[ { "phenotype_id": "PH430", "phenotype_version_id": 860, "name": "Osteoporosis", "definition": "Patient level data were extracted from the General Practice Research Database (GPRD), which contains anonymised, patient based data on morbidity, prescribing, treatment, and referral collected from over 500 general practices, covering about 7% of the UK population (4.4 million patients).14 Data are in Read code format—a hierarchical system used to code clinical data. Additional data on prescriptions and test results are available as free-text entries. We selected a sample of 148 practices that provided data to the GPRD continuously between January 2000 and December 2007, structured to include a range of list (patient panel) sizes. Selected practices were nationally representative in terms of patient sex and age distribution and area socioeconomic deprivation but had a relatively large average list size, reflecting a bias towards larger practices in the GPRD. Overall, the selected practices performed marginally better than national practices on the clinical indicators in the Quality and Outcomes Framework. A random selection of 4500 patients registered for at least one day between 1 January 2000 and 31 December 2007 was drawn from each practice. For practices with fewer than 4501 patients, all patients were selected. The final sample consisted of 653 500 patients. Patients with relevant conditions were identified from their diagnostic Read codes. Patients for whom targets were met were identified from the relevant Read codes and free-text terms.\n\n\n\n\n\n\n\n\n", "implementation": "", "publications": [ { "doi": null, "details": "Tim Doran, Evangelos Kontopantelis, Jose M Valderas, Stephen Campbell, Martin Roland, Chris Salisbury, David Reeves, Effect of financial incentives on incentivised and non-incentivised clinical activities: longitudinal analysis of data from the UK Quality and Outcomes Framework. BMJ, 342:d3590, 2011." } ], "validation": "", "citation_requirements": "", "created": "2021-10-06T16:19:03.891566Z", "author": "Tim Doran, Evangelos Kontopantelis, Jose M Valderas, Stephen Campbell, Martin Roland, Chris Salisbury, David Reeves", "collections": [ { "name": "ClinicalCodes Repository", "value": 25 }, { "name": "Phenotype Library", "value": 18 } ], "tags": null, "organisation": null, "world_access": 1, "updated": "2021-10-06T16:19:03.891593Z", "sex": [ { "name": "Both", "value": "3" } ], "type": [ { "name": "Disease or syndrome", "value": "2" } ], "ontology": null, "phenoflowid": "", "data_sources": [ { "name": "CPRD GOLD", "value": 5, "uid": "a29feafa-7bdd-44e9-b977-c9d26425e67f", "url": "https://healthdatagateway.org/en/dataset/694", "datasource_id": 694 } ], "coding_system": [ { "name": "Read codes v2", "value": 5 } ], "event_date_range": "01/01/2000 - 31/12/2007", "concept_information": [ { "concept_id": 1783, "concept_version_id": 4704, "concept_name": "Osteoporosis - Primary Care", "coding_system": { "id": 5, "name": "Read codes v2", "description": "Read codes v2" }, "phenotype_id": "PH430", "phenotype_version_id": 860, "phenotype_name": "Osteoporosis", "code_attribute_header": [ "Entity type", "Category", "Coding System (Read)" ], "codes": [ { "code": "585O.00", "description": "Quantitative ultrasound scan of heel - result osteoporotic", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "58E4.00", "description": "Forearm DXA scan result osteoporotic", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "58EA.00", "description": "Heel DXA scan result osteoporotic", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "58EG.00", "description": "Hip DXA scan result osteoporotic", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "58EM.00", "description": "Lumbar DXA scan result osteoporotic", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "66a..00", "description": "Osteoporosis monitoring", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "66a2.00", "description": "Osteoporosis treatment started", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "66a3.00", "description": "Osteoporosis treatment stopped", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "66a4.00", "description": "Osteoporosis treatment changed", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "66a6.00", "description": "Osteoporosis - dietary advice", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "66a7.00", "description": "Osteoporosis - dietary assessment", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "66a8.00", "description": "Osteoporosis - exercise advice", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "66a9.00", "description": "Osteoporosis - falls prevention", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "66aA.00", "description": "Osteoporosis - treatment response", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "66aE.00", "description": "Refer to osteoporosis specialist", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "7230A", "description": "OSTEOPOROSIS", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "7230B", "description": "OSTEOPOROSIS SENILIS", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "7230D", "description": "VERTEBRAL OSTEOPOROSIS", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "7230PM", "description": "OSTEOPOROSIS POSTMENOPAUSAL", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "7230PT", "description": "OSTEOPOROSIS POST-TRAUMATIC", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "8HTS.00", "description": "Referral to osteoporosis clinic", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "9N0h.00", "description": "Seen in osteoporosis clinic", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "9Od0.00", "description": "Attends osteoporosis monitoring", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N330.00", "description": "Osteoporosis", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N330000", "description": "Osteoporosis; unspecified", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N330100", "description": "Senile osteoporosis", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N330200", "description": "Postmenopausal osteoporosis", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N330300", "description": "Idiopathic osteoporosis", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N330400", "description": "Dissuse osteoporosis", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N330500", "description": "Drug-induced osteoporosis", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N330600", "description": "Postoophorectomy osteoporosis", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N330700", "description": "Postsurgical malabsorption osteoporosis", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N330800", "description": "Localized osteoporosis - Lequesne", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N330900", "description": "Osteoporosis in multiple myelomatosis", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N330A00", "description": "Osteoporosis in endocrine disorders", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N330B00", "description": "Vertebral osteoporosis", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N330C00", "description": "Osteoporosis localized to spine", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N330D00", "description": "Osteoporosis due to corticosteroids", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N330z00", "description": "Osteoporosis NOS", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N331.14", "description": "Osteoporotic vertebral collapse", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N331200", "description": "Postoophorectomy osteoporosis with pathological fracture", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N331300", "description": "Osteoporosis of disuse with pathological fracture", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N331400", "description": "Postsurgical malabsorption osteoporosis with path fracture", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N331500", "description": "Drug-induced osteoporosis with pathological fracture", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N331600", "description": "Idiopathic osteoporosis with pathological fracture", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N331800", "description": "Osteoporosis + pathological fracture lumbar vertebrae", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N331900", "description": "Osteoporosis + pathological fracture thoracic vertebrae", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N331A00", "description": "Osteoporosis + pathological fracture cervical vertebrae", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N331B00", "description": "Postmenopausal osteoporosis with pathological fracture", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N331H00", "description": "Collapse of cervical vertebra due to osteoporosis", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N331J00", "description": "Collapse of lumbar vertebra due to osteoporosis", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N331K00", "description": "Collapse of thoracic vertebra due to osteoporosis", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N331L00", "description": "Collapse of vertebra due to osteoporosis NOS", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N331M00", "description": "Fragility fracture due to unspecified osteoporosis", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N374600", "description": "Osteoporotic kyphosis", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "NyuB000", "description": "[X]Other osteoporosis with pathological fracture", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "NyuB100", "description": "[X]Other osteoporosis", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "NyuB200", "description": "[X]Osteoporosis in other disorders classified elsewhere", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "NyuB800", "description": "[X]Unspecified osteoporosis with pathological fracture", "attributes": { "Entity type": "osteoporosis", "Category": "diagnostic", "Coding System (Read)": "Read" } } ] } ], "status": 2, "doi": "https://doi.org/10.48533/p2fp-0v75", "is_deleted": null, "publish_status": 2, "owner": "ieuan.scanlon", "template": { "id": 1, "name": "Clinical-Coded Phenotype", "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.", "version_id": 1 }, "versions": [ { "version_id": 860, "version_name": "Osteoporosis", "version_date": "2021-10-06T16:19:03.913447Z", "is_published": true, "is_latest": true } ] } ]