[
  {
    "phenotype_id": "PH473",
    "phenotype_version_id": 1514,
    "name": "Dementia",
    "definition": "We extracted data on 54,816 people aged 60–89 with dementia and an age-gender stratifiedsample of 205,795 people without dementia from 2001 to 2010 from The Health Improvement Network (THIN), a United Kingdom primary care database. THIN includes data on patients and primary care consultations but does not identify care home residents. Rate ratios were adjusted for age, sex, and co-morbidity using multilevel Poisson regression. The rates of first diagnosis per 1,000 person-years at risk (95% confidence interval) for urinary incontinence in the dementia cohort, among men and women, respectively, were 42.3 (40.9–43.8) and 33.5 (32.6–34.5). In the non-dementia cohort, the rates were 19.8 (19.4–20.3) and 18.6 (18.2–18.9). The rates of first diagnosis for faecal incontinence in the dementia cohort were 11.1 (10.4–11.9) and 10.1 (9.6–10.6). In the non-dementia cohort, the rates were 3.1 (2.9–3.3) and 3.6 (3.5–3.8). The adjusted rate ratio for first diagnosis of urinary incontinence was 3.2 (2.7–3.7) in men and 2.7 (2.3–3.2) in women, and for faecal incontinence was 6.0 (5.1–7.0) in men and 4.5 (3.8–5.2) in women. The adjusted rate ratio for pharmacological treatment of urinary incontinence was 2.2 (1.4–3.7) for both genders, and for indwelling urinary catheters was 1.6 (1.3–1.9) in men and 2.3 (1.9–2.8) in women.\n\n\n\n\n\n\n\n\n",
    "implementation": "",
    "publications": [
      {
        "doi": null,
        "details": "Robert L Grant, Vari M Drennan, Greta Rait, Irene Petersen, Steve Iliffe, First Diagnosis and Management of Incontinence in Older People with and without Dementia in Primary Care A Cohort Study Using The Health Improvement Network Primary Care Database. PLOS medicine, 10:8, 2013."
      }
    ],
    "validation": "",
    "citation_requirements": "",
    "created": "2021-10-06T16:21:06.748093Z",
    "author": "Robert L Grant, Vari M Drennan, Greta Rait, Irene Petersen, Steve Iliffe",
    "collections": [
      {
        "name": "ClinicalCodes Repository",
        "value": 25
      },
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": null,
    "world_access": 1,
    "updated": "2021-10-26T20:18:52.936273Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Disease or syndrome",
        "value": "2"
      }
    ],
    "ontology": null,
    "phenoflowid": "",
    "data_sources": [
      {
        "name": "The Health Improvement Network (THIN)",
        "value": 14,
        "uid": "",
        "url": "",
        "datasource_id": 14
      }
    ],
    "coding_system": [
      {
        "name": "Read codes v2",
        "value": 5
      }
    ],
    "event_date_range": "01/01/2001 - 31/12/2010",
    "concept_information": [
      {
        "concept_id": 1832,
        "concept_version_id": 5511,
        "concept_name": "Dementia - Primary Care",
        "coding_system": {
          "id": 5,
          "name": "Read codes v2",
          "description": "Read codes v2"
        },
        "phenotype_id": "PH473",
        "phenotype_version_id": 1514,
        "phenotype_name": "Dementia",
        "code_attribute_header": [
          "Category",
          "Coding System (Read)",
          "Entity type"
        ],
        "codes": [
          {
            "code": "1461",
            "description": "H/O: dementia",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "E000.00",
            "description": "Uncomplicated senile dementia",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "E001.00",
            "description": "Presenile dementia",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "E001000",
            "description": "Uncomplicated presenile dementia",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "E00..11",
            "description": "Senile dementia",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "E001100",
            "description": "Presenile dementia with delirium",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "E00..12",
            "description": "Senile/presenile dementia",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "E001200",
            "description": "Presenile dementia with paranoia",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "E001300",
            "description": "Presenile dementia with depression",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "E001z00",
            "description": "Presenile dementia NOS",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "E002.00",
            "description": "Senile dementia with depressive or paranoid features",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "E002000",
            "description": "Senile dementia with paranoia",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "E002100",
            "description": "Senile dementia with depression",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "E002z00",
            "description": "Senile dementia with depressive or paranoid features NOS",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "E003.00",
            "description": "Senile dementia with delirium",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "E004.00",
            "description": "Arteriosclerotic dementia",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "E004000",
            "description": "Uncomplicated arteriosclerotic dementia",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "E004100",
            "description": "Arteriosclerotic dementia with delirium",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "E004.11",
            "description": "Multi infarct dementia",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "E004200",
            "description": "Arteriosclerotic dementia with paranoia",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "E004300",
            "description": "Arteriosclerotic dementia with depression",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "E004z00",
            "description": "Arteriosclerotic dementia NOS",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "E041.00",
            "description": "Dementia in conditions EC",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu00.00",
            "description": "[X]Dementia in Alzheimer's disease",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu00000",
            "description": "[X]Dementia in Alzheimer's disease with early onset",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu00011",
            "description": "[X]Presenile dementia,Alzheimer's type",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu00012",
            "description": "[X]Primary degen dementia, Alzheimer's type, presenile onset",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu00013",
            "description": "[X]Alzheimer's disease type 2",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu00100",
            "description": "[X]Dementia in Alzheimer's disease with late onset",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu00111",
            "description": "[X]Alzheimer's disease type 1",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu00112",
            "description": "[X]Senile dementia,Alzheimer's type",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu00113",
            "description": "[X]Primary degen dementia of Alzheimer's type, senile onset",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu00200",
            "description": "[X]Dementia in Alzheimer's dis, atypical or mixed type",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu00z00",
            "description": "[X]Dementia in Alzheimer's disease, unspecified",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu00z11",
            "description": "[X]Alzheimer's dementia unspec",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu01.00",
            "description": "[X]Vascular dementia",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu01000",
            "description": "[X]Vascular dementia of acute onset",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu01100",
            "description": "[X]Multi-infarct dementia",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu01.11",
            "description": "[X]Arteriosclerotic dementia",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu01111",
            "description": "[X]Predominantly cortical dementia",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu01200",
            "description": "[X]Subcortical vascular dementia",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu01300",
            "description": "[X]Mixed cortical and subcortical vascular dementia",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu01y00",
            "description": "[X]Other vascular dementia",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu01z00",
            "description": "[X]Vascular dementia, unspecified",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu02z00",
            "description": "[X] Unspecified dementia",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu02z11",
            "description": "[X] Presenile dementia NOS",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu02z13",
            "description": "[X] Primary degenerative dementia NOS",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu02z14",
            "description": "[X] Senile dementia NOS",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu02z16",
            "description": "[X] Senile dementia, depressed or paranoid type",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Eu04100",
            "description": "[X]Delirium superimposed on dementia",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "F110.00",
            "description": "Alzheimer's disease",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "F110000",
            "description": "Alzheimer's disease with early onset",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "F110100",
            "description": "Alzheimer's disease with late onset",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          },
          {
            "code": "Fyu3000",
            "description": "[X]Other Alzheimer's disease",
            "attributes": {
              "Category": "diagnostic",
              "Coding System (Read)": "Read",
              "Entity type": "res11: Dementia"
            }
          }
        ]
      }
    ],
    "status": 2,
    "doi": "https://doi.org/10.48533/17dr-y605",
    "is_deleted": null,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 1,
      "name": "Clinical-Coded Phenotype",
      "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 1514,
        "version_name": "Dementia",
        "version_date": "2021-10-26T20:18:53.172046Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]