[
  {
    "phenotype_id": "PH4222",
    "phenotype_version_id": 9440,
    "name": "Slow fetal growth or low birth weight",
    "definition": "A condition where the baby is smaller than expected or when a baby's growth slows or stops during pregnancy.\n\nUKB baseline self reported fields.\n",
    "implementation": "The earliest record across all sources is obtained.\n",
    "publications": [
      {
        "doi": "https://doi.org/10.1038/s41598-025-05838-9",
        "details": "Torralbo, Ana and Davitte, Jonathan M. and Croteau-Chonka, Damien C. and Ytsma, Cai R. and Tomlinson, Christopher and Fitzpatrick, Natalie and Chung, Sheng-Chia and Fatemifar, Ghazaleh and Cortes, Adrian S. and Richardson, Tom G. and Barclay, Matthew and Carrasco Zanini Sanchez, Julia and Finan, Chris and Hemingway, Harry and Hingorani, Aroon D. and Kuan Po Ai, Valerie and Langenberg, Claudia and Lyratzopoulos, Georgios and Lumbers, Tom and Pietzner, Maik and Shah, Anoop Dinesh and Thygesen, Johan Hilge and Zelenka, Natalie and Whittaker, John C. and Ehm, Margaret G. and Denaxas, Spiros, A Computational Framework for Defining and Validating Reproducible Phenotyping Algorithms of 313 Diseases in the UK Biobank.",
        "primary": true
      }
    ],
    "validation": "Phenotypes underwent a multi\\-layered validation approach that included a) evaluating data source concordance, b) age\\-sex incidence and baseline prevalence patterns, c) an external comparison to a representative and unselected UK EHR dataset, d) modifiable risk factor associations, and e) genetic correlations with external genome\\-wide association studies (GWAS). Results showed consistent disease distributions by age and sex, high ranked correlation with general population prevalence estimates, confirmed risk factor associations, and significant genetic correlations with external GWAS.\n",
    "citation_requirements": null,
    "created": "2026-06-08T20:12:14.988303Z",
    "author": "Torralbo, A; Davitte, J M; Croteau-Chonka, D C; Ytsma, C; Tomlinson, C; Fitzpatrick, N K; Chung, S C; Fatemifar, G; Cortes, A S; Richardson, T G; Barclay, M; Carrasco Zanini, J; Finan, C; Hemingway, H; Hingorani, A; Kuan, V; Langenberg, C; Lyratzopoulos, G; Lumbers, R T; Pietzner, M; Shah, A D; Thygesen, J H; Zelenka, N; Whittaker, J C; Ehm, M G; Denaxas, S",
    "collections": [
      {
        "name": "Phenotype Library",
        "value": 18
      },
      {
        "name": "UK Biobank",
        "value": 32
      }
    ],
    "tags": null,
    "organisation": null,
    "world_access": 1,
    "updated": "2026-06-08T20:12:14.982139Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Disease or syndrome",
        "value": "2"
      }
    ],
    "trials": null,
    "ontology": [
      {
        "name": "Disorder due to slow fetal growth, low and/or high birth weight (disorder)",
        "value": 724258
      }
    ],
    "phenoflowid": null,
    "data_sources": [
      {
        "name": "UK Biobank",
        "value": 13,
        "uid": "6a9f93ad-2434-41d9-93bf-6e9d2eee04e5",
        "url": "https://healthdatagateway.org/en/dataset/700",
        "datasource_id": 700
      },
      {
        "name": "Patient Episode Dataset for Wales (PEDW)",
        "value": 40,
        "uid": "4c33a5d2-164c-41d7-9797-dc2b008cc852",
        "url": "https://healthdatagateway.org/en/dataset/318",
        "datasource_id": 318
      },
      {
        "name": "Scottish Cancer Registry (SMR06)",
        "value": 417,
        "uid": "ad36dc03-1856-44de-99b0-1af6f312d86b",
        "url": "https://healthdatagateway.org/en/dataset/79",
        "datasource_id": 79
      },
      {
        "name": "Cancer Registration Data",
        "value": 788,
        "uid": "6904a2ff-ab44-4dd6-b9ec-25d3cad29e43",
        "url": "https://healthdatagateway.org/en/dataset/880",
        "datasource_id": 880
      }
    ],
    "endorsements": null,
    "project_name": null,
    "coding_system": [
      {
        "name": "ICD10 codes",
        "value": 4
      },
      {
        "name": "Read codes v3",
        "value": 6
      }
    ],
    "corresp_author": "Ana Torralbo",
    "event_date_range": null,
    "concept_information": [
      {
        "concept_id": 10375,
        "concept_version_id": 17860,
        "concept_name": "Diagnoses - main ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4222",
        "phenotype_version_id": 9440,
        "phenotype_name": "Slow fetal growth or low birth weight",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "P05.0",
            "description": "Light for gestational age",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "P05.1",
            "description": "Small for gestational age",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "P05.9",
            "description": "Slow fetal growth, unspecified",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "P07.0",
            "description": "Extremely low birth weight",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "P07.1",
            "description": "Other low birth weight",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10376,
        "concept_version_id": 17861,
        "concept_name": "Diagnoses - secondary ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4222",
        "phenotype_version_id": 9440,
        "phenotype_name": "Slow fetal growth or low birth weight",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "P05.0",
            "description": "Light for gestational age",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "P05.1",
            "description": "Small for gestational age",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "P05.9",
            "description": "Slow fetal growth, unspecified",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "P07.0",
            "description": "Extremely low birth weight",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "P07.1",
            "description": "Other low birth weight",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10377,
        "concept_version_id": 17862,
        "concept_name": "Underlying (primary) cause of death: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4222",
        "phenotype_version_id": 9440,
        "phenotype_name": "Slow fetal growth or low birth weight",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "P05.0",
            "description": "Light for gestational age",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "P05.1",
            "description": "Small for gestational age",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "P05.9",
            "description": "Slow fetal growth, unspecified",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "P07.0",
            "description": "Extremely low birth weight",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "P07.1",
            "description": "Other low birth weight",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10378,
        "concept_version_id": 17863,
        "concept_name": "Contributory (secondary) causes of death: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4222",
        "phenotype_version_id": 9440,
        "phenotype_name": "Slow fetal growth or low birth weight",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "P05.0",
            "description": "Light for gestational age",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "P05.1",
            "description": "Small for gestational age",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "P05.9",
            "description": "Slow fetal growth, unspecified",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "P07.0",
            "description": "Extremely low birth weight",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "P07.1",
            "description": "Other low birth weight",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10379,
        "concept_version_id": 17864,
        "concept_name": "GP clinical event records",
        "coding_system": {
          "id": 6,
          "name": "Read codes v3",
          "description": "Read codes v3"
        },
        "phenotype_id": "PH4222",
        "phenotype_version_id": 9440,
        "phenotype_name": "Slow fetal growth or low birth weight",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "L265.00",
            "description": "Small-for-dates fetus in pregnancy",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "L265000",
            "description": "Small-for-dates unspecified",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "L265100",
            "description": "Small-for-dates - delivered",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "L265200",
            "description": "Small-for-dates with antenatal problem",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "L265z00",
            "description": "Small-for-dates NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Q10..00",
            "description": "Slow fetal growth and fetal malnutrition",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Q100.00",
            "description": "Fetus small-for-dates, without mention of malnutrition",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Q100.11",
            "description": "Fetus small-for-dates (SFD), without mention of malnutrition",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Q101.00",
            "description": "Fetus small-for-dates with signs of malnutrition",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Q101.11",
            "description": "Fetus small-for-dates (SFD) with signs of malnutrition",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Q10z.00",
            "description": "Fetal growth retardation NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Q10z.11",
            "description": "Intrauterine growth retardation",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Q11..00",
            "description": "Short gestation and unspecified low birthweight problems",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Q110.00",
            "description": "Very premature - less than 1000g or less than 28 weeks",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Q111.00",
            "description": "Premature - weight 1000g-2499g or gestation of 28-37weeks",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Q113.00",
            "description": "Light for gestational age",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Q114.00",
            "description": "Low birthweight",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Q114000",
            "description": "Birth weight 1000-2499 g",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Q115.00",
            "description": "Extremely low birth weight infant",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Q115000",
            "description": "Birth weight 999 g or less",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Q13..00",
            "description": "Light for gestational age",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Qyu1000",
            "description": "[X]Other low birth weight",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Xa09Y",
            "description": "Extremely low birth weight infant",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XaCMT",
            "description": "Birth weight 1000-2499 g",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XaCMU",
            "description": "Birth weight 999 g or less",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XE1eU",
            "description": "Slow fetal growth and fetal malnutrition",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XE1eV",
            "description": "Fetal growth retardation NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XE1eX",
            "description": "Very premature - less than 1000g or less than 28 weeks",
            "attributes": {
              "type": "any"
            }
          }
        ]
      }
    ],
    "status": 1,
    "doi": "https://doi.org/10.48533/wvdc-6969",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 2,
      "name": "BHF Data Science Centre Phenotype",
      "description": "BHF Data Science Centre Phenotype definitions that describe a list of clinical codes, algorithms using clinical codes, or set of clinical trials. Visit the BHF Data Science Centre website to learn more: https://bhfdatasciencecentre.org",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 9440,
        "version_name": "Slow fetal growth or low birth weight",
        "version_date": "2026-06-08T20:12:14.996750Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]