[ { "phenotype_id": "PH62", "phenotype_version_id": 124, "name": "Motor neuron disease", "definition": "At the specified date, a patient is defined as having had motor neuron disease IF they meet the criteria for any of the following on or before the specified date. The earliest date on which the individual meets any of the following criteria on or before the specified date is defined as the first event date:\n\n\nPrimary care\n\n\n1. Motor neuron disease diagnosis or history of diagnosis during a consultation \n\nOR\nSecondary care\n\n\n1. ALL diagnoses of motor neuron disease or history of diagnosis during a hospitalization\n\n\n\n\n\n\n\n\n\n\n\n\n", "implementation": "", "publications": [ { "doi": "10.1016/S2589-7500(19)30012-3", "details": "Kuan V., Denaxas S., Gonzalez-Izquierdo A. et al. A chronological map of 308 physical and mental health conditions from 4 million individuals in the National Health Service. The Lancet Digital Health - DOI 10.1016/S2589-7500(19)30012-3" } ], "validation": "", "citation_requirements": "", "created": "2021-10-06T16:01:28.119909Z", "author": "Kuan V, Denaxas S, Gonzalez-Izquierdo A, Direk K, Bhatti O, Husain S, Sutaria S, Hingorani M, Nitsch D, Parisinos C, Lumbers T, Mathur R, Sofat R, Casas JP, Wong I, Hemingway H, Hingorani A", "collections": [ { "name": "CALIBER", "value": 21 }, { "name": "Phenotype Library", "value": 18 } ], "tags": null, "organisation": null, "world_access": 1, "updated": "2021-10-06T16:01:28.119938Z", "sex": [ { "name": "Both", "value": "3" } ], "type": [ { "name": "Disease or syndrome", "value": "2" } ], "ontology": null, "phenoflowid": "https://kclhi.org/phenoflow/workflows/github.com/phenoflow/Motor-neuron-disease---ecfbb9b0-174f-11ef-9de4-4d4ea830ad16/blob/read-potential-cases-fhir/Motor-neuron-disease.cwl", "data_sources": [ { "name": "CPRD GOLD", "value": 5, "uid": "a29feafa-7bdd-44e9-b977-c9d26425e67f", "url": "https://healthdatagateway.org/en/dataset/694", "datasource_id": 694 }, { "name": "HES Admitted Patient Care data for CPRD GOLD", "value": 9, "uid": "4bcf64a6-f404-4ef4-ae6e-172512ab5f43", "url": "https://healthdatagateway.org/en/dataset/674", "datasource_id": 674 } ], "coding_system": [ { "name": "ICD10 codes", "value": 4 }, { "name": "Read codes v2", "value": 5 }, { "name": "Med codes", "value": 8 } ], "event_date_range": "01/01/1999 - 01/07/2016", "concept_information": [ { "concept_id": 852, "concept_version_id": 2843, "concept_name": "Motor neuron disease - Primary care", "coding_system": { "id": 5, "name": "Read codes v2", "description": "Read codes v2" }, "phenotype_id": "PH62", "phenotype_version_id": 124, "phenotype_name": "Motor neuron disease", "code_attribute_header": [ "Disease", "Medcode", "Category" ], "codes": [ { "code": "7Q04100", "description": "Amyotrophic lateral sclerosis drugs Band 1", "attributes": { "Disease": "Motor neuron disease", "Medcode": "109020.0", "Category": "History of Motor neuron disease" } }, { "code": "F15..00", "description": "Anterior horn cell disease", "attributes": { "Disease": "Motor neuron disease", "Medcode": "21889.0", "Category": "Diagnosis of Motor neuron disease" } }, { "code": "F152.00", "description": "Motor neurone disease", "attributes": { "Disease": "Motor neuron disease", "Medcode": "4796.0", "Category": "Diagnosis of Motor neuron disease" } }, { "code": "F152000", "description": "Amyotrophic lateral sclerosis", "attributes": { "Disease": "Motor neuron disease", "Medcode": "36433.0", "Category": "Diagnosis of Motor neuron disease" } }, { "code": "F152100", "description": "Progressive muscular atrophy", "attributes": { "Disease": "Motor neuron disease", "Medcode": "30987.0", "Category": "Diagnosis of Motor neuron disease" } }, { "code": "F152111", "description": "Duchenne Aran muscular atrophy", "attributes": { "Disease": "Motor neuron disease", "Medcode": "7470.0", "Category": "Diagnosis of Motor neuron disease" } }, { "code": "F152200", "description": "Progressive bulbar palsy", "attributes": { "Disease": "Motor neuron disease", "Medcode": "27377.0", "Category": "Diagnosis of Motor neuron disease" } }, { "code": "F152300", "description": "Pseudobulbar palsy", "attributes": { "Disease": "Motor neuron disease", "Medcode": "18084.0", "Category": "Diagnosis of Motor neuron disease" } }, { "code": "F152400", "description": "Primary lateral sclerosis", "attributes": { "Disease": "Motor neuron disease", "Medcode": "20845.0", "Category": "Diagnosis of Motor neuron disease" } }, { "code": "F152z00", "description": "Motor neurone disease NOS", "attributes": { "Disease": "Motor neuron disease", "Medcode": "20120.0", "Category": "Diagnosis of Motor neuron disease" } }, { "code": "F15y.00", "description": "Other anterior horn cell disease", "attributes": { "Disease": "Motor neuron disease", "Medcode": "71400.0", "Category": "Diagnosis of Motor neuron disease" } }, { "code": "F15z.00", "description": "Anterior horn cell disease NOS", "attributes": { "Disease": "Motor neuron disease", "Medcode": "58729.0", "Category": "Diagnosis of Motor neuron disease" } } ] }, { "concept_id": 853, "concept_version_id": 2845, "concept_name": "Motor neuron disease - Primary care", "coding_system": { "id": 8, "name": "Med codes", "description": "Med codes" }, "phenotype_id": "PH62", "phenotype_version_id": 124, "phenotype_name": "Motor neuron disease", "code_attribute_header": [ "Disease", "ReadcodeDescr", "Readcode" ], "codes": [ { "code": "109020.0", "description": "History of Motor neuron disease", "attributes": { "Disease": "Motor neuron disease", "ReadcodeDescr": "Amyotrophic lateral sclerosis drugs Band 1", "Readcode": "7Q04100" } }, { "code": "18084.0", "description": "Diagnosis of Motor neuron disease", "attributes": { "Disease": "Motor neuron disease", "ReadcodeDescr": "Pseudobulbar palsy", "Readcode": "F152300" } }, { "code": "20120.0", "description": "Diagnosis of Motor neuron disease", "attributes": { "Disease": "Motor neuron disease", "ReadcodeDescr": "Motor neurone disease NOS", "Readcode": "F152z00" } }, { "code": "20845.0", "description": "Diagnosis of Motor neuron disease", "attributes": { "Disease": "Motor neuron disease", "ReadcodeDescr": "Primary lateral sclerosis", "Readcode": "F152400" } }, { "code": "21889.0", "description": "Diagnosis of Motor neuron disease", "attributes": { "Disease": "Motor neuron disease", "ReadcodeDescr": "Anterior horn cell disease", "Readcode": "F15..00" } }, { "code": "27377.0", "description": "Diagnosis of Motor neuron disease", "attributes": { "Disease": "Motor neuron disease", "ReadcodeDescr": "Progressive bulbar palsy", "Readcode": "F152200" } }, { "code": "30987.0", "description": "Diagnosis of Motor neuron disease", "attributes": { "Disease": "Motor neuron disease", "ReadcodeDescr": "Progressive muscular atrophy", "Readcode": "F152100" } }, { "code": "36433.0", "description": "Diagnosis of Motor neuron disease", "attributes": { "Disease": "Motor neuron disease", "ReadcodeDescr": "Amyotrophic lateral sclerosis", "Readcode": "F152000" } }, { "code": "4796.0", "description": "Diagnosis of Motor neuron disease", "attributes": { "Disease": "Motor neuron disease", "ReadcodeDescr": "Motor neurone disease", "Readcode": "F152.00" } }, { "code": "58729.0", "description": "Diagnosis of Motor neuron disease", "attributes": { "Disease": "Motor neuron disease", "ReadcodeDescr": "Anterior horn cell disease NOS", "Readcode": "F15z.00" } }, { "code": "71400.0", "description": "Diagnosis of Motor neuron disease", "attributes": { "Disease": "Motor neuron disease", "ReadcodeDescr": "Other anterior horn cell disease", "Readcode": "F15y.00" } }, { "code": "7470.0", "description": "Diagnosis of Motor neuron disease", "attributes": { "Disease": "Motor neuron disease", "ReadcodeDescr": "Duchenne Aran muscular atrophy", "Readcode": "F152111" } } ] }, { "concept_id": 854, "concept_version_id": 2847, "concept_name": "Motor neuron disease - Secondary care - Diagnoses", "coding_system": { "id": 4, "name": "ICD10 codes", "description": "ICD10 Codes" }, "phenotype_id": "PH62", "phenotype_version_id": 124, "phenotype_name": "Motor neuron disease", "code_attribute_header": [ "Disease", "Category" ], "codes": [ { "code": "G12.2", "description": "Motor neuron disease", "attributes": { "Disease": "Motor neuron disease", "Category": "Diagnosis of Motor neuron disease" } } ] } ], "status": 2, "doi": "https://doi.org/10.48533/fjx9-mb56", "is_deleted": null, "publish_status": 2, "owner": "ieuan.scanlon", "template": { "id": 1, "name": "Clinical-Coded Phenotype", "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.", "version_id": 1 }, "versions": [ { "version_id": 124, "version_name": "Motor neuron disease", "version_date": "2021-10-06T16:01:28.150356Z", "is_published": true, "is_latest": true } ] } ]