[
  {
    "phenotype_id": "PH4219",
    "phenotype_version_id": 9437,
    "name": "Juvenile arthritis",
    "definition": "Juvenile arthritis (JA), also known as pediatric rheumatic disease, isn't a specific disease. It's an umbrella term to describe the inflammatory and rheumatic diseases that develop in children under the age of 16\\.\n\nUKB baseline self reported fields.\n",
    "implementation": "The earliest record across all sources is obtained.\n",
    "publications": [
      {
        "doi": "https://doi.org/10.1038/s41598-025-05838-9",
        "details": "Torralbo, Ana and Davitte, Jonathan M. and Croteau-Chonka, Damien C. and Ytsma, Cai R. and Tomlinson, Christopher and Fitzpatrick, Natalie and Chung, Sheng-Chia and Fatemifar, Ghazaleh and Cortes, Adrian S. and Richardson, Tom G. and Barclay, Matthew and Carrasco Zanini Sanchez, Julia and Finan, Chris and Hemingway, Harry and Hingorani, Aroon D. and Kuan Po Ai, Valerie and Langenberg, Claudia and Lyratzopoulos, Georgios and Lumbers, Tom and Pietzner, Maik and Shah, Anoop Dinesh and Thygesen, Johan Hilge and Zelenka, Natalie and Whittaker, John C. and Ehm, Margaret G. and Denaxas, Spiros, A Computational Framework for Defining and Validating Reproducible Phenotyping Algorithms of 313 Diseases in the UK Biobank.",
        "primary": true
      }
    ],
    "validation": "Phenotypes underwent a multi\\-layered validation approach that included a) evaluating data source concordance, b) age\\-sex incidence and baseline prevalence patterns, c) an external comparison to a representative and unselected UK EHR dataset, d) modifiable risk factor associations, and e) genetic correlations with external genome\\-wide association studies (GWAS). Results showed consistent disease distributions by age and sex, high ranked correlation with general population prevalence estimates, confirmed risk factor associations, and significant genetic correlations with external GWAS.\n",
    "citation_requirements": null,
    "created": "2026-06-08T20:12:06.647075Z",
    "author": "Torralbo, A; Davitte, J M; Croteau-Chonka, D C; Ytsma, C; Tomlinson, C; Fitzpatrick, N K; Chung, S C; Fatemifar, G; Cortes, A S; Richardson, T G; Barclay, M; Carrasco Zanini, J; Finan, C; Hemingway, H; Hingorani, A; Kuan, V; Langenberg, C; Lyratzopoulos, G; Lumbers, R T; Pietzner, M; Shah, A D; Thygesen, J H; Zelenka, N; Whittaker, J C; Ehm, M G; Denaxas, S",
    "collections": [
      {
        "name": "Phenotype Library",
        "value": 18
      },
      {
        "name": "UK Biobank",
        "value": 32
      }
    ],
    "tags": null,
    "organisation": null,
    "world_access": 1,
    "updated": "2026-06-08T20:12:06.640673Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Disease or syndrome",
        "value": "2"
      }
    ],
    "trials": null,
    "ontology": null,
    "phenoflowid": null,
    "data_sources": [
      {
        "name": "UK Biobank",
        "value": 13,
        "uid": "6a9f93ad-2434-41d9-93bf-6e9d2eee04e5",
        "url": "https://healthdatagateway.org/en/dataset/700",
        "datasource_id": 700
      },
      {
        "name": "Patient Episode Dataset for Wales (PEDW)",
        "value": 40,
        "uid": "4c33a5d2-164c-41d7-9797-dc2b008cc852",
        "url": "https://healthdatagateway.org/en/dataset/318",
        "datasource_id": 318
      },
      {
        "name": "Scottish Cancer Registry (SMR06)",
        "value": 417,
        "uid": "ad36dc03-1856-44de-99b0-1af6f312d86b",
        "url": "https://healthdatagateway.org/en/dataset/79",
        "datasource_id": 79
      },
      {
        "name": "Cancer Registration Data",
        "value": 788,
        "uid": "6904a2ff-ab44-4dd6-b9ec-25d3cad29e43",
        "url": "https://healthdatagateway.org/en/dataset/880",
        "datasource_id": 880
      }
    ],
    "endorsements": null,
    "project_name": null,
    "coding_system": [
      {
        "name": "ICD10 codes",
        "value": 4
      },
      {
        "name": "Read codes v3",
        "value": 6
      }
    ],
    "corresp_author": "Ana Torralbo",
    "event_date_range": null,
    "concept_information": [
      {
        "concept_id": 10360,
        "concept_version_id": 17845,
        "concept_name": "Diagnoses - main ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4219",
        "phenotype_version_id": 9437,
        "phenotype_name": "Juvenile arthritis",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "M08",
            "description": "Juvenile arthritis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "M09",
            "description": "Juvenile arthritis in diseases classified elsewhere",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10361,
        "concept_version_id": 17846,
        "concept_name": "Diagnoses - secondary ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4219",
        "phenotype_version_id": 9437,
        "phenotype_name": "Juvenile arthritis",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "M08",
            "description": "Juvenile arthritis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "M09",
            "description": "Juvenile arthritis in diseases classified elsewhere",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10362,
        "concept_version_id": 17847,
        "concept_name": "Underlying (primary) cause of death: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4219",
        "phenotype_version_id": 9437,
        "phenotype_name": "Juvenile arthritis",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "M08",
            "description": "Juvenile arthritis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "M09",
            "description": "Juvenile arthritis in diseases classified elsewhere",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10363,
        "concept_version_id": 17848,
        "concept_name": "Contributory (secondary) causes of death: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4219",
        "phenotype_version_id": 9437,
        "phenotype_name": "Juvenile arthritis",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "M08",
            "description": "Juvenile arthritis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "M09",
            "description": "Juvenile arthritis in diseases classified elsewhere",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10364,
        "concept_version_id": 17849,
        "concept_name": "GP clinical event records",
        "coding_system": {
          "id": 6,
          "name": "Read codes v3",
          "description": "Read codes v3"
        },
        "phenotype_id": "PH4219",
        "phenotype_version_id": 9437,
        "phenotype_name": "Juvenile arthritis",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "N043.00",
            "description": "Juvenile rheumatoid arthritis - Still's disease",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N043000",
            "description": "Juvenile rheumatoid arthropathy unspecified",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N043100",
            "description": "Acute polyarticular juvenile rheumatoid arthritis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N0432",
            "description": "Pauciarticular onset juvenile chronic arthritis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N043200",
            "description": "Pauciarticular juvenile rheumatoid arthritis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N043300",
            "description": "Monarticular juvenile rheumatoid arthritis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N043z00",
            "description": "Juvenile rheumatoid arthritis NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N045.00",
            "description": "Other juvenile arthritis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N045000",
            "description": "Juvenile ankylosing spondylitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N045100",
            "description": "Juvenile seronegative polyarthritis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N045200",
            "description": "Juvenile arthritis in psoriasis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N045300",
            "description": "Juvenile arthritis in Crohn's disease",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N045400",
            "description": "Juvenile arthritis in ulcerative colitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N045500",
            "description": "Juvenile rheumatoid arthritis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "N045600",
            "description": "Pauciarticular onset juvenile chronic arthritis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Nyu1500",
            "description": "[X]Other juvenile arthritis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "X701t",
            "description": "Juvenile rheumatoid arthritis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "X701x",
            "description": "Juvenile ankylosing spondylitis",
            "attributes": {
              "type": "any"
            }
          }
        ]
      }
    ],
    "status": 1,
    "doi": "https://doi.org/10.48533/fe4j-ns92",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 2,
      "name": "BHF Data Science Centre Phenotype",
      "description": "BHF Data Science Centre Phenotype definitions that describe a list of clinical codes, algorithms using clinical codes, or set of clinical trials. Visit the BHF Data Science Centre website to learn more: https://bhfdatasciencecentre.org",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 9437,
        "version_name": "Juvenile arthritis",
        "version_date": "2026-06-08T20:12:06.658911Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]