[
  {
    "phenotype_id": "PH4321",
    "phenotype_version_id": 9539,
    "name": "Other interstitial pulmonary diseases with fibrosis",
    "definition": "Idiopathic pulmonary fibrosis (IPF) is a nonneoplastic pulmonary disease that is characterized by the formation of scar tissue within the lungs in the absence of any known cause.\n\nUKB baseline self reported fields.\n",
    "implementation": "The earliest record across all sources is obtained.\n",
    "publications": [
      {
        "doi": "https://doi.org/10.1038/s41598-025-05838-9",
        "details": "Torralbo, Ana and Davitte, Jonathan M. and Croteau-Chonka, Damien C. and Ytsma, Cai R. and Tomlinson, Christopher and Fitzpatrick, Natalie and Chung, Sheng-Chia and Fatemifar, Ghazaleh and Cortes, Adrian S. and Richardson, Tom G. and Barclay, Matthew and Carrasco Zanini Sanchez, Julia and Finan, Chris and Hemingway, Harry and Hingorani, Aroon D. and Kuan Po Ai, Valerie and Langenberg, Claudia and Lyratzopoulos, Georgios and Lumbers, Tom and Pietzner, Maik and Shah, Anoop Dinesh and Thygesen, Johan Hilge and Zelenka, Natalie and Whittaker, John C. and Ehm, Margaret G. and Denaxas, Spiros, A Computational Framework for Defining and Validating Reproducible Phenotyping Algorithms of 313 Diseases in the UK Biobank.",
        "primary": true
      }
    ],
    "validation": "Phenotypes underwent a multi\\-layered validation approach that included a) evaluating data source concordance, b) age\\-sex incidence and baseline prevalence patterns, c) an external comparison to a representative and unselected UK EHR dataset, d) modifiable risk factor associations, and e) genetic correlations with external genome\\-wide association studies (GWAS). Results showed consistent disease distributions by age and sex, high ranked correlation with general population prevalence estimates, confirmed risk factor associations, and significant genetic correlations with external GWAS.\n",
    "citation_requirements": null,
    "created": "2026-06-08T20:17:29.924641Z",
    "author": "Torralbo, A; Davitte, J M; Croteau-Chonka, D C; Ytsma, C; Tomlinson, C; Fitzpatrick, N K; Chung, S C; Fatemifar, G; Cortes, A S; Richardson, T G; Barclay, M; Carrasco Zanini, J; Finan, C; Hemingway, H; Hingorani, A; Kuan, V; Langenberg, C; Lyratzopoulos, G; Lumbers, R T; Pietzner, M; Shah, A D; Thygesen, J H; Zelenka, N; Whittaker, J C; Ehm, M G; Denaxas, S",
    "collections": [
      {
        "name": "Phenotype Library",
        "value": 18
      },
      {
        "name": "UK Biobank",
        "value": 32
      }
    ],
    "tags": null,
    "organisation": null,
    "world_access": 1,
    "updated": "2026-06-08T20:17:29.918947Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Disease or syndrome",
        "value": "2"
      }
    ],
    "trials": null,
    "ontology": [
      {
        "name": "Idiopathic pulmonary fibrosis (disorder)",
        "value": 265308
      }
    ],
    "phenoflowid": null,
    "data_sources": [
      {
        "name": "UK Biobank",
        "value": 13,
        "uid": "6a9f93ad-2434-41d9-93bf-6e9d2eee04e5",
        "url": "https://healthdatagateway.org/en/dataset/700",
        "datasource_id": 700
      },
      {
        "name": "Patient Episode Dataset for Wales (PEDW)",
        "value": 40,
        "uid": "4c33a5d2-164c-41d7-9797-dc2b008cc852",
        "url": "https://healthdatagateway.org/en/dataset/318",
        "datasource_id": 318
      },
      {
        "name": "Scottish Cancer Registry (SMR06)",
        "value": 417,
        "uid": "ad36dc03-1856-44de-99b0-1af6f312d86b",
        "url": "https://healthdatagateway.org/en/dataset/79",
        "datasource_id": 79
      },
      {
        "name": "Cancer Registration Data",
        "value": 788,
        "uid": "6904a2ff-ab44-4dd6-b9ec-25d3cad29e43",
        "url": "https://healthdatagateway.org/en/dataset/880",
        "datasource_id": 880
      }
    ],
    "endorsements": null,
    "project_name": null,
    "coding_system": [
      {
        "name": "ICD10 codes",
        "value": 4
      },
      {
        "name": "UKBioBank codes",
        "value": 12
      },
      {
        "name": "Non-standard codes",
        "value": 13
      },
      {
        "name": "Read codes v3",
        "value": 6
      }
    ],
    "corresp_author": "Ana Torralbo",
    "event_date_range": null,
    "concept_information": [
      {
        "concept_id": 10984,
        "concept_version_id": 18469,
        "concept_name": "Recent medication for idiopathic pulmonary fibrosis",
        "coding_system": {
          "id": 13,
          "name": "Non-standard codes",
          "description": "Non-standard codes"
        },
        "phenotype_id": "PH4321",
        "phenotype_version_id": 9539,
        "phenotype_name": "Other interstitial pulmonary diseases with fibrosis",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "1",
            "description": "Yes",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10985,
        "concept_version_id": 18470,
        "concept_name": "Doctor diagnosed idiopathic pulmonary fibrosis",
        "coding_system": {
          "id": 13,
          "name": "Non-standard codes",
          "description": "Non-standard codes"
        },
        "phenotype_id": "PH4321",
        "phenotype_version_id": 9539,
        "phenotype_name": "Other interstitial pulmonary diseases with fibrosis",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "1",
            "description": "Yes",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10986,
        "concept_version_id": 18471,
        "concept_name": "Non-cancer illness code, self-reported",
        "coding_system": {
          "id": 12,
          "name": "UKBioBank codes",
          "description": "UKBioBank codes"
        },
        "phenotype_id": "PH4321",
        "phenotype_version_id": 9539,
        "phenotype_name": "Other interstitial pulmonary diseases with fibrosis",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "1115",
            "description": "interstitial lung disease",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "1121",
            "description": "pulmonary fibrosis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "1122",
            "description": "fibrosing alveolitis/unspecified alveolitis",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10987,
        "concept_version_id": 18472,
        "concept_name": "Diagnoses - main ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4321",
        "phenotype_version_id": 9539,
        "phenotype_name": "Other interstitial pulmonary diseases with fibrosis",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "J84.1",
            "description": "Other interstitial pulmonary diseases with fibrosis",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10988,
        "concept_version_id": 18473,
        "concept_name": "Diagnoses - secondary ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4321",
        "phenotype_version_id": 9539,
        "phenotype_name": "Other interstitial pulmonary diseases with fibrosis",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "J84.1",
            "description": "Other interstitial pulmonary diseases with fibrosis",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10989,
        "concept_version_id": 18474,
        "concept_name": "Underlying (primary) cause of death: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4321",
        "phenotype_version_id": 9539,
        "phenotype_name": "Other interstitial pulmonary diseases with fibrosis",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "J84.1",
            "description": "Other interstitial pulmonary diseases with fibrosis",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10990,
        "concept_version_id": 18475,
        "concept_name": "Contributory (secondary) causes of death: ICD10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4321",
        "phenotype_version_id": 9539,
        "phenotype_name": "Other interstitial pulmonary diseases with fibrosis",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "J84.1",
            "description": "Other interstitial pulmonary diseases with fibrosis",
            "attributes": {
              "type": "any"
            }
          }
        ]
      },
      {
        "concept_id": 10991,
        "concept_version_id": 18476,
        "concept_name": "GP clinical event records",
        "coding_system": {
          "id": 6,
          "name": "Read codes v3",
          "description": "Read codes v3"
        },
        "phenotype_id": "PH4321",
        "phenotype_version_id": 9539,
        "phenotype_name": "Other interstitial pulmonary diseases with fibrosis",
        "code_attribute_header": [
          "type"
        ],
        "codes": [
          {
            "code": "23E5.00",
            "description": "O/E - fibrosis of lung present",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "23E5.11",
            "description": "O/E - fibrosis of lung",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H55..00",
            "description": "Postinflammatory pulmonary fibrosis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H55..11",
            "description": "Cirrhosis of lung",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H563.00",
            "description": "Idiopathic fibrosing alveolitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H563100",
            "description": "Diffuse pulmonary fibrosis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H563.11",
            "description": "Hamman - Rich syndrome",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H563.12",
            "description": "Cryptogenic fibrosing alveolitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H563.13",
            "description": "Idiopathic pulmonary fibrosis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H563200",
            "description": "Pulmonary fibrosis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H563300",
            "description": "Usual interstitial pneumonitis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "H563z00",
            "description": "Idiopathic fibrosing alveolitis NOS",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "Hyu5000",
            "description": "[X]Other interstitial pulmonary diseases with fibrosis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "X102u",
            "description": "Pulmonary fibrosis",
            "attributes": {
              "type": "any"
            }
          },
          {
            "code": "X102v",
            "description": "Usual interstitial pneumonitis",
            "attributes": {
              "type": "any"
            }
          }
        ]
      }
    ],
    "status": 1,
    "doi": "https://doi.org/10.48533/e321-1g27",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 2,
      "name": "BHF Data Science Centre Phenotype",
      "description": "BHF Data Science Centre Phenotype definitions that describe a list of clinical codes, algorithms using clinical codes, or set of clinical trials. Visit the BHF Data Science Centre website to learn more: https://bhfdatasciencecentre.org",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 9539,
        "version_name": "Other interstitial pulmonary diseases with fibrosis",
        "version_date": "2026-06-08T20:17:29.935485Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]