[ { "phenotype_id": "PH574", "phenotype_version_id": 1148, "name": "End-Stage Renal Disease (ESRD)", "definition": "Objective: \n\nTo investigate whether there is an association between use of ACE inhibitors (ACEI) and angiotensin receptor blockers (ARB), and risk of acute kidney injury (AKI).\n\n\nDesign: \n\nA time-updated, new-user cohort study among people initiating common antihypertensives (ACEI/ARB, beta-blockers, calcium channel blockers and thiazide diuretics) in primary care between April 1997 and March 2014.\n\n\nParticipants: \n\nAdults initiating antihypertensive drug treatment, with at least one year of registration prior to first prescription, identified from UK primary care practices contributing to the Clinical Practice Research Datalink and eligible for linkage to hospital records data from the Hospital Episode Statistics database.\n\n\nMain outcome measures: \n\nIncidence rate ratio (RR) for first episode of AKI during time exposed to ACEI/ARB compared to time unexposed, estimated using Poisson regression adjusted for age, sex, comorbidities, use of other antihypertensive drugs, and calendar period.\n\n\nResults: \n\nAmong 570,443 participants with a median follow-up of 2.8 years (IQR 0.4 to 7) there were 15,004 first cases of AKI. The overall crude rate of AKI was 6.4/1,000 person years at risk (95% CI 6.30 to 6.50) but varied from 1.63 (1.43 to 1.86) to 662.53 (538.98 to 814.40) depending on, age, comorbidities, and other prescribed drugs. The adjusted RR of AKI during time exposed to ACEI/ARB compared to time unexposed was 1.18 (95% CI 1.13 to 1.23) which was attenuated to 1.12 (95% CI 1.08 to 1.17) after adjustment for non-thiazide diuretic therapy. There was an interaction for the risk of AKI between people using loop diuretics and ACEI/ARB. For those taking loop diuretics, the adjusted RR of AKI during time exposed to ACEI/ARB compared to time unexposed was 0.99 (95% CI 0.92 to 1.06) but it was 1.18 (95% CI 1.13 to 1.24) among people not-exposed to loop diuretics (p<0.001).\n\n\nConclusions: \n\nTreatment with ACEI/ARB alone appears to be associated with a small increase in the rate of AKI which is largely seen among people with low absolute risk of AKI. Among people requiring loop diuretics, who have a high absolute risk of AKI, treatment with ACEI/ARB had no measurable association with AKI.\n\n\n\n\n\n\n\n\n", "implementation": "", "publications": [ { "doi": null, "details": "Kethryn E Mansfield, Dorothea Nitsch, Liam Smeeth, Krishnan Bhaskaram, Laurie A Tomlinson, Renin-angiostensin system blockage and risk of acute kidney injury. 2015." } ], "validation": "", "citation_requirements": "", "created": "2021-10-06T16:25:27.546968Z", "author": "Kethryn E Mansfield, Dorothea Nitsch, Liam Smeeth, Krishnan Bhaskaram, Laurie A Tomlinson", "collections": [ { "name": "ClinicalCodes Repository", "value": 25 }, { "name": "Phenotype Library", "value": 18 } ], "tags": null, "organisation": null, "world_access": 1, "updated": "2021-10-06T16:25:27.546997Z", "sex": [ { "name": "Both", "value": "3" } ], "type": [ { "name": "Disease or syndrome", "value": "2" } ], "ontology": null, "phenoflowid": "", "data_sources": [ { "name": "CPRD GOLD", "value": 5, "uid": "a29feafa-7bdd-44e9-b977-c9d26425e67f", "url": "https://healthdatagateway.org/en/dataset/694", "datasource_id": 694 }, { "name": "HES Admitted Patient Care data for CPRD GOLD", "value": 9, "uid": "4bcf64a6-f404-4ef4-ae6e-172512ab5f43", "url": "https://healthdatagateway.org/en/dataset/674", "datasource_id": 674 } ], "coding_system": [ { "name": "ICD10 codes", "value": 4 }, { "name": "Read codes v2", "value": 5 } ], "event_date_range": "01/04/1997 - 31/03/2014", "concept_information": [ { "concept_id": 1976, "concept_version_id": 5090, "concept_name": "End-Stage Renal Disease (ESRD) - Primary Care", "coding_system": { "id": 5, "name": "Read codes v2", "description": "Read codes v2" }, "phenotype_id": "PH574", "phenotype_version_id": 1148, "phenotype_name": "End-Stage Renal Disease (ESRD)", "code_attribute_header": [ "Entity type", "Category", "Coding System (ICD-10 Read)" ], "codes": [ { "code": "14S2.00", "description": "h/o: kidney recipient", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "14V2.00", "description": "h/o: renal dialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "14V2.11", "description": "h/o: kidney dialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "1Z14.00", "description": "chronic kidney disease stage 5", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "1Z1K.00", "description": "chronic kidney disease stage 5 with proteinuria", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "1Z1K.11", "description": "ckd stage 5 with proteinuria", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "1Z1L.00", "description": "chronic kidney disease stage 5 without proteinuria", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "1Z1L.11", "description": "ckd stage 5 without proteinuria", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "4I29.00", "description": "peritoneal dialysis sample", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "4N0..00", "description": "dialysis fluid urea level", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "4N2..00", "description": "dialysis fluid glucose level", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "67P4100", "description": "discussion about kidney transplantation", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7A60.00", "description": "arteriovenous shunt", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7A60000", "description": "insertion of arteriovenous prosthesis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7A60100", "description": "creation of arteriovenous fistula nec", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7A60111", "description": "creation of radial-cephalic fistula", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7A60112", "description": "creation of brachial-cephalic fistula", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7A60200", "description": "attention to arteriovenous shunt", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7A60300", "description": "removal of infected arteriovenous shunt", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7A60400", "description": "banding of arteriovenous fistula", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7A60500", "description": "thrombectomy of arteriovenous fistula", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7A60600", "description": "creation of graft fistula for dialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7A60y00", "description": "other specified arteriovenous shunt", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7A60z00", "description": "arteriovenous shunt nos", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7A61100", "description": "repair of acquired arteriovenous fistula", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7A61111", "description": "ligation of acquired arteriovenous fistula", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7A61400", "description": "ligation of acquired arteriovenous fistula", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7A61900", "description": "ligation of arteriovenous dialysis fistula", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7A61A00", "description": "ligation of arteriovenous dialysis graft", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7B00.00", "description": "transplantation of kidney", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7B00100", "description": "transplantation of kidney from live donor", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7B00111", "description": "allotransplantation of kidney from live donor", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7B00200", "description": "transplantation of kidney from cadaver", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7B00211", "description": "allotransplantation of kidney from cadaver", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7B00212", "description": "cadaveric renal transplant", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7B00300", "description": "allotransplantation of kidney from cadaver heart-beating", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7B00400", "description": "allotransplantation kidney from cadaver heart non-beating", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7B00600", "description": "xenograft renal transplant", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7B00y00", "description": "other specified transplantation of kidney", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7B00z00", "description": "transplantation of kidney nos", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7B01500", "description": "transplant nephrectomy", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7B01511", "description": "excision of rejected transplanted kidney", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7B06300", "description": "exploration of renal transplant", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7B0F.00", "description": "interventions associated with transplantation of kidney", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7B0F100", "description": "pre-transplantation of kidney work-up, recipient", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7B0F300", "description": "post-transplantation of kidney examination, recipient", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7B0Fy00", "description": "os interventions associated with transplantation of kidney", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7B0Fz00", "description": "interventions associated with transplantation of kidney nos", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7L1A.00", "description": "compensation for renal failure", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7L1A000", "description": "renal dialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7L1A011", "description": "thomas intravascular shunt for dialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7L1A100", "description": "peritoneal dialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7L1A.11", "description": "dialysis for renal failure", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7L1A200", "description": "haemodialysis nec", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7L1A300", "description": "haemofiltration", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7L1A400", "description": "automated peritoneal dialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7L1A500", "description": "continuous ambulatory peritoneal dialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7L1A600", "description": "peritoneal dialysis nec", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7L1Ay00", "description": "other specified compensation for renal failure", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7L1Az00", "description": "compensation for renal failure nos", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7L1B.00", "description": "placement ambulatory apparatus compensation renal failure", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7L1B000", "description": "insertion of ambulatory peritoneal dialysis catheter", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7L1B100", "description": "removal of ambulatory peritoneal dialysis catheter", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7L1B.11", "description": "placement ambulatory dialysis apparatus - compens renal fail", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7L1B200", "description": "flushing of peritoneal dialysis catheter", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7L1By00", "description": "placement ambulatory apparatus- compensate renal failure os", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7L1C.00", "description": "placement other apparatus for compensation for renal failure", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7L1C000", "description": "insertion of temporary peritoneal dialysis catheter", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7L1Cy00", "description": "placement other apparatus- compensate for renal failure os", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "7L1Cz00", "description": "placement other apparatus- compensate for renal failure nos", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "8L50.00", "description": "renal transplant planned", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "9b8K.00", "description": "transplantation surgery", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "9Ot5.00", "description": "predicted stage chronic kidney disease", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "G72C.00", "description": "ruptured aneurysm of dialysis vascular access", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "G72D.00", "description": "aneurysm of dialysis arteriovenous fistula", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "G72D100", "description": "aneurysm of needle site of dialysis arteriovenous fistula", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "G72D200", "description": "aneurysm of anastomotic site of dialysis av fistula", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "G760.00", "description": "acquired arteriovenous fistula", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "Gy1..00", "description": "stenosis of dialysis vascular access", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "Gy21.00", "description": "thrombosis of dialysis arteriovenous fistula", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "Gy3..00", "description": "occlusion of dialysis vascular access", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "Gy31.00", "description": "occlusion of dialysis arteriovenous fistula", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "Gy40.00", "description": "infection of dialysis arteriovenous graft", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "Gy41.00", "description": "infection of dialysis arteriovenous fistula", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "Gy51.00", "description": "haemorrhage of dialysis arteriovenous fistula", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "Gy60.00", "description": "rupture of dialysis arteriovenous graft", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "K050.00", "description": "end stage renal failure", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "K05..12", "description": "end stage renal failure", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "K055.00", "description": "chronic kidney disease stage 5", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "K0B5.00", "description": "renal tubulo-interstitial disordrs in transplant rejectn", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "K0D..00", "description": "end-stage renal disease", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "Kyu1C00", "description": "[x]renal tubulo-interstitial disorders/transplant rejection", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "SP01500", "description": "mechanical complication of dialysis catheter", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "SP01700", "description": "mechanical complication of arterio-venous surgical fistula", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "SP05613", "description": "[x] peritoneal dialysis associated peritonitis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "SP06B00", "description": "continuous ambulatory peritoneal dialysis associated perit", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "SP07G00", "description": "stenosis of arteriovenous dialysis fistula", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "SP07N00", "description": "arteriovenous fistula thrombosis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "SP08011", "description": "det.ren.func.after ren.transpl", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "SP08300", "description": "kidney transplant failure and rejection", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "SP08J00", "description": "chronic rejection of renal transplant", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "SP08N00", "description": "unexplained episode of renal transplant dysfunction", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "SP08R00", "description": "renal transplant rejection", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "SP08T00", "description": "urological complication of renal transplant", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "SP08W00", "description": "vascular complication of renal transplant", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "SP0E.00", "description": "disorders associated with peritoneal dialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "SP0G.00", "description": "anaphylactoid reaction due to haemodialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "TA02000", "description": "accid cut,puncture,perf,h'ge - kidney dialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "TA22.00", "description": "failure of sterile precautions during perfusion", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "TA22000", "description": "failure of sterile precautions during kidney dialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "TB00100", "description": "kidney transplant with complication, without blame", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "TB00111", "description": "renal transplant with complication, without blame", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "TB11.00", "description": "kidney dialysis with complication, without blame", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "TB11.11", "description": "renal dialysis with complication, without blame", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "U612200", "description": "[x]failure sterile precautions dur kidney dialys/other perf", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "Z1A..00", "description": "dialysis training", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "Z1A1.00", "description": "peritoneal dialysis training", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "Z1A2.00", "description": "haemodialysis training", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "Z919.00", "description": "care of haemodialysis equipment", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "Z919100", "description": "priming haemodialysis lines", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "Z919300", "description": "reversing haemodialysis lines", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "Z91A.00", "description": "peritoneal dialysis bag procedure", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "ZV42000", "description": "[v]kidney transplanted", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "ZV45100", "description": "[v]renal dialysis status", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "ZV56.00", "description": "[v]aftercare involving intermittent dialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "ZV56000", "description": "[v]aftercare involving extracorporeal dialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "ZV56011", "description": "[v]aftercare involving renal dialysis nos", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "ZV56100", "description": "[v]preparatory care for dialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "ZV56y00", "description": "[v]other specified aftercare involving intermittent dialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "ZV56y11", "description": "[v]aftercare involving peritoneal dialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } }, { "code": "ZVu3G00", "description": "[x]other dialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "Read" } } ] }, { "concept_id": 1977, "concept_version_id": 5092, "concept_name": "End-Stage Renal Disease (ESRD) - Primary Care", "coding_system": { "id": 4, "name": "ICD10 codes", "description": "ICD10 Codes" }, "phenotype_id": "PH574", "phenotype_version_id": 1148, "phenotype_name": "End-Stage Renal Disease (ESRD)", "code_attribute_header": [ "Entity type", "Category", "Coding System (ICD-10 Read)" ], "codes": [ { "code": "I77.0", "description": "arteriovenous fistula, acquired", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "ICD-10" } }, { "code": "N16.5", "description": "renal tubulo-interstitial disorders in transplant rejection", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "ICD-10" } }, { "code": "N18.5", "description": "chronic kidney disease, stage 5", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "ICD-10" } }, { "code": "T82.4", "description": "mechanical complication of vascular dialysis catheter", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "ICD-10" } }, { "code": "T86.1", "description": "kidney transplant failure and rejection", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "ICD-10" } }, { "code": "Y60.2", "description": "during kidney dialysis or other perfusion", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "ICD-10" } }, { "code": "Y61.2", "description": "during kidney dialysis or other perfusion", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "ICD-10" } }, { "code": "Y62.2", "description": "during kidney dialysis or other perfusion", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "ICD-10" } }, { "code": "Y84.1", "description": "kidney dialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "ICD-10" } }, { "code": "Z49", "description": "care involving dialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "ICD-10" } }, { "code": "Z49.0", "description": "preparatory care for dialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "ICD-10" } }, { "code": "Z49.1", "description": "extracorporeal dialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "ICD-10" } }, { "code": "Z49.2", "description": "other dialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "ICD-10" } }, { "code": "Z94.0", "description": "kidney transplant status", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "ICD-10" } }, { "code": "Z99.2", "description": "dependence on renal dialysis", "attributes": { "Entity type": "res30: ESRD", "Category": "diagnostic", "Coding System (ICD-10 Read)": "ICD-10" } } ] } ], "status": 2, "doi": "https://doi.org/10.48533/4zyq-jm35", "is_deleted": null, "publish_status": 2, "owner": "ieuan.scanlon", "template": { "id": 1, "name": "Clinical-Coded Phenotype", "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.", "version_id": 1 }, "versions": [ { "version_id": 1148, "version_name": "End-Stage Renal Disease (ESRD)", "version_date": "2021-10-06T16:25:27.581068Z", "is_published": true, "is_latest": true } ] } ]