[
  {
    "phenotype_id": "PH4202",
    "phenotype_version_id": 9420,
    "name": "Hodgkin Lymphoma",
    "definition": "A viral infectious disease that results in destruction of immune system, leading to life\\-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre\\-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles.\n\nUKB baseline self reported fields.\n",
    "implementation": "The earliest record across all sources is obtained.\n",
    "publications": [
      {
        "doi": "https://doi.org/10.1038/s41598-025-05838-9",
        "details": "Torralbo, Ana and Davitte, Jonathan M. and Croteau-Chonka, Damien C. and Ytsma, Cai R. and Tomlinson, Christopher and Fitzpatrick, Natalie and Chung, Sheng-Chia and Fatemifar, Ghazaleh and Cortes, Adrian S. and Richardson, Tom G. and Barclay, Matthew and Carrasco Zanini Sanchez, Julia and Finan, Chris and Hemingway, Harry and Hingorani, Aroon D. and Kuan Po Ai, Valerie and Langenberg, Claudia and Lyratzopoulos, Georgios and Lumbers, Tom and Pietzner, Maik and Shah, Anoop Dinesh and Thygesen, Johan Hilge and Zelenka, Natalie and Whittaker, John C. and Ehm, Margaret G. and Denaxas, Spiros, A Computational Framework for Defining and Validating Reproducible Phenotyping Algorithms of 313 Diseases in the UK Biobank.",
        "primary": true
      }
    ],
    "validation": "Phenotypes underwent a multi\\-layered validation approach that included a) evaluating data source concordance, b) age\\-sex incidence and baseline prevalence patterns, c) an external comparison to a representative and unselected UK EHR dataset, d) modifiable risk factor associations, and e) genetic correlations with external genome\\-wide association studies (GWAS). Results showed consistent disease distributions by age and sex, high ranked correlation with general population prevalence estimates, confirmed risk factor associations, and significant genetic correlations with external GWAS.\n",
    "citation_requirements": null,
    "created": "2026-06-08T20:11:15.033529Z",
    "author": "Torralbo, A; Davitte, J M; Croteau-Chonka, D C; Ytsma, C; Tomlinson, C; Fitzpatrick, N K; Chung, S C; Fatemifar, G; Cortes, A S; Richardson, T G; Barclay, M; Carrasco Zanini, J; Finan, C; Hemingway, H; Hingorani, A; Kuan, V; Langenberg, C; Lyratzopoulos, G; Lumbers, R T; Pietzner, M; Shah, A D; Thygesen, J H; Zelenka, N; Whittaker, J C; Ehm, M G; Denaxas, S",
    "collections": [
      {
        "name": "Phenotype Library",
        "value": 18
      },
      {
        "name": "UK Biobank",
        "value": 32
      }
    ],
    "tags": null,
    "organisation": null,
    "world_access": 1,
    "updated": "2026-06-08T20:11:15.027010Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Disease or syndrome",
        "value": "2"
      }
    ],
    "trials": null,
    "ontology": null,
    "phenoflowid": null,
    "data_sources": [
      {
        "name": "UK Biobank",
        "value": 13,
        "uid": "6a9f93ad-2434-41d9-93bf-6e9d2eee04e5",
        "url": "https://healthdatagateway.org/en/dataset/700",
        "datasource_id": 700
      },
      {
        "name": "Patient Episode Dataset for Wales (PEDW)",
        "value": 40,
        "uid": "4c33a5d2-164c-41d7-9797-dc2b008cc852",
        "url": "https://healthdatagateway.org/en/dataset/318",
        "datasource_id": 318
      },
      {
        "name": "Scottish Cancer Registry (SMR06)",
        "value": 417,
        "uid": "ad36dc03-1856-44de-99b0-1af6f312d86b",
        "url": "https://healthdatagateway.org/en/dataset/79",
        "datasource_id": 79
      },
      {
        "name": "Cancer Registration Data",
        "value": 788,
        "uid": "6904a2ff-ab44-4dd6-b9ec-25d3cad29e43",
        "url": "https://healthdatagateway.org/en/dataset/880",
        "datasource_id": 880
      }
    ],
    "endorsements": null,
    "project_name": null,
    "coding_system": [
      {
        "name": "UKBioBank codes",
        "value": 12
      },
      {
        "name": "ICD10 codes",
        "value": 4
      },
      {
        "name": "Read codes v3",
        "value": 6
      }
    ],
    "corresp_author": "Ana Torralbo",
    "event_date_range": null,
    "concept_information": [
      {
        "concept_id": 10262,
        "concept_version_id": 17747,
        "concept_name": "Cancer code, self-reported",
        "coding_system": {
          "id": 12,
          "name": "UKBioBank codes",
          "description": "UKBioBank codes"
        },
        "phenotype_id": "PH4202",
        "phenotype_version_id": 9420,
        "phenotype_name": "Hodgkin Lymphoma",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "1052",
            "description": "hodgkins lymphoma / hodgkins disease",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10263,
        "concept_version_id": 17748,
        "concept_name": "Diagnoses - main ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4202",
        "phenotype_version_id": 9420,
        "phenotype_name": "Hodgkin Lymphoma",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "C81",
            "description": "Hodgkin lymphoma",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10264,
        "concept_version_id": 17749,
        "concept_name": "Diagnoses - secondary ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4202",
        "phenotype_version_id": 9420,
        "phenotype_name": "Hodgkin Lymphoma",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "C81",
            "description": "Hodgkin lymphoma",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10265,
        "concept_version_id": 17750,
        "concept_name": "Underlying (primary) cause of death: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4202",
        "phenotype_version_id": 9420,
        "phenotype_name": "Hodgkin Lymphoma",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "C81",
            "description": "Hodgkin lymphoma",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10266,
        "concept_version_id": 17751,
        "concept_name": "Contributory (secondary) causes of death: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4202",
        "phenotype_version_id": 9420,
        "phenotype_name": "Hodgkin Lymphoma",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "C81",
            "description": "Hodgkin lymphoma",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10267,
        "concept_version_id": 17752,
        "concept_name": "GP clinical event records",
        "coding_system": {
          "id": 6,
          "name": "Read codes v3",
          "description": "Read codes v3"
        },
        "phenotype_id": "PH4202",
        "phenotype_version_id": 9420,
        "phenotype_name": "Hodgkin Lymphoma",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "B61..00",
            "description": "Hodgkin's disease",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B610.00",
            "description": "Hodgkin's paragranuloma",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B610100",
            "description": "Hodgkin's paragranuloma of lymph nodes of head, face, neck",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B610300",
            "description": "Hodgkin's paragranuloma of intra-abdominal lymph nodes",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B611.00",
            "description": "Hodgkin's granuloma",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B61..11",
            "description": "Hodgkin lymphoma",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B611100",
            "description": "Hodgkin's granuloma of lymph nodes of head, face and neck",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B612.00",
            "description": "Hodgkin's sarcoma",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B612400",
            "description": "Hodgkin's sarcoma of lymph nodes of axilla and upper limb",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B613.",
            "description": "Lymphocyte-rich classical Hodgkin lymphoma",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B613.00",
            "description": "Hodgkin's disease, lymphocytic-histiocytic predominance",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B613000",
            "description": "Hodgkin's, lymphocytic-histiocytic predominance unspec site",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B613100",
            "description": "Hodgkin's, lymphocytic-histiocytic pred of head, face, neck",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B613200",
            "description": "Hodgkin's, lymphocytic-histiocytic pred intrathoracic nodes",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B613300",
            "description": "Hodgkin's, lymphocytic-histiocytic pred intra-abdominal node",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B613500",
            "description": "Hodgkin's, lymphocytic-histiocytic pred inguinal and leg",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B613600",
            "description": "Hodgkin's, lymphocytic-histiocytic pred intrapelvic nodes",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B613700",
            "description": "Hodgkin's, lymphocytic-histiocytic predominance of spleen",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B613800",
            "description": "Hodgkin's, lymphocytic-histiocytic pred of multiple sites",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B613z00",
            "description": "Hodgkin's, lymphocytic-histiocytic predominance NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B614.00",
            "description": "Hodgkin's disease, nodular sclerosis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B614000",
            "description": "Hodgkin's disease, nodular sclerosis of unspecified site",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B614100",
            "description": "Hodgkin's nodular sclerosis of head, face and neck",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B614200",
            "description": "Hodgkin's nodular sclerosis of intrathoracic lymph nodes",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B614300",
            "description": "Hodgkin's nodular sclerosis of intra-abdominal lymph nodes",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B614400",
            "description": "Hodgkin's nodular sclerosis of lymph nodes of axilla and arm",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B614700",
            "description": "Hodgkin's disease, nodular sclerosis of spleen",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B614800",
            "description": "Hodgkin's nodular sclerosis of lymph nodes of multiple sites",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B614z00",
            "description": "Hodgkin's disease, nodular sclerosis NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B615.00",
            "description": "Hodgkin's disease, mixed cellularity",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B615000",
            "description": "Hodgkin's disease, mixed cellularity of unspecified site",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B615100",
            "description": "Hodgkin's mixed cellularity of lymph nodes head, face, neck",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B615200",
            "description": "Hodgkin's mixed cellularity of intrathoracic lymph nodes",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B615500",
            "description": "Hodgkin's mixed cellularity of lymph nodes inguinal and leg",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B615z00",
            "description": "Hodgkin's disease, mixed cellularity NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B616.00",
            "description": "Hodgkin's disease, lymphocytic depletion",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B616000",
            "description": "Hodgkin's lymphocytic depletion of unspecified site",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B616400",
            "description": "Hodgkin's lymphocytic depletion lymph nodes axilla and arm",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B616500",
            "description": "Hodgkin's lymphocytic depletion lymph nodes inguinal and leg",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B616700",
            "description": "Hodgkin's disease, lymphocytic depletion of spleen",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B616800",
            "description": "Hodgkin's lymphocytic depletion lymph nodes multiple sites",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B616z00",
            "description": "Hodgkin's disease, lymphocytic depletion NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B617.00",
            "description": "Nodular lymphocyte predominant Hodgkin lymphoma",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B618.00",
            "description": "Nodular sclerosis classical Hodgkin lymphoma",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B619.00",
            "description": "Mixed cellularity classical Hodgkin lymphoma",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B61B.00",
            "description": "Lymphocyte-rich classical Hodgkin lymphoma",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B61C.00",
            "description": "Other classical Hodgkin lymphoma",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B61z.",
            "description": "Hodgkin's disease NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B61z.00",
            "description": "Hodgkin's disease NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B61z000",
            "description": "Hodgkin's disease NOS, unspecified site",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B61z100",
            "description": "Hodgkin's disease NOS of lymph nodes of head, face and neck",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B61z.11",
            "description": "Hodgkin lymphoma NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B61z200",
            "description": "Hodgkin's disease NOS of intrathoracic lymph nodes",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B61z300",
            "description": "Hodgkin's disease NOS of intra-abdominal lymph nodes",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B61z400",
            "description": "Hodgkin's disease NOS of lymph nodes of axilla and arm",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B61z500",
            "description": "Hodgkin's disease NOS of lymph nodes inguinal region and leg",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B61z700",
            "description": "Hodgkin's disease NOS of spleen",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B61z800",
            "description": "Hodgkin's disease NOS of lymph nodes of multiple sites",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B61zz00",
            "description": "Hodgkin's disease NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "BBj..00",
            "description": "[M]Hodgkin's disease",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "BBj0.00",
            "description": "[M]Hodgkin's disease NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "BBj1.00",
            "description": "[M]Hodgkin's disease, lymphocytic predominance",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "BBj1000",
            "description": "[M]Hodgkin,s disease, lymphocytic predominance, diffuse",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "BBj1100",
            "description": "[M]Hodgkin,s disease, lymphocytic predominance, nodular",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "BBj2.00",
            "description": "[M]Hodgkin's disease, mixed cellularity",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "BBj4.00",
            "description": "[M]Hodgkin's disease,lymphocytic depletion,diffuse fibrosis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "BBj6.00",
            "description": "[M]Hodgkin's disease, nodular sclerosis NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "BBj6000",
            "description": "[M]Hodgkin,s disease, nodular sclerosis, lymphocytic predom",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "BBj6100",
            "description": "[M]Hodgkin,s disease, nodular sclerosis, mixed cellularity",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "BBj6200",
            "description": "[M]Hodgkin,s disease, nodular sclerosis, lymphocytic deplet",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "BBj7.00",
            "description": "[M]Hodgkin's disease, nodular sclerosis, cellular phase",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "BBj9.00",
            "description": "[M]Hodgkin's granuloma",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "BBjz.00",
            "description": "[M]Hodgkin's disease NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "ByuD000",
            "description": "[X]Other Hodgkin's disease",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XaC2n",
            "description": "[M]Hodgkin's disease NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "ZV10711",
            "description": "[V]Personal history of Hodgkin's disease",
            "attributes": {
              "type": "prevalent"
            }
          }
        ]
      },
      {
        "concept_id": 10268,
        "concept_version_id": 17753,
        "concept_name": "Type of cancer: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4202",
        "phenotype_version_id": 9420,
        "phenotype_name": "Hodgkin Lymphoma",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "C81",
            "description": "Hodgkin lymphoma",
            "attributes": {
              "type": "any"
            }
          }
        ]
      }
    ],
    "status": 1,
    "doi": "https://doi.org/10.48533/pnec-9j74",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 2,
      "name": "BHF Data Science Centre Phenotype",
      "description": "BHF Data Science Centre Phenotype definitions that describe a list of clinical codes, algorithms using clinical codes, or set of clinical trials. Visit the BHF Data Science Centre website to learn more: https://bhfdatasciencecentre.org",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 9420,
        "version_name": "Hodgkin Lymphoma",
        "version_date": "2026-06-08T20:11:15.043049Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]