[ { "phenotype_id": "PH435", "phenotype_version_id": 870, "name": "Serious Mental Illness (SMI) Drugs", "definition": "Patient level data were extracted from the General Practice Research Database (GPRD), which contains anonymised, patient based data on morbidity, prescribing, treatment, and referral collected from over 500 general practices, covering about 7% of the UK population (4.4 million patients).14 Data are in Read code format—a hierarchical system used to code clinical data. Additional data on prescriptions and test results are available as free-text entries. We selected a sample of 148 practices that provided data to the GPRD continuously between January 2000 and December 2007, structured to include a range of list (patient panel) sizes. Selected practices were nationally representative in terms of patient sex and age distribution and area socioeconomic deprivation but had a relatively large average list size, reflecting a bias towards larger practices in the GPRD. Overall, the selected practices performed marginally better than national practices on the clinical indicators in the Quality and Outcomes Framework. A random selection of 4500 patients registered for at least one day between 1 January 2000 and 31 December 2007 was drawn from each practice. For practices with fewer than 4501 patients, all patients were selected. The final sample consisted of 653 500 patients. Patients with relevant conditions were identified from their diagnostic Read codes. Patients for whom targets were met were identified from the relevant Read codes and free-text terms.\n\n\n\n\n\n\n\n\n", "implementation": "", "publications": [ { "doi": null, "details": "Tim Doran, Evangelos Kontopantelis, Jose M Valderas, Stephen Campbell, Martin Roland, Chris Salisbury, David Reeves, Effect of financial incentives on incentivised and non-incentivised clinical activities: longitudinal analysis of data from the UK Quality and Outcomes Framework. BMJ, 342:d3590, 2011." } ], "validation": "", "citation_requirements": "", "created": "2021-10-06T16:19:12.753271Z", "author": "Tim Doran, Evangelos Kontopantelis, Jose M Valderas, Stephen Campbell, Martin Roland, Chris Salisbury, David Reeves", "collections": [ { "name": "ClinicalCodes Repository", "value": 25 }, { "name": "Phenotype Library", "value": 18 } ], "tags": null, "organisation": null, "world_access": 1, "updated": "2021-10-06T16:19:12.753298Z", "sex": [ { "name": "Both", "value": "3" } ], "type": [ { "name": "Drug", "value": "3" } ], "ontology": null, "phenoflowid": "", "data_sources": [ { "name": "CPRD GOLD", "value": 5, "uid": "a29feafa-7bdd-44e9-b977-c9d26425e67f", "url": "https://healthdatagateway.org/en/dataset/694", "datasource_id": 694 } ], "coding_system": [ { "name": "GPRD product codes", "value": 14 } ], "event_date_range": "01/01/2000 - 31/12/2007", "concept_information": [ { "concept_id": 1790, "concept_version_id": 4718, "concept_name": "Serious Mental Illness (SMI) Drugs - Primary Care", "coding_system": { "id": 14, "name": "GPRD product codes", "description": "GPRD product codes" }, "phenotype_id": "PH435", "phenotype_version_id": 870, "phenotype_name": "Serious Mental Illness (SMI) Drugs", "code_attribute_header": [ "Entity type", "Category", "Coding System (GPRD_product_code)" ], "codes": [ { "code": "1185001", "description": "CAMCOLIT 400 tabs", "attributes": { "Entity type": "SMI drugs", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "141001", "description": "CAMCOLIT 250 tabs", "attributes": { "Entity type": "SMI drugs", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "2020009", "description": "LITHIUM CARBONATE mr tab 400mg [APS]", "attributes": { "Entity type": "SMI drugs", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "2283001", "description": "LITHIUM CITRATE oral liq 1.018g/5ml", "attributes": { "Entity type": "SMI drugs", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "2294001", "description": "LI-LIQUID soln 509mg/5ml", "attributes": { "Entity type": "SMI drugs", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "2294002", "description": "LI-LIQUID soln 1.018g/5ml", "attributes": { "Entity type": "SMI drugs", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "2325007", "description": "LITHIUM 250 MG CAP", "attributes": { "Entity type": "SMI drugs", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "2465001", "description": "LITAREX CR tablets 564mg", "attributes": { "Entity type": "SMI drugs", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "3134007", "description": "LITHIUM 10.8 MMOLS/5MLS LIQ", "attributes": { "Entity type": "SMI drugs", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "3995001", "description": "LITHIUM CARBONATE mr tab 200mg", "attributes": { "Entity type": "SMI drugs", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "3995002", "description": "LITHIUM CARBONATE tabs 250mg", "attributes": { "Entity type": "SMI drugs", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "3995003", "description": "LITHIUM CARBONATE mr tab 300mg", "attributes": { "Entity type": "SMI drugs", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "3996001", "description": "LITHIUM CARBONATE mr tab 400mg", "attributes": { "Entity type": "SMI drugs", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "3997001", "description": "LITHIUM CARBONATE mr tab 450mg", "attributes": { "Entity type": "SMI drugs", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "3998001", "description": "PHASAL tabs 300mg", "attributes": { "Entity type": "SMI drugs", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "3999001", "description": "LITHIUM CITRATE mr tab 564mg", "attributes": { "Entity type": "SMI drugs", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "3999002", "description": "LITHIUM CITRATE sf liq 520mg/5ml", "attributes": { "Entity type": "SMI drugs", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "3999003", "description": "LITHIUM CITRATE oral liq 509mg/5ml", "attributes": { "Entity type": "SMI drugs", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "534001", "description": "LISKONUM tabs 450mg", "attributes": { "Entity type": "SMI drugs", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "6587001", "description": "PRIADEL liq 520mg/5ml", "attributes": { "Entity type": "SMI drugs", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "7457001", "description": "LITHONATE sr tab 400mg", "attributes": { "Entity type": "SMI drugs", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "782001", "description": "PRIADEL tabs 200mg", "attributes": { "Entity type": "SMI drugs", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } }, { "code": "782002", "description": "PRIADEL tabs 400mg", "attributes": { "Entity type": "SMI drugs", "Category": "drug", "Coding System (GPRD_product_code)": "GPRD_product_code" } } ] } ], "status": 2, "doi": "https://doi.org/10.48533/m54h-s331", "is_deleted": null, "publish_status": 2, "owner": "ieuan.scanlon", "template": { "id": 1, "name": "Clinical-Coded Phenotype", "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.", "version_id": 1 }, "versions": [ { "version_id": 870, "version_name": "Serious Mental Illness (SMI) Drugs", "version_date": "2021-10-06T16:19:12.775536Z", "is_published": true, "is_latest": true } ] } ]