[ { "phenotype_id": "PH626", "phenotype_version_id": 1252, "name": "Chronic Kidney Disease (CKD)", "definition": "Objectives: \n\nLittle is known about the prevalence of comorbidity rates in people with severe mental illness (SMI) in UK primary care. We calculated the prevalence of SMI by UK country, English region and deprivation quintile, antipsychotic and antidepressant medication prescription rates for people with SMI, and prevalence rates of common comorbidities in people with SMI compared with people without SMI.\n\n\nDesign: \n\nRetrospective cohort study from 2000 to 2012.\n\n\nSetting: \n\n627 general practices contributing to the Clinical Practice Research Datalink, a UK primary care database.\n\n\nParticipants: \n\nEach identified case (346 551) was matched for age, sex and general practice with 5 randomly selected control cases (1 732 755) with no diagnosis of SMI in each yearly time point.\n\n\nOutcome measures: \n\nPrevalence rates were calculated for 16 conditions.\n\n\n\n\n\n\n\n\n", "implementation": "", "publications": [ { "doi": null, "details": "Siobhan Reilly, Ivan Olier, Claire Planner, Tim Doran, David Reeves, Darren M Ashcroft, Linda Gask, Evangelos Kontopantelis, Inequalities in physical comorbidity a longitudinal comparative cohort study of people with severe mental illness in the UK. BMJ Open, 5(e009010), 2015." } ], "validation": "", "citation_requirements": "", "created": "2021-10-06T16:27:33.236480Z", "author": "Siobhan Reilly, Ivan Olier, Claire Planner, Tim Doran, David Reeves, Darren M Ashcroft, Linda Gask, Evangelos Kontopantelis", "collections": [ { "name": "ClinicalCodes Repository", "value": 25 }, { "name": "Phenotype Library", "value": 18 } ], "tags": null, "organisation": null, "world_access": 1, "updated": "2021-10-06T16:27:33.236507Z", "sex": [ { "name": "Male", "value": "1" } ], "type": [ { "name": "Disease or syndrome", "value": "2" } ], "ontology": null, "phenoflowid": "", "data_sources": [ { "name": "CPRD GOLD", "value": 5, "uid": "a29feafa-7bdd-44e9-b977-c9d26425e67f", "url": "https://healthdatagateway.org/en/dataset/694", "datasource_id": 694 } ], "coding_system": [ { "name": "Read codes v2", "value": 5 } ], "event_date_range": "01/04/2000 - 31/03/2012", "concept_information": [ { "concept_id": 2035, "concept_version_id": 5208, "concept_name": "Chronic Kidney Disease (CKD) - Primary Care", "coding_system": { "id": 5, "name": "Read codes v2", "description": "Read codes v2" }, "phenotype_id": "PH626", "phenotype_version_id": 1252, "phenotype_name": "Chronic Kidney Disease (CKD)", "code_attribute_header": [ "Entity type", "Category", "Coding System (Read)" ], "codes": [ { "code": "1Z12.00", "description": "Chronic kidney disease stage 3", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1Z13.00", "description": "Chronic kidney disease stage 4", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1Z14.00", "description": "Chronic kidney disease stage 5", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1Z15.00", "description": "Chronic kidney disease stage 3A", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1Z16.00", "description": "Chronic kidney disease stage 3B", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1Z1B.00", "description": "Chronic kidney disease stage 3 with proteinuria", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1Z1C.00", "description": "Chronic kidney disease stage 3 without proteinuria", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1Z1D.00", "description": "Chronic kidney disease stage 3A with proteinuria", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1Z1E.00", "description": "Chronic kidney disease stage 3A without proteinuria", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1Z1F.00", "description": "Chronic kidney disease stage 3B with proteinuria", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1Z1G.00", "description": "Chronic kidney disease stage 3B without proteinuria", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1Z1H.00", "description": "Chronic kidney disease stage 4 with proteinuria", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1Z1J.00", "description": "Chronic kidney disease stage 4 without proteinuria", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1Z1K.00", "description": "Chronic kidney disease stage 5 with proteinuria", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1Z1L.00", "description": "Chronic kidney disease stage 5 without proteinuria", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "7B06300", "description": "Exploration of renal transplant", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "8L50.00", "description": "Renal transplant planned", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K01..00", "description": "Nephrotic syndrome", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K010.00", "description": "Nephrotic syndrome with proliferative glomerulonephritis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K011.00", "description": "Nephrotic syndrome with membranous glomerulonephritis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K012.00", "description": "Nephrotic syndrome+membranoproliferative glomerulonephritis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K013.00", "description": "Nephrotic syndrome with minimal change glomerulonephritis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K013.11", "description": "Lipoid nephrosis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K013.12", "description": "Steroid sensitive nephrotic syndrome", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K014.00", "description": "Nephrotic syndrome, minor glomerular abnormality", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K015.00", "description": "Nephrotic syndrome, focal and segmental glomerular lesions", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K016.00", "description": "Nephrotic syndrome, diffuse membranous glomerulonephritis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K017.00", "description": "Nephrotic syn difus mesangial prolifertiv glomerulonephritis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K018.00", "description": "Nephrotic syn,difus endocapilary proliftv glomerulonephritis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K019.00", "description": "Nephrotic syn,diffuse mesangiocapillary glomerulonephritis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K01A.00", "description": "Nephrotic syndrome, dense deposit disease", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K01B.00", "description": "Nephrotic syndrome, diffuse crescentic glomerulonephritis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K01w.00", "description": "Congenital nephrotic syndrome", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K01w000", "description": "Finnish nephrosis syndrome", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K01x000", "description": "Nephrotic syndrome in amyloidosis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K01x100", "description": "Nephrotic syndrome in diabetes mellitus", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K01x111", "description": "Kimmelstiel - Wilson disease", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K01x200", "description": "Nephrotic syndrome in malaria", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K01x300", "description": "Nephrotic syndrome in polyarteritis nodosa", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K01x400", "description": "Nephrotic syndrome in systemic lupus erythematosus", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K01x411", "description": "Lupus nephritis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K01y.00", "description": "Nephrotic syndrome with other pathological kidney lesions", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K01z.00", "description": "Nephrotic syndrome NOS", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K02..00", "description": "Chronic glomerulonephritis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K020.00", "description": "Chronic proliferative glomerulonephritis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K021.00", "description": "Chronic membranous glomerulonephritis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K02..11", "description": "Nephritis - chronic", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K02..12", "description": "Nephropathy - chronic", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K022.00", "description": "Chronic membranoproliferative glomerulonephritis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K023.00", "description": "Chronic rapidly progressive glomerulonephritis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K02y.00", "description": "Other chronic glomerulonephritis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K02y000", "description": "Chronic glomerulonephritis + diseases EC", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K02y200", "description": "Chronic focal glomerulonephritis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K02y300", "description": "Chronic diffuse glomerulonephritis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K02yz00", "description": "Other chronic glomerulonephritis NOS", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K02z.00", "description": "Chronic glomerulonephritis NOS", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K05..00", "description": "Chronic renal failure", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K050.00", "description": "End stage renal failure", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K05..11", "description": "Chronic uraemia", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K05..12", "description": "End stage renal failure", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K0D..00", "description": "End-stage renal disease", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K100.00", "description": "Chronic pyelonephritis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K100000", "description": "Chronic pyelonephritis without medullary necrosis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K100100", "description": "Chronic pyelonephritis with medullary necrosis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K100200", "description": "Chronic pyelitis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K100300", "description": "Chronic pyonephrosis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K100400", "description": "Nonobstructive reflux-associated chronic pyelonephritis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K100500", "description": "Chronic obstructive pyelonephritis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K100600", "description": "Calculous pyelonephritis", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "K100z00", "description": "Chronic pyelonephritis NOS", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "SP08300", "description": "Kidney transplant failure and rejection", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "TB00100", "description": "Kidney transplant with complication, without blame", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "TB00111", "description": "Renal transplant with complication, without blame", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "ZV42000", "description": "[V]Kidney transplanted", "attributes": { "Entity type": "res26: CKD", "Category": "diagnostic", "Coding System (Read)": "Read" } } ] } ], "status": 2, "doi": "https://doi.org/10.48533/e447-vc56", "is_deleted": null, "publish_status": 2, "owner": "ieuan.scanlon", "template": { "id": 1, "name": "Clinical-Coded Phenotype", "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.", "version_id": 1 }, "versions": [ { "version_id": 1252, "version_name": "Chronic Kidney Disease (CKD)", "version_date": "2021-10-06T16:27:33.264104Z", "is_published": true, "is_latest": true } ] } ]