[
  {
    "phenotype_id": "PH4311",
    "phenotype_version_id": 9529,
    "name": "Primary Malignancy_Stomach",
    "definition": "A benign or malignant neoplasm involving the stomach.\n\nUKB baseline self reported fields.\n",
    "implementation": "The earliest record across all sources is obtained.\n",
    "publications": [
      {
        "doi": "https://doi.org/10.1038/s41598-025-05838-9",
        "details": "Torralbo, Ana and Davitte, Jonathan M. and Croteau-Chonka, Damien C. and Ytsma, Cai R. and Tomlinson, Christopher and Fitzpatrick, Natalie and Chung, Sheng-Chia and Fatemifar, Ghazaleh and Cortes, Adrian S. and Richardson, Tom G. and Barclay, Matthew and Carrasco Zanini Sanchez, Julia and Finan, Chris and Hemingway, Harry and Hingorani, Aroon D. and Kuan Po Ai, Valerie and Langenberg, Claudia and Lyratzopoulos, Georgios and Lumbers, Tom and Pietzner, Maik and Shah, Anoop Dinesh and Thygesen, Johan Hilge and Zelenka, Natalie and Whittaker, John C. and Ehm, Margaret G. and Denaxas, Spiros, A Computational Framework for Defining and Validating Reproducible Phenotyping Algorithms of 313 Diseases in the UK Biobank.",
        "primary": true
      }
    ],
    "validation": "Phenotypes underwent a multi\\-layered validation approach that included a) evaluating data source concordance, b) age\\-sex incidence and baseline prevalence patterns, c) an external comparison to a representative and unselected UK EHR dataset, d) modifiable risk factor associations, and e) genetic correlations with external genome\\-wide association studies (GWAS). Results showed consistent disease distributions by age and sex, high ranked correlation with general population prevalence estimates, confirmed risk factor associations, and significant genetic correlations with external GWAS.\n",
    "citation_requirements": null,
    "created": "2026-06-08T20:17:01.890978Z",
    "author": "Torralbo, A; Davitte, J M; Croteau-Chonka, D C; Ytsma, C; Tomlinson, C; Fitzpatrick, N K; Chung, S C; Fatemifar, G; Cortes, A S; Richardson, T G; Barclay, M; Carrasco Zanini, J; Finan, C; Hemingway, H; Hingorani, A; Kuan, V; Langenberg, C; Lyratzopoulos, G; Lumbers, R T; Pietzner, M; Shah, A D; Thygesen, J H; Zelenka, N; Whittaker, J C; Ehm, M G; Denaxas, S",
    "collections": [
      {
        "name": "Phenotype Library",
        "value": 18
      },
      {
        "name": "UK Biobank",
        "value": 32
      }
    ],
    "tags": null,
    "organisation": null,
    "world_access": 1,
    "updated": "2026-06-08T20:17:01.885242Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Disease or syndrome",
        "value": "2"
      }
    ],
    "trials": null,
    "ontology": [
      {
        "name": "Malignant tumor of stomach (disorder)",
        "value": 28057
      }
    ],
    "phenoflowid": null,
    "data_sources": [
      {
        "name": "UK Biobank",
        "value": 13,
        "uid": "6a9f93ad-2434-41d9-93bf-6e9d2eee04e5",
        "url": "https://healthdatagateway.org/en/dataset/700",
        "datasource_id": 700
      },
      {
        "name": "Patient Episode Dataset for Wales (PEDW)",
        "value": 40,
        "uid": "4c33a5d2-164c-41d7-9797-dc2b008cc852",
        "url": "https://healthdatagateway.org/en/dataset/318",
        "datasource_id": 318
      },
      {
        "name": "Scottish Cancer Registry (SMR06)",
        "value": 417,
        "uid": "ad36dc03-1856-44de-99b0-1af6f312d86b",
        "url": "https://healthdatagateway.org/en/dataset/79",
        "datasource_id": 79
      },
      {
        "name": "Cancer Registration Data",
        "value": 788,
        "uid": "6904a2ff-ab44-4dd6-b9ec-25d3cad29e43",
        "url": "https://healthdatagateway.org/en/dataset/880",
        "datasource_id": 880
      }
    ],
    "endorsements": null,
    "project_name": null,
    "coding_system": [
      {
        "name": "UKBioBank codes",
        "value": 12
      },
      {
        "name": "ICD10 codes",
        "value": 4
      },
      {
        "name": "Read codes v3",
        "value": 6
      }
    ],
    "corresp_author": "Ana Torralbo",
    "event_date_range": null,
    "concept_information": [
      {
        "concept_id": 10921,
        "concept_version_id": 18406,
        "concept_name": "Cancer code, self-reported",
        "coding_system": {
          "id": 12,
          "name": "UKBioBank codes",
          "description": "UKBioBank codes"
        },
        "phenotype_id": "PH4311",
        "phenotype_version_id": 9529,
        "phenotype_name": "Primary Malignancy_Stomach",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "1018",
            "description": "stomach cancer",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10922,
        "concept_version_id": 18407,
        "concept_name": "Diagnoses - main ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4311",
        "phenotype_version_id": 9529,
        "phenotype_name": "Primary Malignancy_Stomach",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "C16",
            "description": "Malignant neoplasm of stomach",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10923,
        "concept_version_id": 18408,
        "concept_name": "Diagnoses - secondary ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4311",
        "phenotype_version_id": 9529,
        "phenotype_name": "Primary Malignancy_Stomach",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "C16",
            "description": "Malignant neoplasm of stomach",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10924,
        "concept_version_id": 18409,
        "concept_name": "Underlying (primary) cause of death: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4311",
        "phenotype_version_id": 9529,
        "phenotype_name": "Primary Malignancy_Stomach",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "C16",
            "description": "Malignant neoplasm of stomach",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10925,
        "concept_version_id": 18410,
        "concept_name": "Contributory (secondary) causes of death: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4311",
        "phenotype_version_id": 9529,
        "phenotype_name": "Primary Malignancy_Stomach",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "C16",
            "description": "Malignant neoplasm of stomach",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10926,
        "concept_version_id": 18411,
        "concept_name": "GP clinical event records",
        "coding_system": {
          "id": 6,
          "name": "Read codes v3",
          "description": "Read codes v3"
        },
        "phenotype_id": "PH4311",
        "phenotype_version_id": 9529,
        "phenotype_name": "Primary Malignancy_Stomach",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "B11..00",
            "description": "Malignant neoplasm of stomach",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B110.00",
            "description": "Malignant neoplasm of cardia of stomach",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B110000",
            "description": "Malignant neoplasm of cardiac orifice of stomach",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B110100",
            "description": "Malignant neoplasm of cardio-oesophageal junction of stomach",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B110111",
            "description": "Malignant neoplasm of gastro-oesophageal junction",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B110z00",
            "description": "Malignant neoplasm of cardia of stomach NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B111.00",
            "description": "Malignant neoplasm of pylorus of stomach",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B111000",
            "description": "Malignant neoplasm of prepylorus of stomach",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B111100",
            "description": "Malignant neoplasm of pyloric canal of stomach",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B111z00",
            "description": "Malignant neoplasm of pylorus of stomach NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B112.00",
            "description": "Malignant neoplasm of pyloric antrum of stomach",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B113.00",
            "description": "Malignant neoplasm of fundus of stomach",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B114.00",
            "description": "Malignant neoplasm of body of stomach",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B115.00",
            "description": "Malignant neoplasm of lesser curve of stomach unspecified",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B116.00",
            "description": "Malignant neoplasm of greater curve of stomach unspecified",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B117.00",
            "description": "Malignant neoplasm, overlapping lesion of stomach",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B118.00",
            "description": "Siewert type II adenocarcinoma",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B119.00",
            "description": "Siewert type III adenocarcinoma",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B11y.00",
            "description": "Malignant neoplasm of other specified site of stomach",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B11y000",
            "description": "Malignant neoplasm of anterior wall of stomach NEC",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B11y100",
            "description": "Malignant neoplasm of posterior wall of stomach NEC",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B11yz00",
            "description": "Malignant neoplasm of other specified site of stomach NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "B11z.00",
            "description": "Malignant neoplasm of stomach NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XaOqX",
            "description": "Siewert type II adenocarcinoma",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "XaOrB",
            "description": "Siewert type III adenocarcinoma",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "ZV10018",
            "description": "[V]Personal history of malignant neoplasm of stomach",
            "attributes": {
              "type": "prevalent"
            }
          }
        ]
      },
      {
        "concept_id": 10927,
        "concept_version_id": 18412,
        "concept_name": "Type of cancer: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4311",
        "phenotype_version_id": 9529,
        "phenotype_name": "Primary Malignancy_Stomach",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "C16",
            "description": "Malignant neoplasm of stomach",
            "attributes": {
              "type": "any"
            }
          }
        ]
      }
    ],
    "status": 1,
    "doi": "https://doi.org/10.48533/qfcp-6j09",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 2,
      "name": "BHF Data Science Centre Phenotype",
      "description": "BHF Data Science Centre Phenotype definitions that describe a list of clinical codes, algorithms using clinical codes, or set of clinical trials. Visit the BHF Data Science Centre website to learn more: https://bhfdatasciencecentre.org",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 9529,
        "version_name": "Primary Malignancy_Stomach",
        "version_date": "2026-06-08T20:17:01.900156Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]