[ { "phenotype_id": "PH543", "phenotype_version_id": 1086, "name": "Loop Diuretics", "definition": "Data source: \n\nWe used the Clinical Practice Research Datalink (CPRD), a large primary care database that holds complete electronic patient records (including diagnoses, prescriptions and referrals) from participating family practices across the UK. A hierarchical clinical coding system (Read) is used to record the data. In July 2012, data were available for 644 practices and 13,772,992 patients. Full details of the database have been provided elsewhere.\n\n\nDiabetes cohort:\n\nWe extracted data from 1 April 2006 to 31 March 2012 and, for ease of reporting and analysing, aggregated information into six financial years. Within each year, practice inclusion eligibility was determined by a CPRD assessment algorithm, which informs on practices considered to be of research standard; therefore, our cohort of practices varied over time. For each research standard practice and year, we defined as eligible patients those who were registered with the practice for the full year and were aged 18 years or over in that year. From these patients, using relevant Read codes for type 2 diabetes (e.g. C10F.00: Type 2 diabetes mellitus) and excluding those treated with insulin within 2 years of diagnosis, we identified 246,544 patients over the study period. Diagnoses were not constrained to the study period and a relevant code prior to the study as well as during the study period would flag a patient from the respective year onwards. Data on sex, age and removal from the database due to deaths were available and complete for all patients.We extracted data on diabetes-related macrovascular (myocardial infarction, stroke, peripheral vascular disease or amputation) and microvascular (retinopathy, neuropathy, nephropathy [chronic kidney disease stages 4–5] or foot ulcer) complications as well as comorbidities (asthma, coronary heart disease, chronic kidney disease [excluded from microvascular analysis], chronic obstructive pulmonary disease, depression, dementia, severe mental illness, heart failure, hypertension, stroke [excluded from macrovascular analysis], cancer, epilepsy, osteoarthritis, osteoporosis and hypothyroidism). Although we aimed to include all conditions associated with diabetes, the choice was partially determined by the domains incentivised under the Quality and Outcomes Framework (QOF), for which accuracy of diagnosis is considered high. Information was also extracted on smoking (never smoked, current, exsmoker and missing data),BMI, HbA1c levels (%), cholesterol levels (mmol/l) and systolic/diastolic BP (mmHg). Biometric measurement data were cleaned and we calculated patient means for each year when more than one relevant record was available. Using product lists we determined prescription prevalence (at least one) for relevant medications: ACE inhibitors, acarbose, α-blockers, anticoagulants, antiplatelet agents, β-blockers, calcium-channel blockers, thiazide diuretics, loop diuretics, dipeptidyl peptidase-4 inhibitors, glucagon-like peptide- 1 agonists, statins and other lipid-lowering drugs, meglitinides , metformin, sulfonylureas and thiazolidinediones. For approximately 60% of the practices, records were linked to Office of National Statistics (ONS) mortality data and we had access to death dates for all their patients. For these, using ICD-10 codes (www.who.int/classifications/icd/en/) we were able to estimate deathslinked to specific causes (underlying or in the top three): diabetes (E10–E16), ischaemic heart disease (I21–I22), stroke (I60–I64) or stroke excluding bleeds (excluding I63).\n\n\n\n\n\n\n\n\n", "implementation": "", "publications": [ { "doi": null, "details": "Evangelos Kontopantelis, David A Springate, David Reeves, Darren M. Aschroff, Martin Rutter, Iain Buchan, Tim Doran, Glucose, blood pressure and cholesterol levels and their relationships to clinical outcomes in type 2 diabetes: a retrospective cohort study. Diabetologia, 58:505-518, 2015. " } ], "validation": "", "citation_requirements": "", "created": "2021-10-06T16:24:21.829419Z", "author": "Evangelos Kontopantelis, David A Springate, David Reeves, Darren M. Aschroff, Martin Rutter, Iain Buchan, Tim Doran, Matthias Pierce, Darren M. Ashcroft", "collections": [ { "name": "ClinicalCodes Repository", "value": 25 }, { "name": "Phenotype Library", "value": 18 } ], "tags": null, "organisation": null, "world_access": 1, "updated": "2021-10-06T16:24:21.829447Z", "sex": [ { "name": "Both", "value": "3" } ], "type": [ { "name": "Drug", "value": "3" } ], "ontology": null, "phenoflowid": "", "data_sources": [ { "name": "CPRD GOLD", "value": 5, "uid": "a29feafa-7bdd-44e9-b977-c9d26425e67f", "url": "https://healthdatagateway.org/en/dataset/694", "datasource_id": 694 } ], "coding_system": [ { "name": "GPRD product codes", "value": 14 } ], "event_date_range": "01/04/2006 - 31/03/2012", "concept_information": [ { "concept_id": 1934, "concept_version_id": 5006, "concept_name": "Loop Diuretics - Primary Care", "coding_system": { "id": 14, "name": "GPRD product codes", "description": "GPRD product codes" }, "phenotype_id": "PH543", "phenotype_version_id": 1086, "phenotype_name": "Loop Diuretics", "code_attribute_header": [ "Coding System (CPRD_product_code)", "Entity type", "Category" ], "codes": [ { "code": "10066", "description": "TOREM tablets 5mg [MEDA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "10392", "description": "LASIX tablets 500mg [BORG]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "10781", "description": "LASIX + K tablets [HOECHSTMAR]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "11265", "description": "triamterene with furosemide tablets 50mg + 40mg ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "11268", "description": "TOREM tablets 2.5mg [MEDA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "11487", "description": "torasemide tablets 2.5mg ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "12226", "description": "BURINEX oral liquid sugar-free 1mg/5ml [LEO]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "12294", "description": "BURINEX tablets 5mg [LEO]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "12354", "description": "etacrynic acid tablets 50mg ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "12367", "description": "piretanide capsules 6mg ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "1301", "description": "FRUMIL LS tablets 20mg + 2.5mg [HELIOS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "13435", "description": "FRUMIL forte tablets 80mg + 10mg [HELIOS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "1369", "description": "furosemide with amiloride tablets 40mg + 5mg ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "14587", "description": "amiloride hydrochloride with bumetanide tablets 5mg + 1mg ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "14761", "description": "FRUSID tablets 40mg [DDSA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "14837", "description": "FRUSOL oral solution sugar-free 50mg/5ml [ROSEMONT]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "15874", "description": "amiloride hydrochloride with furosemide tablets 2.5mg + 20mg ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "16206", "description": "FROOP 40 tablets 40mg [ASHBOURNE]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "1776", "description": "BURINEX K tablets 500micrograms + 7.7mmol [LEO]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "17960", "description": "furosemide with potassium tablets 20mg + 10mmol ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "18096", "description": "torasemide tablets 10mg ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "18332", "description": "ARIDIL tablets 20mg + 2.5mg [CP PHARM]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "18497", "description": "amiloride hydrochloride with furosemide tablets 10mg + 80mg ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "18650", "description": "EDECRIN tablets 50mg [M S D]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "18983", "description": "BRINALDIX K effervescent tablet [BERK]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "19056", "description": "FUROSEMIDE solution sugar-free 50mg/5ml [ROSEMONT]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "19192", "description": "FUROSEMIDE tablets 40mg [M&A PHARM]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "19194", "description": "FUROSEMIDE tablets 20mg [TEVA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "193", "description": "co-amilofruse (amiloride and furosemide) tablets 2.5mg+20mg ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "20538", "description": "FRUMAX tablets 40mg [ASHBOURNE]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "211", "description": "FRUMIL tablets 40mg + 5mg [HELIOS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "21849", "description": "DRYPTAL tablets 40mg [BERK]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "21938", "description": "FROOP-CO tablets 5mg+40mg [ASHBOURNE]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "22658", "description": "TOREM tablets 10mg [MEDA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "22839", "description": "clopamide with potassium effervescent tablet ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "24832", "description": "LASIPRESSIN tablets [HOECHST]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "2493", "description": "BURINEX A tablets [LEO]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "2495", "description": "bumetanide with amiloride tablets ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "25334", "description": "FUROSEMIDE tablets 500mg [HILLCROSS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "25717", "description": "FUROSEMIDE tablets 40mg [GEN (UK)]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "25965", "description": "CO-AMILOFRUSE tablets 2.5mg+20mg [WOCKHARDT]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "26292", "description": "DIURESAL tablets 40mg [LAGAP]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "26529", "description": "furosemide with penbutolol tablets ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "27447", "description": "FUROSEMIDE tablets 40mg [CP PHARM]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "27690", "description": "FUROSEMIDE tablets 40mg [HILLCROSS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "27696", "description": "FUROSEMIDE tablets 40mg [KENT]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "2772", "description": "LASORIDE tablets [BORG]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "2788", "description": "BURINEX tablets 1mg [LEO]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "27926", "description": "FUROSEMIDE tablets 20mg [GEN (UK)]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "28129", "description": "CO-AMILOFRUSE tablets 5mg+40mg [TEVA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "2961", "description": "FRUSENE tablets [ORION]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "29780", "description": "FUROSEMIDE tablets 20mg [CP PHARM]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "3050", "description": "furosemide with triamterene tablets 40mg + 50mg ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "30625", "description": "FUROSEMIDE tablets 20mg [HILLCROSS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "30773", "description": "CO-AMILOFRUSE tablets 5mg+40mg [BERK]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "30913", "description": "BETINEX tablets 1mg [BERK]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "31548", "description": "FUROSEMIDE tablets 20mg [ACTAVIS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "31773", "description": "CO-AMILOFRUSE tablets 5mg+40mg [WOCKHARDT]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "31932", "description": "BUMETANIDE tablets 1mg [CP PHARM]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "32091", "description": "BUMETANIDE tablets 1mg [HILLCROSS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "3248", "description": "furosemide tablets 500mg ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "32896", "description": "FUROSEMIDE tablets 40mg [RANBAXY]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "32918", "description": "FUROSEMIDE tablets 20mg [SANDOZ]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "33527", "description": "CO-AMILOFRUSE tablets 5mg+40mg [GEN (UK)]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "33658", "description": "CO-AMILOFRUSE tablets 5mg+40mg [HILLCROSS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "34006", "description": "FUROSEMIDE tablets 40mg [ACTAVIS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "34280", "description": "CO-AMILOFRUSE tablets 2.5mg+20mg [SANDOZ]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "34374", "description": "FUROSEMIDE tablets 40mg [TEVA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "34557", "description": "FUROSEMIDE tablets 40mg [IVAX]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "34613", "description": "BUMETANIDE tablets 5mg [TEVA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "34622", "description": "CO-AMILOFRUSE tablets 10mg+80mg [WOCKHARDT]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "34934", "description": "BUMETANIDE tablets 1mg [GEN (UK)]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "36190", "description": "furosemide oral solution sugar-free 5mg/5ml ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "36767", "description": "BUMETANIDE tablets 1mg [IVAX]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "3793", "description": "co-amilofruse (amiloride and furosemide) tablets 10mg+80mg ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "38901", "description": "FRUMIL LS tablets 20mg + 2.5mg [SANOFI/AVE]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "39602", "description": "BUMETANIDE tablets 1mg [ACTAVIS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "39807", "description": "FRUMIL tablets 40mg + 5mg [SANOFI/AVE]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "40898", "description": "TORASEMIDE tablets 5mg [HILLCROSS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "41292", "description": "FUROSEMIDE tablets 20mg [WOCKHARDT]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "41405", "description": "FUROSEMIDE tablets 500mg [TEVA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "41533", "description": "CO-AMILOFRUSE tablets 2.5mg+20mg [TEVA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "41719", "description": "CO-AMILOFRUSE tablets 5mg+40mg [ACTAVIS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "41828", "description": "FUROSEMIDE tablets 500mg [ACTAVIS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "4211", "description": "furosemide with amiloride tablets 20mg + 2.5mg ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "42388", "description": "FUROSEMIDE oral solution sugar-free 40mg/5ml [FOCUS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "42488", "description": "FUROSEMIDE oral solution 40mg/5ml [HILLCROSS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "43508", "description": "CO-AMILOFRUSE tablets 5mg+40mg [SANDOZ]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "45305", "description": "BUMETANIDE tablets 1mg [TEVA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "46525", "description": "TORASEMIDE tablets 5mg [TEVA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "4661", "description": "spironolactone with furosemide capsules 50mg + 20mg ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "46699", "description": "FUROSEMIDE tablets 40mg [ALMUS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "46948", "description": "FUROSEMIDE tablets 40mg [ARROW]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "47647", "description": "co-amilofruse oral liquid ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "47815", "description": "FUROSEMIDE tablets 20mg [CELLTECH]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "4873", "description": "FRU-CO tablets 5mg + 40mg [IVAX]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "5218", "description": "bumetanide oral liquid sugar-free 1mg/5ml ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "5220", "description": "furosemide with amiloride tablets 80mg + 10mg ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "5249", "description": "furosemide oral solution sugar-free 50mg/5ml ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "55", "description": "furosemide tablets 20mg ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "56", "description": "co-amilofruse (amiloride and furosemide) tablets 5mg+40mg ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "5728", "description": "furosemide oral solution sugar-free 40mg/5ml ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "5868", "description": "FRUSOL oral solution sugar-free 20mg/5ml [ROSEMONT]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "6", "description": "furosemide tablets 40mg ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "6118", "description": "furosemide oral solution sugar-free 20mg/5ml ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "6160", "description": "bumetanide with potassium tablets 500micrograms + 7.7mmol ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "7441", "description": "LASILACTONE capsules [SANOFI/AVE]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "7582", "description": "LASIKAL tablets 20mg + 10mmol [BORG]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "7606", "description": "LASIX tablets 40mg [BORG]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "7709", "description": "ARELIX capsules 6mg [HOECHSTMAR]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "7734", "description": "DIUMIDE-K CONTINUS tablets [TEOFARMA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "7799", "description": "LASIX tablets 20mg [BORG]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "7806", "description": "bumetanide tablets 5mg ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "8052", "description": "torasemide tablets 5mg ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "8102", "description": "furosemide with potassium tablets 40mg + 8mmol ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "814", "description": "bumetanide tablets 1mg ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "9431", "description": "FRUSEMEK tablets 40mg + 5mg [APS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "9456", "description": "amiloride hydrochloride with furosemide tablets 5mg + 40mg ", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } }, { "code": "9680", "description": "FRUSOL oral solution sugar-free 40mg/5ml [ROSEMONT]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res9: loop_diuretics", "Category": "drug" } } ] } ], "status": 2, "doi": "https://doi.org/10.48533/e1y6-h247", "is_deleted": null, "publish_status": 2, "owner": "ieuan.scanlon", "template": { "id": 1, "name": "Clinical-Coded Phenotype", "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.", "version_id": 1 }, "versions": [ { "version_id": 1086, "version_name": "Loop Diuretics", "version_date": "2021-10-06T16:24:21.857933Z", "is_published": true, "is_latest": true } ] } ]