[ { "phenotype_id": "PH633", "phenotype_version_id": 1266, "name": "Hypothyroidism", "definition": "Objectives: \n\nLittle is known about the prevalence of comorbidity rates in people with severe mental illness (SMI) in UK primary care. We calculated the prevalence of SMI by UK country, English region and deprivation quintile, antipsychotic and antidepressant medication prescription rates for people with SMI, and prevalence rates of common comorbidities in people with SMI compared with people without SMI.\n\n\nDesign: \n\nRetrospective cohort study from 2000 to 2012.\n\n\nSetting: \n\n627 general practices contributing to the Clinical Practice Research Datalink, a UK primary care database.\n\n\nParticipants: \n\nEach identified case (346 551) was matched for age, sex and general practice with 5 randomly selected control cases (1 732 755) with no diagnosis of SMI in each yearly time point.\n\n\nOutcome measures: \n\nPrevalence rates were calculated for 16 conditions.\n\n\n\n\n\n\n\n\n", "implementation": "", "publications": [ { "doi": null, "details": "Siobhan Reilly, Ivan Olier, Claire Planner, Tim Doran, David Reeves, Darren M Ashcroft, Linda Gask, Evangelos Kontopantelis, Inequalities in physical comorbidity a longitudinal comparative cohort study of people with severe mental illness in the UK. BMJ Open, 5(e009010), 2015." } ], "validation": "", "citation_requirements": "", "created": "2021-10-06T16:27:48.801578Z", "author": "Siobhan Reilly, Ivan Olier, Claire Planner, Tim Doran, David Reeves, Darren M Ashcroft, Linda Gask, Evangelos Kontopantelis", "collections": [ { "name": "ClinicalCodes Repository", "value": 25 }, { "name": "Phenotype Library", "value": 18 } ], "tags": null, "organisation": null, "world_access": 1, "updated": "2021-10-06T16:27:48.801606Z", "sex": [ { "name": "Male", "value": "1" } ], "type": [ { "name": "Disease or syndrome", "value": "2" } ], "ontology": null, "phenoflowid": "", "data_sources": [ { "name": "CPRD GOLD", "value": 5, "uid": "a29feafa-7bdd-44e9-b977-c9d26425e67f", "url": "https://healthdatagateway.org/en/dataset/694", "datasource_id": 694 } ], "coding_system": [ { "name": "Read codes v2", "value": 5 }, { "name": "OXMIS codes", "value": 15 } ], "event_date_range": "01/04/2000 - 31/03/2012", "concept_information": [ { "concept_id": 2048, "concept_version_id": 5234, "concept_name": "Hypothyroidism - Primary Care", "coding_system": { "id": 5, "name": "Read codes v2", "description": "Read codes v2" }, "phenotype_id": "PH633", "phenotype_version_id": 1266, "phenotype_name": "Hypothyroidism", "code_attribute_header": [ "Entity type", "Coding System (OXMIS Read)", "Category" ], "codes": [ { "code": "C03..00", "description": "Congenital hypothyroidism", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C03y.00", "description": "Other specified congenital hypothyroidism", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C03y000", "description": "Congenital hypothyroidism with diffuse goitre", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C03y100", "description": "Congenital hypothyroidism without goitre", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C03z.00", "description": "Congenital hypothyroidism NOS", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C04..00", "description": "Acquired hypothyroidism", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C040.00", "description": "Postsurgical hypothyroidism", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C040.11", "description": "Post ablative hypothyroidism", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C041.00", "description": "Other postablative hypothyroidism", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C041000", "description": "Irradiation hypothyroidism", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C04..11", "description": "Myxoedema", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C04..12", "description": "Thyroid deficiency", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C04..13", "description": "Hypothyroidism", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C041z00", "description": "Postablative hypothyroidism NOS", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C042.00", "description": "Iodine hypothyroidism", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C043.00", "description": "Other iatrogenic hypothyroidism", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C043000", "description": "Hypothyroidism resulting from para-aminosalicylic acid", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C043100", "description": "Hypothyroidism resulting from phenylbutazone", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C043200", "description": "Hypothyroidism resulting from resorcinol", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C043z00", "description": "Iatrogenic hypothyroidism NOS", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C044.00", "description": "Postinfectious hypothyroidism", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C045.00", "description": "Acquired atrophy of thyroid", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C046.00", "description": "Autoimmune myxoedema", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C04y.00", "description": "Other acquired hypothyroidism", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C04z.00", "description": "Hypothyroidism NOS", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C04z000", "description": "Premature puberty due to hypothyroidism", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C04z100", "description": "Myxoedema coma", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C04z.11", "description": "Pretibial myxoedema - hypothyroid", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C04z.12", "description": "Thyroid insufficiency", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "C04z.13", "description": "Hypothyroid goitre, acquired", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } }, { "code": "Cyu1100", "description": "[X]Other sp cified hypothyroidism", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "Read", "Category": "diagnostic" } } ] }, { "concept_id": 2049, "concept_version_id": 5236, "concept_name": "Hypothyroidism - Primary Care", "coding_system": { "id": 15, "name": "OXMIS codes", "description": "OXMIS codes" }, "phenotype_id": "PH633", "phenotype_version_id": 1266, "phenotype_name": "Hypothyroidism", "code_attribute_header": [ "Entity type", "Coding System (OXMIS Read)", "Category" ], "codes": [ { "code": "243", "description": "HYPOTHYROIDISM CONGENITAL", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "OXMIS", "Category": "diagnostic" } }, { "code": "244 AC", "description": "HYPOTHYROIDISM ACQUIRED", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "OXMIS", "Category": "diagnostic" } }, { "code": "244 AG", "description": "HYPOTHYROIDISM COMPENSATED", "attributes": { "Entity type": "res26: Hypothyroidism", "Coding System (OXMIS Read)": "OXMIS", "Category": "diagnostic" } } ] } ], "status": 2, "doi": "https://doi.org/10.48533/q3jt-we32", "is_deleted": null, "publish_status": 2, "owner": "ieuan.scanlon", "template": { "id": 1, "name": "Clinical-Coded Phenotype", "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.", "version_id": 1 }, "versions": [ { "version_id": 1266, "version_name": "Hypothyroidism", "version_date": "2021-10-06T16:27:48.828615Z", "is_published": true, "is_latest": true } ] } ]