[
  {
    "phenotype_id": "PH4225",
    "phenotype_version_id": 9443,
    "name": "Lichen planus",
    "definition": "A lichen disease that is located in skin, located in tongue or located in oral mucosa, which presents itself in the form of papules, lesions or rashes. The cause is not known.\n\nUKB baseline self reported fields.\n",
    "implementation": "The earliest record across all sources is obtained.\n",
    "publications": [
      {
        "doi": "https://doi.org/10.1038/s41598-025-05838-9",
        "details": "Torralbo, Ana and Davitte, Jonathan M. and Croteau-Chonka, Damien C. and Ytsma, Cai R. and Tomlinson, Christopher and Fitzpatrick, Natalie and Chung, Sheng-Chia and Fatemifar, Ghazaleh and Cortes, Adrian S. and Richardson, Tom G. and Barclay, Matthew and Carrasco Zanini Sanchez, Julia and Finan, Chris and Hemingway, Harry and Hingorani, Aroon D. and Kuan Po Ai, Valerie and Langenberg, Claudia and Lyratzopoulos, Georgios and Lumbers, Tom and Pietzner, Maik and Shah, Anoop Dinesh and Thygesen, Johan Hilge and Zelenka, Natalie and Whittaker, John C. and Ehm, Margaret G. and Denaxas, Spiros, A Computational Framework for Defining and Validating Reproducible Phenotyping Algorithms of 313 Diseases in the UK Biobank.",
        "primary": true
      }
    ],
    "validation": "Phenotypes underwent a multi\\-layered validation approach that included a) evaluating data source concordance, b) age\\-sex incidence and baseline prevalence patterns, c) an external comparison to a representative and unselected UK EHR dataset, d) modifiable risk factor associations, and e) genetic correlations with external genome\\-wide association studies (GWAS). Results showed consistent disease distributions by age and sex, high ranked correlation with general population prevalence estimates, confirmed risk factor associations, and significant genetic correlations with external GWAS.\n",
    "citation_requirements": null,
    "created": "2026-06-08T20:12:24.286996Z",
    "author": "Torralbo, A; Davitte, J M; Croteau-Chonka, D C; Ytsma, C; Tomlinson, C; Fitzpatrick, N K; Chung, S C; Fatemifar, G; Cortes, A S; Richardson, T G; Barclay, M; Carrasco Zanini, J; Finan, C; Hemingway, H; Hingorani, A; Kuan, V; Langenberg, C; Lyratzopoulos, G; Lumbers, R T; Pietzner, M; Shah, A D; Thygesen, J H; Zelenka, N; Whittaker, J C; Ehm, M G; Denaxas, S",
    "collections": [
      {
        "name": "Phenotype Library",
        "value": 18
      },
      {
        "name": "UK Biobank",
        "value": 32
      }
    ],
    "tags": null,
    "organisation": null,
    "world_access": 1,
    "updated": "2026-06-08T20:12:24.281114Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Disease or syndrome",
        "value": "2"
      }
    ],
    "trials": null,
    "ontology": [
      {
        "name": "Lichen planus (disorder)",
        "value": 360962
      }
    ],
    "phenoflowid": null,
    "data_sources": [
      {
        "name": "UK Biobank",
        "value": 13,
        "uid": "6a9f93ad-2434-41d9-93bf-6e9d2eee04e5",
        "url": "https://healthdatagateway.org/en/dataset/700",
        "datasource_id": 700
      },
      {
        "name": "Patient Episode Dataset for Wales (PEDW)",
        "value": 40,
        "uid": "4c33a5d2-164c-41d7-9797-dc2b008cc852",
        "url": "https://healthdatagateway.org/en/dataset/318",
        "datasource_id": 318
      },
      {
        "name": "Scottish Cancer Registry (SMR06)",
        "value": 417,
        "uid": "ad36dc03-1856-44de-99b0-1af6f312d86b",
        "url": "https://healthdatagateway.org/en/dataset/79",
        "datasource_id": 79
      },
      {
        "name": "Cancer Registration Data",
        "value": 788,
        "uid": "6904a2ff-ab44-4dd6-b9ec-25d3cad29e43",
        "url": "https://healthdatagateway.org/en/dataset/880",
        "datasource_id": 880
      }
    ],
    "endorsements": null,
    "project_name": null,
    "coding_system": [
      {
        "name": "UKBioBank codes",
        "value": 12
      },
      {
        "name": "ICD10 codes",
        "value": 4
      },
      {
        "name": "Read codes v3",
        "value": 6
      }
    ],
    "corresp_author": "Ana Torralbo",
    "event_date_range": null,
    "concept_information": [
      {
        "concept_id": 10394,
        "concept_version_id": 17879,
        "concept_name": "Non-cancer illness code, self-reported",
        "coding_system": {
          "id": 12,
          "name": "UKBioBank codes",
          "description": "UKBioBank codes"
        },
        "phenotype_id": "PH4225",
        "phenotype_version_id": 9443,
        "phenotype_name": "Lichen planus",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "1549",
            "description": "lichen planus",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10395,
        "concept_version_id": 17880,
        "concept_name": "Diagnoses - main ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4225",
        "phenotype_version_id": 9443,
        "phenotype_name": "Lichen planus",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "L43",
            "description": "Lichen planus",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "L66.1",
            "description": "Lichen planopilaris",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10396,
        "concept_version_id": 17881,
        "concept_name": "Diagnoses - secondary ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4225",
        "phenotype_version_id": 9443,
        "phenotype_name": "Lichen planus",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "L43",
            "description": "Lichen planus",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "L66.1",
            "description": "Lichen planopilaris",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10397,
        "concept_version_id": 17882,
        "concept_name": "Underlying (primary) cause of death: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4225",
        "phenotype_version_id": 9443,
        "phenotype_name": "Lichen planus",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "L43",
            "description": "Lichen planus",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "L66.1",
            "description": "Lichen planopilaris",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10398,
        "concept_version_id": 17883,
        "concept_name": "Contributory (secondary) causes of death: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4225",
        "phenotype_version_id": 9443,
        "phenotype_name": "Lichen planus",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "L43",
            "description": "Lichen planus",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "L66.1",
            "description": "Lichen planopilaris",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10399,
        "concept_version_id": 17884,
        "concept_name": "GP clinical event records",
        "coding_system": {
          "id": 6,
          "name": "Read codes v3",
          "description": "Read codes v3"
        },
        "phenotype_id": "PH4225",
        "phenotype_version_id": 9443,
        "phenotype_name": "Lichen planus",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "M170.00",
            "description": "Lichen planus",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "M170000",
            "description": "Lichen planus actinicus",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "M170100",
            "description": "Lichen planus annularis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "M170200",
            "description": "Lichen planus atrophicus",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "M170300",
            "description": "Lichen planus bullosus",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "M170400",
            "description": "Lichen planus hypertrophicus",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "M170500",
            "description": "Lichen planus linearis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "M170700",
            "description": "Lichen planus obtusus",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "M170800",
            "description": "Subacute active lichen planus",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "M170900",
            "description": "Follicular lichen planus",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "M170z00",
            "description": "Lichen planus NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "M240R00",
            "description": "Lichen planopilaris",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Myu3200",
            "description": "[X]Other lichen planus",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "X507b",
            "description": "Follicular lichen planus",
            "attributes": {
              "type": "any"
            }
          }
        ]
      }
    ],
    "status": 1,
    "doi": "https://doi.org/10.48533/z181-xa50",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 2,
      "name": "BHF Data Science Centre Phenotype",
      "description": "BHF Data Science Centre Phenotype definitions that describe a list of clinical codes, algorithms using clinical codes, or set of clinical trials. Visit the BHF Data Science Centre website to learn more: https://bhfdatasciencecentre.org",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 9443,
        "version_name": "Lichen planus",
        "version_date": "2026-06-08T20:12:24.297772Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]