        "concept_id": 9973,
        "concept_version_id": 17458,
        "concept_name": "Diagnoses - main ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4156",
        "phenotype_version_id": 9374,
        "phenotype_name": "Dementia (excluding Alzheimer's)",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "F01",
            "description": "Vascular dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F03",
            "description": "Unspecified dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F05.1",
            "description": "Delirium superimposed on dementia",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9974,
        "concept_version_id": 17459,
        "concept_name": "Diagnoses - secondary ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4156",
        "phenotype_version_id": 9374,
        "phenotype_name": "Dementia (excluding Alzheimer's)",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "F01",
            "description": "Vascular dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F03",
            "description": "Unspecified dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F05.1",
            "description": "Delirium superimposed on dementia",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9975,
        "concept_version_id": 17460,
        "concept_name": "Underlying (primary) cause of death: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4156",
        "phenotype_version_id": 9374,
        "phenotype_name": "Dementia (excluding Alzheimer's)",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "F01",
            "description": "Vascular dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F03",
            "description": "Unspecified dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F05.1",
            "description": "Delirium superimposed on dementia",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9976,
        "concept_version_id": 17461,
        "concept_name": "Contributory (secondary) causes of death: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4156",
        "phenotype_version_id": 9374,
        "phenotype_name": "Dementia (excluding Alzheimer's)",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "F01",
            "description": "Vascular dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F03",
            "description": "Unspecified dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "F05.1",
            "description": "Delirium superimposed on dementia",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 9977,
        "concept_version_id": 17462,
        "concept_name": "GP clinical event records",
        "coding_system": {
          "id": 6,
          "name": "Read codes v3",
          "description": "Read codes v3"
        },
        "phenotype_id": "PH4156",
        "phenotype_version_id": 9374,
        "phenotype_name": "Dementia (excluding Alzheimer's)",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "1461.00",
            "description": "H/O: dementia",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "66h..00",
            "description": "Dementia monitoring",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "6AB..00",
            "description": "Dementia annual review",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "8CMZ.00",
            "description": "Dementia care plan",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "9hD..00",
            "description": "Exception reporting: dementia quality indicators",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "9hD0.00",
            "description": "Excepted from dementia quality indicators: Patient unsuitabl",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "9hD1.00",
            "description": "Excepted from dementia quality indicators: Informed dissent",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "9Ou..00",
            "description": "Dementia monitoring administration",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "9Ou1.00",
            "description": "Dementia monitoring first letter",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "9Ou2.00",
            "description": "Dementia monitoring second letter",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "9Ou3.00",
            "description": "Dementia monitoring third letter",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "9Ou4.00",
            "description": "Dementia monitoring verbal invite",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "9Ou5.00",
            "description": "Dementia monitoring telephone invite",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "E00..00",
            "description": "Senile and presenile organic psychotic conditions",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E000.00",
            "description": "Uncomplicated senile dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E001.00",
            "description": "Presenile dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E001000",
            "description": "Uncomplicated presenile dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E00..11",
            "description": "Senile dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E001100",
            "description": "Presenile dementia with delirium",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E00..12",
            "description": "Senile/presenile dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E001200",
            "description": "Presenile dementia with paranoia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E001300",
            "description": "Presenile dementia with depression",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E001z00",
            "description": "Presenile dementia NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E002.00",
            "description": "Senile dementia with depressive or paranoid features",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E002000",
            "description": "Senile dementia with paranoia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E002100",
            "description": "Senile dementia with depression",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E002z00",
            "description": "Senile dementia with depressive or paranoid features NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E003.00",
            "description": "Senile dementia with delirium",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E004.00",
            "description": "Arteriosclerotic dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E004000",
            "description": "Uncomplicated arteriosclerotic dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E004100",
            "description": "Arteriosclerotic dementia with delirium",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E004.11",
            "description": "Multi infarct dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E004200",
            "description": "Arteriosclerotic dementia with paranoia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E004300",
            "description": "Arteriosclerotic dementia with depression",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E004z00",
            "description": "Arteriosclerotic dementia NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E00y.00",
            "description": "Other senile and presenile organic psychoses",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E00y.11",
            "description": "Presbyophrenic psychosis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E00z.00",
            "description": "Senile or presenile psychoses NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "E041.00",
            "description": "Dementia in conditions EC",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu01.00",
            "description": "[X]Vascular dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu01000",
            "description": "[X]Vascular dementia of acute onset",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu01100",
            "description": "[X]Multi-infarct dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu01.11",
            "description": "[X]Arteriosclerotic dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu01111",
            "description": "[X]Predominantly cortical dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu01200",
            "description": "[X]Subcortical vascular dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu01300",
            "description": "[X]Mixed cortical and subcortical vascular dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu01y00",
            "description": "[X]Other vascular dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu01z00",
            "description": "[X]Vascular dementia, unspecified",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu02z00",
            "description": "[X] Unspecified dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu02z11",
            "description": "[X] Presenile dementia NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu02z12",
            "description": "[X] Presenile psychosis NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu02z13",
            "description": "[X] Primary degenerative dementia NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu02z14",
            "description": "[X] Senile dementia NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu02z15",
            "description": "[X] Senile psychosis NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu02z16",
            "description": "[X] Senile dementia, depressed or paranoid type",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Eu04100",
            "description": "[X]Delirium superimposed on dementia",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XaaBZ",
            "description": "Dementia care plan",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XaLFf",
            "description": "Exception reporting: dementia quality indicators",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "XaLFo",
            "description": "Excepted from dementia quality indicators: Patient unsuitable",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "XaLFp",
            "description": "Excepted from dementia quality indicators: Informed dissent",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "XaMFy",
            "description": "Dementia monitoring administration",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "XaMG0",
            "description": "Dementia monitoring first letter",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "XaMGF",
            "description": "Dementia annual review",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "XaMGG",
            "description": "Dementia monitoring second letter",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "XaMGI",
            "description": "Dementia monitoring third letter",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "XaMGJ",
            "description": "Dementia monitoring verbal invite",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "XaMGK",
            "description": "Dementia monitoring telephone invite",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "XaMJC",
            "description": "Dementia monitoring",
            "attributes": {
              "type": "prevalent"
            }
          },
          {
            "code": "XE1Xr",
            "description": "Senile and presenile organic psychotic conditions",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XE1Xt",
            "description": "Other senile and presenile organic psychoses",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "ZS7C500",
            "description": "Language disorder of dementia",
            "attributes": {
              "type": "any"
            }
          }
        ]
      }
    ],
    "status": 1,
    "doi": "https://doi.org/10.48533/q32d-cb06",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 2,
      "name": "BHF Data Science Centre Phenotype",
      "description": "BHF Data Science Centre Phenotype definitions that describe a list of clinical codes, algorithms using clinical codes, or set of clinical trials. Visit the BHF Data Science Centre website to learn more: https://bhfdatasciencecentre.org",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 9374,
        "version_name": "Dementia (excluding Alzheimer's)",
        "version_date": "2026-06-08T20:08:44.420428Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]