[
  {
    "phenotype_id": "PH4443",
    "phenotype_version_id": 9956,
    "name": "CCU022_1 Breast cancer",
    "definition": "Phecode 174: Breast cancer\n",
    "implementation": "",
    "publications": [],
    "validation": "",
    "citation_requirements": "",
    "created": "2026-08-17T02:54:23.791039Z",
    "author": "Liu, H., Mizani, M. A., Zhao, Y., Wood, A., Inouye, M., Price, A. L., Jiang, X., on behalf of the CVD-COVID-UK/COVID-IMPACT Consortium",
    "collections": [
      {
        "name": "BHF Data Science Centre",
        "value": 20
      },
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": null,
    "world_access": 1,
    "updated": "2026-08-18T01:38:58.222980Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Disease or syndrome",
        "value": "2"
      }
    ],
    "trials": [],
    "ontology": null,
    "phenoflowid": "",
    "data_sources": null,
    "endorsements": [],
    "project_name": "",
    "coding_system": [
      {
        "name": "SNOMED  CT codes",
        "value": 9
      },
      {
        "name": "ICD10 codes",
        "value": 4
      }
    ],
    "corresp_author": "",
    "event_date_range": "",
    "concept_information": [
      {
        "concept_id": 11507,
        "concept_version_id": 18992,
        "concept_name": "ICD-10",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH4443",
        "phenotype_version_id": 9956,
        "phenotype_name": "CCU022_1 Breast cancer",
        "code_attribute_header": null,
        "codes": [
          {
            "code": "C50",
            "description": "Malignant neoplasm of breast",
            "attributes": null
          },
          {
            "code": "C500",
            "description": "Malignant neoplasm: Nipple and areola",
            "attributes": null
          },
          {
            "code": "C501",
            "description": "Malignant neoplasm: Central portion of breast",
            "attributes": null
          },
          {
            "code": "C502",
            "description": "Malignant neoplasm: Upper-inner quadrant of breast",
            "attributes": null
          },
          {
            "code": "C503",
            "description": "Malignant neoplasm: Lower-inner quadrant of breast",
            "attributes": null
          },
          {
            "code": "C504",
            "description": "Malignant neoplasm: Upper-outer quadrant of breast",
            "attributes": null
          },
          {
            "code": "C505",
            "description": "Malignant neoplasm: Lower-outer quadrant of breast",
            "attributes": null
          },
          {
            "code": "C506",
            "description": "Malignant neoplasm: Axillary tail of breast",
            "attributes": null
          },
          {
            "code": "C508",
            "description": "Malignant neoplasm: Overlapping lesion of breast",
            "attributes": null
          },
          {
            "code": "C509",
            "description": "Malignant neoplasm: Breast, unspecified",
            "attributes": null
          },
          {
            "code": "D05",
            "description": "Carcinoma in situ of breast",
            "attributes": null
          },
          {
            "code": "D051",
            "description": "Intraductal carcinoma in situ",
            "attributes": null
          },
          {
            "code": "D057",
            "description": "Other carcinoma in situ of breast",
            "attributes": null
          },
          {
            "code": "D059",
            "description": "Carcinoma in situ of breast, unspecified",
            "attributes": null
          },
          {
            "code": "D486",
            "description": "Neoplasm of uncertain or unknown behaviour: Breast",
            "attributes": null
          }
        ]
      },
      {
        "concept_id": 11508,
        "concept_version_id": 18993,
        "concept_name": "SNOMED",
        "coding_system": {
          "id": 9,
          "name": "SNOMED  CT codes",
          "description": "SNOMED CT codes"
        },
        "phenotype_id": "PH4443",
        "phenotype_version_id": 9956,
        "phenotype_name": "CCU022_1 Breast cancer",
        "code_attribute_header": null,
        "codes": [
          {
            "code": "1080091000119100",
            "description": "Infiltrating ductal carcinoma of axillary tail of left female breast (disorder)",
            "attributes": null
          },
          {
            "code": "1080111000119108",
            "description": "Infiltrating ductal carcinoma of central portion of left female breast (disorder)",
            "attributes": null
          },
          {
            "code": "1080121000119101",
            "description": "Infiltrating ductal carcinoma of lower inner quadrant of left female breast (disorder)",
            "attributes": null
          },
          {
            "code": "1080131000119103",
            "description": "Infiltrating ductal carcinoma of lower outer quadrant of left female breast (disorder)",
            "attributes": null
          },
          {
            "code": "1080151000119109",
            "description": "Infiltrating ductal carcinoma of upper inner quadrant of left female breast (disorder)",
            "attributes": null
          },
          {
            "code": "1080161000119106",
            "description": "Infiltrating ductal carcinoma of upper outer quadrant of left female breast (disorder)",
            "attributes": null
          },
          {
            "code": "1080171000119100",
            "description": "Infiltrating ductal carcinoma of axillary tail of right female breast (disorder)",
            "attributes": null
          },
          {
            "code": "1080191000119104",
            "description": "Infiltrating ductal carcinoma of central portion of right female breast (disorder)",
            "attributes": null
          },
          {
            "code": "1080201000119101",
            "description": "Infiltrating ductal carcinoma of lower inner quadrant of right female breast (disorder)",
            "attributes": null
          },
          {
            "code": "1080211000119103",
            "description": "Infiltrating ductal carcinoma of lower outer quadrant of right female breast (disorder)",
            "attributes": null
          },
          {
            "code": "1080231000119108",
            "description": "Infiltrating ductal carcinoma of upper inner quadrant of right female breast (disorder)",
            "attributes": null
          },
          {
            "code": "1080241000119104",
            "description": "Infiltrating ductal carcinoma of upper outer quadrant of right female breast (disorder)",
            "attributes": null
          },
          {
            "code": "1080261000119100",
            "description": "Infiltrating lobular carcinoma of left female breast (disorder)",
            "attributes": null
          },
          {
            "code": "1080341000119105",
            "description": "Infiltrating lobular carcinoma of right female breast (disorder)",
            "attributes": null
          },
          {
            "code": "1081551000119106",
            "description": "Recurrent primary malignant neoplasm of left female breast (disorder)",
            "attributes": null
          },
          {
            "code": "1081561000119108",
            "description": "Recurrent primary malignant neoplasm of right female breast (disorder)",
            "attributes": null
          },
          {
            "code": "1082701000112100",
            "description": "Locally advanced breast cancer (disorder)",
            "attributes": null
          },
          {
            "code": "1082901000112103",
            "description": "Primary malignant neoplasm of breast with axillary lymph node invasion (disorder)",
            "attributes": null
          },
          {
            "code": "109886000",
            "description": "Overlapping malignant neoplasm of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "109887009",
            "description": "Overlapping malignant neoplasm of male breast (disorder)",
            "attributes": null
          },
          {
            "code": "15635801000119106",
            "description": "Primary malignant neoplasm of bilateral female breasts (disorder)",
            "attributes": null
          },
          {
            "code": "188147009",
            "description": "Malignant neoplasm of nipple and areola of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "188151006",
            "description": "Malignant neoplasm of central part of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "188152004",
            "description": "Malignant neoplasm of upper-inner quadrant of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "188153009",
            "description": "Malignant neoplasm of lower-inner quadrant of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "188154003",
            "description": "Malignant neoplasm of upper-outer quadrant of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "188155002",
            "description": "Malignant neoplasm of lower-outer quadrant of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "188156001",
            "description": "Malignant neoplasm of axillary tail of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "188157005",
            "description": "Malignant neoplasm of overlapping sites of breast (disorder)",
            "attributes": null
          },
          {
            "code": "188159008",
            "description": "Malignant neoplasm of ectopic site of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "188163001",
            "description": "Malignant neoplasm of nipple and areola of male breast (disorder)",
            "attributes": null
          },
          {
            "code": "188168005",
            "description": "Malignant neoplasm of ectopic site of male breast (disorder)",
            "attributes": null
          },
          {
            "code": "254837009",
            "description": "Malignant neoplasm of breast (disorder)",
            "attributes": null
          },
          {
            "code": "254838004",
            "description": "Carcinoma of breast (disorder)",
            "attributes": null
          },
          {
            "code": "254839007",
            "description": "Scirrhous carcinoma of breast (disorder)",
            "attributes": null
          },
          {
            "code": "254840009",
            "description": "Inflammatory carcinoma of breast (disorder)",
            "attributes": null
          },
          {
            "code": "254841008",
            "description": "Cancer en cuirasse (disorder)",
            "attributes": null
          },
          {
            "code": "254843006",
            "description": "Familial cancer of breast (disorder)",
            "attributes": null
          },
          {
            "code": "254844000",
            "description": "Malignant phyllodes tumor of breast (disorder)",
            "attributes": null
          },
          {
            "code": "278050001",
            "description": "Sarcoma of breast (disorder)",
            "attributes": null
          },
          {
            "code": "278053004",
            "description": "Intraductal carcinoma of breast (disorder)",
            "attributes": null
          },
          {
            "code": "278054005",
            "description": "Lobular carcinoma of breast (disorder)",
            "attributes": null
          },
          {
            "code": "286893002",
            "description": "Carcinoma of breast - upper inner quadrant (disorder)",
            "attributes": null
          },
          {
            "code": "286894008",
            "description": "Carcinoma of breast - lower inner quadrant (disorder)",
            "attributes": null
          },
          {
            "code": "286895009",
            "description": "Carcinoma of breast - upper outer quadrant (disorder)",
            "attributes": null
          },
          {
            "code": "286896005",
            "description": "Carcinoma breast - lower outer quadrant (disorder)",
            "attributes": null
          },
          {
            "code": "286897001",
            "description": "Carcinoma of breast - axillary tail (disorder)",
            "attributes": null
          },
          {
            "code": "314955001",
            "description": "Local recurrence of malignant tumor of breast (disorder)",
            "attributes": null
          },
          {
            "code": "315004001",
            "description": "Metastasis from malignant tumor of breast (disorder)",
            "attributes": null
          },
          {
            "code": "353421000119109",
            "description": "Primary malignant neoplasm of axillary tail of left female breast (disorder)",
            "attributes": null
          },
          {
            "code": "353431000119107",
            "description": "Primary malignant neoplasm of female left breast (disorder)",
            "attributes": null
          },
          {
            "code": "353441000119103",
            "description": "Primary malignant neoplasm of central portion of female left breast (disorder)",
            "attributes": null
          },
          {
            "code": "353501000119104",
            "description": "Primary malignant neoplasm of axillary tail of right female breast (disorder)",
            "attributes": null
          },
          {
            "code": "353511000119101",
            "description": "Primary malignant neoplasm of female right breast (disorder)",
            "attributes": null
          },
          {
            "code": "353521000119108",
            "description": "Primary malignant neoplasm of central portion of female right breast (disorder)",
            "attributes": null
          },
          {
            "code": "354491000119109",
            "description": "Primary malignant neoplasm of left male breast (disorder)",
            "attributes": null
          },
          {
            "code": "354591000119108",
            "description": "Primary malignant neoplasm of right male breast (disorder)",
            "attributes": null
          },
          {
            "code": "372064008",
            "description": "Malignant neoplasm of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "372092003",
            "description": "Primary malignant neoplasm of axillary tail of breast (disorder)",
            "attributes": null
          },
          {
            "code": "372094002",
            "description": "Malignant neoplasm of axillary tail of breast (disorder)",
            "attributes": null
          },
          {
            "code": "372095001",
            "description": "Malignant neoplasm of male breast (disorder)",
            "attributes": null
          },
          {
            "code": "372096000",
            "description": "Carcinoma of male breast (disorder)",
            "attributes": null
          },
          {
            "code": "372137005",
            "description": "Primary malignant neoplasm of breast (disorder)",
            "attributes": null
          },
          {
            "code": "373080008",
            "description": "Malignant neoplasm of breast lower inner quadrant (disorder)",
            "attributes": null
          },
          {
            "code": "373081007",
            "description": "Malignant neoplasm of breast lower outer quadrant (disorder)",
            "attributes": null
          },
          {
            "code": "373082000",
            "description": "Malignant neoplasm of breast upper inner quadrant (disorder)",
            "attributes": null
          },
          {
            "code": "373083005",
            "description": "Malignant neoplasm of breast upper outer quadrant (disorder)",
            "attributes": null
          },
          {
            "code": "373088001",
            "description": "Primary malignant neoplasm of breast upper outer quadrant (disorder)",
            "attributes": null
          },
          {
            "code": "373089009",
            "description": "Primary malignant neoplasm of breast upper inner quadrant (disorder)",
            "attributes": null
          },
          {
            "code": "373090000",
            "description": "Primary malignant neoplasm of breast lower inner quadrant (disorder)",
            "attributes": null
          },
          {
            "code": "373091001",
            "description": "Primary malignant neoplasm of breast lower outer quadrant (disorder)",
            "attributes": null
          },
          {
            "code": "403458008",
            "description": "Localized skin involvement by breast carcinoma (disorder)",
            "attributes": null
          },
          {
            "code": "408643008",
            "description": "Infiltrating duct carcinoma of breast (disorder)",
            "attributes": null
          },
          {
            "code": "417181009",
            "description": "Hormone receptor positive malignant neoplasm of breast (disorder)",
            "attributes": null
          },
          {
            "code": "427685000",
            "description": "Human epidermal growth factor 2 positive carcinoma of breast (disorder)",
            "attributes": null
          },
          {
            "code": "431396003",
            "description": "Human epidermal growth factor 2 negative carcinoma of breast (disorder)",
            "attributes": null
          },
          {
            "code": "444604002",
            "description": "Carcinoma of breast with ductal and lobular features (disorder)",
            "attributes": null
          },
          {
            "code": "444712000",
            "description": "Mucinous carcinoma of breast (disorder)",
            "attributes": null
          },
          {
            "code": "447782002",
            "description": "Malignant epithelial neoplasm of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "447784001",
            "description": "Sarcoma of axillary tail of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "448257000",
            "description": "Sarcoma of male breast (disorder)",
            "attributes": null
          },
          {
            "code": "448388003",
            "description": "Sarcoma of lower outer quadrant of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "448408001",
            "description": "Sarcoma of upper inner quadrant of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "448435005",
            "description": "Sarcoma lower inner quadrant of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "448436006",
            "description": "Sarcoma of central portion of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "448449001",
            "description": "Sarcoma of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "448451002",
            "description": "Sarcoma upper outer quadrant of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "448952004",
            "description": "Infiltrating duct carcinoma of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "45221000119105",
            "description": "Primary invasive malignant neoplasm of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "706970001",
            "description": "Triple negative malignant neoplasm of breast (disorder)",
            "attributes": null
          },
          {
            "code": "708921005",
            "description": "Carcinoma of central portion of breast (disorder)",
            "attributes": null
          },
          {
            "code": "713609000",
            "description": "Invasive carcinoma of breast (disorder)",
            "attributes": null
          },
          {
            "code": "716593008",
            "description": "Carcinoma of salivary gland type of breast (disorder)",
            "attributes": null
          },
          {
            "code": "718220008",
            "description": "Hereditary breast and ovarian cancer syndrome (disorder)",
            "attributes": null
          },
          {
            "code": "721576006",
            "description": "Primary angiosarcoma of breast (disorder)",
            "attributes": null
          },
          {
            "code": "722524005",
            "description": "Primary invasive pleomorphic lobular carcinoma of breast (disorder)",
            "attributes": null
          },
          {
            "code": "722832009",
            "description": "Primary solid papillary carcinoma with invasion of breast (disorder)",
            "attributes": null
          },
          {
            "code": "763479005",
            "description": "Metaplastic carcinoma of breast (disorder)",
            "attributes": null
          },
          {
            "code": "767444009",
            "description": "Germline BRCA-mutated human epidermal growth factor receptor 2 negative metastatic carcinoma of breast (disorder)",
            "attributes": null
          },
          {
            "code": "865954003",
            "description": "Adenocarcinoma of breast (disorder)",
            "attributes": null
          },
          {
            "code": "93680004",
            "description": "Primary malignant neoplasm of areola of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "93681000",
            "description": "Primary malignant neoplasm of areola of male breast (disorder)",
            "attributes": null
          },
          {
            "code": "93745008",
            "description": "Primary malignant neoplasm of central portion of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "93776002",
            "description": "Primary malignant neoplasm of ectopic female breast tissue (disorder)",
            "attributes": null
          },
          {
            "code": "93777006",
            "description": "Primary malignant neoplasm of ectopic male breast tissue (disorder)",
            "attributes": null
          },
          {
            "code": "93796005",
            "description": "Primary malignant neoplasm of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "93874009",
            "description": "Primary malignant neoplasm of lower inner quadrant of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "93876006",
            "description": "Primary malignant neoplasm of lower outer quadrant of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "93884005",
            "description": "Primary malignant neoplasm of male breast (disorder)",
            "attributes": null
          },
          {
            "code": "93924008",
            "description": "Primary malignant neoplasm of nipple of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "93925009",
            "description": "Primary malignant neoplasm of nipple of male breast (disorder)",
            "attributes": null
          },
          {
            "code": "94115006",
            "description": "Primary malignant neoplasm of upper inner quadrant of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "94117003",
            "description": "Primary malignant neoplasm of upper outer quadrant of female breast (disorder)",
            "attributes": null
          },
          {
            "code": "96291000119105",
            "description": "Primary malignant inflammatory neoplasm of female breast (disorder)",
            "attributes": null
          }
        ]
      }
    ],
    "status": 1,
    "doi": "https://doi.org/10.48533/734f-6g61",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "Hongjiao.Liu",
    "template": {
      "id": 2,
      "name": "BHF Data Science Centre Phenotype",
      "description": "BHF Data Science Centre Phenotype definitions that describe a list of clinical codes, algorithms using clinical codes, or set of clinical trials. Visit the BHF Data Science Centre website to learn more: https://bhfdatasciencecentre.org",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 9956,
        "version_name": "CCU022_1 Breast cancer",
        "version_date": "2026-08-18T01:38:58.231771Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]