[ { "phenotype_id": "PH608", "phenotype_version_id": 1216, "name": "Rheumatoid Arthritis", "definition": "Methods: \n\nWe examined EHRs of 5,843 patients in the General Practice Research Database, aged $30y, with a first coded diagnosis of RA between 2005 and 2008. Lists of indicator markers for RA were developed initially by panels of clinicians drawing up code-lists and then modified based on scrutiny of available data. The prevalence of indicator markers, and their temporal relationship to RA codes, was examined in patients from 3y before to 14d after recorded RA diagnosis.\n\n\nFindings: \n\nIndicator markers were common throughout EHRs of RA patients, with 83.5% having 2 or more markers. 34% of patients received a disease-specific prescription before RA was coded; 42% had a referral to rheumatology, and 63% had a test for rheumatoid factor. 65% had at least one joint symptom or sign recorded and in 44% this was at least 6-months before recorded RA diagnosis.\n\n\n\n\n\n\n\n\n", "implementation": "", "publications": [ { "doi": null, "details": "Amanda Nicholson, Elizabeth Ford, Kevin A Davies, Helen E Smith, Greta Rait, A Rosemary Tate, Irene Petersen, Jackie Cassell, Optimising Use of Electronic Health Records to Describe the Presentation of Rheumatoid Arthritis in Primary Care A Strategy for Developing Code Lists. PLoS ONE, 8:2, 2013." } ], "validation": "", "citation_requirements": "", "created": "2021-10-06T16:26:40.066975Z", "author": "Amanda Nicholson, Elizabeth Ford, Kevin A Davies, Helen E Smith, Greta Rait, A Rosemary Tate, Irene Petersen, Jackie Cassell", "collections": [ { "name": "ClinicalCodes Repository", "value": 25 }, { "name": "Phenotype Library", "value": 18 } ], "tags": null, "organisation": null, "world_access": 1, "updated": "2021-10-06T16:26:40.067003Z", "sex": [ { "name": "Both", "value": "3" } ], "type": [ { "name": "Disease or syndrome", "value": "2" } ], "ontology": null, "phenoflowid": "", "data_sources": [ { "name": "CPRD GOLD", "value": 5, "uid": "a29feafa-7bdd-44e9-b977-c9d26425e67f", "url": "https://healthdatagateway.org/en/dataset/694", "datasource_id": 694 } ], "coding_system": [ { "name": "Read codes v2", "value": 5 } ], "event_date_range": "01/01/2005 - 31/12/2008", "concept_information": [ { "concept_id": 2013, "concept_version_id": 5164, "concept_name": "Rheumatoid Arthritis - Primary Care", "coding_system": { "id": 5, "name": "Read codes v2", "description": "Read codes v2" }, "phenotype_id": "PH608", "phenotype_version_id": 1216, "phenotype_name": "Rheumatoid Arthritis", "code_attribute_header": [ "Entity type", "Category", "Coding System (Read)" ], "codes": [ { "code": "2G25.00", "description": "O/E - hands - ulnar deviation", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "2G25.11", "description": "O/E - ulnar deviation", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "2G27.00", "description": "O/E-hands-rheumatoid spindling", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "66H..13", "description": "Rheumatoid arthrit. monitoring", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "F371200", "description": "Polyneuropathy in rheumatoid arthritis", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "F396400", "description": "Myopathy due to rheumatoid arthritis", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G5y8.00", "description": "Rheumatoid myocarditis", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "G5yA.00", "description": "Rheumatoid carditis", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "H570.00", "description": "Rheumatoid lung", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N005.00", "description": "Adult Still's Disease", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N04..00", "description": "Rheumatoid arthritis and other inflammatory polyarthropathy", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N040.00", "description": "Rheumatoid arthritis", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N040000", "description": "Rheumatoid arthritis of cervical spine", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N040100", "description": "Other rheumatoid arthritis of spine", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N040200", "description": "Rheumatoid arthritis of shoulder", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N040500", "description": "Rheumatoid arthritis of elbow", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N040600", "description": "Rheumatoid arthritis of distal radio-ulnar joint", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N040700", "description": "Rheumatoid arthritis of wrist", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N040800", "description": "Rheumatoid arthritis of MCP joint", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N040900", "description": "Rheumatoid arthritis of PIP joint of finger", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N040A00", "description": "Rheumatoid arthritis of DIP joint of finger", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N040B00", "description": "Rheumatoid arthritis of hip", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N040D00", "description": "Rheumatoid arthritis of knee", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N040F00", "description": "Rheumatoid arthritis of ankle", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N040G00", "description": "Rheumatoid arthritis of subtalar joint", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N040H00", "description": "Rheumatoid arthritis of talonavicular joint", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N040J00", "description": "Rheumatoid arthritis of other tarsal joint", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N040K00", "description": "Rheumatoid arthritis of 1st MTP joint", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N040N00", "description": "Rheumatoid vasculitis", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N040P00", "description": "Seronegative rheumatoid arthritis", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N040Q00", "description": "Rheumatoid bursitis", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N040R00", "description": "Rheumatoid nodule", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N040S00", "description": "Rheumatoid arthritis - multiple joint", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N040T00", "description": "Flare of rheumatoid arthritis", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N041.00", "description": "Felty's syndrome", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N042.00", "description": "Other rheumatoid arthropathy + visceral/systemic involvement", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N042100", "description": "Rheumatoid lung disease", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N042200", "description": "Rheumatoid nodule", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N042z00", "description": "Rheumatoid arthropathy + visceral/systemic involvement NOS", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N043.00", "description": "Juvenile rheumatoid arthritis - Still's disease", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N043000", "description": "Juvenile rheumatoid arthropathy unspecified", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N043100", "description": "Acute polyarticular juvenile rheumatoid arthritis", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N043200", "description": "Pauciarticular juvenile rheumatoid arthritis", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N043300", "description": "Monarticular juvenile rheumatoid arthritis", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N043z00", "description": "Juvenile rheumatoid arthritis NOS", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N045.00", "description": "Other juvenile arthritis", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N045000", "description": "Juvenile ankylosing spondylitis", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N045100", "description": "Juvenile seronegative polyarthritis", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N045500", "description": "Juvenile rheumatoid arthritis", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N045600", "description": "Pauciarticular onset juvenile chronic arthritis", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N047.00", "description": "Seropositive errosive rheumatoid arthritis", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N04X.00", "description": "Seropositive rheumatoid arthritis; unspecified", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N04y000", "description": "Rheumatoid lung", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N04y011", "description": "Caplan's syndrome", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N04y012", "description": "Fibrosing alveolitis associated with rheumatoid arthritis", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N04y200", "description": "Adult-onset Still's disease", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "N362200", "description": "Swan-neck finger deformity", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "Nyu1100", "description": "[X]Other seropositive rheumatoid arthritis", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "Nyu1200", "description": "[X]Other specified rheumatoid arthritis", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "Nyu1500", "description": "[X]Other juvenile arthritis", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "Nyu1G00", "description": "[X]Seropositive rheumatoid arthritis; unspecified", "attributes": { "Entity type": "res13: Rheumatoid Arthritis", "Category": "diagnostic", "Coding System (Read)": "Read" } } ] } ], "status": 2, "doi": "https://doi.org/10.48533/61sd-e538", "is_deleted": null, "publish_status": 2, "owner": "ieuan.scanlon", "template": { "id": 1, "name": "Clinical-Coded Phenotype", "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.", "version_id": 1 }, "versions": [ { "version_id": 1216, "version_name": "Rheumatoid Arthritis", "version_date": "2021-10-06T16:26:40.094296Z", "is_published": true, "is_latest": true } ] } ]