[
  {
    "phenotype_id": "PH542",
    "phenotype_version_id": 1084,
    "name": "Lithium Therapy",
    "definition": "The study period extended from 1 April 2004, the date of introduction of the incentivisation scheme, to 31 March 2012. Practices’ performance under the QOF is measured over a financial year, so we divided the study period into eight financial years (1 April to 31 March the following year). Not all 644 practices provided research standard data (as assessed by the CPRD assessment algorithm) for the whole period. Within each year, we identified practices that reliably contributed data for the whole year. Our main dataset comprised this group of practices, which varies over time. We also generated two alternative datasets with which to assess the sensitivity of our findings. For the first, we included 452 practices that were continuously active and up to standard for the whole of the study period; for the second, we selected a subsample of 50 practices that were most representative of UK practices in terms of list sizes of patients and area deprivation according to the Index of Multiple Deprivation,13 14 two of the most important predictors of QOF performance.12 15 16 In each of the three datasets, for each financial year, we defined “eligible” patients as those registered with an included practice for the full year.\n\n\n\n\n\n\n\n\n",
    "implementation": "",
    "publications": [
      {
        "doi": null,
        "details": "Evangelos Kontopantelis, David Springate, David Reeves, Darren M Ashcroft, Jose M Valderas, Tim Doran, Withdrawing performance indicators: retrospective analysis of general practice performance under UK Quality and Outcomes Framework. BMJ, 348:g330, 2014."
      }
    ],
    "validation": "",
    "citation_requirements": "",
    "created": "2021-10-06T16:24:19.653726Z",
    "author": "Evangelos Kontopantelis, David Springate, David Reeves, Darren M Ashcroft, Jose M Valderas, Tim Doran",
    "collections": [
      {
        "name": "ClinicalCodes Repository",
        "value": 25
      },
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": null,
    "world_access": 1,
    "updated": "2021-10-06T16:24:19.653754Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Drug",
        "value": "3"
      }
    ],
    "ontology": null,
    "phenoflowid": "",
    "data_sources": [
      {
        "name": "CPRD GOLD",
        "value": 5,
        "uid": "a29feafa-7bdd-44e9-b977-c9d26425e67f",
        "url": "https://healthdatagateway.org/en/dataset/694",
        "datasource_id": 694
      }
    ],
    "coding_system": [
      {
        "name": "Read codes v2",
        "value": 5
      },
      {
        "name": "OXMIS codes",
        "value": 15
      }
    ],
    "event_date_range": "01/04/2004 - 31/03/2021",
    "concept_information": [
      {
        "concept_id": 1932,
        "concept_version_id": 5002,
        "concept_name": "Lithium Therapy - Primary Care",
        "coding_system": {
          "id": 5,
          "name": "Read codes v2",
          "description": "Read codes v2"
        },
        "phenotype_id": "PH542",
        "phenotype_version_id": 1084,
        "phenotype_name": "Lithium Therapy",
        "code_attribute_header": [
          "Entity type",
          "Coding System (OXMIS Read)",
          "Category"
        ],
        "codes": [
          {
            "code": "44vE.00",
            "description": "Lithium level therapeutic",
            "attributes": {
              "Entity type": "lithium_therapy",
              "Coding System (OXMIS Read)": "Read",
              "Category": "diagnostic"
            }
          },
          {
            "code": "44W8.00",
            "description": "Serum lithium level",
            "attributes": {
              "Entity type": "lithium_therapy",
              "Coding System (OXMIS Read)": "Read",
              "Category": "diagnostic"
            }
          },
          {
            "code": "44W8000",
            "description": "Lithium level therapeutic",
            "attributes": {
              "Entity type": "lithium_therapy",
              "Coding System (OXMIS Read)": "Read",
              "Category": "diagnostic"
            }
          },
          {
            "code": "44W8100",
            "description": "Lithium level high - toxic",
            "attributes": {
              "Entity type": "lithium_therapy",
              "Coding System (OXMIS Read)": "Read",
              "Category": "diagnostic"
            }
          },
          {
            "code": "44W8.11",
            "description": "Lithium: blood level",
            "attributes": {
              "Entity type": "lithium_therapy",
              "Coding System (OXMIS Read)": "Read",
              "Category": "diagnostic"
            }
          },
          {
            "code": "44W8200",
            "description": "Lithium level low",
            "attributes": {
              "Entity type": "lithium_therapy",
              "Coding System (OXMIS Read)": "Read",
              "Category": "diagnostic"
            }
          },
          {
            "code": "6657.00",
            "description": "On lithium",
            "attributes": {
              "Entity type": "lithium_therapy",
              "Coding System (OXMIS Read)": "Read",
              "Category": "diagnostic"
            }
          },
          {
            "code": "6657.11",
            "description": "Lithium monitoring",
            "attributes": {
              "Entity type": "lithium_therapy",
              "Coding System (OXMIS Read)": "Read",
              "Category": "diagnostic"
            }
          },
          {
            "code": "6657.12",
            "description": "Started lithium",
            "attributes": {
              "Entity type": "lithium_therapy",
              "Coding System (OXMIS Read)": "Read",
              "Category": "diagnostic"
            }
          },
          {
            "code": "665B.00",
            "description": "Lithium stopped",
            "attributes": {
              "Entity type": "lithium_therapy",
              "Coding System (OXMIS Read)": "Read",
              "Category": "diagnostic"
            }
          },
          {
            "code": "9859",
            "description": "TOXICITY LITHIUM",
            "attributes": {
              "Entity type": "lithium_therapy",
              "Coding System (OXMIS Read)": "Read",
              "Category": "diagnostic"
            }
          },
          {
            "code": "R105300",
            "description": "[D]Lithium; blood level abnormal",
            "attributes": {
              "Entity type": "lithium_therapy",
              "Coding System (OXMIS Read)": "Read",
              "Category": "diagnostic"
            }
          },
          {
            "code": "T3551CA",
            "description": "LITHIUM THERAPY",
            "attributes": {
              "Entity type": "lithium_therapy",
              "Coding System (OXMIS Read)": "Read",
              "Category": "diagnostic"
            }
          }
        ]
      },
      {
        "concept_id": 1933,
        "concept_version_id": 5004,
        "concept_name": "Lithium Therapy - Primary Care",
        "coding_system": {
          "id": 15,
          "name": "OXMIS codes",
          "description": "OXMIS codes"
        },
        "phenotype_id": "PH542",
        "phenotype_version_id": 1084,
        "phenotype_name": "Lithium Therapy",
        "code_attribute_header": [
          "Entity type",
          "Coding System (OXMIS Read)",
          "Category"
        ],
        "codes": [
          {
            "code": "L 130L",
            "description": "SERUM LITHIUM LEVEL",
            "attributes": {
              "Entity type": "lithium_therapy",
              "Coding System (OXMIS Read)": "OXMIS",
              "Category": "diagnostic"
            }
          },
          {
            "code": "L 130LA",
            "description": "LITHIUM LEVEL",
            "attributes": {
              "Entity type": "lithium_therapy",
              "Coding System (OXMIS Read)": "OXMIS",
              "Category": "diagnostic"
            }
          },
          {
            "code": "L 130LB",
            "description": "LITHIUM LEVEL LOW",
            "attributes": {
              "Entity type": "lithium_therapy",
              "Coding System (OXMIS Read)": "OXMIS",
              "Category": "diagnostic"
            }
          },
          {
            "code": "L 130LC",
            "description": "LITHIUM LEVEL THERAPEUTIC",
            "attributes": {
              "Entity type": "lithium_therapy",
              "Coding System (OXMIS Read)": "OXMIS",
              "Category": "diagnostic"
            }
          },
          {
            "code": "L 130LD",
            "description": "LITHIUM LEVEL HIGH",
            "attributes": {
              "Entity type": "lithium_therapy",
              "Coding System (OXMIS Read)": "OXMIS",
              "Category": "diagnostic"
            }
          }
        ]
      }
    ],
    "status": 2,
    "doi": "https://doi.org/10.48533/1wyn-rp07",
    "is_deleted": null,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 1,
      "name": "Clinical-Coded Phenotype",
      "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 1084,
        "version_name": "Lithium Therapy",
        "version_date": "2021-10-06T16:24:19.681703Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]