[
  {
    "phenotype_id": "PH420",
    "phenotype_version_id": 840,
    "name": "Hormone Replacement Drugs",
    "definition": "Patient level data were extracted from the General Practice Research Database (GPRD), which contains anonymised, patient based data on morbidity, prescribing, treatment, and referral collected from over 500 general practices, covering about 7% of the UK population (4.4 million patients).14 Data are in Read code format—a hierarchical system used to code clinical data. Additional data on prescriptions and test results are available as free-text entries. We selected a sample of 148 practices that provided data to the GPRD continuously between January 2000 and December 2007, structured to include a range of list (patient panel) sizes. Selected practices were nationally representative in terms of patient sex and age distribution and area socioeconomic deprivation but had a relatively large average list size, reflecting a bias towards larger practices in the GPRD. Overall, the selected practices performed marginally better than national practices on the clinical indicators in the Quality and Outcomes Framework. A random selection of 4500 patients registered for at least one day between 1 January 2000 and 31 December 2007 was drawn from each practice. For practices with fewer than 4501 patients, all patients were selected. The final sample consisted of 653 500 patients. Patients with relevant conditions were identified from their diagnostic Read codes. Patients for whom targets were met were identified from the relevant Read codes and free-text terms.\n\n\n\n\n\n\n\n\n",
    "implementation": "",
    "publications": [
      {
        "doi": null,
        "details": "Tim Doran, Evangelos Kontopantelis, Jose M Valderas, Stephen Campbell, Martin Roland, Chris Salisbury, David Reeves, Effect of financial incentives on incentivised and non-incentivised clinical activities: longitudinal analysis of data from the UK Quality and Outcomes Framework. BMJ, 342:d3590, 2011."
      }
    ],
    "validation": "",
    "citation_requirements": "",
    "created": "2021-10-06T16:18:46.577956Z",
    "author": "Tim Doran, Evangelos Kontopantelis, Jose M Valderas, Stephen Campbell, Martin Roland, Chris Salisbury, David Reeves",
    "collections": [
      {
        "name": "ClinicalCodes Repository",
        "value": 25
      },
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": null,
    "world_access": 1,
    "updated": "2021-10-06T16:18:46.577984Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Drug",
        "value": "3"
      }
    ],
    "ontology": null,
    "phenoflowid": "",
    "data_sources": [
      {
        "name": "CPRD GOLD",
        "value": 5,
        "uid": "a29feafa-7bdd-44e9-b977-c9d26425e67f",
        "url": "https://healthdatagateway.org/en/dataset/694",
        "datasource_id": 694
      }
    ],
    "coding_system": [
      {
        "name": "GPRD product codes",
        "value": 14
      }
    ],
    "event_date_range": "01/01/2000 - 31/12/2007",
    "concept_information": [
      {
        "concept_id": 1767,
        "concept_version_id": 4672,
        "concept_name": "Hormone Replacement Drugs - Primary Care",
        "coding_system": {
          "id": 14,
          "name": "GPRD product codes",
          "description": "GPRD product codes"
        },
        "phenotype_id": "PH420",
        "phenotype_version_id": 840,
        "phenotype_name": "Hormone Replacement Drugs",
        "code_attribute_header": [
          "Entity type",
          "Category",
          "Coding System (GPRD_product_code)"
        ],
        "codes": [
          {
            "code": "10046001",
            "description": "ADGYN ESTRO tabs 2mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10092001",
            "description": "PHYTO PROGESTERONE crm 3%",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10098001",
            "description": "PRO-JUVEN crm 3%",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10130001",
            "description": "PHYTO PROGESTERONE crm 1.5%",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10196001",
            "description": "ESTRADIOL + DYDROGESTERONE tabs 1mg + 5mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10370001",
            "description": "ESTRADIOL TWICE WEEKLY patch 75micrograms/24 hours (2.25mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10372001",
            "description": "ESTRADERM MX patch 75micrograms/24 hours (2.25mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10417001",
            "description": "ESTRADIOL + NORETHISTERONE ACETATE (continuous combined) tabs 4mg + 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10418001",
            "description": "ESTRADIOL + LEVONORGESTREL - ONCE WEEKLY patch 50micrograms + 10micrograms/24 hours",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10499001",
            "description": "MENORING 50 vaginal ring 50micrograms/24 hours(12.4mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10530001",
            "description": "NOVOFEM tabs 1mg + (1mg + 1mg)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10599001",
            "description": "ESTRADIOL HEMIHYDRATE + NORETHISTERONE tabs 1mg + 0.5mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10600001",
            "description": "KLIOVANCE tabs 1mg + 0.5mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10639001",
            "description": "ESTRADIOL tabs 4mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10640001",
            "description": "ESTRADIOL + DYDROGESTERONE tabs 1mg + 10mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10641001",
            "description": "ESTRADIOL + DYDROGESTERONE tabs 2mg + 10mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10642001",
            "description": "ESTRADIOL + DYDROGESTERONE tabs 2mg + 20mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10678001",
            "description": "FEMSEVEN SEQUI patch",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10746001",
            "description": "PRO-GEST crm",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10783001",
            "description": "NUVELLE TS patch",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10787001",
            "description": "ESTRADIOL & (ESTRADIOL + LEVONORGESTREL) TWICE WEEKLY patch 80mcg/24hrs + (50mcg+20mcg/24hr)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10790001",
            "description": "DERMESTRIL SEPTEM patch 25micrograms/24 hours",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10790002",
            "description": "DERMESTRIL SEPTEM patch 50micrograms/24 hours",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10790003",
            "description": "DERMESTRIL SEPTEM patch 75micrograms/24 hours",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "1088001",
            "description": "ESTRADIOL implant 25mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "1088002",
            "description": "ESTRADIOL implant 50mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "1088003",
            "description": "ESTRADIOL implant 100mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10917001",
            "description": "DERMESTRIL patch 25micrograms/24 hours (2mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10917002",
            "description": "DERMESTRIL patch 50micrograms/24 hours (4mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "10917003",
            "description": "DERMESTRIL patch 100micrograms/24 hours (8mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "1102001",
            "description": "MENOPHASE tabs",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "11062001",
            "description": "ESTRADIOL HEMIHYDRATE nasal spray 150micrograms/actuation",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "11064001",
            "description": "AERODIOL nasal spray 150micrograms/actuation",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "1107001",
            "description": "PREMPAK -C 0.625 tabs",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "11084001",
            "description": "SANDRENA gel 0.1%",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "11087001",
            "description": "ESTRADIOL VALERATE + NORETHISTERONE (continuous combined) tabs 2mg + 0.7mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "11110001",
            "description": "EVOREL CONTI patch (50mcg + 170mcg)/24 hr",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "11112001",
            "description": "EVOREL SEQUI patch",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "11112002",
            "description": "EVOREL SEQUI patch 50mcg/24 hours (3.2mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "11164001",
            "description": "PROGYNOVA TS 50 patch 50mcg/24hours (3.8 mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "11171001",
            "description": "ELLESTE-SOLO MX 40 patch 40micrograms/24 hours (1.25mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "11173001",
            "description": "ELLESTE-SOLO MX 80 patch 80mcg/24 hours (2.5mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "11438001",
            "description": "PHYTO PROGESTERONE crm",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "11457001",
            "description": "RALOXIFENE HCl tabs 60mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "1159001",
            "description": "PREMPAK 1.25 tabs",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "1160001",
            "description": "PREMPAK -C 1.25 tabs",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "11668001",
            "description": "ESTRADIOL TWICE WEEKLY patch 75micrograms/24 hours (2.25mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "11668002",
            "description": "ESTRADIOL TWICE WEEKLY patch 100mcg/24 hours (3.0mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "11670001",
            "description": "FEMSEVEN 75 patch 75micrograms/24 hours (2.25mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "11672001",
            "description": "FEMSEVEN 100 patch 100mcg/24 hours (3.0mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "11679001",
            "description": "ELLESTE-DUET CONTI tabs 2mg + 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "11792001",
            "description": "FEMOSTON CONTI tabs 1mg + 5mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "12046001",
            "description": "CONJUGATED OESTROGENS EQUINE + MEDROXYPROGESTERONE ACETATE tabs 625micrograms + 10mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "12240001",
            "description": "ETHINYLESTRADIOL tabs 2micrograms",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "12449001",
            "description": "CONJUGATED OESTROGENS EQUINE + MEDROXYPROGESTERONE ACETATE (continuous combined) tabs 300micrograms ",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "12450001",
            "description": "PREMIQUE LOW DOSE tabs 300micrograms + 1.5mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "1271001",
            "description": "MIXOGEN tabs",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "12948001",
            "description": "ESTRADIOL TWICE WEEKLY patch 25 micrograms/24 hours (0.39mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "12949001",
            "description": "ESTRADIOL TWICE WEEKLY transdermal patch 37.5micrograms/24 hours",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "12950001",
            "description": "ESTRADIOL TWICE WEEKLY patch 50 micrograms/24 hours (0.78mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "12951001",
            "description": "ESTRADIOL TWICE WEEKLY patch 75 micrograms/24 hours (1.17mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "12952001",
            "description": "ESTRADIOL TWICE WEEKLY patch 100 micrograms/24 hours (1.56mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "12953001",
            "description": "ESTRADOT patch 25 micrograms/24 hours (0.39mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "12954001",
            "description": "ESTRADOT patch 37.5micrograms/24hours (0.585mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "12955001",
            "description": "ESTRADOT patch 50 micrograms/24 hours (0.78mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "12956001",
            "description": "ESTRADOT patch 75 micrograms/24 hours (1.17mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "12957001",
            "description": "ESTRADOT patch 100 micrograms/24 hours (1.56mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "13167001",
            "description": "DROSPIRENONE + ESTRADIOL tabs 2mg + 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "13168001",
            "description": "ANGELIQ FC tab",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "1328001",
            "description": "BENZTRONE inj 1mg/ml",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "1328002",
            "description": "BENZTRONE inj 5mg/ml",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "13941001",
            "description": "BEDOL tabs 2mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "13949001",
            "description": "CLINORETTE tabs 2mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "14023001",
            "description": "ESTRADIOL transdermal patch 25micrograms/24 hours",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "14024001",
            "description": "ESTRADIOL transdermal patch 50micrograms/24 hours",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "14025001",
            "description": "ESTRADIOL transdermal patch 75micrograms/24 hours",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "14026001",
            "description": "ESTRADIOL transdermal patch 100micrograms/24 hours",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "14032001",
            "description": "ESTRADIOL TWICE WEEKLY transdermal patch 25micrograms/24 hours",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "14033001",
            "description": "ESTRADIOL ONCE WEEKLY transdermal patch 50micrograms/24 hours",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "14034001",
            "description": "ESTRADIOL TWICE WEEKLY transdermal patch 50micrograms/24 hours",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "14035001",
            "description": "ESTRADIOL TWICE WEEKLY transdermal patch 75micrograms/24 hours",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "14036001",
            "description": "ESTRADIOL ONCE WEEKLY transdermal patch 100micrograms/24 hours",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "14037001",
            "description": "ESTRADIOL TWICE WEEKLY transdermal patch 100micrograms/24 hours",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "14268001",
            "description": "ETHINYLESTRADIOL caps",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "1531009",
            "description": "ESTRADIOL implant 25mg [ORGANON]",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "1531010",
            "description": "ESTRADIOL implant 50mg [ORGANON]",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "1531011",
            "description": "ESTRADIOL implant 100mg [ORGANON]",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "2006001",
            "description": "ETHINYLESTRADIOL tabs 10micrograms",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "2006002",
            "description": "ETHINYLESTRADIOL tabs 20micrograms",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "2052007",
            "description": "PREMARIN 0.625MG/NORGESTREL 0.15MG MG TAB",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "2234001",
            "description": "CLIMAGEST tabs 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "2234002",
            "description": "CLIMAGEST tabs 2mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "2237001",
            "description": "ZUMENON tabs 2mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "2237002",
            "description": "ZUMENON tabs 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "2240001",
            "description": "ESTRADIOL + (ESTRADIOL + NORETHISTERONE ACETATE) - TWICE WEEKLY patch 50mcg/24 hr + (50mcg+250mcg/24",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "2240002",
            "description": "ESTRADIOL + (ESTRADIOL + NORETHISTERONE ACETATE) - TWICE WEEKLY treatment pack",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "2240003",
            "description": "ESTRADIOL + (ESTRADIOL + NORETHISTERONE ACETATE) - TWICE WEEKLY patch 50mcg/24 hr + (50mcg+170mcg/24",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "2267001",
            "description": "ESTRACOMBI TTS patch",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "236001",
            "description": "ESTRADIOL + LEVONORGESTREL - TWICE WEEKLY patch 50micrograms + 20micrograms/24 hours",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "2374001",
            "description": "ESTRADIOL VALERATE & (ESTRADIOL VALERATE + NORETHISTERONE) tabs 1mg + (1mg + 1mg)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "2374002",
            "description": "ESTRADIOL VALERATE & (ESTRADIOL VALERATE + NORETHISTERONE) tabs 2mg + (2mg + 1 mg)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "2374003",
            "description": "ESTRADIOL VALERATE & (ESTRADIOL VALERATE + NORETHISTERONE) tabs 2mg + 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "2517001",
            "description": "TRISEQUENS tabs",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "2517002",
            "description": "TRISEQUENS forte tabs",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "2541001",
            "description": "CYCLO-PROGYNOVA tabs 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "2541002",
            "description": "CYCLO-PROGYNOVA tabs 2mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "2542001",
            "description": "PROGYNOVA tabs 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "2542002",
            "description": "PROGYNOVA tabs 2mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "2799009",
            "description": "ETHINYLESTRADIOL tabs 10micrograms [CELLTECH]",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "3251001",
            "description": "ESTRADIOL inj 1mg/ml",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "3251002",
            "description": "ESTRADIOL inj 5mg/ml",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "3252001",
            "description": "ESTRADIOL tabs 2mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "3252002",
            "description": "ESTRADIOL tabs 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "3252003",
            "description": "ESTRADIOL patch 40micrograms/24 hours (1.25mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "3253001",
            "description": "ESTRADIOL + ESTRONE & ESTRIOL tabs",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "3253007",
            "description": "PREMARIN 1.25MG/NORGESTREL 0.15MG MG TAB",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "3254001",
            "description": "HORMONIN tabs",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "3255001",
            "description": "ESTRIOL tabs 250micrograms",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "3255002",
            "description": "ESTRIOL tabs 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "3390001",
            "description": "CONJUGATED OESTROGENS EQUINE tabs 625micrograms",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "3390002",
            "description": "CONJUGATED OESTROGENS EQUINE tabs 1.25mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "3390003",
            "description": "CONJUGATED OESTROGENS EQUINE tabs 2.5mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "3607001",
            "description": "DIENESTROL tabs 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "3607002",
            "description": "DIENESTROL tabs 5mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "397009",
            "description": "ETHINYLESTRADIOL tabs 10micrograms [UCB]",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "397010",
            "description": "ETHINYLESTRADIOL tabs 50micrograms [UCB]",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "397011",
            "description": "ETHINYLESTRADIOL tabs 1mg [UCB]",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "428001",
            "description": "HARMOGEN tabs 1.5mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "4301001",
            "description": "NORGESTREL & CONJUGATED OESTROGENS (EQUINE) tabs 150micrograms + 625micrograms",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "4301002",
            "description": "NORGESTREL & CONJUGATED OESTROGENS (EQUINE) tabs 150micrograms + 1.25mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "4342001",
            "description": "ESTRADIOL VALERATE & (ESTRADIOL VALERATE + LEVONORGESTREL) tabs 2mg + (2mg + 75micrograms)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "4342002",
            "description": "ESTRADIOL VALERATE & (ESTRADIOL VALERATE + LEVONORGESTREL) tabs 1mg + (1mg + 250micrograms)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "4396001",
            "description": "NUVELLE tabs",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "4636007",
            "description": "OVESTIN .25 MG TAB",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "4659001",
            "description": "QUINESTRADOL caps 250micrograms",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "4660001",
            "description": "PENTOVIS caps 250micrograms",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "4661001",
            "description": "QUINESTROL tabs 4mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "4662001",
            "description": "ESTROVIS tabs 4mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "4828009",
            "description": "ETHINYLESTRADIOL tabs 2micrograms [UCB]",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "5028001",
            "description": "ESTROPIPATE tabs 1.5mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "5262001",
            "description": "CLIMAVAL tabs 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "5262002",
            "description": "CLIMAVAL tabs 2mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "5480001",
            "description": "ESTRADIOL TWICE WEEKLY patch 50mcg/24 hours (3.2mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "5480002",
            "description": "ESTRADIOL TWICE WEEKLY patch 25mcg/24 hours (1.6mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "5480003",
            "description": "ESTRADIOL TWICE WEEKLY patch 75micrograms/24 hours(4.8mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "5481001",
            "description": "ESTRADIOL TWICE WEEKLY patch 25micrograms/24 hours (2mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "5481002",
            "description": "ESTRADIOL TWICE WEEKLY patch 100micrograms/24 hours (8mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "5481003",
            "description": "ESTRADIOL TWICE WEEKLY patch 25micrograms/24 hours (2mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "5482001",
            "description": "ESTRAPAK 50 patch+tab 50mcg/24hours(4mg/unit) + 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "5483001",
            "description": "ESTRADERM TTS patch 25micrograms/24 hours (2mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "5483002",
            "description": "ESTRADERM TTS patch 50micrograms/24 hours (4mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "5483003",
            "description": "ESTRADERM TTS patch 100micrograms/24 hours (8mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "5527001",
            "description": "CONJUGATED OESTROGENS EQUINE & NORGESTREL tabs 625micrograms + 150micrograms",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "5527002",
            "description": "CONJUGATED OESTROGENS EQUINE & NORGESTREL tabs 1.25mg + 150micrograms",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "5747007",
            "description": "CONJUGATED OESTROGENS 625/NORGESTREL 500 MCG TAB",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "5837001",
            "description": "ESTRADIOL VALERATE & (ESTRADIOL VALERATE + NORGESTREL) tabs 2mg + (2mg + 500micrograms)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "5838001",
            "description": "ESTRADIOL & (ESTRADIOL + NORETHISTERONE) & (ESTRADIOL) triphasic tabs 2mg + (2mg + 1mg) + (1mg)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "5838002",
            "description": "ESTRADIOL & (ESTRADIOL + NORETHISTERONE) & (ESTRADIOL) triphasic forte tabs 4mg + (4mg + 1mg) + (1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "6235007",
            "description": "CONJUGATED OESTROGENS / NORGESTREL 1.25 MG TAB",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "6303001",
            "description": "ESTRADIOL VALERATE tabs 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "6303002",
            "description": "ESTRADIOL VALERATE tabs 2mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "6421001",
            "description": "ETHINYLESTRADIOL tabs 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "6680001",
            "description": "LIVIAL tabs 2.5mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "6684001",
            "description": "TIBOLONE tabs 2.5mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "6926001",
            "description": "EVOREL -50 patch 50mcg/24 hours (3.2mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "6926002",
            "description": "EVOREL -25 patch 25mcg/24 hours (1.6mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "6926003",
            "description": "EVOREL -75 patch 75micrograms/24 hours(4.8mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "7037001",
            "description": "ESTRADIOL TWICE WEEKLY patch 100mcg/24 hours (6.4mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "7037002",
            "description": "ESTRADIOL TWICE WEEKLY transdermal patch 80micrograms/24 hours",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "7037003",
            "description": "ESTRADIOL TWICE WEEKLY transdermal patch 40micrograms/24 hours",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "704001",
            "description": "OVESTIN tabs 250micrograms",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "704002",
            "description": "OVESTIN tabs 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "7317001",
            "description": "MESTRANOL + NORETHISTERONE tabs",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "7413001",
            "description": "EVOREL PAK treatment pack 50mcg/24hours(3.2mg/unit) + 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "7414001",
            "description": "ESTRADIOL + NORETHISTERONE patch+tab 50mcg/24hours(3.2mg/unit) + 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "7559001",
            "description": "NUVELLE CONTINUOUS tabs 2mg + 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "7628001",
            "description": "ESTRADIOL TWICE WEEKLY patch 50micrograms/24 hours (4mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "7633001",
            "description": "PROGYNOVA TS 100 patch 100mcg/24 hour (7.6mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "7748001",
            "description": "ESTRADIOL + (ESTRADIOL + NORETHISTERONE ACETATE) tabs 1mg + (1mg + 1mg)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "7778001",
            "description": "PROGYNOVA TS 25 patch 25micrograms/24 hours (2mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "779001",
            "description": "PREMARIN tabs 625micrograms",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "779002",
            "description": "PREMARIN tabs 1.25mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "779003",
            "description": "PREMARIN tabs 2.5mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "780001",
            "description": "PREMPAK 0.625 tabs",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "7828001",
            "description": "ESTRADIOL & (ESTRADIOL + DYDROGESTERONE) tabs 1mg + 5mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "7934001",
            "description": "EVOREL -100 patch 100mcg/24 hours (6.4mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8123001",
            "description": "ESTRADIOL VALERATE + NORETHISTERONE (continuous combined) tabs 1mg + 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8124001",
            "description": "ESTRADIOL VALERATE + NORETHISTERONE (continuous combined) tabs 2mg + 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8125001",
            "description": "ESTRADIOL + NORETHISTERONE ACETATE (continuous combined) tabs 1mg + 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8128001",
            "description": "ESTRADIOL VALERATE + NORGESTREL tabs 2mg + 500micrograms",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8129001",
            "description": "ESTRADIOL VALERATE + LEVONORGESTREL tabs 1mg + 250micrograms",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8130001",
            "description": "ESTRADIOL VALERATE + LEVONORGESTREL tabs 2mg + 75micrograms",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8133001",
            "description": "ESTRADIOL VALERATE + MEDROXYPROGESTERONE ACETATE tabs 2mg + 20mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8134001",
            "description": "FEMTAB tabs 2mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8135001",
            "description": "FEMTAB SEQUI tabs",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8137001",
            "description": "FEMTAB CONTINUOUS tabs 2mg + 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8140001",
            "description": "FEMTAB tabs 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8319001",
            "description": "ESTRADIOL + NORETHISTERONE ACETATE patch+tab 50mcg/24hours(4mg/unit) + 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8379001",
            "description": "MENOREST patch 37.5micrograms/24 hours (3.29mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8379002",
            "description": "MENOREST patch 50micrograms/24 hours (4.33mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8379003",
            "description": "MENOREST patch 75micrograms/24hours (6.57mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8439001",
            "description": "PRO-JUVEN crm 1.5%",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8453001",
            "description": "ESTRADIOL & (ESTRADIOL + NORETHISTERONE) tabs 2mg + (2mg + 1mg)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8520001",
            "description": "ESTRADIOL VALERATE & (ESTRADIOL VALERATE + MEDROXYPROGESTERONE ACETATE) + PLACEBO tabs 2mg + (2mg + ",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8530001",
            "description": "ESTRADIOL & (ESTRADIOL + LEVONORGESTREL) ONCE WEEKLY patch 50mcg/24hrs + (50mcg+10mcg/24hrs)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8542001",
            "description": "FEMATRIX 80 patch 80mcg/24 hours (2.5mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8576001",
            "description": "KLIOFEM tabs 2mg + 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8587001",
            "description": "ESTRADIOL + NORETHISTERONE ACETATE (continuous combined) tabs 2mg + 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8587002",
            "description": "ESTRADIOL + NORETHISTERONE ACETATE (continuous combined) tabs 2mg + 0.7mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8587003",
            "description": "ESTRADIOL + NORETHISTERONE ACETATE (continuous combined) tabs 1mg + 0.5mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8599001",
            "description": "OESTROGEL gel 0.06%",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8600001",
            "description": "ESTRADIOL gel 0.06%",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8600002",
            "description": "ESTRADIOL gel 0.1%",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8610001",
            "description": "FEMOSTON tabs 1mg + 10mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8610002",
            "description": "FEMOSTON tabs 2mg + 10mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8610003",
            "description": "FEMOSTON tabs 2mg + 20mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8611001",
            "description": "ESTRADIOL & (ESTRADIOL + DYDROGESTERONE) tabs 1mg + (1mg + 10mg)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8611002",
            "description": "ESTRADIOL & (ESTRADIOL + DYDROGESTERONE) tabs 2mg + (2mg + 10 mg)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8611003",
            "description": "ESTRADIOL & (ESTRADIOL + DYDROGESTERONE) tabs 2mg + (2mg + 20mg)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8621001",
            "description": "EVISTA FC tab 60mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8648001",
            "description": "TRIDESTRA tabs",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8649001",
            "description": "ESTRADIOL VALERATE + MEDROXYPROGESTERONE ACETATE tabs",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8649002",
            "description": "ESTRADIOL VALERATE + MEDROXYPROGESTERONE ACETATE tabs 1mg + 5mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8649003",
            "description": "ESTRADIOL VALERATE + MEDROXYPROGESTERONE ACETATE tabs 1mg + 2.5mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8671001",
            "description": "ADGYN COMBI tabs 2mg + (2mg + 1mg)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8692001",
            "description": "ESTRADIOL & DYDROGESTERONE patch+tab 80mcg/24 hours + 10mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8692002",
            "description": "ESTRADIOL & DYDROGESTERONE patch+tab 40mcg/24 hours + 10mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8732001",
            "description": "ETHINYLESTRADIOL + METHYLTESTOSTERONE tabs 4.4micrograms + 3.6mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8885001",
            "description": "PREMIQUE tabs 625micrograms + 5mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8886001",
            "description": "CONJUGATED OESTROGENS EQUINE + MEDROXYPROGESTERONE ACETATE (continuous combined) tabs 625micrograms ",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8902001",
            "description": "PREMIQUE CYCLE tabs",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8903001",
            "description": "CONJUGAT OESTROGE EQUI & (CONJUGAT OESTROGE EQUI + MEDROXYPROGESTERO ACETAT tab 625 micrograms + (62",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8909001",
            "description": "ESTRADIOL TWICE WEEKLY patch 37.5micrograms/24 hours (3.29mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8909002",
            "description": "ESTRADIOL TWICE WEEKLY patch 50micrograms/24 hours (4.33mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8909003",
            "description": "ESTRADIOL TWICE WEEKLY patch 75micrograms/24hours (6.57mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8913001",
            "description": "ESTRADIOL + (ESTRADIOL + NORETHISTERONE ACETATE) tabs 2mg + (2mg + 1 mg)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8945001",
            "description": "FEMATRIX 40 patch 40micrograms/24 hours (1.25mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "8947001",
            "description": "FEMAPAK 80 treatment pack 80mcg/24 hours + 10mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9105001",
            "description": "FEMSEVEN 50 patch 50micrograms/24 hours(1.5mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9124001",
            "description": "ELLESTE-SOLO tabs 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9124002",
            "description": "ELLESTE-SOLO tabs 2mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9126001",
            "description": "ELLESTE-DUET tabs 2mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9126002",
            "description": "ELLESTE-DUET tabs 1mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9164001",
            "description": "ESTRADIOL ONCE WEEKLY patch 50micrograms/24 hours(1.5mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9164002",
            "description": "ESTRADIOL ONCE WEEKLY patch 50mcg/24hours (3.8 mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9164003",
            "description": "ESTRADIOL ONCE WEEKLY patch 100mcg/24 hour (7.6mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9165001",
            "description": "ESTRADIOL ONCE WEEKLY transdermal patch 75micrograms/24 hours",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9165002",
            "description": "ESTRADIOL ONCE WEEKLY patch 100mcg/24 hours (3.0mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9165003",
            "description": "ESTRADIOL ONCE WEEKLY transdermal patch 25micrograms/24 hours",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9180001",
            "description": "PROGYNOVA TS patch 50mcg/24hours (3.8 mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9180002",
            "description": "PROGYNOVA TS forte patch 100mcg/24 hour (7.6mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9186001",
            "description": "ESTRADIOL ACETATE vaginal ring 50micrograms/24 hours(12.4mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9228001",
            "description": "IMPROVERA tabs 1.5mg + 10mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9229001",
            "description": "PIPERAZINE OESTRONE SULPHATE + MEDROXYPROGESTERONE tabs 1.5mg + 10mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9353001",
            "description": "ESTRADIOL + LEVONORGESTREL - ONCE WEEKLY patch 50micrograms+7micrograms/24 hours",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9354001",
            "description": "FEMSEVEN CONTI patch",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9379001",
            "description": "FEMAPAK 40 treatment pack 40mcg/24 hours + 10mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9381001",
            "description": "INDIVINA tabs 1mg + 5mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9381002",
            "description": "INDIVINA tabs 1mg + 2.5mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9381003",
            "description": "INDIVINA tabs 2mg + 5mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9382001",
            "description": "ESTRADIOL VALERATE + MEDROXYPROGESTERONE ACETATE tabs 2mg + 5mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9476001",
            "description": "CLIMESSE tabs 2mg + 0.7mg",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9752001",
            "description": "ESTRADIOL TWICE WEEKLY patch 25micrograms/24 hours (0.75mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9752002",
            "description": "ESTRADIOL TWICE WEEKLY patch 50micrograms/24 hours(1.5mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9752003",
            "description": "ESTRADIOL TWICE WEEKLY patch 100micrograms/24hrs (3.0mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9758001",
            "description": "ESTRADERM MX patch 25micrograms/24 hours (0.75mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9758002",
            "description": "ESTRADERM MX patch 50micrograms/24 hours(1.5mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9758003",
            "description": "ESTRADERM MX patch 100micrograms/24hrs (3.0mg/unit)",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          },
          {
            "code": "9916001",
            "description": "ESTRADIOL + NORETHISTERONE ACETATE - TWICE WEEKLY patch (50mcg + 170mcg)/24 hr",
            "attributes": {
              "Entity type": "hormone replacement drugs",
              "Category": "drug",
              "Coding System (GPRD_product_code)": "GPRD_product_code"
            }
          }
        ]
      }
    ],
    "status": 2,
    "doi": "https://doi.org/10.48533/m6zb-5a74",
    "is_deleted": null,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 1,
      "name": "Clinical-Coded Phenotype",
      "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 840,
        "version_name": "Hormone Replacement Drugs",
        "version_date": "2021-10-06T16:18:46.606153Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]